vinblastin (BioDeep_00000015125)
PANOMIX_OTCML-2023
代谢物信息卡片
Vinblastine
化学式: C46H58N4O9 (810.4204)
中文名称: 长春质碱, 长春罗定
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 100%
分子结构信息
SMILES: CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O
InChI: InChI=1S/C46H58N4O9/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3
描述信息
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01C - Plant alkaloids and other natural products > L01CA - Vinca alkaloids and analogues
D050258 - Mitosis Modulators > D050256 - Antimitotic Agents > D050257 - Tubulin Modulators
D000970 - Antineoplastic Agents > D050256 - Antimitotic Agents
D000970 - Antineoplastic Agents > D014748 - Vinca Alkaloids
同义名列表
6 个代谢物同义名
Vinblastine; Vinrosidine; vinblastin; Leurosidine; Vinblastine; Leurosidine
数据库引用编号
18 个数据库交叉引用编号
- ChEBI: CHEBI:125454
- ChEBI: CHEBI:6429
- KEGG: C09218
- PubChem: 3823887
- PubChem: 442110
- ChEMBL: CHEMBL4788494
- MeSH: Vinblastine
- CAS: 15228-71-4
- CAS: 865-21-4
- MetaboLights: MTBLC6429
- PubChem: 11409
- KNApSAcK: C00001743
- 3DMET: B02775
- NIKKAJI: J370.581A
- KEGG: C07201
- PubChem: 9410
- KNApSAcK: 27375
- KNApSAcK: 6429
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Masoomeh Nabaei, Rayhaneh Amooaghaie, Mansour Ghorbanpour, Alimohammad Ahadi. Crosstalk between melatonin and nitric oxide restrains Cadmium-induced oxidative stress and enhances vinblastine biosynthesis in Catharanthus roseus (L) G Don.
Plant cell reports.
2024 May; 43(6):139. doi:
10.1007/s00299-024-03229-4. [PMID: 38735908] - Pooja Singh, Seema Yadav, Saumya Shah, Karuna Shanker, Velusamy Sundaresan, Ashutosh K Shukla. Characterization of a CrPME indicates its possible role in determining vindoline accumulation in Catharanthus roseus leaves.
Physiologia plantarum.
2024 Mar; 176(2):e14276. doi:
10.1111/ppl.14276. [PMID: 38566244] - Jun Guo, Di Gao, Jiazhang Lian, Yang Qu. De novo biosynthesis of antiarrhythmic alkaloid ajmaline.
Nature communications.
2024 Jan; 15(1):457. doi:
10.1038/s41467-024-44797-z. [PMID: 38212296] - Jawad Ahmed, Yasar Sajjad, Aasia Latif, Mohammad Saeed Lodhi, Muhammad Huzafa, Chen Situ, Raza Ahmad, Muhammad Maroof Shah, Amjad Hassan. Genome-wide identification and characterization of wall-associated kinases, molecular docking and polysaccharide elicitation of monoterpenoid indole alkaloids in micro-propagated Catharanthus roseus.
Journal of plant research.
2024 Jan; 137(1):125-142. doi:
10.1007/s10265-023-01504-1. [PMID: 37962734] - Zhongping Xu, Guanying Wang, Qiongqiong Wang, Xiaoting Li, Guangyu Zhang, Ali Qurban, Can Zhang, Yi Zhou, Huan Si, Lisong Hu, Fuqiu Wang, Ying Wang, Zhitao Tian, Wei Chen, Shuangxia Jin, Fang Ding. A near-complete genome assembly of Catharanthus roseus and insights into its vinblastine biosynthesis and high susceptibility to the Huanglongbing pathogen.
Plant communications.
2023 Nov; 4(6):100661. doi:
10.1016/j.xplc.2023.100661. [PMID: 37464741] - Maneesha Mall, Karuna Shanker, Dinesh A Nagegowda, Abdul Samad, Alok Kalra, Alok Pandey, Velusamy Sundaresan, Ashutosh K Shukla. Temperature-induced lipocalin-mediated membrane integrity: Possible implications for vindoline accumulation in Catharanthus roseus leaves.
Physiologia plantarum.
2023 Sep; 175(5):e13994. doi:
10.1111/ppl.13994. [PMID: 37882277] - Katalin Nagy, Éva Darkó, Gabriella Szalai, Tibor Janda, Zsuzsa Jókai, Márta Ladányi, Mohamed Ramadan Rady, Mihály Dernovics. UPLC-ESI-QTOF-MS assisted targeted metabolomics to study the enrichment of vinca alkaloids and related metabolites in Catharanthus roseus plants grown under controlled LED environment.
Journal of pharmaceutical and biomedical analysis.
2023 Jul; 235(?):115611. doi:
10.1016/j.jpba.2023.115611. [PMID: 37542828] - Hossam S El-Beltagi, Salwa M El-Sayed, Ahmed N Abdelhamid, Karim M Hassan, Walaa A Elshalakany, Mona Ibrahim Nossier, Nadiyah M Alabdallah, Nadi Awad Al-Harbi, Salem Mesfir Al-Qahtani, Doaa Bahaa Eldin Darwish, Zahid Khorshid Abbas, Hemmat A Ibrahim. Potentiating Biosynthesis of Alkaloids and Polyphenolic Substances in Catharanthus roseus Plant Using ĸ-Carrageenan.
Molecules (Basel, Switzerland).
2023 Apr; 28(8):. doi:
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Plant physiology and biochemistry : PPB.
2023 Feb; 196(?):783-792. doi:
10.1016/j.plaphy.2023.02.039. [PMID: 36848864] - Valentina Laghezza Masci, Davide Stefanoni, Angelo D'Alessandro, Marta Zambelli, Lorenzo Modesti, Daniele Pollini, Elisa Ovidi, Antonio Tiezzi. Induction of Drug-Resistance and Production of a Culture Medium Able to Induce Drug-Resistance in Vinblastine Untreated Murine Myeloma Cells.
Molecules (Basel, Switzerland).
2023 Feb; 28(5):. doi:
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ACS synthetic biology.
2023 01; 12(1):27-34. doi:
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Phytochemistry.
2022 Nov; 203(?):113422. doi:
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Molecular biology reports.
2022 Nov; 49(11):10357-10365. doi:
10.1007/s11033-022-07841-z. [PMID: 36097118] - Armando Moreno-Velasco, Pedro de Jesús Flores-Tafoya, Mabel Fragoso-Serrano, Suzana Guimarães Leitão, Rogelio Pereda-Miranda. Resin Glycosides from Operculina hamiltonii and Their Synergism with Vinblastine in Cancer Cells.
Journal of natural products.
2022 10; 85(10):2385-2394. doi:
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Scientific reports.
2022 10; 12(1):17803. doi:
10.1038/s41598-022-20314-4. [PMID: 36280677] - A Mujib, Samar Fatima, Moien Qadir Malik. Cryo-derived plants through embryogenesis showed same levels of vinblastine and vincristine (anticancer) in Catharanthus roseus and had normal genome size.
Scientific reports.
2022 10; 12(1):16635. doi:
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Biochimica et biophysica acta. Biomembranes.
2022 10; 1864(10):184005. doi:
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Nature.
2022 09; 609(7926):341-347. doi:
10.1038/s41586-022-05157-3. [PMID: 36045295] - A Mujib, Samar Fatima, Moien Qadir Malik. Gamma ray-induced tissue responses and improved secondary metabolites accumulation in Catharanthus roseus.
Applied microbiology and biotechnology.
2022 Sep; 106(18):6109-6123. doi:
10.1007/s00253-022-12122-7. [PMID: 35962802] - Wojciech Trybus, Ewa Trybus, Teodora Król. Emodin Sensitizes Cervical Cancer Cells to Vinblastine by Inducing Apoptosis and Mitotic Death.
International journal of molecular sciences.
2022 Jul; 23(15):. doi:
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Nature communications.
2022 06; 13(1):3335. doi:
10.1038/s41467-022-31100-1. [PMID: 35680936] - L T van der Heijden, A Gebretensae, B Thijssen, L van Andel, A L Nijstad, Y Wang, H Rosing, A D R Huitema, J H Beijnen. A highly sensitive bioanalytical method for the quantification of vinblastine, vincristine, vinorelbine and 4-O-deacetylvinorelbine in human plasma using LC-MS/MS.
Journal of pharmaceutical and biomedical analysis.
2022 Jun; 215(?):114772. doi:
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Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi.
2022 05; 43(5):431-434. doi:
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Protoplasma.
2022 May; 259(3):755-773. doi:
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Applied microbiology and biotechnology.
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Marine drugs.
2022 Mar; 20(3):. doi:
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Pediatric blood & cancer.
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Methods in molecular biology (Clifton, N.J.).
2022; 2505(?):141-164. doi:
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Contrast media & molecular imaging.
2022; 2022(?):3104879. doi:
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Methods in molecular biology (Clifton, N.J.).
2022; 2505(?):181-190. doi:
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Methods in molecular biology (Clifton, N.J.).
2022; 2505(?):301-315. doi:
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Chemistry & biodiversity.
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Current problems in cancer.
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Clinical genitourinary cancer.
2021 12; 19(6):554-562. doi:
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Microbial biotechnology.
2021 11; 14(6):2693-2699. doi:
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Molecules (Basel, Switzerland).
2021 Oct; 26(21):. doi:
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Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis.
2021 Oct; 60(5):103173. doi:
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Communications biology.
2021 09; 4(1):1089. doi:
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Molecules (Basel, Switzerland).
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Nature communications.
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BJU international.
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Journal of pediatric hematology/oncology.
2021 04; 43(3):e401-e403. doi:
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International journal of clinical practice.
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BJU international.
2021 03; 127(3):332-339. doi:
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Protein and peptide letters.
2021; 28(7):735-749. doi:
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Clinical cancer research : an official journal of the American Association for Cancer Research.
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Molecules (Basel, Switzerland).
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The FEBS journal.
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Annals of hematology.
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British journal of haematology.
2020 Jul; 190(1):e1-e3. doi:
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The American journal of case reports.
2020 Jun; 21(?):e922342. doi:
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Applied microbiology and biotechnology.
2020 Jun; 104(11):4811-4835. doi:
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Analytical biochemistry.
2020 03; 593(?):113530. doi:
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Nanotechnology.
2019 Jul; 30(27):275102. doi:
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Plant physiology.
2019 07; 180(3):1336-1350. doi:
10.1104/pp.19.00489. [PMID: 31123092] - Yuki Yokota, Kazutaka Mitsuke, Hiroko Minami, Akihiko Morita, Hiromichi Takahashi, Satoshi Kamei. [Acute sensory neuropathy associated with Hodgkin's lymphoma: a case study].
Rinsho shinkeigaku = Clinical neurology.
2019 Jun; 59(6):349-355. doi:
10.5692/clinicalneurol.cn-001271. [PMID: 31142709] - Yongyan Zhu, Ruixuan Liu, Haoji Huang, Quanhong Zhu. Vinblastine-Loaded Nanoparticles with Enhanced Tumor-Targeting Efficiency and Decreasing Toxicity: Developed by One-Step Molecular Imprinting Process.
Molecular pharmaceutics.
2019 06; 16(6):2675-2689. doi:
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2019 Apr; 112(?):108638. doi:
10.1016/j.biopha.2019.108638. [PMID: 30784928] - Yang Qu, Olga Safonova, Vincenzo De Luca. Completion of the canonical pathway for assembly of anticancer drugs vincristine/vinblastine in Catharanthus roseus.
The Plant journal : for cell and molecular biology.
2019 01; 97(2):257-266. doi:
10.1111/tpj.14111. [PMID: 30256480] - Aruna Sharma, Rudy J Castellani, Mark A Smith, Dafin Fior Muresanu, Prasanta Kumar Dey, Hari Shanker Sharma. 5-Hydroxytryptophan: A precursor of serotonin influences regional blood-brain barrier breakdown, cerebral blood flow, brain edema formation, and neuropathology.
International review of neurobiology.
2019; 146(?):1-44. doi:
10.1016/bs.irn.2019.06.005. [PMID: 31349924] - Alessandro Gamboni, Claudia Casanova, Vincenzo Salerno, Claudio Dazzi. [Activity and efficacy of vinflunine in third line in patients with advanced urothelial carcinoma of the renal pelvis, progressing to immunotherapy.].
Recenti progressi in medicina.
2018 Nov; 109(11):547-550. doi:
10.1701/3031.30292. [PMID: 30565574] - Mark L Schultz, Kelsey L Krus, Susmita Kaushik, Derek Dang, Ravi Chopra, Ling Qi, Vikram G Shakkottai, Ana Maria Cuervo, Andrew P Lieberman. Coordinate regulation of mutant NPC1 degradation by selective ER autophagy and MARCH6-dependent ERAD.
Nature communications.
2018 09; 9(1):3671. doi:
10.1038/s41467-018-06115-2. [PMID: 30202070] - Lakshmi Mohan, Darpan Raghav, Shabeeba M Ashraf, Jomon Sebastian, Krishnan Rathinasamy. Indirubin, a bis-indole alkaloid binds to tubulin and exhibits antimitotic activity against HeLa cells in synergism with vinblastine.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2018 Sep; 105(?):506-517. doi:
10.1016/j.biopha.2018.05.127. [PMID: 29883946] - Abhishek Sharma, Priyanka Verma, Archana Mathur, Ajay Kumar Mathur. Overexpression of tryptophan decarboxylase and strictosidine synthase enhanced terpenoid indole alkaloid pathway activity and antineoplastic vinblastine biosynthesis in Catharanthus roseus.
Protoplasma.
2018 Sep; 255(5):1281-1294. doi:
10.1007/s00709-018-1233-1. [PMID: 29508069] - Chenghui Huang, Hui Wu, Haihua Zhu, Lan Liu, Ruifang Tian, Cong Xu, Xiaofei Li, Lihui Wang, Ke Cao, Peiguo Cao. [NAPD regimen for patients with recurrent refractory diffuse large B-cell lymphoma].
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences.
2018 Jul; 43(7):754-759. doi:
10.11817/j.issn.1672-7347.2018.07.009. [PMID: 30124211] - Lorenzo Caputi, Jakob Franke, Scott C Farrow, Khoa Chung, Richard M E Payne, Trinh-Don Nguyen, Thu-Thuy T Dang, Inês Soares Teto Carqueijeiro, Konstantinos Koudounas, Thomas Dugé de Bernonville, Belinda Ameyaw, D Marc Jones, Ivo Jose Curcino Vieira, Vincent Courdavault, Sarah E O'Connor. Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle.
Science (New York, N.Y.).
2018 06; 360(6394):1235-1239. doi:
10.1126/science.aat4100. [PMID: 29724909] - Wen-Qiong Wang, Shan-Shan Liu, Wei-Bin Song, Jun Li, Li-Jiang Xuan. Resin glycosides from the seeds of Ipomoea muricata and their multidrug resistance reversal activities.
Phytochemistry.
2018 May; 149(?):24-30. doi:
10.1016/j.phytochem.2018.01.020. [PMID: 29448078] - Caroline J Reddel, Gabrielle J Pennings, Jennifer L Curnow, Vivien M Chen, Leonard Kritharides. Procoagulant Effects of Low-Level Platelet Activation and Its Inhibition by Colchicine.
Thrombosis and haemostasis.
2018 04; 118(4):723-733. doi:
10.1055/s-0038-1636915. [PMID: 29554700] - Yang Qu, Antje M K Thamm, Matthew Czerwinski, Sayaka Masada, Kyung Hee Kim, Graham Jones, Ping Liang, Vincenzo De Luca. Geissoschizine synthase controls flux in the formation of monoterpenoid indole alkaloids in a Catharanthus roseus mutant.
Planta.
2018 Mar; 247(3):625-634. doi:
10.1007/s00425-017-2812-7. [PMID: 29147812] - Xiao-Ning Zhang, Jia Liu, Yang Liu, Yu Wang, Ann Abozeid, Zhi-Guo Yu, Zhong-Hua Tang. Metabolomics Analysis Reveals that Ethylene and Methyl Jasmonate Regulate Different Branch Pathways to Promote the Accumulation of Terpenoid Indole Alkaloids in Catharanthus roseus.
Journal of natural products.
2018 02; 81(2):335-342. doi:
10.1021/acs.jnatprod.7b00782. [PMID: 29406718] - Bilal Ahmad, Anindyajit Banerjee, Harshita Tiwari, Shrabasti Jana, Sudeshna Bose, Saikat Chakrabarti. Structural and functional characterization of the Vindoline biosynthesis pathway enzymes of Catharanthus roseus.
Journal of molecular modeling.
2018 Feb; 24(3):53. doi:
10.1007/s00894-018-3590-2. [PMID: 29442186] - Charlotte Luchsinger, Marcelo Aguilar, Patricia V Burgos, Pamela Ehrenfeld, Gonzalo A Mardones. Functional disruption of the Golgi apparatus protein ARF1 sensitizes MDA-MB-231 breast cancer cells to the antitumor drugs Actinomycin D and Vinblastine through ERK and AKT signaling.
PloS one.
2018; 13(4):e0195401. doi:
10.1371/journal.pone.0195401. [PMID: 29614107] - Lakshmi, Sanjay Singh, Mahalingam Rajamanickam Vijayakumar, Hitesh Kumar Dewangan. Lipid Based Aqueous Core Nanocapsules (ACNs) for Encapsulating Hydrophillic Vinorelbine Bitartrate: Preparation, Optimization, Characterization and In vitro Safety Assessment for Intravenous Administration.
Current drug delivery.
2018; 15(9):1284-1293. doi:
10.2174/1567201815666180716112457. [PMID: 30009708] - Alison Edge, Yang Qu, Michael L A E Easson, Antje M K Thamm, Kyung Hee Kim, Vincenzo De Luca. A tabersonine 3-reductase Catharanthus roseus mutant accumulates vindoline pathway intermediates.
Planta.
2018 Jan; 247(1):155-169. doi:
10.1007/s00425-017-2775-8. [PMID: 28894945] - Lakshmi Maurya, Sanjay Singh, Vijayakumar M Rajamanickam, Gopeshwar Narayan. Vitamin E TPGS Emulsified Vinorelbine Bitartrate Loaded Solid Lipid Nanoparticles (SLN): Formulation Development, Optimization and In vitro Characterization.
Current drug delivery.
2018; 15(8):1135-1145. doi:
10.2174/1567201815666180409105410. [PMID: 29629662] - Xiaoliang Zhao, Xiaohua Wen, Wei Wei, Yanjun Su, Jian You, Liqun Gong, Zhenfa Zhang, Meng Wang, Jianyu Xiao, Xiyin Wei, Changli Wang. Predictors for the efficacy of Endostar combined with neoadjuvant chemotherapy for stage IIIA (N2) NSCLC.
Cancer biomarkers : section A of Disease markers.
2017 Dec; 21(1):169-177. doi:
10.3233/cbm-170565. [PMID: 29036790] - A Guidetti, A Mazzocchi, R Miceli, E Paterno', F Taverna, F Spina, F Crippa, L Farina, P Corradini, A M Gianni, S Viviani. Early reduction of serum TARC levels may predict for success of ABVD as frontline treatment in patients with Hodgkin Lymphoma.
Leukemia research.
2017 11; 62(?):91-97. doi:
10.1016/j.leukres.2017.09.018. [PMID: 28992524] - Agnieszka Krawczyk, Dariusz Nowak, Piotr Jan Nowak, Gianluca Padula, Sylwia Kwiatkowska. Elevated exhalation of hydrogen peroxide in patients with non-small cell lung cancer is not affected by chemotherapy.
Redox report : communications in free radical research.
2017 Nov; 22(6):308-314. doi:
10.1080/13510002.2016.1229885. [PMID: 27611345] - Xiaobin Gong, Le Yang, Feng Zhang, Youtian Liang, Shouhong Gao, Ke Liu, Wansheng Chen. Validated UHPLC-MS/MS assay for quantitative determination of etoposide, gemcitabine, vinorelbine and their metabolites in patients with lung cancer.
Biomedical chromatography : BMC.
2017 Nov; 31(11):. doi:
10.1002/bmc.3989. [PMID: 28409868] - Minfeng Chen, Xueping Lei, Changzheng Shi, Maohua Huang, Xiaobo Li, Baojian Wu, Zhengqiu Li, Weili Han, Bin Du, Jianyang Hu, Qiulin Nie, Weiqian Mai, Nan Ma, Nanhui Xu, Xinyi Zhang, Chunlin Fan, Aihua Hong, Minghan Xia, Liangping Luo, Ande Ma, Hongsheng Li, Qiang Yu, Heru Chen, Dongmei Zhang, Wencai Ye. Pericyte-targeting prodrug overcomes tumor resistance to vascular disrupting agents.
The Journal of clinical investigation.
2017 Oct; 127(10):3689-3701. doi:
10.1172/jci94258. [PMID: 28846068] - Kewen He, Xinzhao Wang, Xiyun Guan, Qian Yu, Qinghua Ma, Zhaoyun Liu, Zhiyong Yu. Vinorelbine Plus Gemcitabine or Cisplatin as First-line Treatment of HER2-negative Advanced Breast Cancer.
Anticancer research.
2017 10; 37(10):5647-5653. doi:
10.21873/anticanres.12000. [PMID: 28982882] - Ezequiel Cordova, Laura Morganti, Andrea Odzak, Florencia Arcondo, Mariana Silva, Marcelo Zylberman, Claudia Rodriguez. Severe hypokalemia due to a possible drug-drug interaction between vinblastine and antiretrovirals in a HIV-infected patient with Hodgkin's lymphoma.
International journal of STD & AIDS.
2017 10; 28(12):1259-1262. doi:
10.1177/0956462417703026. [PMID: 28403692] - Esmaeel Haghshenas, Tayyebeh Madrakian, Abbas Afkhami, Haidar Saify Nabiabad. A label-free electrochemical biosensor based on tubulin immobilized on gold nanoparticle/glassy carbon electrode for the determination of vinblastine.
Analytical and bioanalytical chemistry.
2017 Sep; 409(22):5269-5278. doi:
10.1007/s00216-017-0471-y. [PMID: 28667386] - Yuqian Zhang, Yupeng Sun, Xiyan Mu, Lin Yuan, Qiao Wang, Lantong Zhang. Identification of metabolites of vindoline in rats using ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Aug; 1060(?):126-137. doi:
10.1016/j.jchromb.2017.05.038. [PMID: 28609700] - Jun-Jie Ma, Hui-Ping Liu. Efficacy of Aidi Injection () on overexpression of P-glycoprotein induced by vinorelbine and cisplatin regimen in patients with non-small cell lung cancer.
Chinese journal of integrative medicine.
2017 Jul; 23(7):504-509. doi:
10.1007/s11655-016-2511-4. [PMID: 27484766] - Farah Wahida Ayob, Khanom Simarani, Nurhayati Zainal Abidin, Jamaludin Mohamad. First report on a novel Nigrospora sphaerica isolated from Catharanthus roseus plant with anticarcinogenic properties.
Microbial biotechnology.
2017 07; 10(4):926-932. doi:
10.1111/1751-7915.12603. [PMID: 28612376] - Jesús Muñoz-Rojas. Importance of producing economic compounds to combat cancer.
Microbial biotechnology.
2017 07; 10(4):683-684. doi:
10.1111/1751-7915.12491. [PMID: 28127869] - Jia-Shuan Wu, Li-Min Mu, Ying-Zi Bu, Lei Liu, Yan Yan, Ying-Jie Hu, Jing Bai, Jing-Ying Zhang, Weiyue Lu, Wan-Liang Lu. C-type natriuretic peptide-modified lipid vesicles: fabrication and use for the treatment of brain glioma.
Oncotarget.
2017 Jun; 8(25):40906-40921. doi:
10.18632/oncotarget.16641. [PMID: 28402948] - Li-Min Mu, Ying-Zi Bu, Lei Liu, Hong-Jun Xie, Rui-Jun Ju, Jia-Shuan Wu, Fan Zeng, Yao Zhao, Jing-Ying Zhang, Wan-Liang Lu. Lipid vesicles containing transferrin receptor binding peptide TfR-T12 and octa-arginine conjugate stearyl-R8 efficiently treat brain glioma along with glioma stem cells.
Scientific reports.
2017 06; 7(1):3487. doi:
10.1038/s41598-017-03805-7. [PMID: 28615716] - Daniel G Rosas-Ramírez, Mabel Fragoso-Serrano, Sonia Escandón-Rivera, Alba L Vargas-Ramírez, Juan P Reyes-Grajeda, Manuel Soriano-García. Resistance-modifying Activity in Vinblastine-resistant Human Breast Cancer Cells by Oligosaccharides Obtained from Mucilage of Chia Seeds (Salvia hispanica).
Phytotherapy research : PTR.
2017 Jun; 31(6):906-914. doi:
10.1002/ptr.5815. [PMID: 28425219] - Mavis Jiarong Li, Abhinav Nath, William M Atkins. Differential Coupling of Binding, ATP Hydrolysis, and Transport of Fluorescent Probes with P-Glycoprotein in Lipid Nanodiscs.
Biochemistry.
2017 05; 56(19):2506-2517. doi:
10.1021/acs.biochem.6b01245. [PMID: 28441502] - Hongyang Li, Li Sun, Hang Li, Xiaodan Lv, Herve Semukunzi, Ruiming Li, Jun Yu, Shengtao Yuan, Sensen Lin. DT-13, a saponin monomer 13 of the Dwarf lilyturf tuber, synergized with vinorelbine to induce mitotic arrest via activation of ERK signaling pathway in NCI-H1299 cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2017 May; 89(?):1277-1285. doi:
10.1016/j.biopha.2017.02.104. [PMID: 28320095] - Lijing Jiao, Changsheng Dong, Jiaxiang Liu, Zhiwei Chen, Lei Zhang, Jianfang Xu, Xiaoyong Shen, Jiaming Che, Yi Yang, Hai Huang, Hegen Li, Jianli Sun, Yi Jiang, Zhujun Mao, Peiqi Chen, Yabin Gong, Xiaolin Jin, Ling Xu. Effects of Chinese Medicine as Adjunct Medication for Adjuvant Chemotherapy Treatments of Non-Small Cell Lung Cancer Patients.
Scientific reports.
2017 04; 7(?):46524. doi:
10.1038/srep46524. [PMID: 28436479] - Jakob Skalleberg, Olesya Solheim, Sophie D Fosså, Milada Cvancarova Småstuen, Terje Osnes, Per Ole M Gundersen, Marie Bunne. Long-term ototoxicity in women after cisplatin treatment for ovarian germ cell cancer.
Gynecologic oncology.
2017 04; 145(1):148-153. doi:
10.1016/j.ygyno.2017.02.006. [PMID: 28202195] - Bjørg Sjøblom, Jūratė Šaltytė Benth, Bjørn H Grønberg, Vickie E Baracos, Michael B Sawyer, Øystein Fløtten, Marianne J Hjermstad, Nina Aass, Marit Jordhøy. Drug Dose Per Kilogram Lean Body Mass Predicts Hematologic Toxicity From Carboplatin-Doublet Chemotherapy in Advanced Non-Small-Cell Lung Cancer.
Clinical lung cancer.
2017 03; 18(2):e129-e136. doi:
10.1016/j.cllc.2016.09.008. [PMID: 27825639] - Shinsuke Hamada, Keiichi Ito, Taiki Kanbara, Yujiro Tsujita, Hidehiko Yoshii, Shinsuke Tasaki, Junichi Asakuma, Akio Horiguchi, Tomohiko Asano. [A CASE OF METASTATIC BLADDER UROTHELIAL CARCINOMA WHOSE DISEASE WAS CONTROLLED FOR A RELATIVE LONG PERIOD BY MULTIDISCIPLINARY TREATMENT INCLUDING RADIATION TO A LUNG METASTASIS AND MULTIPLE COURSES OF CHEMOTHERAPY].
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology.
2017; 108(1):35-40. doi:
10.5980/jpnjurol.108.35. [PMID: 29367507] - Rituparna Mittra, Megan Pavy, Nanditha Subramanian, Anthony M George, Megan L O'Mara, Ian D Kerr, Richard Callaghan. Location of contact residues in pharmacologically distinct drug binding sites on P-glycoprotein.
Biochemical pharmacology.
2017 Jan; 123(?):19-28. doi:
10.1016/j.bcp.2016.10.002. [PMID: 27729218] - Sara Cruz-Morales, Jhon Castañeda-Gómez, Daniel Rosas-Ramírez, Mabel Fragoso-Serrano, Gabriela Figueroa-González, Argelia Lorence, Rogelio Pereda-Miranda. Resin Glycosides from Ipomoea alba Seeds as Potential Chemosensitizers in Breast Carcinoma Cells.
Journal of natural products.
2016 Dec; 79(12):3093-3104. doi:
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