Salicyluric acid (BioDeep_00000001399)

 

Secondary id: BioDeep_00000229649, BioDeep_00000265249, BioDeep_00000405379

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite


代谢物信息卡片


2-[(2-hydroxyphenyl)formamido]acetic acid

化学式: C9H9NO4 (195.0531554)
中文名称: 2-羟基马尿酸, 水杨尿酸
谱图信息: 最多检出来源 Homo sapiens(blood) 0.51%

Reviewed

Last reviewed on 2024-09-13.

Cite this Page

Salicyluric acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/salicyluric_acid (retrieved 2024-09-17) (BioDeep RN: BioDeep_00000001399). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=CC=C(C(=C1)C(=O)NCC(=O)O)O
InChI: InChI=1S/C9H9NO4/c11-7-4-2-1-3-6(7)9(14)10-5-8(12)13/h1-4,11H,5H2,(H,10,14)(H,12,13)

描述信息

Salicyluric acid is an aryl glycine conjugate formed by the body to eliminate excess salicylates, including aspirin. Aspirin is rapidly hydrolysed to salicylic acid which is further metabolized to various compounds, including salicyluric acid (SU) as well as various acyl and phenolic glucuronides, and hydroxylated metabolites. SU is the major metabolite of SA excreted in urine and it is present in the urine of people who have not taken salicylate drugs, although it has no anti-inflammatory effects in humans or in animals. More salicyluric acid (SU) is excreted in the urine of vegetarians than in non-vegetarians, primarily because fruits and vegetables are important sources of dietary salicylates. However, significantly less (10-15X) SU is excreted by vegetarians than individuals taking low-dose aspirin (PMID: 12944546). The induction of the salicyluric acid formation is one of the saturable pathways of salicylate elimination. The formation of the methyl ester of salicyluric acid is observed during the quantitation of salicyluric acid and other salicylate metabolites in urine by high-pressure liquid chromatography. This methyl ester formation causes artificially low values for salicyluric acid and high values for salicylic acid. (PMID: 6101164, 6857178). Salicyluric acid has been found to be a microbial metabolite.
Constituent of milk
KEIO_ID H028
Salicyluric acid is an endogenous metabolite.

同义名列表

33 个代谢物同义名

2-[(2-hydroxyphenyl)formamido]acetic acid; 2-[(2-Hydroxybenzoyl)amino]acetic acid; ((2-Hydroxybenzoyl)amino)acetic acid; [(2-Hydroxybenzoyl)amino]acetic acid; 2-Hydroxybenzoylaminoacetic acid; [(2-Hydroxybenzoyl)amino]acetate; Salicylurate, monosodium salt; Glycine,N-(2-hydroxybenzoyl)-; N-(2-Hydroxybenzoyl)-glycine; 2-Hydroxybenzoylaminoacetate; N-(O-Hydroxybenzoyl)glycine; N-(2-Hydroxybenzoyl)glycine; Ortho-hydroxyhippuric acid; N-O-Hydroxybenzoylglycine; (2-Hydroxybenzoyl)glycine; O-Hydroxy-hippuric acid; 2-Hydroxybenzoylglycine; 2-Hydroxyhippuric acid; o-Hydroxyhippuric acid; Ortho-hydroxyhippurate; O-Hydroxyhippic acid; O-Hydroxy-hippurate; N-Salicyloylglycine; O-Hydroxyhippurate; 2-Hydroxyhippurate; Salicyloylglycine; Salicyluric acid; O-Hydroxyhippate; Salicylic Acid; Salicylglycine; Salicylurate; Salicylate; Salicyluric acid



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(3)

BioCyc(0)

PlantCyc(0)

代谢反应

54 个相关的代谢反应过程信息。

Reactome(54)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

5 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

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