propachlor (BioDeep_00000001175)
代谢物信息卡片
propachlor
化学式: C11H14ClNO (211.0764)
中文名称: 甲醇中毒草胺溶液
谱图信息:
最多检出来源 Viridiplantae(plant) 3.45%
分子结构信息
SMILES: CC(C)N(C(=O)CCl)C1=CC=CC=C1
InChI: InChI=1S/C11H14ClNO/c1-9(2)13(11(14)8-12)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3
描述信息
D010575 - Pesticides > D006540 - Herbicides
D016573 - Agrochemicals
CONFIDENCE standard compound; EAWAG_UCHEM_ID 708
CONFIDENCE standard compound; INTERNAL_ID 3622
CONFIDENCE standard compound; INTERNAL_ID 8397
同义名列表
2 个代谢物同义名
数据库引用编号
28 个数据库交叉引用编号
- ChEBI: CHEBI:19503
- KEGG: C18759
- PubChem: 4931
- Metlin: METLIN44545
- ChEMBL: CHEMBL1394829
- CAS: 1918-16-7
- MoNA: EA070814
- MoNA: EA070813
- MoNA: EA070812
- MoNA: EA070811
- MoNA: EA070810
- MoNA: EA070809
- MoNA: EA070808
- MoNA: EA070807
- MoNA: EA070806
- MoNA: EA070805
- MoNA: EA070804
- MoNA: EA070803
- MoNA: EA070802
- MoNA: EA070801
- MoNA: AU362203
- MoNA: AU362202
- MoNA: AU362204
- MoNA: AU362201
- MoNA: SM839705
- PMhub: MS000000078
- PubChem: 124489433
- KNApSAcK: 19503
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- G L Larsen, V J Feil, J E Bakke. Metabolism of N-isopropylacetanilide in rat.
Xenobiotica; the fate of foreign compounds in biological systems.
2000 Dec; 30(12):1153-7. doi:
10.1080/00498250010021693. [PMID: 11307971] - B Bordás, T Kömíves, Z Szántó, A Lopata. Comparative three-dimensional quantitative structure-activity relationship study of safeners and herbicides.
Journal of agricultural and food chemistry.
2000 Mar; 48(3):926-31. doi:
10.1021/jf990395+. [PMID: 10725176] - K L Davison, G L Larsen, V J Feil. Comparative metabolism and elimination of acetanilide compounds by rat.
Xenobiotica; the fate of foreign compounds in biological systems.
1994 Oct; 24(10):1003-12. doi:
10.3109/00498259409043297. [PMID: 7900406] - J E Bakke, G L Larsen, K L Davison. Effect of AT-125 on the metabolism of propachlor and the glutathione conjugates of propachlor and bromobenzene in rat.
Xenobiotica; the fate of foreign compounds in biological systems.
1994 Sep; 24(9):909-19. doi:
10.3109/00498259409043289. [PMID: 7810172] - K L Davison, G L Larsen. Propachlor-S-cysteine: a major circulating metabolite in the calf, pig and rat after administration of propachlor.
Xenobiotica; the fate of foreign compounds in biological systems.
1993 Mar; 23(3):297-305. doi:
10.3109/00498259309059383. [PMID: 8498092] - K L Davison. Propachlor-S-glutathione metabolism by kidneys and ureters of calves.
Journal of animal science.
1991 Mar; 69(3):1116-21. doi:
10.2527/1991.6931116x. [PMID: 2061243] - K L Davison, J E Bakke. Elimination of 14C by calves, pigs and rats renally perfused with radiolabelled dichlorovinyl or acetamide substrates.
Toxicology letters.
1990 Sep; 53(1-2):135-7. doi:
10.1016/0378-4274(90)90108-x. [PMID: 2219153] - J E Bakke, K L Davison, G L Larsen. Evidence for the absence of cysteine S-conjugate N-acetyltransferase activity in the metabolism of propachlor, naphthalene, and dichlobanil in calves.
Xenobiotica; the fate of foreign compounds in biological systems.
1990 Aug; 20(8):801-7. doi:
10.3109/00498259009046894. [PMID: 2219963] - K L Davison, J E Bakke, G L Larsen. Metabolism of the glutathione conjugate of propachlor by in situ perfused kidneys and livers of rats.
Xenobiotica; the fate of foreign compounds in biological systems.
1990 Apr; 20(4):375-83. doi:
10.3109/00498259009046854. [PMID: 2346034] - K L Davison, J E Bakke, G L Larsen. A kidney perfusion method for metabolism studies with chickens using propachlor as a model.
Xenobiotica; the fate of foreign compounds in biological systems.
1988 Mar; 18(3):323-9. doi:
10.3109/00498258809041668. [PMID: 3381543] - P W Aschbacher, C B Struble. Evidence for involvement of non-biliary excretion into the intestines in the formation of methylsulphonyl-containing metabolites of 2-chloro-N-isopropylacetanilide (propachlor) by swine and rats.
Xenobiotica; the fate of foreign compounds in biological systems.
1987 Sep; 17(9):1047-55. doi:
10.3109/00498258709044203. [PMID: 3687061] - S Zilkah, M Osband, R McCaffrey, H Shapiro. The effect of the plant cell inhibitor propachlor (alpha-chloro-N-isopropyl-acetanilide) on the cell cycle of L1210 cells as evaluated by flow cytometry.
Life sciences.
1985 Jun; 36(22):2111-5. doi:
10.1016/0024-3205(85)90307-8. [PMID: 3999917] - J J Rafter, J A Gustafsson, J E Bakke, G L Larsen, K E Norin, B E Gustafsson. Studies on the re-establishment of the intestinal microflora in germ-free rats with special reference to the metabolism of N-isopropyl-alpha-chloroacetanilide (propachlor).
Xenobiotica; the fate of foreign compounds in biological systems.
1983 Mar; 13(3):171-8. doi:
10.3109/00498258309052251. [PMID: 6613163] - S Novakova, A Strateva. [Toxicologic characteristics of several pesticides and standards for them in water].
Problemi na khigienata.
1983; 8(?):116-20. doi:
. [PMID: 6672816] - J E Bakke, J Rafter, G L Larsen, J A Gustafsson, B E Gustafsson. Enterohepatic circulation of the mercapturic acid and cysteine conjugates of propachlor.
Drug metabolism and disposition: the biological fate of chemicals.
1981 Nov; 9(6):525-8. doi:
. [PMID: 6120810] - G L Larsen, J E Bakke. Enterohepatic circulation in formation of propachlor (2-chloro-N-isopropylacetanilide) metabolites in the rat.
Xenobiotica; the fate of foreign compounds in biological systems.
1981 Jul; 11(7):473-80. doi:
10.3109/00498258109045857. [PMID: 7293235] - V J Feil, J E Bakke, G L Larsen, B E Gustafsson. A new metabolite of propachlor isolated from germfree rat excreta.
Biomedical mass spectrometry.
1981 Jan; 8(1):1-4. doi:
10.1002/bms.1200080102. [PMID: 7272464] - A Baĭnova, T Burkova, A Mikhaĭlova. [Comparative study of the intermittent and continuous action of the herbicide, Ramrod].
Problemi na khigienata.
1980; 5(?):68-74. doi:
NULL. [PMID: 7443664] - J M Gentile, E D Wagner, M J Plewa. The detection of weak recombinogenic activities in the herbicides alachlor and propachlor using a plant-activation bioassay.
Mutation research.
1977; 48(1):113-6. doi:
10.1016/0027-5107(77)90196-8. [PMID: 834196] - J E Bakke, V J Feil, C E Price. Replacement of a chlorine with a methylsulfonyl group in the metabolism of propachlor (2-chloro-N-isopropylacetanilide).
Biomedical mass spectrometry.
1976 Oct; 3(5):226-9. doi:
10.1002/bms.1200030506. [PMID: 974237]
