Aplysin (BioDeep_00000011573)

   


代谢物信息卡片


[3S-(3alpha,3abeta,8bbeta)]-7-Bromo-2,3,3a,8b-tetrahydro-3,3a,6,8b-tetramethyl-1H-cyclopenta[b]benzofuran

化学式: C15H19BrO (294.0619)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c1c(c(cc2c1[C@]1([C@@](O2)([C@H](CC1)C)C)C)C)Br
InChI: InChI=1S/C15H19BrO/c1-9-7-13-11(8-12(9)16)14(3)6-5-10(2)15(14,4)17-13/h7-8,10H,5-6H2,1-4H3/t10-,14-,15-/m0/s1



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 15 BCL2, BCL2L1, BIRC5, CASP3, CASP9, CCND1, CDKN1A, CDKN1B, CYP2E1, MAPK14, MYD88, PIK3CA, SLC11A2, TLR4, TRIM69
Golgi apparatus, trans-Golgi network membrane 1 SLC11A2
Peripheral membrane protein 3 AOC1, CYP2E1, GORASP1
Endosome membrane 3 MYD88, SLC11A2, TLR4
Endoplasmic reticulum membrane 3 BCL2, CYP2E1, HSP90B1
Mitochondrion membrane 1 BCL2L1
Nucleus 13 BCL2, BIRC5, CASP3, CASP9, CCND1, CDKN1A, CDKN1B, FABP2, HSP90B1, MAPK14, MYD88, SLC11A2, TRIM69
cytosol 14 BCL2, BCL2L1, BIRC5, CASP3, CASP9, CCND1, CDKN1A, CDKN1B, FABP2, HSP90B1, MAPK14, MYD88, PIK3CA, TRIM69
nuclear body 1 CDKN1A
trans-Golgi network 1 SLC11A2
centrosome 3 BCL2L1, CCND1, TRIM69
nucleoplasm 6 BIRC5, CASP3, CCND1, CDKN1A, CDKN1B, MAPK14
Cell membrane 3 AOC1, SLC11A2, TLR4
Cytoplasmic side 2 BCL2L1, GORASP1
lamellipodium 1 PIK3CA
Early endosome membrane 1 SLC11A2
Multi-pass membrane protein 1 SLC11A2
Golgi apparatus membrane 1 GORASP1
cell surface 3 MYD88, SLC11A2, TLR4
glutamatergic synapse 2 CASP3, MAPK14
Golgi apparatus 2 GORASP1, SLC11A2
Golgi membrane 1 GORASP1
lysosomal membrane 1 SLC11A2
mitochondrial inner membrane 2 BCL2L1, CYP2E1
neuronal cell body 1 CASP3
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 1 BCL2L1
Lysosome 1 SLC11A2
endosome 1 CDKN1B
plasma membrane 5 AOC1, MYD88, PIK3CA, SLC11A2, TLR4
synaptic vesicle membrane 1 BCL2L1
Membrane 4 BCL2, HSP90B1, SLC11A2, TLR4
apical plasma membrane 1 SLC11A2
extracellular exosome 2 AOC1, HSP90B1
Lysosome membrane 1 SLC11A2
endoplasmic reticulum 3 BCL2, BCL2L1, HSP90B1
extracellular space 2 AOC1, IL10
perinuclear region of cytoplasm 5 CDKN1A, HSP90B1, PIK3CA, SLC11A2, TLR4
bicellular tight junction 2 AOC1, CCND1
intercalated disc 1 PIK3CA
mitochondrion 5 BCL2, BCL2L1, CASP9, MAPK14, SLC11A2
protein-containing complex 7 BCL2, BIRC5, CASP9, CDKN1A, CDKN1B, HSP90B1, MYD88
intracellular membrane-bounded organelle 2 CDKN1B, CYP2E1
Microsome membrane 1 CYP2E1
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 TLR4
Secreted 1 IL10
extracellular region 4 AOC1, HSP90B1, IL10, MAPK14
Mitochondrion outer membrane 3 BCL2, BCL2L1, SLC11A2
Single-pass membrane protein 2 BCL2, BCL2L1
mitochondrial outer membrane 3 BCL2, BCL2L1, SLC11A2
basal part of cell 1 SLC11A2
Mitochondrion matrix 1 BCL2L1
mitochondrial matrix 1 BCL2L1
Extracellular side 1 AOC1
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 2 BCL2L1, TRIM69
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 BCL2L1
Nucleus membrane 3 BCL2, BCL2L1, CCND1
Bcl-2 family protein complex 2 BCL2, BCL2L1
nuclear membrane 3 BCL2, BCL2L1, CCND1
external side of plasma membrane 1 TLR4
Extracellular vesicle 1 SLC11A2
cytoplasmic vesicle 1 SLC11A2
microtubule cytoskeleton 1 BIRC5
nucleolus 1 CDKN1A
midbody 2 BIRC5, HSP90B1
Early endosome 2 SLC11A2, TLR4
apical part of cell 1 SLC11A2
recycling endosome 1 SLC11A2
Apical cell membrane 1 SLC11A2
Mitochondrion inner membrane 1 CYP2E1
pore complex 1 BCL2
Cytoplasm, cytoskeleton, spindle 1 BIRC5
focal adhesion 1 HSP90B1
microtubule 1 BIRC5
spindle 1 BIRC5
cis-Golgi network 1 GORASP1
Peroxisome 1 AOC1
collagen-containing extracellular matrix 1 HSP90B1
nuclear speck 2 MAPK14, TRIM69
interphase microtubule organizing center 1 BIRC5
Cell projection, ruffle 1 TLR4
Late endosome 1 SLC11A2
ruffle 1 TLR4
receptor complex 1 TLR4
Late endosome membrane 1 SLC11A2
phagocytic cup 1 TLR4
Chromosome 1 BIRC5
centriole 1 BIRC5
Secreted, extracellular space 1 AOC1
brush border membrane 1 SLC11A2
spindle pole 1 MAPK14
nuclear chromosome 1 BIRC5
Recycling endosome membrane 1 SLC11A2
microvillus 1 FABP2
Chromosome, centromere 1 BIRC5
Chromosome, centromere, kinetochore 1 BIRC5
Melanosome 1 HSP90B1
Nucleus speckle 1 TRIM69
myelin sheath 1 BCL2
sperm plasma membrane 1 HSP90B1
lipopolysaccharide receptor complex 1 TLR4
ficolin-1-rich granule lumen 1 MAPK14
secretory granule lumen 1 MAPK14
endoplasmic reticulum lumen 1 HSP90B1
transcription repressor complex 1 CCND1
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
specific granule lumen 1 AOC1
kinetochore 1 BIRC5
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 GORASP1
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
apoptosome 1 CASP9
chromosome, centromeric region 1 BIRC5
Sarcoplasmic reticulum lumen 1 HSP90B1
chromosome passenger complex 1 BIRC5
Vacuole 1 SLC11A2
extrinsic component of cytoplasmic side of plasma membrane 1 MYD88
cytoplasmic microtubule 1 BIRC5
spindle microtubule 1 BIRC5
survivin complex 1 BIRC5
death-inducing signaling complex 1 CASP3
extrinsic component of plasma membrane 1 MYD88
[Isoform 3]: Cell membrane 1 SLC11A2
cyclin-dependent protein kinase holoenzyme complex 2 CCND1, CDKN1A
endocytic vesicle lumen 1 HSP90B1
Extracellular vesicle membrane 1 SLC11A2
apical cortex 1 FABP2
endoplasmic reticulum chaperone complex 1 HSP90B1
BAD-BCL-2 complex 1 BCL2
cyclin D1-CDK4 complex 1 CCND1
PCNA-p21 complex 1 CDKN1A
cyclin D1-CDK6 complex 1 CCND1
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
Cul4A-RING E3 ubiquitin ligase complex 1 CDKN1B
[Isoform 1]: Early endosome membrane 1 SLC11A2
[Isoform 2]: Late endosome membrane 1 SLC11A2
paraferritin complex 1 SLC11A2
caspase complex 1 CASP9
[Isoform Bcl-X(L)]: Mitochondrion inner membrane 1 BCL2L1


文献列表

  • Na Ge, Hui Liang, Yuan-Yuan Zhao, Ying Liu, An-Jing Gong, Wen-Long Zhang. Aplysin Protects Against Alcohol-Induced Liver Injury Via Alleviating Oxidative Damage and Modulating Endogenous Apoptosis-Related Genes Expression in Rats. Journal of food science. 2018 Oct; 83(10):2612-2621. doi: 10.1111/1750-3841.14320. [PMID: 30192013]
  • Yan Ma, Ruiying Li, Ying Liu, Man Liu, Hui Liang. Protective Effect of Aplysin Supplementation on Intestinal Permeability and Microbiota in Rats Treated with Ethanol and Iron. Nutrients. 2018 May; 10(6):. doi: 10.3390/nu10060681. [PMID: 29861488]
  • Meilan Xue, Ying Liu, Rui Lyu, Na Ge, Man Liu, Yan Ma, Hui Liang. Protective effect of aplysin on liver tissue and the gut microbiota in alcohol-fed rats. PloS one. 2017; 12(6):e0178684. doi: 10.1371/journal.pone.0178684. [PMID: 28622357]
  • Na Ge, Hui Liang, Ying Liu, Ai-guo Ma, Lei Han. Protective effect of Aplysin on hepatic injury in ethanol-treated rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2013 Dec; 62(?):361-72. doi: 10.1016/j.fct.2013.08.071. [PMID: 24001440]