Carthamin (BioDeep_00000011491)
Secondary id: BioDeep_00001869708
human metabolite Endogenous
代谢物信息卡片
(2E)-5,6-dihydroxy-4-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-({2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1-yl}methylidene)-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohex-4-ene-1,3-dione
化学式: C43H42O22 (910.2168)
中文名称: 红花黄
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=CC=C1C=CC(=O)C2=C(C(C(=C(C2=O)C=C3C(=O)C(=C(C(C3=O)(C4C(C(C(C(O4)CO)O)O)O)O)O)C(=O)C=CC5=CC=C(C=C5)O)O)(C6C(C(C(C(O6)CO)O)O)O)O)O)O
InChI: InChI=1S/C43H42O22/c44-14-24-30(52)32(54)34(56)40(64-24)42(62)36(58)20(28(50)26(38(42)60)22(48)11-5-16-1-7-18(46)8-2-16)13-21-29(51)27(23(49)12-6-17-3-9-19(47)10-4-17)39(61)43(63,37(21)59)41-35(57)33(55)31(53)25(15-45)65-41/h1-13,24-25,30-35,40-41,44-47,52-58,60-63H,14-15H2/b11-5+,12-6+,21-13+
描述信息
Carthamin is found in fats and oils. Red pigment of flower petals of Carthamus tinctorius (safflower) Carthamin is a natural red pigment derived from safflower (Carthamus tinctorius), earlier known as carthamine. It is used as a dye and a food coloring. As a food additive, it is known as Natural Red 26
Red pigment of flower petals of Carthamus tinctorius (safflower)
同义名列表
6 个代谢物同义名
(2E)-5,6-dihydroxy-4-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-({2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1-yl}methylidene)-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohex-4-ene-1,3-dione; C.I. natural red 26; Safflower yellow; Carthamine; Carthamin; Carthamin
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:80810
- KEGG: C16941
- PubChem: 137185914
- PubChem: 135565560
- PubChem: 139597671
- HMDB: HMDB0033898
- Metlin: METLIN71447
- Wikipedia: Carthamin
- KNApSAcK: C00006339
- foodb: FDB012093
- chemspider: 35013673
- CAS: 36338-96-2
- PMhub: MS000025498
- PubChem: 96023430
- NIKKAJI: J208.211J
- KNApSAcK: 80810
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
- 4222 - Carthamus tinctorius:
- 4222 - Carthamus tinctorius: 10.3390/MOLECULES181215220
- 9606 - Homo sapiens: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xiaorui Lyu, Kemin Yan, Hanyuan Xu, Huijuan Zhu, Hui Pan, Linjie Wang, Hongbo Yang, Fengying Gong. Intragastric safflower yellow and its main component HSYA improve leptin sensitivity before body weight change in diet-induced obese mice.
Naunyn-Schmiedeberg's archives of pharmacology.
2022 05; 395(5):579-591. doi:
10.1007/s00210-022-02220-8. [PMID: 35201390] - Toshiyuki Waki, Miho Terashita, Naoki Fujita, Keishi Fukuda, Mikiya Kato, Takashi Negishi, Hiromi Uchida, Yuichi Aoki, Seiji Takahashi, Toru Nakayama. Identification of the Genes Coding for Carthamin Synthase, Peroxidase Homologs that Catalyze the Final Enzymatic Step of Red Pigmentation in Safflower (Carthamus tinctorius L.).
Plant & cell physiology.
2021 Dec; 62(10):1528-1541. doi:
10.1093/pcp/pcab122. [PMID: 34343331] - Shiro Suzuki. Carthamin Synthase Provides New Insight into Traditional 'Beni' Red Pigment Production from Safflowers.
Plant & cell physiology.
2021 12; 62(10):1506-1508. doi:
10.1093/pcp/pcab162. [PMID: 34746959] - Zong-Jin Pu, Shuo Zhang, Yu-Ping Tang, Xu-Qin Shi, Hui-Juan Tao, Hui Yan, Jia-Qian Chen, Shi-Jun Yue, Yan-Yan Chen, Zhen-Hua Zhu, Gui-Sheng Zhou, Shu-Lan Su, Jin-Ao Duan. Study on changes in pigment composition during the blooming period of safflower based on plant metabolomics and semi-quantitative analysis.
Journal of separation science.
2021 Nov; 44(22):4082-4091. doi:
10.1002/jssc.202100439. [PMID: 34514725] - Alexei Baerle, Alexandra Savcenco, Pavel Tatarov, Florinela Fetea, Raisa Ivanova, Oxana Radu. Stability limits of a red Carthamin-cellulose complex as a potential food colourant.
Food & function.
2021 Sep; 12(17):8037-8043. doi:
10.1039/d1fo01376a. [PMID: 34279018] - Huihui Guo, Lili Zhu, Pingping Tang, Dong Chen, Yancai Li, Jianbing Li, Chao Bao. Carthamin yellow improves cerebral ischemia‑reperfusion injury by attenuating inflammation and ferroptosis in rats.
International journal of molecular medicine.
2021 04; 47(4):. doi:
10.3892/ijmm.2021.4885. [PMID: 33576458] - Chao Du, Jiawei Hou, Chunhui Wang, Mengyu Zhang, Yanjie Zheng, Guang Yang, Yanli Hu. Effects of safflower yellow on cholesterol levels in serum and brain tissue of APP/PS1 mice.
Metabolic brain disease.
2021 04; 36(4):557-569. doi:
10.1007/s11011-021-00680-0. [PMID: 33550459] - Song Guo, Yubin Xu, Guirong Chen. [Screening and identification of potential targets of carthamin against sepsis].
Zhonghua wei zhong bing ji jiu yi xue.
2021 Jan; 33(1):23-27. doi:
10.3760/cma.j.cn121430-20200508-00368. [PMID: 33565395] - Kemin Yan, Xiangqing Wang, Huijuan Zhu, Hui Pan, Linjie Wang, Hongbo Yang, Meijuan Liu, Ming Jin, Baoxia Zang, Fengying Gong. Safflower yellow improves insulin sensitivity in high-fat diet-induced obese mice by promoting peroxisome proliferator-activated receptor-γ2 expression in subcutaneous adipose tissue.
Journal of diabetes investigation.
2020 Nov; 11(6):1457-1469. doi:
10.1111/jdi.13285. [PMID: 32356607] - Hai Li, Baotian Kan, Lingli Song, Yufa Liu, Xiangdong Jian. Role of the Hippo signaling pathway in safflower yellow pigment treatment of paraquat-induced pulmonary fibrosis.
The Journal of international medical research.
2020 Sep; 48(9):300060520905425. doi:
10.1177/0300060520905425. [PMID: 32940100] - Yong-Ling Chen, Ben Cai, Wei Zhang, Zhuo-Qi Xie, Wei Huang, Li Pan, Min Lu. [Study on safflower yellow for injection based on cell degranulation and acute anaphylactoid model].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2019 Sep; 44(17):3792-3797. doi:
10.19540/j.cnki.cjcmm.20190522.401. [PMID: 31602955] - Ling-Mei Li, Jian-Hua Fu, Hao Guo, Xiao Han, Lei Li, Gao-Jie Xin, Yu-Wei Zhao, Qiong Zhang, Qiu-Sheng Zheng, Jian-Xun Liu. [Protective effect of safflower yellow injection against rat MIRI by TLR-NF-κB inflammatory pathway].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2019 Jun; 44(12):2566-2571. doi:
10.19540/j.cnki.cjcmm.20190201.001. [PMID: 31359725] - Jiawei He, Shanshan Li, Kailin Xu, Bin Tang, Hongqin Yang, Qing Wang, Hui Li. Binding properties of the natural red dye carthamin with human serum albumin: Surface plasmon resonance, isothermal titration microcalorimetry, and molecular docking analysis.
Food chemistry.
2017 Apr; 221(?):650-656. doi:
10.1016/j.foodchem.2016.11.124. [PMID: 27979254] - L D Bao, Y Wang, X H Ren, R L Ma, H J Lv, B Agula. Hypolipidemic effect of safflower yellow and primary mechanism analysis.
Genetics and molecular research : GMR.
2015 Jun; 14(2):6270-8. doi:
10.4238/2015.june.9.14. [PMID: 26125829] - Yuntao Dai, Robert Verpoorte, Young Hae Choi. Natural deep eutectic solvents providing enhanced stability of natural colorants from safflower (Carthamus tinctorius).
Food chemistry.
2014 Sep; 159(?):116-21. doi:
10.1016/j.foodchem.2014.02.155. [PMID: 24767033] - Nidhal Salem, Kamel Msaada, Salem Elkahoui, Giuseppe Mangano, Sana Azaeiz, Imen Ben Slimen, Sarra Kefi, Giorgio Pintore, Ferid Limam, Brahim Marzouk. Evaluation of antibacterial, antifungal, and antioxidant activities of safflower natural dyes during flowering.
BioMed research international.
2014; 2014(?):762397. doi:
10.1155/2014/762397. [PMID: 25045699] - Daiwei Zhou, Bingbing Liu, Xiaoshan Xiao, Peng Dai, Songmei Ma, Weihua Huang. The effect of safflower yellow on spinal cord ischemia reperfusion injury in rabbits.
Oxidative medicine and cellular longevity.
2013; 2013(?):692302. doi:
10.1155/2013/692302. [PMID: 24381717] - Hai-Xia Li, Shu-Yan Han, Xian-Wei Wang, Xu Ma, Ke Zhang, Li Wang, Zhi-Zhong Ma, Peng-Fei Tu. Effect of the carthamins yellow from Carthamus tinctorius L. on hemorheological disorders of blood stasis in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2009 Aug; 47(8):1797-802. doi:
10.1016/j.fct.2009.04.026. [PMID: 19406191] - Midori Hiramatsu, Tomoko Takahashi, Makiko Komatsu, Toshitaka Kido, Yoshimasa Kasahara. Antioxidant and neuroprotective activities of Mogami-benibana (safflower, Carthamus tinctorius Linne).
Neurochemical research.
2009 Apr; 34(4):795-805. doi:
10.1007/s11064-008-9884-5. [PMID: 19082884] - Yu Jin, Xiu-li Zhang, Hui Shi, Yuan-sheng Xiao, Yan-xiong Ke, Xing-ya Xue, Fei-fang Zhang, Xin-miao Liang. Characterization of C-glycosyl quinochalcones in Carthamus tinctorius L. by ultraperformance liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2008 Apr; 22(8):1275-87. doi:
10.1002/rcm.3468. [PMID: 18383217] - Zhiguo Yu, Xiaoxia Gao, Yunli Zhao, Kaishun Bi. HPLC determination of safflor yellow A and three active isoflavones from TCM Naodesheng in rat plasma and tissues and its application to pharmacokinetic studies.
Biomedical chromatography : BMC.
2007 Jun; 21(6):577-84. doi:
10.1002/bmc.764. [PMID: 17385809] - Yi Li, Zhao-Yang Zhang, Jin-Lan Zhang. Determination of hydroxysafflor yellow A in rat plasma and tissues by high-performance liquid chromatography after oral administration of safflower extract or safflor yellow.
Biomedical chromatography : BMC.
2007 Mar; 21(3):326-34. doi:
10.1002/bmc.769. [PMID: 17221936] - Z Yang, A Wen, Q Mei, Y Jiang, M Zhao, S Zhang. [Pharmacokinetical study of safflor yellow on rat acute model of blood stasis syndrome].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2001 Oct; 24(10):730-2. doi:
NULL. [PMID: 11822287] - M H Cho, T R Hahn. Purification and characterization of precarthamin decarboxylase from the yellow petals of Carthamus tinctorius L.
Archives of biochemistry and biophysics.
2000 Oct; 382(2):238-44. doi:
10.1006/abbi.2000.1984. [PMID: 11068875] - M H Cho, Y S Paik, T R Hahn. Enzymatic conversion of precarthamin to carthamin by a purified enzyme from the yellow petals of safflower.
Journal of agricultural and food chemistry.
2000 Sep; 48(9):3917-21. doi:
10.1021/jf9911038. [PMID: 10995291] - Y Jin, D Xu, W Xu. [Influence of safflower injection on hemorheology of patients of chronic cor pulmonale during acute attack].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2000 Jun; 20(6):430-2. doi:
NULL. [PMID: 11789226] - M R Meselhy, S Kadota, M Hattori, T Namba. Metabolism of safflor yellow B by human intestinal bacteria.
Journal of natural products.
1993 Jan; 56(1):39-45. doi:
10.1021/np50091a006. [PMID: 8450320] - F Liu, Y Wei, X Z Yang, F G Li, J Hu, R F Cheng. [Hypotensive effects of safflower yellow in spontaneously hypertensive rats and influence on plasma renin activity and angiotensin II level].
Yao xue xue bao = Acta pharmaceutica Sinica.
1992; 27(10):785-7. doi:
NULL. [PMID: 1293928] - Z W Lu, F Liu, J Hu, D Bian, F G Li. [Suppressive effects of safflower yellow on immune functions].
Zhongguo yao li xue bao = Acta pharmacologica Sinica.
1991 Nov; 12(6):537-42. doi:
NULL. [PMID: 1840455]
