Isoflavone (BioDeep_00000001083)

 

Secondary id: BioDeep_00000017687, BioDeep_00000268731, BioDeep_00000869527

human metabolite PANOMIX_OTCML-2023 blood metabolite natural product


代谢物信息卡片


3-phenyl-4H-1-benzopyran-4-one

化学式: C15H10O2 (222.0681)
中文名称: 大豆异黄酮
谱图信息: 最多检出来源 Homo sapiens(blood) 24.9%

分子结构信息

SMILES: C1=CC=C(C=C1)C2=COC3=CC=CC=C3C2=O
InChI: InChI=1S/C15H10O2/c16-15-12-8-4-5-9-14(12)17-10-13(15)11-6-2-1-3-7-11/h1-10H

描述信息

Isoflavones are a class of phytochemicals related to the isoflavonoids. Isoflavones are produced almost exclusively by the members of the Fabaceae (i.e., Leguminosae, or bean) family. Soy isoflavones consumption has been related to a lower incidence of breast cancer and other common cancers. [Wikipedia]. Isoflavones is found in soy bean.
Isoflavone, a soy phytoestrogen and a biologically active component, presents in several agriculturally important legumes such as soy, peanut, green peas, chick peas and alfalfa[1][2].
Isoflavone, a soy phytoestrogen and a biologically active component, presents in several agriculturally important legumes such as soy, peanut, green peas, chick peas and alfalfa[1][2].

同义名列表

7 个代谢物同义名

3-phenyl-4H-1-benzopyran-4-one; 3-phenyl-4H-chromen-4-one; Isoflavone skeleton; 3-Phenylchromone; Isoflavones; Isoflavone; isoflavon



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

23 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 15 ABCB1, AKT1, BCL2, BGLAP, CTNNB1, EGFR, MAPK14, MAPK8, MTOR, NFE2L2, PPARG, PTGS2, RELA, TNK1, TP53
Peripheral membrane protein 4 CYP1B1, MTOR, PTGS2, TNK1
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 6 BCL2, CYP1B1, EGFR, HMOX1, MTOR, PTGS2
Nucleus 13 AKT1, BCL2, CTNNB1, EGFR, HMOX1, KLK3, MAPK14, MAPK8, MTOR, NFE2L2, PPARG, RELA, TP53
cytosol 11 AKT1, BCL2, CTNNB1, HMOX1, MAPK14, MAPK8, MTOR, NFE2L2, PPARG, RELA, TP53
dendrite 2 BGLAP, MTOR
phagocytic vesicle 1 MTOR
centrosome 3 CTNNB1, NFE2L2, TP53
nucleoplasm 10 AKT1, CTNNB1, HMOX1, MAPK14, MAPK8, MTOR, NFE2L2, PPARG, RELA, TP53
RNA polymerase II transcription regulator complex 2 NFE2L2, PPARG
Cell membrane 4 ABCB1, AKT1, CTNNB1, EGFR
Cytoplasmic side 2 HMOX1, MTOR
lamellipodium 2 AKT1, CTNNB1
ruffle membrane 1 EGFR
Early endosome membrane 1 EGFR
Multi-pass membrane protein 1 ABCB1
Golgi apparatus membrane 1 MTOR
Synapse 2 CTNNB1, MAPK8
cell cortex 2 AKT1, CTNNB1
cell junction 2 CTNNB1, EGFR
cell surface 2 ABCB1, EGFR
glutamatergic synapse 5 AKT1, CTNNB1, EGFR, MAPK14, RELA
Golgi apparatus 1 NFE2L2
Golgi membrane 3 EGFR, INS, MTOR
lysosomal membrane 1 MTOR
postsynapse 1 AKT1
presynaptic membrane 1 CTNNB1
Cytoplasm, cytosol 1 NFE2L2
Lysosome 1 MTOR
endosome 1 EGFR
plasma membrane 7 ABCB1, AKT1, CTNNB1, EGFR, KLK3, NFE2L2, TNK1
Membrane 10 ABCB1, AKT1, BCL2, CTNNB1, CYP1B1, EGFR, HMOX1, MTOR, TNK1, TP53
apical plasma membrane 2 ABCB1, EGFR
axon 1 MAPK8
basolateral plasma membrane 2 CTNNB1, EGFR
caveola 1 PTGS2
extracellular exosome 3 ABCB1, CTNNB1, KLK3
Lysosome membrane 1 MTOR
endoplasmic reticulum 4 BCL2, HMOX1, PTGS2, TP53
extracellular space 6 BGLAP, EGFR, HMOX1, IL6, INS, KLK3
perinuclear region of cytoplasm 4 CTNNB1, EGFR, HMOX1, PPARG
Schaffer collateral - CA1 synapse 1 CTNNB1
adherens junction 1 CTNNB1
apicolateral plasma membrane 1 CTNNB1
bicellular tight junction 1 CTNNB1
mitochondrion 4 BCL2, CYP1B1, MAPK14, TP53
protein-containing complex 7 AKT1, BCL2, CTNNB1, EGFR, KLK3, PTGS2, TP53
intracellular membrane-bounded organelle 2 CYP1B1, PPARG
Microsome membrane 3 CYP1B1, MTOR, PTGS2
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 1 EGFR
Secreted 3 BGLAP, IL6, INS
extracellular region 5 BGLAP, IL6, INS, KLK3, MAPK14
Mitochondrion outer membrane 2 BCL2, MTOR
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 3 BCL2, HMOX1, MTOR
Mitochondrion matrix 1 TP53
mitochondrial matrix 1 TP53
transcription regulator complex 3 CTNNB1, RELA, TP53
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 2 BCL2, EGFR
perikaryon 1 BGLAP
Z disc 1 CTNNB1
beta-catenin destruction complex 1 CTNNB1
microtubule cytoskeleton 1 AKT1
nucleolus 1 TP53
Wnt signalosome 1 CTNNB1
apical part of cell 1 CTNNB1
cell-cell junction 2 AKT1, CTNNB1
vesicle 2 AKT1, BGLAP
postsynaptic membrane 1 CTNNB1
Apical cell membrane 1 ABCB1
Membrane raft 1 EGFR
pore complex 1 BCL2
Cytoplasm, cytoskeleton 2 CTNNB1, TP53
focal adhesion 2 CTNNB1, EGFR
spindle 1 AKT1
Cell junction, adherens junction 1 CTNNB1
flotillin complex 1 CTNNB1
intracellular vesicle 1 EGFR
Nucleus, PML body 2 MTOR, TP53
PML body 2 MTOR, TP53
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
secretory granule 1 KLK3
fascia adherens 1 CTNNB1
lateral plasma membrane 1 CTNNB1
nuclear speck 1 MAPK14
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
receptor complex 2 EGFR, PPARG
neuron projection 1 PTGS2
ciliary basal body 1 AKT1
chromatin 4 NFE2L2, PPARG, RELA, TP53
mediator complex 1 NFE2L2
cell periphery 1 CTNNB1
Cytoplasm, cytoskeleton, cilium basal body 1 CTNNB1
spindle pole 2 CTNNB1, MAPK14
postsynaptic density, intracellular component 1 CTNNB1
microvillus membrane 1 CTNNB1
site of double-strand break 1 TP53
nuclear envelope 1 MTOR
Endomembrane system 2 CTNNB1, MTOR
endosome lumen 1 INS
euchromatin 1 CTNNB1
germ cell nucleus 1 TP53
replication fork 1 TP53
myelin sheath 1 BCL2
basal plasma membrane 1 EGFR
synaptic membrane 1 EGFR
ficolin-1-rich granule lumen 1 MAPK14
secretory granule lumen 2 INS, MAPK14
Golgi lumen 2 BGLAP, INS
endoplasmic reticulum lumen 4 BGLAP, IL6, INS, PTGS2
nuclear matrix 1 TP53
transcription repressor complex 1 TP53
transport vesicle 1 INS
beta-catenin-TCF complex 1 CTNNB1
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
Single-pass type IV membrane protein 1 HMOX1
presynaptic active zone cytoplasmic component 1 CTNNB1
clathrin-coated endocytic vesicle membrane 1 EGFR
[Isoform 1]: Nucleus 1 TP53
protein-DNA complex 2 CTNNB1, NFE2L2
external side of apical plasma membrane 1 ABCB1
basal dendrite 1 MAPK8
Cytoplasmic vesicle, phagosome 1 MTOR
catenin complex 1 CTNNB1
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
interleukin-6 receptor complex 1 IL6
BAD-BCL-2 complex 1 BCL2
beta-catenin-TCF7L2 complex 1 CTNNB1
NF-kappaB p50/p65 complex 1 RELA
NF-kappaB complex 1 RELA
beta-catenin-ICAT complex 1 CTNNB1
Scrib-APC-beta-catenin complex 1 CTNNB1


文献列表

  • Yingying Lai, Ningning Yang, Donghao Shi, Xianhui Ma, Yingying Huang, Jingzhou Lu, Xuzi Zhang, Hui Zhou, Weiyang Gao, Cong Mao, Long Wang. Puerarin enhances TFEB-mediated autophagy and attenuates ROS-induced pyroptosis after ischemic injury of random-pattern skin flaps. European journal of pharmacology. 2024 Jul; 974(?):176621. doi: 10.1016/j.ejphar.2024.176621. [PMID: 38679118]
  • Rafaela T Privatti, Maria C Capellini, Keila K Aracava, Silvana M P Pugine, Mariza P de Melo, Christianne E C Rodrigues. Saline as solvent and ethanol-based purification process for the extraction of proteins and isoflavones from wet okara. Food chemistry. 2024 Jun; 443(?):138605. doi: 10.1016/j.foodchem.2024.138605. [PMID: 38301555]
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  • Hao-Tian Xu, Qi Zheng, Zong-Guang Tai, Wen-Cheng Jiang, Shao-Qiong Xie, Yue Luo, Xiao-Ya Fei, Ying Luo, Xin Ma, Le Kuai, Ying Zhang, Rui-Ping Wang, Bin Li, Quan-Gang Zhu, Jian-Kun Song. Formononetin attenuates psoriasiform inflammation by regulating interferon signaling pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jun; 128(?):155412. doi: 10.1016/j.phymed.2024.155412. [PMID: 38579666]
  • Yiliang Liu, Yajing Pu, Liyuan Shen, Dan Li, Jingwen Xu, Xiangjiu He, Yihai Wang. Isoflavones isolated from the fruits of Ficus altissima and their anti-proliferative activities. Fitoterapia. 2024 Jun; 175(?):105966. doi: 10.1016/j.fitote.2024.105966. [PMID: 38631600]
  • Guannan Liu, Jie Zhou, Sijin Wu, Shijie Fang, Muhammad Bilal, Chong Xie, Pei Wang, Yongqi Yin, Runqiang Yang. Novel strategy to raise the content of aglycone isoflavones in soymilk and gel: Effect of germination on the physicochemical properties. Food research international (Ottawa, Ont.). 2024 Jun; 186(?):114335. doi: 10.1016/j.foodres.2024.114335. [PMID: 38729717]
  • Guanjie Peng, Yangsi Li, Yiyan Zeng, Bowen Sun, Lanyue Zhang, Qingqing Liu. Effect of glabridin combined with bakuchiol on UVB-induced skin damage and its underlying mechanism: An experimental study. Journal of cosmetic dermatology. 2024 Jun; 23(6):2256-2269. doi: 10.1111/jocd.16259. [PMID: 38497297]
  • Xin Ma, Guoshu Deng, Na Tian, Hao Wang, Hang Zhao, Le Kuai, Ying Luo, Chunjie Gao, Xiaojie Ding, Bin Li, Bin Li. Calycosin enhances Treg differentiation for alleviating skin inflammation in atopic dermatitis. Journal of ethnopharmacology. 2024 May; 326(?):117883. doi: 10.1016/j.jep.2024.117883. [PMID: 38331120]
  • Peipei Zhang, Changyun Yang, Jiao Wang, Pingbo Jiang, Jie Qi, Wenyan Hou, Hao Cheng, Xianzhong Feng, Deyue Yu. Cytochrome GmGLY1 is Involved in the Biosynthesis of Glycitein in Soybean. Journal of agricultural and food chemistry. 2024 May; 72(19):10944-10957. doi: 10.1021/acs.jafc.4c00968. [PMID: 38710505]
  • Hassan Esmaeili, Mohammad Hossein Mirjalili, Akbar Karami, Samad Nejad Ebrahimi. Introducing the glycyrrhizic acid and glabridin rich genotypes from the cultivated Iranian licorice (Glycyrrhiza glabra L.) populations to exploit in production systems. Scientific reports. 2024 05; 14(1):11034. doi: 10.1038/s41598-024-61711-1. [PMID: 38744977]
  • Palash Mandal, David A Mortensen, André F Brito, Anna K Wallingford, Marta R M Lima, Nicholas D Warren, Richard G Smith. Water Stress Influences Phytoestrogen Levels in Red Clover (Trifolium pratense) but Not Kura Clover (T. ambiguum). Journal of agricultural and food chemistry. 2024 May; 72(18):10247-10256. doi: 10.1021/acs.jafc.4c00300. [PMID: 38683760]
  • Fangbing Ren, Yanhui Ma, Kexin Zhang, Youhong Luo, Ruiyan Pan, Jingwen Zhang, Chengxia Kan, Ningning Hou, Fang Han, Xiaodong Sun. Exploring the multi-targeting phytoestrogen potential of Calycosin for cancer treatment: A review. Medicine. 2024 May; 103(18):e38023. doi: 10.1097/md.0000000000038023. [PMID: 38701310]
  • Shengqi Tan, Ying Zhu, Yaqiong Wang, Sijin Wu, Chong Xie, Xin Rui, Pei Wang, Runqiang Yang. Refrigerated storage stimulates isoflavone and γ-aminobutyric acid accumulation in germinated soybeans. Plant physiology and biochemistry : PPB. 2024 May; 210(?):108667. doi: 10.1016/j.plaphy.2024.108667. [PMID: 38678946]
  • Qiuxiang Chen, Juan Wang, Lihua Sun, Bayinsilema Ba, Difei Shen. Mechanism of Astragalus membranaceus (Huangqi, HQ) for treatment of heart failure based on network pharmacology and molecular docking. Journal of cellular and molecular medicine. 2024 May; 28(10):e18331. doi: 10.1111/jcmm.18331. [PMID: 38780500]
  • Huizhen Wei, Mengru Sun, Ruixuan Wang, Hairong Zeng, Bei Zhao, Shenyi Jin. Puerarin mitigated LPS-ATP or HG-primed endothelial cells damage and diabetes-associated cardiovascular disease via ROS-NLRP3 signalling. Journal of cellular and molecular medicine. 2024 May; 28(10):e18239. doi: 10.1111/jcmm.18239. [PMID: 38774996]
  • Tian-Ci Zhang, Yi-Can Lin, Ning-Ning Sun, Shan Liu, Wen-Zhu Hu, Yan Zhao, Xian-Hui Dong, Xiao-Ping He. Icariin, astragaloside a and puerarin mixture attenuates cognitive impairment in APP/PS1 mice via inhibition of ferroptosis-lipid peroxidation. Neurochemistry international. 2024 May; 175(?):105705. doi: 10.1016/j.neuint.2024.105705. [PMID: 38412923]
  • Xue Li, Le Liu, Mei-Xuan Wan, Li-Min Gong, Juan Su, Li Xu. Active Components of Pueraria lobata through the MAPK/ERK Signaling Pathway Alleviate Iron Overload in Alcoholic Liver Disease. Chemistry & biodiversity. 2024 May; 21(5):e202400005. doi: 10.1002/cbdv.202400005. [PMID: 38504590]
  • Ivan Kiganda, Jonathan Bogaerts, Lianne H E Wieske, Tsegaye Deyou, Yoseph Atilaw, Colores Uwamariya, Masum Miah, Joanna Said, Albert Ndakala, Hoseah M Akala, Wouter Herrebout, Edward Trybala, Tomas Bergström, Abiy Yenesew, Mate Erdelyi. Antiviral Rotenoids and Isoflavones Isolated from Millettia oblata ssp. teitensis. Journal of natural products. 2024 Apr; 87(4):1003-1012. doi: 10.1021/acs.jnatprod.3c01288. [PMID: 38579352]
  • Yu Mu, Yalin Yang, Shuang Jiang, Chilu Liu, Yanxing Han, Jiandong Jiang, Yuhong Wang. Benefits of Puerarin on Metabolic Syndrome and Its Associated Cardiovascular Diseases in Rats Fed a High-Fat/High-Sucrose Diet. Nutrients. 2024 Apr; 16(9):. doi: 10.3390/nu16091273. [PMID: 38732519]
  • Shiyan Yue, Yunxiang Liu, Rongrong Zhou, Zhilai Zhan, Liping Kang, Luqi Huang, Yuan Yuan, Tiegui Nan. A Highly Sensitive and Rapid Colloidal Gold Immunoassay for Puerarin Detection. Journal of agricultural and food chemistry. 2024 Apr; 72(15):8817-8822. doi: 10.1021/acs.jafc.4c00644. [PMID: 38578981]
  • Jie Luo, Youde Cai, Dingling Wei, Liping Cao, Qiansong He, Yuanhua Wu. Formononetin alleviates cerebral ischemia-reperfusion injury in rats by targeting the PARP-1/PARG/Iduna signaling pathway. Brain research. 2024 Apr; 1829(?):148845. doi: 10.1016/j.brainres.2024.148845. [PMID: 38452845]
  • Xin Wang, Yufeng Jin, Can Di, Yupeng Zeng, Yuqing Zhou, Yu Chen, Zhijun Pan, Zhongxia Li, Wenhua Ling. Supplementation of Silymarin Alone or in Combination with Salvianolic Acids B and Puerarin Regulates Gut Microbiota and Its Metabolism to Improve High-Fat Diet-Induced NAFLD in Mice. Nutrients. 2024 Apr; 16(8):. doi: 10.3390/nu16081169. [PMID: 38674860]
  • Xiaoxue Fang, Xintian Lan, Ming Zhu, Min He, Mengmeng Sun, Yiming Cao, Difu Zhu, Dean Guo, Haoming Luo. Puerarin Induces Macrophage M2 Polarization to Exert Antinonalcoholic Steatohepatitis Pharmacological Activity via the Activation of Autophagy. Journal of agricultural and food chemistry. 2024 Apr; 72(13):7187-7202. doi: 10.1021/acs.jafc.3c09601. [PMID: 38515289]
  • Mark J Messina, Virginia Messina, Chisato Nagata. Perspective: Observational Studies Involving Low-Soy Intake Populations Have Limited Ability for Providing Insight into the Health Effects of Soybean Isoflavones. Advances in nutrition (Bethesda, Md.). 2024 Apr; 15(4):100210. doi: 10.1016/j.advnut.2024.100210. [PMID: 38484974]
  • Jiyu Weng, Ying Wang, Zekai Tan, Yanghe Yuan, Shiyuan Huang, Zexi Li, Yiming Li, Lanyue Zhang, Zhiyun Du. Glabridin reduces neuroinflammation by modulating inflammatory signals in LPS-induced in vitro and in vivo models. Inflammopharmacology. 2024 Apr; 32(2):1159-1169. doi: 10.1007/s10787-023-01424-5. [PMID: 38372849]
  • Haipeng Chen, Yanmei Lou, Senyi Lin, Xuanjing Tan, Yuting Zheng, Hong Yu, Ruidi Jiang, Yijie Wei, Huijie Huang, Xiaoxiao Qi, Rong Zhang, Zhongqiu Liu, Jinjun Wu. Formononetin, a bioactive isoflavonoid constituent from Astragalus membranaceus (Fisch.) Bunge, ameliorates type 1 diabetes mellitus via activation of Keap1/Nrf2 signaling pathway: An integrated study supported by network pharmacology and experimental validation. Journal of ethnopharmacology. 2024 Mar; 322(?):117576. doi: 10.1016/j.jep.2023.117576. [PMID: 38104880]
  • Jamie Gudyka, Jasmin Ceja-Vega, Katherine Ivanchenko, Wilber Perla, Christopher Poust, Alondra Gamez Hernandez, Colleen Clarke, Shakinah Silverberg, Escarlin Perez, Sunghee Lee. Differential Effects of Soy Isoflavones on the Biophysical Properties of Model Membranes. The journal of physical chemistry. B. 2024 Mar; 128(10):2412-2424. doi: 10.1021/acs.jpcb.3c08390. [PMID: 38417149]
  • Seung-Hyeon Lee, Jiwon Choi, Jae Young Park, Ha-Rim Kim, Myeongkuk Shim, Kyunghyun Im, Hyeonjeong Choe, Jae-Chul Choi, Young-Chul Park, Tae-Gyu Lim, Hyangyim Seo, Hansu Jang, Boung-Jun Oh, Seon-Young Kim, Mi Hee Park. Anti-Obesity Effect and Signaling Mechanism of Potassium Poly-γ-Glutamate Produced by Bacillus subtilis Chungkookjang in High-Fat Diet-Induced Obese Mice. Nutrients. 2024 Mar; 16(6):. doi: 10.3390/nu16060809. [PMID: 38542720]
  • Jing Li, Yang Sun, Xinyu Xiong, Minda Wang, Lugen Zuo, Yueyue Wang, Zhijun Geng. [Prunetin inhibits TLR4/MyD88 pathway to attenuate intestinal epithelial inflammatory response and ameliorate mouse Crohn's disease-like colitis]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. 2024 Mar; 40(3):199-206. doi: ". [PMID: 38512029]
  • Xuemei Yang, Xinhui Jiang, Changqing Liu, Chuang Yang, Sheng Yao, Hongmei Qiu, Junxia Yang, Ke Wu, Hong Liao, Qingsong Jiang. Daidzein protects endothelial cells against high glucose-induced injury through the dual-activation of PPARα and PPARγ. General physiology and biophysics. 2024 Mar; 43(2):153-162. doi: 10.4149/gpb_2023041. [PMID: 38477605]
  • Iskandar Azmy Harahap, Maciej Kuligowski, Adam Cieslak, Paweł A Kołodziejski, Joanna Suliburska. Effect of Tempeh and Daidzein on Calcium Status, Calcium Transporters, and Bone Metabolism Biomarkers in Ovariectomized Rats. Nutrients. 2024 Feb; 16(5):. doi: 10.3390/nu16050651. [PMID: 38474779]
  • Ying He, Youde Cai, Dingling Wei, Liping Cao, Qiansong He, Yazhou Zhang. Elucidating the mechanisms of formononetin in modulating atherosclerotic plaque formation in ApoE-/- mice. BMC cardiovascular disorders. 2024 Feb; 24(1):121. doi: 10.1186/s12872-024-03774-6. [PMID: 38388385]
  • Magdalena Wójciak, Piotr Drozdowski, Aleksandra Ziemlewska, Martyna Zagórska-Dziok, Zofia Nizioł-Łukaszewska, Tomasz Kubrak, Ireneusz Sowa. ROS Scavenging Effect of Selected Isoflavones in Provoked Oxidative Stress Conditions in Human Skin Fibroblasts and Keratinocytes. Molecules (Basel, Switzerland). 2024 Feb; 29(5):. doi: 10.3390/molecules29050955. [PMID: 38474467]
  • Zhaoqing Song, Fengyue Zhao, Li Chu, Huan Lin, Yuntao Xiao, Zheng Fang, Xuncheng Wang, Jie Dong, Xiangguang Lyu, Deyue Yu, Bin Liu, Junyi Gai, Dongqing Xu. The GmSTF1/2-GmBBX4 negative feedback loop acts downstream of blue-light photoreceptors to regulate isoflavonoid biosynthesis in soybean. Plant communications. 2024 Feb; 5(2):100730. doi: 10.1016/j.xplc.2023.100730. [PMID: 37817409]
  • Luciana Daniela Lario, Camila Gonzalez, María Rocío Meini, Omar Santiago Pillaca-Pullo, Daniela Zuricaray, Laureano Español, María Mercedes Scandiani, Alicia Luque, Paula Casati, Claudia Patricia Spampinato. Exploring soybean cultivar susceptibility to sudden death syndrome: Insights into isoflavone responses and biocontrol potential. Plant science : an international journal of experimental plant biology. 2024 Feb; 339(?):111951. doi: 10.1016/j.plantsci.2023.111951. [PMID: 38072331]
  • Qiang Ai, Mei Han, Cuijing Liu, Limin Yang. Transcriptome-Wide Identification and Expression Analysis of bHLH Family Genes in Iris domestica under Drought and Cu Stress. International journal of molecular sciences. 2024 Feb; 25(3):. doi: 10.3390/ijms25031773. [PMID: 38339051]
  • Jinyong Huang, Jingjie Zheng, Tuerxunjiang Dadihanc, Yanhua Gao, Yong Zhang, Zhiqiang Li, Xi Wang, Li Yu, Wubulikasimu Mijiti, Zengru Xie, Hairong Ma. Isoflavones isolated from chickpea sprouts alleviate ovariectomy-induced osteoporosis in rats by dual regulation of bone remodeling. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 Feb; 171(?):116214. doi: 10.1016/j.biopha.2024.116214. [PMID: 38290254]
  • Yuexin Shao, Yan Yu, Shilong Pang, Liyan Ge, Huaiping Shi. Soybean Isoflavones Ameliorates Lactation Performance in Postpartum Mice by Alleviating Oxidative Stress and Regulating Gut Microflora. Molecular nutrition & food research. 2024 Feb; 68(4):e2300184. doi: 10.1002/mnfr.202300184. [PMID: 38175853]
  • L I Xi, Lin Xiangquan, Chen Dongdong, Liu Hui. B-cell lymphoma-2 phosphorylation at Ser70 site-related autophagy mediates puerarin-inhibited the apoptosis of MC3T3-E1 cells during osteoblastogenesis. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 2024 Feb; 44(1):27-34. doi: 10.19852/j.cnki.jtcm.20231024.002. [PMID: 38213236]
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