Exact Mass: 260.0545528
Exact Mass Matches: 260.0545528
Found 500 metabolites which its exact mass value is equals to given mass value 260.0545528,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Khellin
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents > D011564 - Furocoumarins D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents Khellin is a furochromone that can be isolated from Ammi visnuga L.. Khellin is an EGFR inhibitor with an IC50 of 0.15 μM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects[1][2]. Khellin is a furochromone that can be isolated from Ammi visnuga L.. Khellin is an EGFR inhibitor with an IC50 of 0.15 μM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects[1][2].
Glucose 6-phosphate
Glucose 6 phosphate (alpha-D-glucose 6 phosphate or G6P) is the alpha-anomer of glucose-6-phosphate. There are two anomers of glucose 6 phosphate, the alpha anomer and the beta anomer. Glucose 6 phosphate is an ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed). Glucose-6-phosphate is a phosphorylated glucose molecule on carbon 6. When glucose enters a cell, it is immediately phosphorylated to G6P. This is catalyzed with hexokinase enzymes, thus consuming one ATP. A major reason for immediate phosphorylation of the glucose is so that it cannot diffuse out of the cell. The phosphorylation adds a charged group so the G6P cannot easily cross cell membranes. G6P can travel down two metabolic pathways, glycolysis and the pentose phosphate pathway. In addition to the metabolic pathways, G6P can also be stored as glycogen in the liver if blood glucose levels are high. If the body needs energy or carbon skeletons for syntheses, G6P can be isomerized to Fructose-6-phosphate and then phosphorylated to Fructose-1,6-bisphosphate. Note, the molecule now has 2 phosphoryl groups attached. The addition of the 2nd phosphoryl group is an irreversible step, so once this happens G6P will enter glycolysis and be turned into pyruvate (ATP production occurs). If blood glucose levels are high, the body needs a way to store the excess glucose. After being converted to G6P, phosphoglucose mutase (isomerase) can turn the molecule into glucose-1-phosphate. Glucose-1-phosphate can then be combined with uridine triphosphate (UTP) to form UDP-glucose. This reaction is driven by the hydrolysis of pyrophosphate that is released in the reaction. Now, the activated UDP-glucose can add to a growing glycogen molecule with the help of glycogen synthase. This is a very efficient storage mechanism for glucose since it costs the body only 1 ATP to store the 1 glucose molecule and virtually no energy to remove it from storage. It is important to note that glucose-6-phosphate is an allosteric activator of glycogen synthase, which makes sense because when the level of glucose is high the body should store the excess glucose as glycogen. On the other hand, glycogen synthase is inhibited when it is phosphorylated by protein kinase a during times of high stress or low blood glucose levels. -- Wikipedia [HMDB] Glucose 6-phosphate (G6P, sometimes called the Robison ester) is a glucose sugar phosphorylated at the hydroxy group on carbon 6. Glucose 6-phosphate (G6P) has two anomers: the alpha anomer and the beta anomer. Glucose 6-phosphate is an ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose 6-phosphate (Stedman, 26th ed). When glucose enters a cell, it is immediately phosphorylated to G6P. This is catalyzed with hexokinase enzymes, thus consuming one ATP. A major reason for immediate phosphorylation of the glucose is so that it cannot diffuse out of the cell. The phosphorylation adds a charged group so the G6P cannot easily cross cell membranes. G6P can travel down two metabolic pathways: glycolysis and the pentose phosphate pathway. In addition to the metabolic pathways, G6P can also be stored as glycogen in the liver if blood glucose levels are high. If the body needs energy or carbon skeletons for syntheses, G6P can be isomerized to fructose 6-phosphate and then phosphorylated to fructose 1,6-bisphosphate. Note, the molecule now has 2 phosphoryl groups attached. The addition of the 2nd phosphoryl group is an irreversible step, so once this happens G6P will enter glycolysis and be turned into pyruvate (ATP production occurs). If blood glucose levels are high, the body needs a way to store the excess glucose. After being converted to G6P, phosphoglucose mutase (an isomerase) can turn the molecule into glucose 1-phosphate. Glucose 1-phosphate can then be combined with uridine triphosphate (UTP) to form UDP-glucose. This reaction is driven by the hydrolysis of pyrophosphate that is released in the reaction. Now, the activated UDP-glucose can add to a growing glycogen molecule with the help of glycogen synthase. This is a very efficient storage mechanism for glucose since it costs the body only 1 ATP to store the 1 glucose molecule and virtually no energy to remove it from storage. It is important to note that glucose 6-phosphate is an allosteric activator of glycogen synthase, which makes sense because when the level of glucose is high the body should store the excess glucose as glycogen. On the other hand, glycogen synthase is inhibited when it is phosphorylated by protein kinase during times of high stress or low blood glucose levels. Acquisition and generation of the data is financially supported in part by CREST/JST. CONFIDENCE standard compound; INTERNAL_ID 237 KEIO_ID G003; [MS2] KO009109 KEIO_ID G003
α-D-Glucose-1-phosphate
Glucose 1-phosphate (also called cori ester) is a glucose molecule with a phosphate group on the 1-carbon. It can exist in either the α- or β-anomeric form. Glucose 1-phosphate belongs to the class of organic compounds known as monosaccharide phosphates. These are monosaccharides comprising a phosphated group linked to the carbohydrate unit. Glucose 1-phosphate is the direct product of the reaction in which glycogen phosphorylase cleaves off a molecule of glucose from a greater glycogen structure. It cannot travel down many metabolic pathways and must be interconverted by the enzyme phosphoglucomutase in order to become glucose 6-phosphate. Free glucose 1-phosphate can also react with UTP to form UDP-glucose. It can then return to the greater glycogen structure via glycogen synthase. *Found widely in both plants and animals. A precursor of starch in plants and of glycogen in animals. [CCD] Acquisition and generation of the data is financially supported in part by CREST/JST. COVID info from COVID-19 Disease Map KEIO_ID G020 Corona-virus KEIO_ID G115 Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
Sorbose 1-phosphate
Sorbose 1-phosphate is formed when extracellular sorbose is taken into the cell. The enzyme responsible for this is PTS-Sor-EIIA [EC:2.7.1.69]. Sorbose 1-phosphate has been found to be a metabolite of Klebsiella and Lactobacillus (PMID: 6361004; PMID: 12177329). Sorbose 1-phosphate is formed when extracellular sorbose is taken into the cell. The enzyme responsible for this is PTS-Sor-EIIA [EC:2.7.1.69]. [HMDB]
β-D-Fructose 6-phosphate
Fructose 6-phosphate (F6P) belongs to the class of organic compounds known as hexose phosphates. These are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups. F6P is a derivative of fructose, which has been phosphorylated at the 6-hydroxy group. Fructose 6-phosphate is a fundamental metabolite and exists in all living species, ranging from bacteria to plants to humans. The great majority of glucose is converted to fructose 6-phosphate as part of the glycolytic metabolic pathway (glycolysis). Specifically, F6P is produce is produced by the isomerisation of glucose 6-phosphate via the enzyme phosphoglucose isomerase. F6P is in turn further phosphorylated to fructose-1,6-bisphosphate by the enzyme phosphofructokinase-1. Glycolysis is the metabolic pathway that converts glucose into pyruvic acid. The free energy released in this process is used to form ATP and reduced nicotinamide adenine dinucleotide (NADH). In addition to its key involvement in glycolysis, fructose 6-phosphate can also be biosynthesized from glucosamine 6-phosphate via the enzyme glucosamine-6-phosphate isomerase 1. In addition, fructose 6-phosphate and L-glutamine can be converted into glucosamine 6-phosphate and L-glutamic acid through the action of the enzyme glutamine--fructose-6-phosphate aminotransferase. An important intermediate in the Carbohydrates pathway. The interconversion of glucose-6-phosphate and fructose-6-phosphate, the second step of the Embden-Meyerhof glycolytic pathway, is catalyzed by the enzyme phosphoglucose isomerase (PGI). In gluconeogenesis, fructose-6-phosphate is the immediate precursor of glucose-6-phosphate (wikipedia) [HMDB] Acquisition and generation of the data is financially supported in part by CREST/JST. KEIO_ID F001
Fructose 1-phosphate
Fructose 1-phosphate, also known as D-fructose-1-p, belongs to the class of organic compounds known as hexose phosphates. These are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups. Metabolism of fructose thus essentially results in intermediates of glycolysis. The final product of glycolysis (pyruvate) may then undergo gluconeogenesis, enter the TCA cycle or be stored as fatty acids. Fructose 1-phosphate exists in all living organisms, ranging from bacteria to humans. Within humans, fructose 1-phosphate participates in a number of enzymatic reactions. In particular, fructose 1-phosphate can be biosynthesized from D-fructose through the action of the enzyme ketohexokinase. In addition, fructose 1-phosphate can be converted into dihydroxyacetone phosphate and glyceraldehyde; which is catalyzed by the enzyme fructose-bisphosphate aldolase a. Because fructokinase has a high Vmax fructose entering cells is quickly phosphorylated to fructose 1-phosphate. In humans, fructose 1-phosphate is involved in fructose intolerance, hereditary. Hypoglycemia results from inhibition of glycogenolysis and gluconeogenesis. It is generated mainly by hepatic fructokinase but is also generated in smaller amounts in the small intestinal mucosa and proximal epithelium of the renal tubule. Aldolase B converts it into glyceraldehyde and dihydroxyacetone phosphate (DHAP). Symptoms of hereditary fructose intolerance are apathy, drowsiness, sweatiness and tremulousness. Fructose 1-phosphate is an intermediate metabolite in the Fructose and mannose metabolism pathway. [HMDB] KEIO_ID F009
Norathyriol
A polyphenol metabolite detected in biological fluids [PhenolExplorer]
myo-Inositol 1-phosphate
myo-Inositol 1-phosphate, also known as I1P or ins(1)p, belongs to the class of organic compounds known as inositol phosphates. Inositol phosphates are compounds containing a phosphate group attached to an inositol (or cyclohexanehexol) moiety. myo-Inositol 1-phosphate is a metabolite of inositol phosphate metabolism and the phosphatidylinositol signalling system. Inositol phosphatases (EC:3.1.3.25) play a crucial role in the phosphatidylinositol signalling pathway. Expression is substantially higher in the subcortical regions of the brain, most prominently in the caudate. The phosphatidylinositol pathway is thought to be modified by lithium, a commonly prescribed medication in treating bipolar disorder (OMIM: 605922). Myo-inositol 1-phosphate is a metabolite of the Inositol phosphate metabolism and the Phosphatidylinositol signaling system. Inositol phosphatases [EC:3.1.3.25] play a crucial role in the phosphatidylinositol signaling pathway; in brain, the expression is substantially higher in the subcortical regions, most prominently in the caudate. The phosphatidylinositol pathway is thought to be modified by lithium, a commonly prescribed medication in treating bipolar disorder. (OMIM 605922) [HMDB]
Beta-D-Fructose 2-phosphate
beta-D-Fructose 2-phosphate is involved in the fructose eand mannose system. beta-D-Fructose 2-phosphate is produced from beta-D-Fructose 2,6-bisphosphate by the enzyme fructose-2,6-bisphosphate 6-phosphatase [EC 3.1.3.54]. [HMDB] beta-D-Fructose 2-phosphate is involved in the fructose eand mannose system. beta-D-Fructose 2-phosphate is produced from beta-D-Fructose 2,6-bisphosphate by the enzyme fructose-2,6-bisphosphate 6-phosphatase [EC 3.1.3.54].
Suprofen
Suprofen is only found in individuals that have used or taken this drug. It is an ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. [PubChem]Suprofen binds to the cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) isoenzymes, preventing the synthesis of prostaglandins and reducing the inflammatory response. Cyclooxygenase catalyses the formation of prostaglandins and thromboxane from arachidonic acid (itself derived from the cellular phospholipid bilayer by phospholipase A2). Prostaglandins act (among other things) as messenger molecules in the process of inflammation. The overall result is a reduction in pain and inflammation in the eyes and the prevention of pupil constriction during surgery. Normally trauma to the anterior segment of the eye (especially the iris) increases endogenous prostaglandin synthesis which leads to constriction of the iris sphincter. M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AE - Propionic acid derivatives D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D004791 - Enzyme Inhibitors
Norswertianin
Norswertianin is a member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 2, 6 and 8. It has a role as a plant metabolite. It is a member of xanthones and a polyphenol. Norswertianin is a natural product found in Swertia japonica, Swertia ciliata, and other organisms with data available. A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 2, 6 and 8.
Galactose 1-phosphate
Galactose 1-phosphate, also known as D-Galactose-1-phosphate or alpha-D-gal-1-P, belongs to the class of organic compounds known as monosaccharide phosphates. These are monosaccharides comprising a phosphate group linked to the carbohydrate unit. Galactose-1-phosphate is an intermediate in the interconversion of glucose and uridine diphosphate galactose. Galactose 1-phosphate exists in all living species, ranging from bacteria to plants to humans. Within humans, galactose 1-phosphate participates in a number of enzymatic reactions. In particular, uridine diphosphate glucose and galactose 1-phosphate can be biosynthesized from uridine diphosphategalactose and glucose 1-phosphate; which is mediated by the enzyme galactose-1-phosphate uridylyltransferase (GALT). In addition, galactose 1-phosphate can be biosynthesized from D-galactose through the action of the enzyme galactokinase. The improper metabolism of galactose-1-phosphate is a characteristic of a condition known as galactosemia (PMID: 7671964). Type I galactosemia is a genetic disorder that is caused by the impairment of galactose-1-phosphate uridylyltransferase (EC 2.7.7.12). Evidence suggests that misfolding of the galactose 1-phosphate uridylyltransferase enzyme is the underlying cause of type I galactosemia (PMID: 23583749). Outside of the human body, galactose 1-phosphate has been detected, but not quantified in, several different foods, such as gooseberries, anises, turmerics, caraway, and cumins. COVID info from COVID-19 Disease Map Occurs in liver, milk, and yeasts Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Acquisition and generation of the data is financially supported in part by CREST/JST.
Mannose 6-phosphate
Mannose 6-phosphate, also known as alpha-D-mannose-6-p or man-6-p, belongs to the class of organic compounds known as hexose phosphates. These are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups. Mannose 6-phosphate exists in all eukaryotes, ranging from yeast to humans. Within humans, mannose 6-phosphate participates in a number of enzymatic reactions. In particular, mannose 6-phosphate can be converted into fructose 6-phosphate through its interaction with the enzyme mannose-6-phosphate isomerase. In addition, mannose 6-phosphate can be biosynthesized from D-mannose through the action of the enzyme hexokinase-1. Mannose 6-phosphate is a potent competitive inhibitor of pinocytosis of human platelet beta-glucuronidase and it is a necessary component of the recognition marker on the enzyme for pinocytosis by human fibroblasts as well (PMID 908752). In humans, mannose 6-phosphate is involved in fructose intolerance, hereditary. Mannose-6-phosphate is a potent competitive inhibitor of pinocytosis of human platelet beta-glucuronidase and it is a necessary component of the recognition marker on the enzyme for pinocytosis by human fibroblasts as well (PMID 908752). [HMDB] Acquisition and generation of the data is financially supported in part by CREST/JST. KEIO_ID M008
D-myo-Inositol 4-phosphate
D-myo-Inositol 4-phosphate, also known as inositol 4-phosphoric acid, belongs to the class of organic compounds known as inositol phosphates. Inositol phosphates are compounds containing a phosphate group attached to an inositol (or cyclohexanehexol) moiety. D-myo-Inositol 4-phosphate is an extremely weak basic (essentially neutral) compound (based on its pKa). Within humans, D-myo-inositol 4-phosphate participates in a number of enzymatic reactions. In particular, D-myo-inositol 4-phosphate can be biosynthesized from D-myo-inositol 1,4-bisphosphate through its interaction with the enzyme inositol polyphosphate 1-phosphatase. In addition, D-myo-inositol 4-phosphate can be converted into myo-inositol through its interaction with the enzyme inositol monophosphatase 1. D-Myo-inositol 4-phosphate is a substrate for Inositol monophosphatase, Inositol polyphosphate 1-phosphatase and Inositol monophosphatase 2. [HMDB]
beta-D-Glucose 6-phosphate
beta-D-Glucose 6 phosphate (b-G6P) is the beta-anomer of glucose-6-phosphate. There are two anomers of glucose 6 phosphate: the alpha anomer and the beta anomer. Specifically, beta-D-Glucose 6-phosphate is glucose sugar phosphorylated on carbon 6. It is a very common metabolite in cells as the vast majority of glucose entering a cell will become phosphorylated in this way. The primary reason for the immediate phosphorylation of glucose is to prevent diffusion out of the cell. The phosphorylation adds a charged phosphate group so the glucose 6-phosphate cannot easily cross the cell membrane. b-G6P is involved in glycolysis, gluconeogenesis, pentose phosphate, and glycogen and sucrose metabolic pathways. beta-D-Glucose 6 phosphate can be generated through beta-D-fructose phosphate or alpha-D-glucose 6 phosphate (via glucose-6-phosphate isomerase) or beta-D glucose (via hexokinase). It can then be sent off to the pentose phosphate pathway which generates the useful cofactor NADPH as well as ribulose 5-phosphate, a carbon source for the synthesis of other molecules. Alternately, if the cell needs energy or carbon skeletons for synthesis then glucose 6-phosphate is targeted for glycolysis. A third route is to have glucose 6 phosphate stored or converted into glycogen, especially if blood glucose levels are high. Beta-d-glucose 6-phosphate, also known as B-D-glucose 6-(dihydrogen phosphoric acid) or 6-O-phosphono-beta-D-glucopyranose, is a member of the class of compounds known as hexose phosphates. Hexose phosphates are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups. Beta-d-glucose 6-phosphate is soluble (in water) and a moderately acidic compound (based on its pKa). Beta-d-glucose 6-phosphate can be found in a number of food items such as sapodilla, hickory nut, atlantic herring, and swede, which makes beta-d-glucose 6-phosphate a potential biomarker for the consumption of these food products. Beta-d-glucose 6-phosphate exists in all living species, ranging from bacteria to humans. In humans, beta-d-glucose 6-phosphate is involved in several metabolic pathways, some of which include glycolysis, glycogenosis, type IC, glycogenosis, type IB, and trehalose degradation. Beta-d-glucose 6-phosphate is also involved in several metabolic disorders, some of which include glucose-6-phosphate dehydrogenase deficiency, warburg effect, fanconi-bickel syndrome, and transaldolase deficiency.
Beta-D-Fructose 6-phosphate
Beta-D-Fructose 6 phosphate (b-F6P) is the beta-anomer of fructose-6-phosphate. There are two anomers of fructose 6 phosphate, the alpha anomer and the beta anomer. Specifically, beta-D-fructose 6-phosphate is fructose sugar phosphorylated on carbon 6. Beta-D-Fructose 6-phosphate is a substrate for Fructose-1,6-bisphosphatase, Pyruvate kinase (isozymes R/L), Hexokinase (type I), Fructose-bisphosphate aldolase A, L-lactate dehydrogenase B chain, Glyceraldehyde-3-phosphate dehydrogenase (liver) and Transaldolase. [HMDB] Beta-D-Fructose 6 phosphate (b-F6P) is the beta-anomer of fructose-6-phosphate. There are two anomers of fructose 6 phosphate, the alpha anomer and the beta anomer. Specifically, beta-D-fructose 6-phosphate is fructose sugar phosphorylated on carbon 6. Beta-D-Fructose 6-phosphate is a substrate for Fructose-1,6-bisphosphatase, Pyruvate kinase (isozymes R/L), Hexokinase (type I), Fructose-bisphosphate aldolase A, L-lactate dehydrogenase B chain, Glyceraldehyde-3-phosphate dehydrogenase (liver) and Transaldolase.
D-Mannose 1-phosphate
D-Mannose 1-phosphate (CAS: 27251-84-9) is a normal metabolite intermediate in fructose and mannose metabolism. It is a substrate of phosphomannomutase 1 (PMM, EC 5.4.2.8), an enzyme necessary for the synthesis of GDP-mannose (a substrate for dolichol-linked oligosaccharide synthesis). PMM converts mannose 6-phosphate into mannose-1-phosphate. A deficiency of phosphomannomutase in carbohydrate-deficient glycoprotein syndrome (CDGS) type I is associated with a decreased synthesis of mannose 1-phosphate. CDGS is a group of autosomal recessively transmitted disorders in which abnormally glycosylated proteins are formed (PMID: 9451026, 8549746, 12729595). α-d-mannose 1-phosphate is a member of the class of compounds known as monosaccharide phosphates. Monosaccharide phosphates are monosaccharides comprising a phosphated group linked to the carbohydrate unit. α-d-mannose 1-phosphate is soluble (in water) and a moderately acidic compound (based on its pKa). α-d-mannose 1-phosphate can be found in a number of food items such as lettuce, beech nut, red beetroot, and japanese pumpkin, which makes α-d-mannose 1-phosphate a potential biomarker for the consumption of these food products. Acquisition and generation of the data is financially supported in part by CREST/JST. KEIO_ID M080
D-myo-Inositol 3-phosphate
D-myo-Inositol 3-phosphate, also known as inositol 3-phosphoric acid, belongs to the class of organic compounds known as inositol phosphates. Inositol phosphates are compounds containing a phosphate group attached to an inositol (or cyclohexanehexol) moiety. D-myo-Inositol 3-phosphate is an extremely weak basic (essentially neutral) compound (based on its pKa). D-myo-Inositol 3-phosphate is involved in the inositol phosphate metabolism and the phosphatidylinositol signalling systems. D-myo-Inositol 3-phosphate is created from D-myo-inositol 3,4-bisphosphate by inositol polyphosphate-4-phosphatase (EC 3.1.3.66) and is converted into myo-inositol by myo-inositol-1(or 4)-monophosphatase (EC 3.1.3.25). Myo-inositol 1-phosphate is a metabolite of the Inositol phosphate metabolism and the Phosphatidylinositol signaling system. Inositol phosphatases [EC:3.1.3.25] play a crucial role in the phosphatidylinositol signaling pathway; in brain, the expression is substantially higher in the subcortical regions, most prominently in the caudate. The phosphatidylinositol pathway is thought to be modified by lithium, a commonly prescribed medication in treating bipolar disorder. (OMIM 605922) [HMDB]
D-Tagatose 6-phosphate
D-Tagatose 6-phosphate is an intermediate in galactose metabolism. [HMDB] D-Tagatose 6-phosphate is an intermediate in galactose metabolism.
[(2R,3R,4S,5S)-3,4,5,6-Tetrahydroxyoxan-2-yl]methyl dihydrogen phosphate
Tiazofurin
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C272 - Antimetabolite C471 - Enzyme Inhibitor > C2087 - Inosine Monophosphate Dehydrogenase Inhibitor L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents D009676 - Noxae > D000963 - Antimetabolites D000970 - Antineoplastic Agents
alpha-D-Glucose 6-phosphate
A D-glucopyranose 6-phosphate where alpha-D-glucose is the sugar component. [Spectral] alpha-D-Glucose 6-phosphate (exact mass = 260.02972) and L-Isoleucine (exact mass = 131.09463) and 3-Sulfino-L-alanine (exact mass = 153.00958) were not completely separated on HPLC under the present analytical conditions as described in AC$XXX. Additionally some of the peaks in this data contains dimers and other unidentified ions. [Spectral] alpha-D-Glucose 6-phosphate (exact mass = 260.02972) and 3-Sulfino-L-alanine (exact mass = 153.00958) were not completely separated on HPLC under the present analytical conditions as described in AC$XXX. Additionally some of the peaks in this data contains dimers and other unidentified ions.
Galactose 1-phosphate
A D-galactopyranose 1-phosphate having alpha-configuration at the anomeric centre. COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS α-d-galactose 1-phosphate, also known as alpha-D-galactopyranosyl phosphate or A-D-galactopyranose 1-phosphoric acid, is a member of the class of compounds known as monosaccharide phosphates. Monosaccharide phosphates are monosaccharides comprising a phosphated group linked to the carbohydrate unit. α-d-galactose 1-phosphate is soluble (in water) and a moderately acidic compound (based on its pKa). α-d-galactose 1-phosphate can be found in a number of food items such as kai-lan, cinnamon, macadamia nut (m. tetraphylla), and durian, which makes α-d-galactose 1-phosphate a potential biomarker for the consumption of these food products. α-d-galactose 1-phosphate can be found primarily in blood, as well as in human erythrocyte and red blood cell tissues. α-d-galactose 1-phosphate exists in all living species, ranging from bacteria to humans. In humans, α-d-galactose 1-phosphate is involved in few metabolic pathways, which include galactose metabolism, lactose synthesis, and nucleotide sugars metabolism. α-d-galactose 1-phosphate is also involved in several metabolic disorders, some of which include GLUT-1 deficiency syndrome, congenital disorder of glycosylation cdg-iid, galactosemia III, and galactosemia.
[(2R,3S,4R)-3,4,5-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]methyl dihydrogen phosphate
L-tagatofuranose 6-phosphate
The furanose form of L-tagatose 6-phosphate.
L-Galactose 1-phosphate
A galactose phosphate compound with undefined anomeric stereochemistry having L-configuration and the phosphate group at the 1-position. A L-galactose 1-phosphate compound having beta-configuration about the anomeric centre.
Khellin
Khellin is a furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator. It has a role as a vasodilator agent, a bronchodilator agent, an anti-asthmatic agent and a cardiovascular drug. It is an organic heterotricyclic compound, an oxacycle and a furanochromone. It is functionally related to a 5H-furo[3,2-g]chromen-5-one. Khellin is a natural product found in Ammi visnaga, Annona muricata, and other organisms with data available. A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024) See also: Visnaga daucoides fruit (part of). D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents > D011564 - Furocoumarins D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents Khellin is a furochromone that can be isolated from Ammi visnuga L.. Khellin is an EGFR inhibitor with an IC50 of 0.15 μM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects[1][2]. Khellin is a furochromone that can be isolated from Ammi visnuga L.. Khellin is an EGFR inhibitor with an IC50 of 0.15 μM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects[1][2].
Tiaprofenic acid
Tiaprofenic acid is only found in individuals that have used or taken this drug. It is a non-steroidal anti-inflammatory drug of the arylpropionic acid (profen) class, used to treat pain, especially arthritic pain.Tiaprofenic acid belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the production of a chemical (prostaglandin) which the body produces in response to injury or certain diseases. This prostaglandin would otherwise go on to cause swelling, pain and inflammation. M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AE - Propionic acid derivatives C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents
D-Tagatose 1-phosphate
D-tagatose is a stereoisomer of D-fructose, which is phosphorylated to D-tagatose-1-phosphate by fructokinase in the liver. Slow degradation rate of D-tagatose-1-phosphate, cause accumulation, and ingested D-tagatose may therefore cause a longer lasting reduction in inorganic phosphate (Pi) and adenosine triphosphate (ATP) levels in the liver compared with D-fructose. It is also seen in patients with hereditary fructose intolerance, this may increase purine nucleotide degradation and thereby increase uric acid production. (PMID: 11079825) [HMDB] D-tagatose is a stereoisomer of D-fructose, which is phosphorylated to D-tagatose-1-phosphate by fructokinase in the liver. Slow degradation rate of D-tagatose-1-phosphate, cause accumulation, and ingested D-tagatose may therefore cause a longer lasting reduction in inorganic phosphate (Pi) and adenosine triphosphate (ATP) levels in the liver compared with D-fructose. It is also seen in patients with hereditary fructose intolerance, this may increase purine nucleotide degradation and thereby increase uric acid production. (PMID: 11079825).
5-[2-(3,5-Dihydroxyphenyl)ethenyl]benzene-1,2,3-triol
2-Methoxystypandrone
2-Methoxystypandrone is found in green vegetables. 2-Methoxystypandrone is isolated from roots of Polygonum cuspidatum (Japanese knotweed). Isolated from roots of Polygonum cuspidatum (Japanese knotweed). 2-Methoxystypandrone is found in green vegetables.
Orientalone
Orientalone is found in fruits. Orientalone is a constituent of Prunus cerasoides (wild Himalayan cherry). Constituent of Prunus cerasoides (wild Himalayan cherry). Orientalone is found in fruits.
Pratenol A
Pratenol A is found in herbs and spices. Pratenol A is a constituent of Trifolium pratense (red clover). Constituent of Trifolium pratense (red clover). Pratenol A is found in tea and herbs and spices.
5-[2-(3,4-Dihydroxyphenyl)ethenyl]benzene-1,2,3-triol
Dolichyl phosphate D-mannose
Dolichyl phosphate D-mannose (DPM) is an intermediate in the biosynthesis of N-glycans. It is a substrate for dolichol-phosphate mannosyltransferase (PMID: 10835346). Dolichol-phosphate mannosyltransferase is a heterotrimeric protein embedded in the endoplasmic reticulum membrane. The first subunit of the heterotrimer appears to be the actual catalyst, and the other two subunits appear to stabilize it. More specifically, dolichol-phosphate-mannose is the donor of mannose groups in the synthesis of the dolichol pyrophosphate-linked precursor oligosaccharide in asparagine-linked glycosylation, in the synthesis of glycosyl phosphatidylinositol (GPI) anchor precursors, in protein O-mannosylation and in protein C-mannosylation. Its synthesis proceeds in two steps. First, cytosolic GDP-mannose reacts with dolichol phosphate exposed on the cytosolic face of the endoplasmic reticulum membrane to form DPM with its mannose moiety oriented toward the cytosol. The DPM molecule then flips in the endoplasmic reticulum membrane, so that its mannose moiety is in the endoplasmic reticulum lumen, accessible to the enzymes that catalyze its transfer to growing glycolipids and glycoproteins. (PMID: 11102867). Dolichyl phosphate D-mannose is also a substrate for protein O-mannosyl-transferase 2 and protein O-mannosyl-transferase 1. [HMDB] Dolichyl phosphate D-mannose (DPM) is an intermediate in the biosynthesis of N-glycans. It is a substrate for dolichol-phosphate mannosyltransferase (PMID: 10835346). Dolichol-phosphate mannosyltransferase is a heterotrimeric protein embedded in the endoplasmic reticulum membrane. The first subunit of the heterotrimer appears to be the actual catalyst, and the other two subunits appear to stabilize it. More specifically, dolichol-phosphate-mannose is the donor of mannose groups in the synthesis of the dolichol pyrophosphate-linked precursor oligosaccharide in asparagine-linked glycosylation, in the synthesis of glycosyl phosphatidylinositol (GPI) anchor precursors, in protein O-mannosylation and in protein C-mannosylation. Its synthesis proceeds in two steps. First, cytosolic GDP-mannose reacts with dolichol phosphate exposed on the cytosolic face of the endoplasmic reticulum membrane to form DPM with its mannose moiety oriented toward the cytosol. The DPM molecule then flips in the endoplasmic reticulum membrane, so that its mannose moiety is in the endoplasmic reticulum lumen, accessible to the enzymes that catalyze its transfer to growing glycolipids and glycoproteins. (PMID: 11102867). Dolichyl phosphate D-mannose is also a substrate for protein O-mannosyl-transferase 2 and protein O-mannosyl-transferase 1.
myo-Inositol 6-phosphate
myo-Inositol 6-phosphate, also known as I6P or Ins(6)P, belongs to the class of organic compounds known as inositol phosphates. Inositol phosphates are compounds containing a phosphate group attached to an inositol (or cyclohexanehexol) moiety. Inositol phosphate is an intermediate step in the metabolism of glucose-6-phosphate into myo-inositol. myo-Inositol is synthesized from glucose-6-phosphate (G-6-P) in two steps. First, G-6-P is isomerized by INYNA1 into myo-inositol 1-phosphate, which is then dephosphorylated by IMPA1 to give myo-inositol. An intermediate step in the metabolism of glucose-6-phosphate to myo-inositol. myo-Inositol is synthesized from glucose-6-phosphate (G-6-P) in two steps. First, G-6-P is isomerised by INYNA1 to myo-inositol 1-phosphate, which is then dephosphorylated by IMPA1 to give myo-inositol [HMDB]
Urolithin D
Urolithin D is a biomarker of nut consumption in urine. Urolithin D is competitive and reversible antagonist of EphA receptors. Urolithin D exhibits intra-classes selectivity[1].
D-fructose 1-phosphate
D-fructose 1-phosphate, also known as 1-O-phosphono-D-fructose or fructose-1-phosphate, barium salt, (D)-isomer, is a member of the class of compounds known as monosaccharide phosphates. Monosaccharide phosphates are monosaccharides comprising a phosphated group linked to the carbohydrate unit. D-fructose 1-phosphate is soluble (in water) and a moderately acidic compound (based on its pKa). D-fructose 1-phosphate can be found in a number of food items such as rye, ucuhuba, sugar apple, and spelt, which makes D-fructose 1-phosphate a potential biomarker for the consumption of these food products. D-fructose 1-phosphate exists in all eukaryotes, ranging from yeast to humans. This compound belongs to the family of Monosaccharide Phosphates. These are monosaccharides comprising a phosphated group linked tot he carbohydrate unit.
(2,3,4,5,6-Pentahydroxycyclohexyl) dihydrogen phosphate
(2R,3R,4S,5R)-2,3,4,5-Tetrahydroxy-6-oxohexyl dihydrogen phosphate
3-Thiacytidine
4-Thiouridine
Dezinamide
C11H11F3N2O2 (260.07725819999996)
C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent
Pyrano(2,3-c)pyrazol-6(2H)-one, 3,4-dimethyl-2-(2-thienylmethyl)-
Motapizone
C471 - Enzyme Inhibitor > C744 - Phosphodiesterase Inhibitor
N-Hydroxysuccinimidyl-4-azidobenzoate
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D003432 - Cross-Linking Reagents D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D000345 - Affinity Labels
Fructose-6-Phosphate (closed form)
2-Amino-9-(4-amino-2-oxopyrimidin-1-yl)-1H-purin-6-one
Kitagine
Constituent of Canavalia ensiformis (jack bean) seeds. Kitagine is found in pulses.
D-mannose 6-phosphate
D-mannose 6-phosphate, also known as mannose-6-phosphate disodium salt, is a member of the class of compounds known as hexose phosphates. Hexose phosphates are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups. D-mannose 6-phosphate is soluble (in water) and a moderately acidic compound (based on its pKa). D-mannose 6-phosphate can be found in a number of food items such as bog bilberry, wild celery, common pea, and breadnut tree seed, which makes D-mannose 6-phosphate a potential biomarker for the consumption of these food products. D-mannose 6-phosphate may be a unique S.cerevisiae (yeast) metabolite. The M6P-tagged lysosomal enzymes are shipped to the late endosomes via vesicular transport. Enzyme replacement therapy (ERT) for several lysosomal storage diseases relies on this pathway to efficiently direct synthetic enzymes to the lysosome where each can metabolize its particular substrate. The pH in the late endosome can reach 6.0, which causes dissociation of M6P from its receptor. Upon release, the enzymes are ferried to their final destination in the lysosomes. The MPRs are packed into vesicles that bud off the late endosome and return to the "trans"-Golgi network. In this way, the MPRs can be recycled . D-mannose 6-phosphate, also known as mannose-6-phosphate disodium salt, is a member of the class of compounds known as hexose phosphates. Hexose phosphates are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups. D-mannose 6-phosphate is soluble (in water) and a moderately acidic compound (based on its pKa). D-mannose 6-phosphate can be found in a number of food items such as bog bilberry, wild celery, common pea, and breadnut tree seed, which makes D-mannose 6-phosphate a potential biomarker for the consumption of these food products. D-mannose 6-phosphate may be a unique S.cerevisiae (yeast) metabolite. The M6P-tagged lysosomal enzymes are shipped to the late endosomes via vesicular transport. Enzyme replacement therapy (ERT) for several lysosomal storage diseases relies on this pathway to efficiently direct synthetic enzymes to the lysosome where each can metabolize its particular substrate. The pH in the late endosome can reach 6.0, which causes dissociation of M6P from its receptor. Upon release, the enzymes are ferried to their final destination in the lysosomes. The MPRs are packed into vesicles that bud off the late endosome and return to the "trans"-Golgi network. In this way, the MPRs can be recycled.
Bellidin
Bellidin is a member of the class of xanthones that is xanthone which is substituted by hydroxy groups at positions 1, 3, 5, and 8. A natural product found particularly in Iris nigricans and Gentiana campestris. It has a role as a metabolite, an EC 3.1.1.7 (acetylcholinesterase) inhibitor, a mutagen, an antioxidant and a radical scavenger. It is a member of xanthones and a tetrol. It is functionally related to a xanthone. 1,3,5,8-Tetrahydroxyxanthone is a natural product found in Gentiana orbicularis, Swertia teres, and other organisms with data available. A member of the class of xanthones that is xanthone which is substituted by hydroxy groups at positions 1, 3, 5, and 8. A natural product found particularly in Iris nigricans and Gentiana campestris.
Glucose 1-phosphate
COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one
D-fructofuranose 6-phosphate
The five-membered ring form of D-fructose 6-phosphate.
(+-)(?)-13-Acetoxy-12-chlor-trideca-2t,10t-dien-4,6,8-triin|(+-)-13-Acetoxy-12-chlor-trideca-2t,10t-dien-4,6,8-triin|(+-)-13-acetoxy-12-chloro-trideca-2t,10t-diene-4,6,8-triyne|(-)-13-Acetoxy-12-chlor-trideca-2t,10t-dien-4,6,8-triin|(-)-13-acetoxy-12-chloro-trideca-2t,10t-diene-4,6,8-triyne|1-acetoxy-2-chloro-trideca-3E,11E-diene-5,7,9-triyne|trans,trans-1-Acetoxy-2-chlor-tridecadien-(3,11)-triin-(5,7,9)
7-acetyl-2-hydroxy-8-methoxy-6-methyl-1 ,4-naphthoquinone
9-Hydroxyeriobofuran
9-Hydroxyeriobofuran is a natural product found in Pyracantha coccinea and Berberis koreana with data available.
1-(4-Hydroxyphenyl)-2-hydroxy-2-(3,5-dihydroxyphenyl)ethanone
3,4-dihydroxy-5-methoxy-3-methylnaphtho[2,3-c]furan-1(3H)-one|eleucanarol
4,8-Dihydroxy-2,7-dimethoxy-6-methylnaphthalene-1-carboxylic acid 1,8-lactone
1-(2,3,5-trihydroxyphenyl)-2-(4-hydroxyphenyl)ethane-1,2-(E)-epoxide|tricuspidatin A
2,9-dihydroxy-7-methoxy-4-methylnaphtho[1,2-b]furan-3(2h)-one
Methanone, (2,5-dihydroxy-4-methoxyphenyl)(2-hydroxyphenyl)-
1,3,6,7-Tetrahydroxyxanthon|2,4,6,7-tetrahydroxyxanthone
6-Hydroxy-5,7-dimethoxynaphtho[2,3-c]furan-1(3H)-one
5,8-dihydroxy-1-hydroxymethylnaphtho[2,3-c]furan-4,9-dione
1-Hydroxy-3,6-bis[2-(methylthio)ethyl]-2(1H)-pyrazinone
5,8-dihydroxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione
Norathyriol
Norathyriol is a member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 6 and 7. Isolated from Garcinia mangostana and Maclura pomifera, it exhibits inhibitory activity against protein kinase C. It has a role as an antineoplastic agent, an EC 2.7.11.13 (protein kinase C) inhibitor and a plant metabolite. It is a member of xanthones and a polyphenol. Norathyriol is a natural product found in Hypericum aucheri, Hypericum elegans, and other organisms with data available. A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 6 and 7. Isolated from Garcinia mangostana and Maclura pomifera, it exhibits inhibitory activity against protein kinase C.
4-Methyl-6-(3,4-dihydroxystyryl)-2-pyrone
1,3,5,6-Tetrahydroxyxantone
1,3,5,6-Tetrahydroxyxanthone is a natural product found in Hypericum scabrum, Hypericum androsaemum, and other organisms with data available.
suprofen
M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AE - Propionic acid derivatives D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D004791 - Enzyme Inhibitors
D-Glucose 6-phosphate
The open-chain form of D-glucose 6-phosphate.
alpha-D-(+)-mannose-1-phosphate sodium salt hydrate
alpha-D-glucose-1-phosphate dipotassium salt dihydate
4,9-dimethoxy-7-methylfuro[3,2-g]chromen-5-one
4-thiouridine
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D000345 - Affinity Labels D009676 - Noxae > D000963 - Antimetabolites 4-Thiouridine is a ribonucleoside analog, it is widely used in RNA analysis and (m)RNA labeling. 4-Thiouridine inhibits rRNA synthesis and causes a nucleolar stress response[1].
tiaprofenic acid
M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AE - Propionic acid derivatives C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents
4,9-dimethoxy-7-methylfuro[3,2-g]chromen-5-one [IIN-based: Match]
4,9-dimethoxy-7-methylfuro[3,2-g]chromen-5-one [IIN-based on: CCMSLIB00000849010]
alpha-D-Glucose 1-phosphate
A D-glucopyranose 1-phosphate in which the anomeric centre has alpha-configuration.
Urolithin D
Urolithin D is competitive and reversible antagonist of EphA receptors. Urolithin D exhibits intra-classes selectivity[1].
N-[2-Nitro-4-(trifluoromethyl)phenyl]pyrrolidine
C11H11F3N2O2 (260.07725819999996)
1-(4-ethoxyphenyl)-4,4,4-trifluorobutane-1,3-dione
ethyl 3-oxo-3-(2,4,5-trifluoro-3-methylphenyl)propanoate
7-METHOXY-4,5-DIHYDRONAPHTHO[1,2-B]THIOPHENE-2-CARBOXYLIC ACID
Uridine, 2-deoxy-5-mercapto-
D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents D000890 - Anti-Infective Agents > D000998 - Antiviral Agents
2-Trifluoromethyl-5,6,7,8-tetrahydro-[1,6]naphthyridine-3-carboxylic acid methyl ester
C11H11F3N2O2 (260.07725819999996)
6-methyl-4-oxo-3-phenylmethoxypyran-2-carboxylic acid
2-Amino-4-(3,4-dimethoxyphenyl)thiophene-3-carbonitrile
1-(2-chloroethyl)-4-prop-2-enylpiperazine,dihydrochloride
C9H19Cl3N2 (260.06137440000003)
1-(2-AMINOETHYL)-2-METHYL-5-NITROIMIDAZOLE DIHYDROCHLORIDE MONOHYDRATE
3-CHLORO-3,5-DIMETHYL-[1,1-BIPHENYL]-4-CARBOXYLIC ACID
2-CHLORO-2,4-DIMETHYL-[1,1-BIPHENYL]-4-CARBOXYLIC ACID
2-METHYL-4-OXO-4-(4-TRIFLUOROMETHYLPHENYL)BUTYRIC ACID
(4-AMINO-1-METHYL-PYRROL-2-YL)-MORPHOLIN-4-YL-METHANONE
(S)-N-(1-hydroxypropan-2-yl)-2-nitrobenzenesulfonamide
(s)-3-amino-4-(4-nitrophenyl)butanoic acid hydrochloride
4-(Trifluoromethyl)benzamidine hydrochloride dihydrate
3-Chloro-6-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]pyridazine
3-(4-METHOXYPHENOXY)-PROPYL METHANESULF&
C11H16O5S (260.07184060000003)
3-oxo-3-(3-trifluoromethylphenyl)propionic acid ethyl ester
1,3-Propanediol,2,2-dimethyl-, 1,3-dimethanesulfonate
2-CHLORO-6-(BETA-D-2-DEOXYRIBOFURANOSYL)-3,5-DIAMINOPYRAZINE
3-oxo-3-(2-trifluoromethylphenyl)propionic acid ethyl ester
2-(5-phenyl-2h-[1,2,4]triazol-3-yl)-ethylamine dihydrochloride
4-Chloro-7-isopropoxy-6-methyl-3-quinolinecarbonitrile
4-CHLORO-1-(4-METHOXYPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDINE
2-(4-FLUOROPHENYL)-6-(TRIFLUOROMETHYL)-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE
4-[4-amino-2-(trifluoromethyl)phenyl]morpholin-3-one
C11H11F3N2O2 (260.07725819999996)
(4-METHYLSULFANYL-PHENYL)-PHOSPHONIC ACID DIETHYL ESTER
1-chloro-8-methoxy-4,5-dimethylpyrido[4,3-b]indole
1-(4-Chloro-benzenesulfonyl)-piperazine
C10H13ClN2O2S (260.03862280000004)
N-(PIPERIDIN-3-YL)-2-(THIOPHEN-3-YL)ACETAMIDE HYDROCHLORIDE
N-(PIPERIDIN-4-YL)-2-(THIOPHEN-3-YL)ACETAMIDE HYDROCHLORIDE
N-(PIPERIDIN-3-YLMETHYL)THIOPHENE-3-CARBOXAMIDE HYDROCHLORIDE
N-(PIPERIDIN-4-YLMETHYL)THIOPHENE-3-CARBOXAMIDE HYDROCHLORIDE
2-CHLORO-5-(PIPERIDINE-1-SULFONYL)-PYRIDINE
C10H13ClN2O2S (260.03862280000004)
3-(4-methylsulfanylphenyl)-1-thiophen-2-ylprop-2-en-1-one
9,10-Dihydro-9-oxa-10-phosphaphenanthrene-10-ethanol 10-oxide
2-beta-Carboxyethylamino-4-aminobenzenesulfonicacid
4-(4-Nitrophenyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
2,2,2-trifluoro-1-(4-methylsulfonylpiperazin-1-yl)ethanone
(6E)-6-[(4-fluorophenyl)methylidene]-7H-[1,3]thiazolo[3,2-a]pyrimidin-5-one
6-[(4-fluorophenyl)methyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one
2-METHYL-4-OXO-4-(3-TRIFLUOROMETHYLPHENYL)BUTYRIC ACID
1-(4-Chlorophenoxy)-3,3-dimethyl-1-chloro-2-butanone
(r)-3-amino-4-(4-nitrophenyl)butanoic acid hydrochloride
1-Ethyl-3-methylimidazolium trifluoromethanesulfonate
(3-Fluorooxetan-3-yl)methyl 4-methylbenzenesulfonate
(3-Methyl-piperazin-1-yl)-(3-methyl-thiophen-2-yl)-methanone hydrochloride
Thiophene-2-carboxylic acid Methyl-piperidin-4-yl-aMide hydrochloride
3-Methyl-thiophene-2-carboxylic acid piperidin-3-ylamide hydrochloride
4-Nitro-D-phenylalanine methyl ester monohydrochloride
5-Methoxy-2-nitro-4-(trifluoroMethyl)phenylacetonitrile
2-Propen-1-one,3-(2-chlorophenyl)-1-(4-fluorophenyl)-
5-(2-Formyl-phenoxymethyl)-furan-2-carboxylic acid methyl ester
5-Hydroxyuridine
5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Perzinfotel
C9H13N2O5P (260.05620580000004)
C26170 - Protective Agent > C1509 - Neuroprotective Agent Perzinfotel (EAA-090) is a potent, selective, and competitive NMDA receptor antagonist with neuroprotective effects. Perzinfotel (EAA-090) shows high affinity (IC50=30 nM) for the glutamate site[1][2].
3,6-Dimethyl-1,4-dioxane-2,5-dione;1,4-dioxane-2,5-dione
D001697 - Biomedical and Dental Materials
1D-myo-inositol 6-phosphate
A myo-inositol monophosphate in which the phosphate group is located at position 6.
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidenepyrimidin-2-one
Pyrano(2,3-c)pyrazol-6(2H)-one, 3,4-dimethyl-2-(2-thienylmethyl)-
6-[(Phenylmethylthio)methyl]imidazo[2,1-b]thiazole
alpha-D-tagatofuranose 6-phosphate
A D-tagatofuranose 6-phosphate with an alpha-configuration at the anomeric position.
D-Mannose 1-phosphate
A mannose phosphate that is D-mannose carrying a phosphate group at position 1.
Dezinamide
C11H11F3N2O2 (260.07725819999996)
C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent
Eskel
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents > D011564 - Furocoumarins D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents Khellin is a furochromone that can be isolated from Ammi visnuga L.. Khellin is an EGFR inhibitor with an IC50 of 0.15 μM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects[1][2]. Khellin is a furochromone that can be isolated from Ammi visnuga L.. Khellin is an EGFR inhibitor with an IC50 of 0.15 μM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects[1][2].
α-D-Glucose 1-phosphate
Alpha-d-glucose-1-phosphate, also known as D-glucose 1-phosphoric acid or alpha-D-glucopyranosyl phosphate, is a member of the class of compounds known as monosaccharide phosphates. Monosaccharide phosphates are monosaccharides comprising a phosphated group linked to the carbohydrate unit. Alpha-d-glucose-1-phosphate is soluble (in water) and a moderately acidic compound (based on its pKa). Alpha-d-glucose-1-phosphate can be found in a number of food items such as guava, purple mangosteen, cocoa bean, and fig, which makes alpha-d-glucose-1-phosphate a potential biomarker for the consumption of these food products. Alpha-d-glucose-1-phosphate exists in E.coli (prokaryote) and yeast (eukaryote).
(2,3,5,6-Tetrahydroxy-4-oxohexyl) dihydrogen phosphate
2-Amino-2-deoxyglucitol 6-phosphate
C6H15NO8P- (260.05352600000003)
[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] dihydrogen phosphate
keto-L-tagatose 6-phosphate
The open chain form of L-tagatose 6-phosphate
2-Amino-2-deoxy-mannitol-6-phosphate
C6H15NO8P- (260.05352600000003)
3-carboxy-9-(methylsulfanyl)-2-oxononanoate
C11H16O5S-2 (260.07184060000003)
2-Hydroxy-6-(2-carboxyphenyl)-6-oxo-2,4-hexadienoate
[(2S,3S,4S)-2,3,4,6-tetrahydroxy-5-oxohexyl] dihydrogen phosphate
[(2S,3S,4S,5S)-2,3,4,5-tetrahydroxy-6-oxohexyl] dihydrogen phosphate
[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] dihydrogen phosphate
[(2S,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methyl dihydrogen phosphate
[(3R,4R,5R)-2,4,5-trihydroxy-3-(hydroxymethyl)oxan-3-yl] dihydrogen phosphate
[(2S,3S,4R,5S)-3,4,5-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]methyl dihydrogen phosphate
[(2R,3S,4S,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] dihydrogen phosphate
[(2S,3S,4R,5S)-2,3,4,5-tetrahydroxyoxan-2-yl]methyl dihydrogen phosphate
[(2S,3S,4S,5S)-2,3,4-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]methyl dihydrogen phosphate
[(2R,3S,4R,5S)-2,3,4,5-tetrahydroxyoxan-2-yl]methyl dihydrogen phosphate
[(2R,3S,4S,5S)-2,3,4-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]methyl dihydrogen phosphate
[(3S,4S,5S)-2,3,4-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]methyl dihydrogen phosphate
[(3S,4R,5S)-2,3,4,5-tetrahydroxyoxan-2-yl]methyl dihydrogen phosphate
3-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-imino-1,3-thiazin-2-one
D-Allose 6-phosphate
An allose phosphate consisting of D-allose having a monophosphate group at the 6-position.
7-Ethyl-8-methylthieno[2,3-b:4,5-b]dipyridine-2,4-diol
5,6-Dihydroxy-2-deoxyuridine
A pyrimidine 2-deoxyribonucleoside having 5,6-dihydroxyuracil as the nucleobase.
2-methyl-N-[(2-thienylcarbonyl)oxy]benzenecarboximidamide
alpha-L-galactose 1-phosphate
A L-galactose 1-phosphate compound having beta-configuration about the anomeric centre.
2-[(2E)-2-(1-thiophen-2-ylethylidene)hydrazinyl]benzoic acid
6-[(Z)-2-hydroxy-3-oxobut-1-enyl]-7-methoxychromen-2-one
6-[(E)-4-hydroxy-3-oxobut-1-enyl]-7-methoxychromen-2-one
[3-(4-Methoxyphenyl)oxiran-2-yl]methyl hydrogen sulate
[(2S,3S,4S,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methyl dihydrogen phosphate
[(3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]methyl dihydrogen phosphate
3,8-Dioxa-4,7-dioxocyclooctane-1,2-dicarboxylic acid dimethyl ester
alpha-D-Glucose-1-phosphate
beta-D-Glucose 6-phosphate
A D-glucopyranose 6-phosphate in which the anomeric centre has beta-configuration.
alpha-D-Mannose 1-phosphate
A D-mannose 1-phosphate with an alpha-configuration at the anomeric position.
D-fructofuranose 1-phosphate
The furanose form of D-fructose 1-phosphate.
D-galactopyranose 6-phosphate
The pyranose form of D-galactose 6-phosphate.
D-Galactopyranose 1-phosphate
A D-galactose phosphate that consists of D-galactopyranose having a single phospho substituent located at the 1-position. It is an intermediate obtained during the the galactose metabolism.
beta-D-mannose 6-phosphate
A D-mannopyranose 6-phosphate with a beta-configuration at the anomeric position.
keto-D-fructose 1-phosphate
The open chain form of D-fructose 1-phosphate.
beta-D-fructofuranose 1-phosphate
A D-fructofuranose 1-phosphate in which the anomeric centre has beta-configuration.
D-mannitol 1-phosphate(2-)
An organophosphate oxoanion arising from deprotonation of the phosphate OH groups of D-mannitol.
D-glucitol 6-phosphate(2-)
Dianion of D-glucitol 1-phosphate arising from deprotonation of the phosphate OH groups; major species at pH 7.3.
beta-D-tagatofuranose 6-phosphate
A D-tagatofuranose 6-phosphate with a beta-configuration at the anomeric position.
6-O-phosphono-beta-D-galactofuranose
A D-galactose 6-phosphate that is beta-D-galactofuranose in which the hydroxy group at position 6 has been converted into the corresponding dihydrogen phosphate derivative.
SUVN-911
SUVN-911 is a potent, selective, brain penetrated and orally bioavailable neuronal nicotinic acetylcholine α4β2 receptor antagonist, with a Ki of 1.5 nM. SUVN-911 has antidepressant activity[1].
(2e)-2-methyl-4-[(2-oxochromen-7-yl)oxy]but-2-enoic acid
(7z)-3,8-dihydroxy-7-(hydroxymethylidene)-6-[(1z)-2-hydroxyprop-1-en-1-yl]naphthalen-1-one
6,10,12-trihydroxy-8-methyl-3-oxatricyclo[7.3.1.0⁵,¹³]trideca-1(13),5,7,9,11-pentaene-2,4-dione
5-[(1e)-2-(3,4-dihydroxyphenyl)ethenyl]benzene-1,2,3-triol
1-[(2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-hydroxypyrimidine-2,4-dione
(2s)-2-(3-hydroxyprop-1-en-2-yl)-2h,3h-[1,4]dioxino[2,3-g]chromen-7-one
(3r)-3,4-dihydroxy-5-methoxy-3-methylnaphtho[2,3-c]furan-1-one
(2e)-4-(7-hydroxy-2-oxochromen-6-yl)-2-methylbut-2-enoic acid
(2s)-2-(3,5-dihydroxyphenyl)-2-hydroxy-1-(4-hydroxyphenyl)ethanone
5-hydroxy-4-(7-hydroxy-2h-chromen-3-yl)-5-methylfuran-2-one
5,8-dihydroxy-1-(hydroxymethyl)naphtho[2,3-c]furan-4,9-dione
5-[(1z)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2,3-triol
7,9,10a-trihydroxy-3-methyl-1h-benzo[g]isochromen-10-one
(2r)-2-hydroxy-3-[(2z)-5-oxofuran-2-ylidene]propyl benzoate
2-methyl-3-(methylsulfanyl)-3h-pyrazino[1,2-a]indole-1,4-dione
1',5'-dihydroxy-4-methyl-1',3'-dihydrospiro[furan-2,2'-naphthalene]-4',5-dione
(1's,2r)-1',5'-dihydroxy-4-methyl-1',3'-dihydrospiro[furan-2,2'-naphthalene]-4',5-dione
4-(7-hydroxy-2-oxochromen-6-yl)-2-methylbut-2-enoic acid
methyl 7-hydroxy-9-oxo-1h,2h,3h-cyclopenta[b]chromene-3-carboxylate
(2s)-2-hydroxy-3-[(2z)-5-oxofuran-2-ylidene]propyl benzoate
1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-hydroxypyrimidine-2,4-dione
6-[(3-hydroxyphenyl)methoxy]-4h,6h-furo[3,2-c]pyran-2-one
(2s,3e,11e)-2-chlorotrideca-3,11-dien-5,7,9-triyn-1-yl acetate
2,4,12-trihydroxy-8-methyl-3-oxatricyclo[7.3.1.0⁵,¹³]trideca-1,4,7,9(13),11-pentaene-6,10-dione
1-[(2r,3s,4r,5s)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylpyrimidin-2-one
8,9-dihydroxy-3-methylpyrano[4,3-c]isochromene-1,6-dione
4-[2-(3-chloro-1h-pyrrol-2-yl)-1,3-oxazol-5-yl]phenol
5,6-dimethoxy-8-oxatricyclo[7.4.0.0²,⁷]trideca-1(9),2(7),3,5,10,12-hexaene-4,11-diol
10-hydroxy-2-(prop-1-en-2-yl)-2h,3h-[1,4]dioxino[2,3-g]chromen-7-one
{4-[(1e)-3-hydroxyprop-1-en-1-yl]-2-methoxyphenyl}oxidanesulfonic acid
(6r)-6-[(3-hydroxyphenyl)methoxy]-4h,6h-furo[3,2-c]pyran-2-one
1-hydroxy-3-(5-oxofuran-2-ylidene)propan-2-yl benzoate
5-[(1e)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2,3-triol
1-[(2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylpyrimidin-2-one
2-hydroxy-3-[(2z)-5-oxofuran-2-ylidene]propyl benzoate
(2e)-3-[(1s,3s,4r)-3-bromo-4-hydroxy-4-methylcyclohexyl]but-2-enal
5-hydroxy-8,8-dimethyl-7h-pyrano[3,2-g]chromene-2,6-dione
2-methyl-4-[(2-oxochromen-7-yl)oxy]but-2-enoic acid
(2r)-2-hydroxy-3-[(2e)-5-oxofuran-2-ylidene]propyl benzoate
6-hydroxy-8-methoxy-3-methyl-2h,3h-cyclopenta[c]isochromene-1,5-dione
2-chlorotrideca-3,11-dien-5,7,9-triyn-1-yl acetate
[4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenyl]oxidanesulfonic acid
(1r)-1-[(1s,4r,5s,8r)-4-hydroxy-1-(sulfanylmethyl)-6,7-dioxabicyclo[3.2.1]oct-2-en-8-yl]ethyl acetate
C11H16O5S (260.07184060000003)
(2s)-10-hydroxy-2-(prop-1-en-2-yl)-2h,3h-[1,4]dioxino[2,3-g]chromen-7-one
2-(3-hydroxyprop-1-en-2-yl)-2h,3h-[1,4]dioxino[2,3-g]chromen-7-one
(1's,2s)-1',5'-dihydroxy-4-methyl-1',3'-dihydrospiro[furan-2,2'-naphthalene]-4',5-dione
(1s,2r,5s,8r)-8-[(1r)-1-hydroxyethyl]-5-(sulfanylmethyl)-6,7-dioxabicyclo[3.2.1]oct-3-en-2-yl acetate
C11H16O5S (260.07184060000003)