Chemical Formula: C14H12O5
Chemical Formula C14H12O5
Found 67 metabolite its formula value is C14H12O5
Khellin
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents > D011564 - Furocoumarins D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents Khellin is a furochromone that can be isolated from Ammi visnuga L.. Khellin is an EGFR inhibitor with an IC50 of 0.15 μM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects[1][2]. Khellin is a furochromone that can be isolated from Ammi visnuga L.. Khellin is an EGFR inhibitor with an IC50 of 0.15 μM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects[1][2].
Khellin
Khellin is a furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator. It has a role as a vasodilator agent, a bronchodilator agent, an anti-asthmatic agent and a cardiovascular drug. It is an organic heterotricyclic compound, an oxacycle and a furanochromone. It is functionally related to a 5H-furo[3,2-g]chromen-5-one. Khellin is a natural product found in Ammi visnaga, Annona muricata, and other organisms with data available. A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024) See also: Visnaga daucoides fruit (part of). D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents > D011564 - Furocoumarins D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents Khellin is a furochromone that can be isolated from Ammi visnuga L.. Khellin is an EGFR inhibitor with an IC50 of 0.15 μM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects[1][2]. Khellin is a furochromone that can be isolated from Ammi visnuga L.. Khellin is an EGFR inhibitor with an IC50 of 0.15 μM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects[1][2].
5-[2-(3,5-Dihydroxyphenyl)ethenyl]benzene-1,2,3-triol
2-Methoxystypandrone
2-Methoxystypandrone is found in green vegetables. 2-Methoxystypandrone is isolated from roots of Polygonum cuspidatum (Japanese knotweed). Isolated from roots of Polygonum cuspidatum (Japanese knotweed). 2-Methoxystypandrone is found in green vegetables.
Orientalone
Orientalone is found in fruits. Orientalone is a constituent of Prunus cerasoides (wild Himalayan cherry). Constituent of Prunus cerasoides (wild Himalayan cherry). Orientalone is found in fruits.
Pratenol A
Pratenol A is found in herbs and spices. Pratenol A is a constituent of Trifolium pratense (red clover). Constituent of Trifolium pratense (red clover). Pratenol A is found in tea and herbs and spices.
5-[2-(3,4-Dihydroxyphenyl)ethenyl]benzene-1,2,3-triol
7-acetyl-2-hydroxy-8-methoxy-6-methyl-1 ,4-naphthoquinone
9-Hydroxyeriobofuran
9-Hydroxyeriobofuran is a natural product found in Pyracantha coccinea and Berberis koreana with data available.
1-(4-Hydroxyphenyl)-2-hydroxy-2-(3,5-dihydroxyphenyl)ethanone
3,4-dihydroxy-5-methoxy-3-methylnaphtho[2,3-c]furan-1(3H)-one|eleucanarol
4,8-Dihydroxy-2,7-dimethoxy-6-methylnaphthalene-1-carboxylic acid 1,8-lactone
1-(2,3,5-trihydroxyphenyl)-2-(4-hydroxyphenyl)ethane-1,2-(E)-epoxide|tricuspidatin A
2,9-dihydroxy-7-methoxy-4-methylnaphtho[1,2-b]furan-3(2h)-one
Methanone, (2,5-dihydroxy-4-methoxyphenyl)(2-hydroxyphenyl)-
6-Hydroxy-5,7-dimethoxynaphtho[2,3-c]furan-1(3H)-one
5,8-dihydroxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione
4-Methyl-6-(3,4-dihydroxystyryl)-2-pyrone
4,9-dimethoxy-7-methylfuro[3,2-g]chromen-5-one
4,9-dimethoxy-7-methylfuro[3,2-g]chromen-5-one [IIN-based: Match]
4,9-dimethoxy-7-methylfuro[3,2-g]chromen-5-one [IIN-based on: CCMSLIB00000849010]
6-methyl-4-oxo-3-phenylmethoxypyran-2-carboxylic acid
5-(2-Formyl-phenoxymethyl)-furan-2-carboxylic acid methyl ester
Eskel
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents > D011564 - Furocoumarins D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents Khellin is a furochromone that can be isolated from Ammi visnuga L.. Khellin is an EGFR inhibitor with an IC50 of 0.15 μM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects[1][2]. Khellin is a furochromone that can be isolated from Ammi visnuga L.. Khellin is an EGFR inhibitor with an IC50 of 0.15 μM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects[1][2].