α-D-Glucose-1-phosphate (BioDeep_00000001754)

 

Secondary id: BioDeep_00000271001, BioDeep_00001868487

natural product human metabolite PANOMIX_OTCML-2023 Endogenous BioNovoGene_Lab2019


代谢物信息卡片


[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] dihydrogen phosphate

化学式: C6H13O9P (260.0297178)
中文名称: D-葡萄糖-1-磷酸, 1-磷酸葡萄糖
谱图信息: 最多检出来源 Homo sapiens(plant) 18.07%

Reviewed

Last reviewed on 2024-09-14.

Cite this Page

α-D-Glucose-1-phosphate. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/α-d-glucose-1-phosphate (retrieved 2024-12-04) (BioDeep RN: BioDeep_00000001754). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C(C1C(C(C(C(O1)OP(=O)(O)O)O)O)O)O
InChI: InChI=1S/C6H13O9P/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13/h2-10H,1H2,(H2,11,12,13)

描述信息

Glucose 1-phosphate (also called cori ester) is a glucose molecule with a phosphate group on the 1-carbon. It can exist in either the α- or β-anomeric form. Glucose 1-phosphate belongs to the class of organic compounds known as monosaccharide phosphates. These are monosaccharides comprising a phosphated group linked to the carbohydrate unit. Glucose 1-phosphate is the direct product of the reaction in which glycogen phosphorylase cleaves off a molecule of glucose from a greater glycogen structure. It cannot travel down many metabolic pathways and must be interconverted by the enzyme phosphoglucomutase in order to become glucose 6-phosphate. Free glucose 1-phosphate can also react with UTP to form UDP-glucose. It can then return to the greater glycogen structure via glycogen synthase.
*Found widely in both plants and animals. A precursor of starch in plants and of glycogen in animals. [CCD]
Acquisition and generation of the data is financially supported in part by CREST/JST.
COVID info from COVID-19 Disease Map
KEIO_ID G020
Corona-virus
KEIO_ID G115
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

54 个代谢物同义名

[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] dihydrogen phosphate; {[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phosphonic acid; {[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phosphonic acid; alpha-D-glucose-1-phosphate dipotassium salt dihydate; alpha-D-Glucopyranosyl phosphoric acid; alpha-delta-Glucopyranosyl phosphate; 1-O-Phosphono-alpha-D-glucopyranose; α-D-Glucopyranosyl phosphoric acid; a-D-Glucopyranosyl phosphoric acid; D-Glucose alpha-1-phosphoric acid; alpha-D-Glucose-1-phosphoric acid; alpha-D-Glucose 1-phosphoric acid; alpha-D-Glucopyranosyl phosphate; D-Glucose 1-dihydrogen phosphate; delta-Glucopyranose 1-phosphate; 1-O-Phosphono-a-D-glucopyranose; 1-O-Phosphono-α-D-glucopyranose; alpha-delta-Glucose 1-phosphate; alpha-delta-Glucose-1-phosphate; α-D-Glucose-1-phosphoric acid; D-Glucose a-1-phosphoric acid; a-D-Glucose-1-phosphoric acid; D-Glucose α-1-phosphoric acid; a-D-Glucose 1-phosphoric acid; α-D-Glucose 1-phosphoric acid; a-D-Glucopyranosyl phosphate; α-D-Glucopyranosyl phosphate; alpha-D-Glucose 1-phosphate; D-Glucose 1-phosphoric acid; D-Glucopyranose 1-phosphate; D-Glucose alpha-1-phosphate; alpha-D-Glucose-1-phosphate; Glucose 1-phosphoric acid; delta-Glucose 1-phosphate; alpha-Glucose-1-phosphate; delta-Glucose-1-phosphate; D-Glucose α-1-phosphate; a-D-Glucose-1-phosphate; α-D-Glucose 1-phosphate; D-Glucose a-1-phosphate; a-D-Glucose 1-phosphate; α-D-Glucose-1-phosphate; Glucose 1-phosphate(2); D-Glucose-1-phosphate; Glucose monophosphate; D-Glucose 1-phosphate; Glucose 1-phosphate; Glucose-1-phosphate; delta-Glucose-1-P; D-Glucose-1-P; Cori ester; Glucose-1P; Glucose 1-phosphate; D-Glucose 1-phosphate



数据库引用编号

44 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(0)

代谢反应

866 个相关的代谢反应过程信息。

Reactome(40)

BioCyc(11)

WikiPathways(10)

Plant Reactome(696)

INOH(6)

PlantCyc(0)

COVID-19 Disease Map(1)

PathBank(102)

PharmGKB(0)

23 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Stephen P Adams, Nima Alaeiilkhchi, Sara Tasnim, James M Wright. Pravastatin for lowering lipids. The Cochrane database of systematic reviews. 2023 09; 9(?):CD013673. doi: 10.1002/14651858.cd013673.pub2. [PMID: 37721222]
  • Caroline Nb Clezar, Carolina Dq Flumignan, Nicolle Cassola, Luis Cu Nakano, Virginia Fm Trevisani, Ronald Lg Flumignan. Pharmacological interventions for asymptomatic carotid stenosis. The Cochrane database of systematic reviews. 2023 Aug; 8(?):CD013573. doi: 10.1002/14651858.cd013573.pub2. [PMID: 37565307]
  • Zi Hao Zhang, Li Chao Yue Sun, Hong Yan Gu, De Chun Jiang, Zhan Miao Yi. Associations between SLCO1B1, APOE and CYP2C9 and lipid-lowering efficacy and pharmacokinetics of fluvastatin: a meta-analysis. Pharmacogenomics. 2023 06; 24(8):475-484. doi: 10.2217/pgs-2023-0004. [PMID: 37318060]
  • Gökçe Ceren Kuşçu, Çevik Gürel, Aylin Buhur, Nefise Ülkü Karabay Yavaşoğlu, Timur Köse, Altuğ Yavaşoğlu, Fatih Oltulu. Fluvastatin alleviates doxorubicin-induced cardiac and renal toxicity in rats via regulation of oxidative stress, inflammation, and apoptosis associated genes expressions. Drug and chemical toxicology. 2023 Mar; 46(2):400-411. doi: 10.1080/01480545.2022.2043351. [PMID: 35209778]
  • Michalina Zaborowska, Dorota Matyszewska, Renata Bilewicz. Model Lipid Raft Membranes for Embedding Integral Membrane Proteins: Reconstitution of HMG-CoA Reductase and Its Inhibition by Statins. Langmuir : the ACS journal of surfaces and colloids. 2022 11; 38(45):13888-13897. doi: 10.1021/acs.langmuir.2c02115. [PMID: 36335466]
  • Mohamed H Al-Sabri, Neha Behare, Ahmed M Alsehli, Samuel Berkins, Aadeya Arora, Eirini Antoniou, Eleni I Moysiadou, Sowmya Anantha-Krishnan, Patricia D Cosmen, Johanna Vikner, Thiago C Moulin, Nourhene Ammar, Hadi Boukhatmi, Laura E Clemensson, Mathias Rask-Andersen, Jessica Mwinyi, Michael J Williams, Robert Fredriksson, Helgi B Schiöth. Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes. Cells. 2022 11; 11(22):. doi: 10.3390/cells11223528. [PMID: 36428957]
  • Wenhao Wang, Fangqin Fu, Zhengwei Huang, Wenhua Wang, Minglong Chen, Xiao Yue, Jintao Fu, Xiaoqian Feng, Ying Huang, Chuanbin Wu, Xin Pan. Inhalable Biomimetic Protein Corona-Mediated Nanoreactor for Self-Amplified Lung Adenocarcinoma Ferroptosis Therapy. ACS nano. 2022 05; 16(5):8370-8387. doi: 10.1021/acsnano.2c02634. [PMID: 35575209]
  • Neeti Vashi, Cameron Ackerley, Martin Post, Monica J Justice. Aberrant lung lipids cause respiratory impairment in a Mecp2-deficient mouse model of Rett syndrome. Human molecular genetics. 2021 11; 30(22):2161-2176. doi: 10.1093/hmg/ddab182. [PMID: 34230964]
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  • Joseph Longo, Peter J Mullen, Rosemary Yu, Jenna E van Leeuwen, Mehdi Masoomian, Dixon T S Woon, Yuzhuo Wang, Eric X Chen, Robert J Hamilton, Joan M Sweet, Theodorus H van der Kwast, Neil E Fleshner, Linda Z Penn. An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer. Molecular metabolism. 2019 07; 25(?):119-130. doi: 10.1016/j.molmet.2019.04.003. [PMID: 31023626]
  • Leisan F Galiullina, Holger A Scheidt, Daniel Huster, Albert Aganov, Vladimir Klochkov. Interaction of statins with phospholipid bilayers studied by solid-state NMR spectroscopy. Biochimica et biophysica acta. Biomembranes. 2019 03; 1861(3):584-593. doi: 10.1016/j.bbamem.2018.12.013. [PMID: 30578770]
  • Qian Xiang, Xiaodan Zhang, Lingyue Ma, Kun Hu, Zhuo Zhang, Guangyan Mu, Qiufen Xie, Shuqing Chen, Yimin Cui. The association between the SLCO1B1, apolipoprotein E, and CYP2C9 genes and lipid response to fluvastatin: a meta-analysis. Pharmacogenetics and genomics. 2018 12; 28(12):261-267. doi: 10.1097/fpc.0000000000000356. [PMID: 30363031]
  • Yinzi Yue, Shuai Yan, Huan Li, Yang Zong, Jin Yue, Li Zeng. The role of oral fluvastatin on postoperative peritoneal adhesion formation in an experimental rat model. Acta chirurgica Belgica. 2018 Dec; 118(6):372-379. doi: 10.1080/00015458.2018.1444549. [PMID: 29482467]
  • Prasanthi Polamreddy, Vinita Vishwakarma, Puneet Saxena. Identification of potential anti-hepatitis C virus agents targeting non structural protein 5B using computational techniques. Journal of cellular biochemistry. 2018 11; 119(10):8574-8587. doi: 10.1002/jcb.27071. [PMID: 30058078]
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