2-Methoxystypandrone (BioDeep_00000021067)

human metabolite natural product

代谢物信息卡片

6-acetyl-5-hydroxy-2-methoxy-7-methyl-1,4-dihydronaphthalene-1,4-dione

化学式: C14H12O5 (260.0685)
中文名称:
谱图信息: 最多检出来源 Pteris henryi Christ(not specific) 6.25%

分子结构信息

SMILES: CC1=CC2=C(C(=O)C=C(C2=O)OC)C(=C1C(=O)C)O
InChI: InChI=1S/C14H12O5/c1-6-4-8-12(14(18)11(6)7(2)15)9(16)5-10(19-3)13(8)17/h4-5,18H,1-3H3

3D Structure

描述信息

2-Methoxystypandrone is found in green vegetables. 2-Methoxystypandrone is isolated from roots of Polygonum cuspidatum (Japanese knotweed).
Isolated from roots of Polygonum cuspidatum (Japanese knotweed). 2-Methoxystypandrone is found in green vegetables.

同义名列表

6 个代谢物同义名

6-acetyl-5-hydroxy-2-methoxy-7-methyl-1,4-dihydronaphthalene-1,4-dione; 6-acetyl-5-hydroxy-2-methoxy-7-methylnaphthalene-1,4-dione; 6-Acetyl-5-hydroxy-2-methoxy-7-methyl-1,4-naphthoquinone; 2-Methoxy-6-acethyl-7-methyljuglone; 2-Methoxy-6-acetyl-7-methyljuglone; 2-Methoxystypandrone

数据库引用编号

10 个数据库交叉引用编号

ChEBI: CHEBI:169725
PubChem: 158739
HMDB: HMDB0033265
ChEMBL: CHEMBL322776
KNApSAcK: C00050671
foodb: FDB011288
chemspider: 139638
CAS: 85122-21-0
PMhub: MS000055758
LOTUS: LTS0106925

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

27 个相关的物种来源信息

72167 - Berchemia: LTS0106925
72168 - Berchemia discolor: 10.1016/0031-9422(92)83730-M
72168 - Berchemia discolor: LTS0106925
2759 - Eukaryota: LTS0106925
3803 - Fabaceae: LTS0106925
76024 - Fallopia: LTS0106925
76025 - Fallopia multiflora: 10.1002/JEMT.20936
9606 - Homo sapiens: -
3398 - Magnoliopsida: LTS0106925
3615 - Polygonaceae: LTS0106925
655516 - Reynoutria: LTS0106925
488216 - Reynoutria japonica: LTS0106925
3608 - Rhamnaceae: LTS0106925
3618 - Rumex: LTS0106925
174651 - Rumex japonicus: 10.1021/JF00034A047
174651 - Rumex japonicus: LTS0106925
53922 - Senna: LTS0106925
72401 - Senna didymobotrya: 10.21608/BFSA.1988.73506
72401 - Senna didymobotrya: LTS0106925
2601745 - Senna longiracemosa: 10.1016/S0031-9422(00)95104-5
2601745 - Senna longiracemosa: LTS0106925
35493 - Streptophyta: LTS0106925
58023 - Tracheophyta: LTS0106925
106719 - Ventilago: LTS0106925
1390085 - Ventilago denticulata: 10.1016/S0031-9422(00)82557-1
1390085 - Ventilago denticulata: LTS0106925
33090 - Viridiplantae: LTS0106925

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表

文献列表

Yinda Qiu, Aoding Li, Jina Lee, Jeong Eun Lee, Eun-Woo Lee, Namki Cho, Hee Min Yoo. Inhibition of Jurkat T Cell Proliferation by Active Components of Rumex japonicus Roots Via Induced Mitochondrial Damage and Apoptosis Promotion. Journal of microbiology and biotechnology. 2020 Dec; 30(12):1885-1895. doi: 10.4014/jmb.2007.07018. [PMID: 33144550]
Shan Kuang, Chunting Qi, Jiawei Liu, Xiaoxiao Sun, Qing Zhang, Zhenhua Sima, Jingli Liu, Wuguo Li, Qiang Yu. 2-Methoxystypandrone inhibits signal transducer and activator of transcription 3 and nuclear factor-κB signaling by inhibiting Janus kinase 2 and IκB kinase. Cancer science. 2014 Apr; 105(4):473-80. doi: 10.1111/cas.12359. [PMID: 24450414]
Jiawei Liu, Qing Zhang, Kaotang Chen, Jingli Liu, Shan Kuang, Weiwen Chen, Qiang Yu. Small-molecule STAT3 signaling pathway modulators from Polygonum cuspidatum. Planta medica. 2012 Sep; 78(14):1568-70. doi: 10.1055/s-0032-1315121. [PMID: 22855270]