Isonicotinamide (BioDeep_00001868527)

Main id: BioDeep_00000003459

 


代谢物信息卡片


Isonicotinamide

化学式: C6H6N2O (122.048)
中文名称: 异烟碱, 4-吡啶甲酰胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CN=CC=C1C(=O)N
InChI: InChI=1S/C6H6N2O/c7-6(9)5-1-3-8-4-2-5/h1-4H,(H2,7,9)

描述信息

同义名列表

3 个代谢物同义名

Isonicotinamide; Isonicotineamide; 4-Pyridinecarboxamide



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 AKT1, CASP1, CASP3, CDK16, ELANE, HCFC1R1, PCK1, PMP2, PPARG, SIRT1, XDH
Peripheral membrane protein 2 ACHE, CDK16
Nucleus 10 ACHE, ADK, AKT1, CASP3, CDK16, HCFC1R1, JUND, PMP2, PPARG, SIRT1
cytosol 12 ADK, AKT1, CASP1, CASP3, CDK16, EHHADH, ELANE, PCK1, PMP2, PPARG, SIRT1, XDH
phagocytic vesicle 1 ELANE
nucleoplasm 7 ADK, AKT1, CASP3, HCFC1R1, JUND, PPARG, SIRT1
RNA polymerase II transcription regulator complex 2 JUND, PPARG
Cell membrane 5 ACHE, AKT1, CALHM6, CASP1, CDK16
Cytoplasmic side 1 CDK16
lamellipodium 1 AKT1
Multi-pass membrane protein 2 ATP4A, CALHM6
Synapse 1 ACHE
cell cortex 1 AKT1
cell surface 2 ACHE, ELANE
glutamatergic synapse 2 AKT1, CASP3
Golgi apparatus 1 ACHE
Golgi membrane 1 INS
neuromuscular junction 1 ACHE
neuronal cell body 2 CASP3, INHA
postsynapse 1 AKT1
synaptic vesicle 1 CDK16
Cytoplasm, cytosol 1 PCK1
Cytoplasmic vesicle, secretory vesicle 1 CDK16
plasma membrane 7 ACHE, ADK, AKT1, ATP4A, CALHM6, CASP1, CDK16
Membrane 4 ACHE, AKT1, ATP4A, CALHM6
apical plasma membrane 1 ATP4A
extracellular exosome 3 ELANE, PCK1, PMP2
endoplasmic reticulum 1 PCK1
extracellular space 7 ACHE, ATP4A, CCL4, ELANE, INHA, INS, XDH
perinuclear region of cytoplasm 2 ACHE, PPARG
mitochondrion 1 SIRT1
protein-containing complex 2 AKT1, CASP1
intracellular membrane-bounded organelle 1 PPARG
postsynaptic density 1 CASP3
chromatin silencing complex 1 SIRT1
Secreted 3 ACHE, INHA, INS
extracellular region 5 ACHE, CCL4, ELANE, INHA, INS
cytoplasmic side of plasma membrane 1 CDK16
Extracellular side 1 ACHE
transcription regulator complex 1 JUND
photoreceptor inner segment 1 INHA
photoreceptor outer segment 1 INHA
microtubule cytoskeleton 2 AKT1, CDK16
nucleolus 2 CASP1, SIRT1
cell-cell junction 1 AKT1
vesicle 1 AKT1
Apical cell membrane 1 ATP4A
heterochromatin 1 SIRT1
microtubule 1 CASP1
spindle 1 AKT1
Peroxisome 2 EHHADH, XDH
basement membrane 1 ACHE
sarcoplasmic reticulum 1 XDH
peroxisomal matrix 1 EHHADH
Nucleus, PML body 1 SIRT1
PML body 1 SIRT1
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
collagen-containing extracellular matrix 1 ELANE
secretory granule 1 ELANE
NLRP3 inflammasome complex 1 CASP1
nuclear inner membrane 1 SIRT1
receptor complex 1 PPARG
neuron projection 1 CDK16
ciliary basal body 1 AKT1
chromatin 3 JUND, PPARG, SIRT1
inhibin A complex 1 INHA
Lipid-anchor, GPI-anchor 1 ACHE
fibrillar center 1 SIRT1
nuclear envelope 1 SIRT1
endosome lumen 1 INS
euchromatin 1 SIRT1
side of membrane 1 ACHE
myelin sheath 1 PMP2
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 1 INS
transcription repressor complex 2 ELANE, JUND
specific granule lumen 1 ELANE
transport vesicle 1 INS
azurophil granule lumen 1 ELANE
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 CALHM6
[Isoform 2]: Cytoplasm 1 ADK
AIM2 inflammasome complex 1 CASP1
[Isoform 1]: Nucleus 1 ADK
Synapse, synaptosome 1 CDK16
synaptic cleft 1 ACHE
death-inducing signaling complex 1 CASP3
canonical inflammasome complex 1 CASP1
eNoSc complex 1 SIRT1
rDNA heterochromatin 1 SIRT1
Cytoplasmic vesicle, phagosome 1 ELANE
cyclin-dependent protein kinase holoenzyme complex 1 CDK16
transcription factor AP-1 complex 1 JUND
inhibin B complex 1 INHA
inhibin-betaglycan-ActRII complex 1 INHA
potassium:proton exchanging ATPase complex 1 ATP4A
[Isoform H]: Cell membrane 1 ACHE
IPAF inflammasome complex 1 CASP1
NLRP1 inflammasome complex 1 CASP1
protease inhibitor complex 1 CASP1
[SirtT1 75 kDa fragment]: Cytoplasm 1 SIRT1


文献列表

  • Wenxia Cui, Zehui He, Yongtai Zhang, Qiangyuan Fan, Nianping Feng. Naringenin Cocrystals Prepared by Solution Crystallization Method for Improving Bioavailability and Anti-hyperlipidemia Effects. AAPS PharmSciTech. 2019 Feb; 20(3):115. doi: 10.1208/s12249-019-1324-0. [PMID: 30771018]
  • Chao Hong, Yan Xie, Yashu Yao, Guowen Li, Xiurong Yuan, Hongyi Shen. A novel strategy for pharmaceutical cocrystal generation without knowledge of stoichiometric ratio: myricetin cocrystals and a ternary phase diagram. Pharmaceutical research. 2015 Jan; 32(1):47-60. doi: 10.1007/s11095-014-1443-y. [PMID: 24939640]
  • Frederike Ambagtsheer, Damián Zaitch, René van Swaaningen, Wilma Duijst, Willij Zuidema, Willem Weimar. Cross-border quest: the reality and legality of transplant tourism. Journal of transplantation. 2012; 2012(?):391936. doi: 10.1155/2012/391936. [PMID: 22655168]
  • Adam J Smith, Padmini Kavuru, Lukasz Wojtas, Michael J Zaworotko, R Douglas Shytle. Cocrystals of quercetin with improved solubility and oral bioavailability. Molecular pharmaceutics. 2011 Oct; 8(5):1867-76. doi: 10.1021/mp200209j. [PMID: 21846121]
  • Alan R Watson, Paul Harden, Maria Ferris, Peter G Kerr, John Mahan, Maher Fouad Ramzy. Transition from pediatric to adult renal services: a consensus statement by the International Society of Nephrology (ISN) and the International Pediatric Nephrology Association (IPNA). Pediatric nephrology (Berlin, Germany). 2011 Oct; 26(10):1753-7. doi: 10.1007/s00467-011-1981-z. [PMID: 21842231]
  • Alan R Watson, Paul N Harden, Maria E Ferris, Peter G Kerr, John D Mahan, Maher Fouad Ramzy. Transition from pediatric to adult renal services: a consensus statement by the International Society of Nephrology (ISN) and the International Pediatric Nephrology Association (IPNA). Kidney international. 2011 Oct; 80(7):704-7. doi: 10.1038/ki.2011.209. [PMID: 21832978]
  • Ulf Panzer, Jan-Eric Turner, Oliver M Steinmetz, Christian Kurts, Richard J Johnson, Rolf A K Stahl. ISN Forefronts Symposium 2010 in Sylt, Germany: 'Induction and Resolution of Renal Inflammation'. Kidney international. 2011 Apr; 79(8):807-13. doi: 10.1038/ki.2010.560. [PMID: 21289596]
  • R Vanholder, D Borniche, S Claus, R Correa-Rotter, R Crestani, M C Ferir, N Gibney, A Hurtado, V A Luyckx, D Portilla, S Rodriguez, M S Sever, J Vanmassenhove, R Wainstein. When the earth trembles in the Americas: the experience of Haiti and Chile 2010. Nephron. Clinical practice. 2011; 117(3):c184-97. doi: 10.1159/000320200. [PMID: 20805691]
  • Christina M Yuan, Robert M Perkins. Renal replacement therapy in austere environments. International journal of nephrology. 2011; 2011(?):748053. doi: 10.4061/2011/748053. [PMID: 21603109]
  • Shuying Huo, Zhihao Xu, Xiaoxin Zhang, Jianfang Zhang, Sheng Cui. Testicular denervation in prepuberty rat inhibits seminiferous tubule development and spermatogenesis. The Journal of reproduction and development. 2010 Aug; 56(4):370-8. doi: 10.1262/jrd.10-009n. [PMID: 20424380]
  • Devita Surjana, Gary M Halliday, Diona L Damian. Role of nicotinamide in DNA damage, mutagenesis, and DNA repair. Journal of nucleic acids. 2010 Jul; 2010(?):. doi: 10.4061/2010/157591. [PMID: 20725615]
  • Kui Wang, Lu Liu, Wei Li, Da-zhuo Shi, Wen-ying Zeng, Mian-sheng Zhu, Michel Angles, Jean-Raymond Attali, Pedro Choy, Joao Choy, Chi-haur Wu, Fu-han Zhai, Maria Calduch Ramon, Ching Chung. Study on international standard multilingual nomenclature of Chinese medicine. Chinese journal of integrative medicine. 2010 Apr; 16(2):176-9. doi: 10.1007/s11655-010-0176-y. [PMID: 20473746]
  • Guillermo Garcia-Garcia, Isela Marquez-Magaña, Karina Renoirte-Lopez, Gustavo Perez-Cortes, M Luisa Salazar Gutierrez, Scott Klarenbach, Anita Lloyd, Marcello Tonelli. Screening for kidney disease on World Kidney Day in Jalisco, Mexico. Journal of nephrology. 2010 Mar; 23(2):224-30. doi: NULL. [PMID: 20119929]
  • Gabriel Richet. Francophone clinical nephrology from 1945 to 1960. Journal of nephrology. 2009 Nov; 22 Suppl 14(?):129-35. doi: NULL. [PMID: 20013745]
  • Yusuke Tsukamoto, HaiYan Wang, Gavin Becker, Hung-Chun Chen, Dae-Suk Han, David Harris, Enyu Imai, Vivekanand Jha, Philip K T Li, Evan J C Lee, Seiichi Matsuo, Yasuhiko Tomino, Kriang Tungsanga, Kunihiro Yamagata, Akira Hishida. Report of the Asian Forum of Chronic Kidney Disease Initiative (AFCKDI) 2007. 'Current status and perspective of CKD in Asia': diversity and specificity among Asian countries. Clinical and experimental nephrology. 2009 Jun; 13(3):249-56. doi: 10.1007/s10157-009-0156-8. [PMID: 19288169]
  • Ravindra L Mehta, John A Kellum, Sudhir V Shah, Bruce A Molitoris, Claudio Ronco, David G Warnock, Adeera Levin. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Critical care (London, England). 2007; 11(2):R31. doi: 10.1186/cc5713. [PMID: 17331245]
  • R Vanholder, A van der Tol, M De Smet, E Hoste, M Koç, A Hussain, S Khan, M S Sever. Earthquakes and crush syndrome casualties: lessons learned from the Kashmir disaster. Kidney international. 2007 Jan; 71(1):17-23. doi: 10.1038/sj.ki.5001956. [PMID: 17063177]
  • Melvin M Schwartz. The pathology of lupus nephritis. Seminars in nephrology. 2007 Jan; 27(1):22-34. doi: 10.1016/j.semnephrol.2006.09.005. [PMID: 17336686]
  • Carl-Magnus Bäckesjö, Yan Li, Urban Lindgren, Lars-Arne Haldosén. Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2006 Jul; 21(7):993-1002. doi: 10.1359/jbmr.060415. [PMID: 16813520]
  • Bolesław Rutkowski. Contribution of Central and Eastern Europe (CEE) to Nephrology. Journal of nephrology. 2006 May; 19 Suppl 10(?):S165-72. doi: NULL. [PMID: 16874732]
  • Ebun L Bamgboye. End-stage renal disease in sub-Saharan Africa. Ethnicity & disease. 2006; 16(2 Suppl 2):S2-5. doi: NULL. [PMID: 16774001]
  • Philip Kam-Tao Li, Jan J Weening, John Dirks, Sing Leung Lui, Cheuk Chun Szeto, Sydney Tang, Robert C Atkins, William E Mitch, Kai Ming Chow, Giuseppe D'Amico, Barry I Freedman, David C Harris, Lai-Seong Hooi, Paul E de Jong, Priscilla Kincaid-Smith, Kar Neng Lai, Evan Lee, Fu-Keung Li, Shan-Yan Lin, Wai-Kei Lo, M K Mani, Timothy Mathew, Mutsumi Murakami, Jia-Qi Qian, Sylvia Ramirez, Thomas Reiser, Yasuhiko Tomino, Matthew K Tong, Wai-Kay Tsang, Kriang Tungsanga, Haiyan Wang, Andrew K Wong, Kim Ming Wong, Wu-Chang Yang, Dick de Zeeuw, Alex W Yu, Giuseppe Remuzzi. A report with consensus statements of the International Society of Nephrology 2004 Consensus Workshop on Prevention of Progression of Renal Disease, Hong Kong, June 29, 2004. Kidney international. Supplement. 2005 Apr; ?(94):S2-7. doi: 10.1111/j.1523-1755.2005.09401.x. [PMID: 15752234]
  • Sergey Osinsky, Ilia Levitin, Larissa Bubnovskaya, Andrey Sigan, Irina Ganusevich, Antonina Kovelskaya, Natalya Valkovskaya, Luigi Campanella, Peter Wardman. Selectivity of effects of redox-active cobalt(III) complexes on tumor tissue. Experimental oncology. 2004 Jun; 26(2):140-4. doi: . [PMID: 15273664]
  • R Vanholder, M S Sever, M De Smet, E Erek, N Lameire. Intervention of the Renal Disaster Relief Task Force in the 1999 Marmara, Turkey earthquake. Kidney international. 2001 Feb; 59(2):783-91. doi: 10.1046/j.1523-1755.2001.059002783.x. [PMID: 11168962]
  • T Kawabata, T Ogino, M Mori, M Awai. Effects of nicotinamide and its isomers on iron-induced renal damage. Acta pathologica japonica. 1992 Jul; 42(7):469-75. doi: 10.1111/j.1440-1827.1992.tb03091.x. [PMID: 1414356]
  • L Giuliani, G Carmignani, E Belgrano, P Puppo. Transcatheter arterial embolization in urological tumors: the use of isobutyl-2-cyanoacrylate. The Journal of urology. 1979 May; 121(5):630-4. doi: 10.1016/s0022-5347(17)56913-x. [PMID: 439260]