PHENYLHYDRAZINE (BioDeep_00001867810)
Main id: BioDeep_00000004147
PANOMIX_OTCML-2023
代谢物信息卡片
PHENYLHYDRAZINE
化学式: C6H8N2 (108.0687)
中文名称: 苯肼
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C(C=C1)NN
InChI: InChI=1S/C6H8N2/c7-8-6-4-2-1-3-5-6/h1-5,8H,7H2
描述信息
D009676 - Noxae > D016877 - Oxidants
同义名列表
3 个代谢物同义名
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:27924
- KEGG: C02304
- PubChem: 7516
- ChEMBL: CHEMBL456807
- CAS: 125687-18-5
- CAS: 100-63-0
- PubChem: 5358
- PDB-CCD: PHZ
- NIKKAJI: J38.250G
- RefMet: Phenylhydrazine
- KNApSAcK: 27924
分类词条
相关代谢途径
Reactome(0)
BioCyc(16)
- allantoin degradation to ureidoglycolate II (ammonia producing)
- allantoin degradation to glyoxylate III
- superpathway of anaerobic energy metabolism (invertebrates)
- superpathway of allantoin degradation in plants
- superpathway of polyamine biosynthesis I
- superpathway of arginine and polyamine biosynthesis
- L-arginine degradation VIII (arginine oxidase pathway)
- superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation
- L-arginine degradation XI
- superpathway of L-arginine and L-ornithine degradation
- formaldehyde assimilation I (serine pathway)
- superpathway of L-lysine degradation
- L-lysine fermentation to acetate and butanoate
- spermidine biosynthesis I
- anaerobic energy metabolism (invertebrates, cytosol)
- trans-4-hydroxy-L-proline degradation I
PlantCyc(3)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Gbenga Sunday Adeleye, E O Odesanmi, Kazeem O Ajeigbe, Tosan Omayone, Anthony Odetola, A Omolara Sobanke. Ameliorative Effects of Coconut Water on Hematological and Lipid Profiles of Phenylhydrazine-treated Rats.
Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria.
2023 Dec; 38(2):255-264. doi:
10.54548/njps.v38i2.15. [PMID: 38696690] - Azubuike Ikechukwu Okafor, Cecilia Ushike Atsu. Ficus glumosa Del. reduces phenylhydrazine-induced hemolytic anaemia and hepatic damage in Wistar rats.
Journal of complementary & integrative medicine.
2022 Sep; 19(3):661-668. doi:
10.1515/jcim-2021-0306. [PMID: 35106983] - Hong-Qian Wang, Er-Liang Kong, Xia Zhang, Xiao-Yan Meng, Jin-Min Zhang, Wei-Feng Yu, Fei-Xiang Wu. Folic acid alleviates jaundice of phenylhydrazine (PHA)-induced neonatal rats by reducing Lys-homocysteinylation of albumin.
Cell biology and toxicology.
2021 10; 37(5):679-693. doi:
10.1007/s10565-021-09602-3. [PMID: 33788065] - Rui-Jia Fu, Wen-Xiao Wang, Hui-Juan Tao, Mei Wang, Yan-Yan Chen, Huan Gao, Shi-Jun Yue, Yu-Ping Tang. Quantitative evaluation of Danqi tablet by ultra-performance liquid chromatography coupled with triple quadrupole mass spectrometry integrated with bioassay.
Journal of separation science.
2021 Apr; 44(7):1552-1563. doi:
10.1002/jssc.202000932. [PMID: 33475238] - Jui-Chung Chiang, Wei-Min Chen, Kuan-Hung Lin, Kai Hsia, Ya-Hsuan Ho, Yueh-Chien Lin, Tang-Long Shen, Jen-Her Lu, Shih-Kuo Chen, Chao-Ling Yao, Benjamin P C Chen, Hsinyu Lee. Lysophosphatidic acid receptors 2 and 3 regulate erythropoiesis at different hematopoietic stages.
Biochimica et biophysica acta. Molecular and cell biology of lipids.
2021 01; 1866(1):158818. doi:
10.1016/j.bbalip.2020.158818. [PMID: 33035680] - Yen-Hua Chen, Sen-Shyong Jeng, Ya-Chia Hsu, Yu-Min Liao, Yu-Xin Wang, Xia Cao, Lian-Jiang Huang. In anemia zinc is recruited from bone and plasma to produce new red blood cells.
Journal of inorganic biochemistry.
2020 09; 210(?):111172. doi:
10.1016/j.jinorgbio.2020.111172. [PMID: 32659518] - Nicolas S Merle, Juliette Leon, Victoria Poillerat, Anne Grunenwald, Idris Boudhabhay, Samantha Knockaert, Tania Robe-Rybkine, Carine Torset, Matthew C Pickering, Sophie Chauvet, Veronique Fremeaux-Bacchi, Lubka T Roumenina. Circulating FH Protects Kidneys From Tubular Injury During Systemic Hemolysis.
Frontiers in immunology.
2020; 11(?):1772. doi:
10.3389/fimmu.2020.01772. [PMID: 32849636] - Blessing Nkazimulo Mkhwanazi, Fanie Retief van Heerden, Greanious Alfred Mavondo, Musa Vuyisile Mabandla, Cephas Tagumirwa Musabayane. Triterpene derivative improves the renal function of streptozotocin-induced diabetic rats: a follow-up study on maslinic acid.
Renal failure.
2019 Nov; 41(1):547-554. doi:
10.1080/0886022x.2019.1623818. [PMID: 31234683] - Su Jung Park, Sam Seok Cho, Kyu Min Kim, Ji Hye Yang, Jae Hoon Kim, Eun Hee Jeong, Jin Won Yang, Chang Yeob Han, Sae Kwang Ku, Il Je Cho, Sung Hwan Ki. Protective effect of sestrin2 against iron overload and ferroptosis-induced liver injury.
Toxicology and applied pharmacology.
2019 09; 379(?):114665. doi:
10.1016/j.taap.2019.114665. [PMID: 31323261] - A Bhasym, G K Annarapu, S Saha, N Shrimali, S Gupta, T Seth, P Guchhait. Neutrophils develop rapid proinflammatory response after engulfing Hb-activated platelets under intravascular hemolysis.
Clinical and experimental immunology.
2019 08; 197(2):131-140. doi:
10.1111/cei.13310. [PMID: 31099890] - Rankaljeet Kaur, Preety Ghanghas, Pulkit Rastogi, Naveen Kaushal. Protective Role of Selenium Against Hemolytic Anemia Is Mediated Through Redox Modulation.
Biological trace element research.
2019 Jun; 189(2):490-500. doi:
10.1007/s12011-018-1483-y. [PMID: 30151563] - Nicolas S Merle, Romain Paule, Juliette Leon, Marie Daugan, Tania Robe-Rybkine, Victoria Poillerat, Carine Torset, Véronique Frémeaux-Bacchi, Jordan D Dimitrov, Lubka T Roumenina. P-selectin drives complement attack on endothelium during intravascular hemolysis in TLR-4/heme-dependent manner.
Proceedings of the National Academy of Sciences of the United States of America.
2019 03; 116(13):6280-6285. doi:
10.1073/pnas.1814797116. [PMID: 30850533] - Ji Hye Yang, Moon-Hee Choi, Chang-Su Na, Sam Seok Cho, Jae Hoon Kim, Sae Kwang Ku, Il Je Cho, Hyun-Jae Shin, Sung Hwan Ki. Bamboo Stems (Phyllostachys nigra variety henosis) Containing Polyphenol Mixtures Activate Nrf2 and Attenuate Phenylhydrazine-Induced Oxidative Stress and Liver Injury.
Nutrients.
2019 Jan; 11(1):. doi:
10.3390/nu11010114. [PMID: 30626086] - Fabio Henrique Silva, Kleber Yotsumoto Fertrin, Eduardo Costa Alexandre, Fabiano Beraldi Calmasini, Carla Fernanda Franco-Penteado, Fernando Ferreira Costa. Impairment of Nitric Oxide Pathway by Intravascular Hemolysis Plays a Major Role in Mice Esophageal Hypercontractility: Reversion by Soluble Guanylyl Cyclase Stimulator.
The Journal of pharmacology and experimental therapeutics.
2018 11; 367(2):194-202. doi:
10.1124/jpet.118.249581. [PMID: 30108160] - Lu Xiaoyan, Chen Li, Ting Liu, Han Ke, Xingchu Gong, Qingqing Wang, Jianbing Zhang, Xiaohui Fan. Chemical analysis, pharmacological activity and process optimization of the proportion of bilobalide and ginkgolides in Ginkgo biloba extract.
Journal of pharmaceutical and biomedical analysis.
2018 Oct; 160(?):46-54. doi:
10.1016/j.jpba.2018.07.037. [PMID: 30071391] - I Gheith, A El-Mahmoudy. Laboratory evidence for the hematopoietic potential of Beta vulgaris leaf and stalk extract in a phenylhydrazine model of anemia.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
2018 Oct; 51(11):e7722. doi:
10.1590/1414-431x20187722. [PMID: 30328935] - Hojat Anbara, Rasoul Shahrooz, Mazdak Razi, Hassan Malekinejad, Gholamreza Najafi. The effect of vitamin C on mice hemolytic anemia induced by phenylhydrazine: an animal model study using histological changes in testis, pre-implantation embryo development, and biochemical changes.
Iranian journal of basic medical sciences.
2018 Jul; 21(7):668-677. doi:
10.22038/ijbms.2018.25819.6356. [PMID: 30140404] - Temitayo Olabisi Ajibade, Ademola Adetokunbo Oyagbemi, Temidayo Olutayo Omobowale, Ebunoluwa Rachael Asenuga, Adebowale Bernard Saba. Telferia Occidentalis and Vitamin C Attenuate Phenylhydrazine-Induced Haemolytic Anaemia and Associated Cardio-renal Dysfunctions via Inhibition of Oxidative Stress and Proapoptotic -Protein (Bax) Expressions.
Drug research.
2018 02; 68(2):104-112. doi:
10.1055/s-0043-119070. [PMID: 28926854] - Peng Ji, Yanming Wei, Yongli Hua, Xiaosong Zhang, Wanling Yao, Qi Ma, Ziwen Yuan, Yanqiao Wen, Chaoxue Yang. A novel approach using metabolomics coupled with hematological and biochemical parameters to explain the enriching-blood effect and mechanism of unprocessed Angelica sinensis and its 4 kinds of processed products.
Journal of ethnopharmacology.
2018 Jan; 211(?):101-116. doi:
10.1016/j.jep.2017.09.028. [PMID: 28958590] - Nicolas S Merle, Anne Grunenwald, Marie-Lucile Figueres, Sophie Chauvet, Marie Daugan, Samantha Knockaert, Tania Robe-Rybkine, Remi Noe, Olivia May, Marie Frimat, Nathan Brinkman, Thomas Gentinetta, Sylvia Miescher, Pascal Houillier, Veronique Legros, Florence Gonnet, Olivier P Blanc-Brude, Marion Rabant, Regis Daniel, Jordan D Dimitrov, Lubka T Roumenina. Characterization of Renal Injury and Inflammation in an Experimental Model of Intravascular Hemolysis.
Frontiers in immunology.
2018; 9(?):179. doi:
10.3389/fimmu.2018.00179. [PMID: 29545789] - Nirmalya Bandyopadhyay, Ankur Bikash Pradhan, Suman Das, Jnan Prakash Naskar. Comparative study of an osazone based ligand and its palladium(II) complex with human serum albumin: A spectroscopic, thermodynamic and molecular docking approach.
Journal of photochemistry and photobiology. B, Biology.
2017 Aug; 173(?):1-11. doi:
10.1016/j.jphotobiol.2017.05.025. [PMID: 28554071] - Chimaraoke Onyeabo, Ngozi K Achi, Chima A Ekeleme-Egedigwe, Chidinma U Ebere, Chidinma K Okoro. Haematological and biochemical studies on Justicia carnea leaves extract in phenylhydrazine induced-anemia in albino rats.
Acta scientiarum polonorum. Technologia alimentaria.
2017 Apr; 16(2):217-230. doi:
10.17306/j.afs.0492. [PMID: 28703962] - Temitayo Olabisi Ajibade, Ademola Adetokunbo Oyagbemi, Ladoke A Durotoye, Temidayo Olutayo Omóbòwálé, Ebunoluwa Racheal Asenuga, Funsho Olakitike Olayemi. Modulatory effects of melatonin and vitamin C on oxidative stress-mediated haemolytic anaemia and associated cardiovascular dysfunctions in rats.
Journal of complementary & integrative medicine.
2017 Mar; 14(1):. doi:
10.1515/jcim-2015-0082. [PMID: 28237973] - Cornel S G Mirciov, Sarah J Wilkins, Linda A Dunn, Gregory J Anderson, David M Frazer. Characterization of Putative Erythroid Regulators of Hepcidin in Mouse Models of Anemia.
PloS one.
2017; 12(1):e0171054. doi:
10.1371/journal.pone.0171054. [PMID: 28135344] - Haq Nawaz, Muhammad Aslam Shad, Mohammad Saeed Iqbal. Optimization of phenylhydrazine induced hyperbilirubinemia in experimental rabbit.
Experimental animals.
2016 Nov; 65(4):363-372. doi:
10.1538/expanim.16-0011. [PMID: 27210076] - Stuti Pandey, Aditya Ganeshpurkar, Divya Bansal, Nazneen Dubey. Hematopoietic Effect of Amaranthus cruentus Extract on Phenylhydrazine-Induced Toxicity in Rats.
Journal of dietary supplements.
2016 Nov; 13(6):607-15. doi:
10.3109/19390211.2016.1155685. [PMID: 27027824] - Xingkang Jiang, Ming Gao, Yue Chen, Jing Liu, Shiyong Qi, Juan Ma, Zhihong Zhang, Yong Xu. EPO-dependent induction of erythroferrone drives hepcidin suppression and systematic iron absorption under phenylhydrazine-induced hemolytic anemia.
Blood cells, molecules & diseases.
2016 May; 58(?):45-51. doi:
10.1016/j.bcmd.2016.02.005. [PMID: 27067488] - Chandra Sekhar Misra, Chethan Gejjalagere Honnappa, Srinivas Reddy Jitta, Karthik Gourishetti, Prasanthi Daram, Mahendra Pal Singh, Akhila Hosur Shrungeswara, Yogendra Nayak, Mazhuvancherry Kesavan Unnikrishnan. Biological activity of a small molecule indole analog, 1-[(1H-indol-3-yl)methylene]-2-phenylhydrazine (HMPH), in chronic inflammation.
Chemico-biological interactions.
2016 Jan; 244(?):71-83. doi:
10.1016/j.cbi.2015.10.024. [PMID: 26549477] - Rupali Arun Patil, Aakash B Makwana. Anti-hyperbilirubinemic and wound healing activity of aqueous extract of Calotropis procera leaves in Wistar rats.
Indian journal of pharmacology.
2015 Jul; 47(4):398-402. doi:
10.4103/0253-7613.161262. [PMID: 26288472] - Richa Chaturvedi, Pronobesh Chattopadhyay, Saumen Banerjee, Chira R Bhattacharjee, Prasanta Raul, Kusum Borah, Lokendra Singh, Vijay Veer. Iron-rich drinking water and ascorbic acid supplementation improved hemolytic anemia in experimental Wistar rats.
International journal of food sciences and nutrition.
2014 Nov; 65(7):856-61. doi:
10.3109/09637486.2014.918589. [PMID: 24896300] - Weixia Li, Yuping Tang, Jianming Guo, Erxin Shang, Yefei Qian, Linyan Wang, Li Zhang, Pei Liu, Shulan Su, Dawei Qian, Jin-ao Duan. Comparative metabolomics analysis on hematopoietic functions of herb pair Gui-Xiong by ultra-high-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry and pattern recognition approach.
Journal of chromatography. A.
2014 Jun; 1346(?):49-56. doi:
10.1016/j.chroma.2014.04.042. [PMID: 24794940] - Francesca Vinchi, Giada Ingoglia, Deborah Chiabrando, Sonia Mercurio, Emilia Turco, Lorenzo Silengo, Fiorella Altruda, Emanuela Tolosano. Heme exporter FLVCR1a regulates heme synthesis and degradation and controls activity of cytochromes P450.
Gastroenterology.
2014 May; 146(5):1325-38. doi:
10.1053/j.gastro.2014.01.053. [PMID: 24486949] - Yusof Kamisah, Jing Jye Lim, Chew-Lian Lim, Ahmad Y Asmadi. Inhibitory effects of palm tocotrienol-rich fraction supplementation on bilirubin-metabolizing enzymes in hyperbilirubinemic adult rats.
PloS one.
2014; 9(2):e89248. doi:
10.1371/journal.pone.0089248. [PMID: 24586630] - Koki Harigaya, Hiroyuki Yamada, Shingo Horimoto, Hiroyuki Nishi, Jun Haginaka. Sensitive quantitation of residual phenylhydrazine in antipyrine by LC-ICP-MS with iodo derivatization.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
2014; 30(8):845-50. doi:
10.2116/analsci.30.845. [PMID: 25109648] - Hye Won Lee, Hyojun Kim, Jin Ah Ryuk, Ki-Jung Kil, Byoung Seob Ko. Hemopoietic effect of extracts from constituent herbal medicines of Samul-tang on phenylhydrazine-induced hemolytic anemia in rats.
International journal of clinical and experimental pathology.
2014; 7(9):6179-85. doi:
". [PMID: 25337267] - Andrea B Schreuder, Ann C Rice, Jana Vanikova, Libor Vitek, Steven M Shapiro, Henkjan J Verkade. Albumin administration protects against bilirubin-induced auditory brainstem dysfunction in Gunn rat pups.
Liver international : official journal of the International Association for the Study of the Liver.
2013 Nov; 33(10):1557-65. doi:
10.1111/liv.12219. [PMID: 23742048] - M Föller, I S Harris, A Elia, R John, F Lang, T J Kavanagh, T W Mak. Functional significance of glutamate-cysteine ligase modifier for erythrocyte survival in vitro and in vivo.
Cell death and differentiation.
2013 Oct; 20(10):1350-8. doi:
10.1038/cdd.2013.70. [PMID: 23787995] - Boualem Moulouel, Dounia Houamel, Constance Delaby, Dimitri Tchernitchko, Sophie Vaulont, Philippe Letteron, Olivier Thibaudeau, Hervé Puy, Laurent Gouya, Carole Beaumont, Zoubida Karim. Hepcidin regulates intrarenal iron handling at the distal nephron.
Kidney international.
2013 Oct; 84(4):756-66. doi:
10.1038/ki.2013.142. [PMID: 23615502] - Soumya Maity, Nivedita Nag, Suchandra Chatterjee, Soumyakanti Adhikari, Santasree Mazumder. Bilirubin clearance and antioxidant activities of ethanol extract of Phyllanthus amarus root in phenylhydrazine-induced neonatal jaundice in mice.
Journal of physiology and biochemistry.
2013 Sep; 69(3):467-76. doi:
10.1007/s13105-013-0234-y. [PMID: 23318962] - Hiroko Sato, Tetsuya Sakairi, Hisako Fujimura, Jiro Sugimoto, Eisuke Kume, Kazuyuki Kitamura, Kimimasa Takahashi. Hematological and morphological investigation of thrombogenic mechanisms in the lungs of phenylhydrazine-treated rats.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2013 May; 65(4):457-62. doi:
10.1016/j.etp.2012.01.004. [PMID: 22402172] - Madelyn S Hanson, Hao Xu, Timothy C Flewelen, Sandra L Holzhauer, Dawn Retherford, Deron W Jones, Anne C Frei, Kirkwood A Pritchard, Cheryl A Hillery, Neil Hogg, Nancy J Wandersee. A novel hemoglobin-binding peptide reduces cell-free hemoglobin in murine hemolytic anemia.
American journal of physiology. Heart and circulatory physiology.
2013 Jan; 304(2):H328-36. doi:
10.1152/ajpheart.00500.2012. [PMID: 23125208] - Tetsuhiro Tanaka, Junna Yamaguchi, Kumi Shoji, Masaomi Nangaku. Anthracycline inhibits recruitment of hypoxia-inducible transcription factors and suppresses tumor cell migration and cardiac angiogenic response in the host.
The Journal of biological chemistry.
2012 Oct; 287(42):34866-34882. doi:
10.1074/jbc.m112.374587. [PMID: 22908232] - Sang Hun Lee, Hyung Joo Suh, Hyun-Sun Lee, Yooheon Park, Jang-Woo Park, Eun Young Jung. Hematopoietic effect of Bacillus subtilis-fermented antler extract on phenylhydrazine-induced hemolytic anemia in Sprague-Dawley rats.
Journal of medicinal food.
2012 Sep; 15(9):774-80. doi:
10.1089/jmf.2012.2264. [PMID: 22870931] - Patarabutr Masaratana, Gladys O Latunde-Dada, Neeta Patel, Robert J Simpson, Sophie Vaulont, Andrew T McKie. Iron metabolism in hepcidin1 knockout mice in response to phenylhydrazine-induced hemolysis.
Blood cells, molecules & diseases.
2012 Aug; 49(2):85-91. doi:
10.1016/j.bcmd.2012.04.003. [PMID: 22609087] - Shreesh Kumar Ojha, Saurabh Bharti, Sujata Joshi, Santosh Kumari, Dharamvir Singh Arya. Protective effect of hydroalcoholic extract of Andrographis paniculata on ischaemia-reperfusion induced myocardial injury in rats.
The Indian journal of medical research.
2012 Mar; 135(?):414-21. doi:
. [PMID: 22561631] - Muhammad Naveed Yousaf, Mark D Powell. The effects of heart and skeletal muscle inflammation and cardiomyopathy syndrome on creatine kinase and lactate dehydrogenase levels in Atlantic salmon (Salmo salar L.).
TheScientificWorldJournal.
2012; 2012(?):741302. doi:
10.1100/2012/741302. [PMID: 22701371] - Benedetta De Chiara, Valentina Sedda, Marina Parolini, Jonica Campolo, Renata De Maria, Raffaele Caruso, Gianluigi Pizzi, Olga Disoteo, Cinzia Dellanoce, Anna Rosa Corno, Giuliana Cighetti, Oberdan Parodi. Plasma total cysteine and cardiovascular risk burden: action and interaction.
TheScientificWorldJournal.
2012; 2012(?):303654. doi:
10.1100/2012/303654. [PMID: 22593672] - Katalin Kiss, Anna Brozik, Nora Kucsma, Alexandra Toth, Melinda Gera, Laurence Berry, Alice Vallentin, Henri Vial, Michel Vidal, Gergely Szakacs. Shifting the paradigm: the putative mitochondrial protein ABCB6 resides in the lysosomes of cells and in the plasma membrane of erythrocytes.
PloS one.
2012; 7(5):e37378. doi:
10.1371/journal.pone.0037378. [PMID: 22655043] - Weixia Li, Jianming Guo, Yuping Tang, Huan Wang, Meiyan Huang, Dawei Qian, Jin-Ao Duan. Pharmacokinetic comparison of ferulic acid in normal and blood deficiency rats after oral administration of Angelica sinensis, Ligusticum chuanxiong and their combination.
International journal of molecular sciences.
2012; 13(3):3583-97. doi:
10.3390/ijms13033583. [PMID: 22489169] - Denham G Cook, Rufus M G Wells, Neill A Herbert. Anaemia adjusts the aerobic physiology of snapper (Pagrus auratus) and modulates hypoxia avoidance behaviour during oxygen choice presentations.
The Journal of experimental biology.
2011 Sep; 214(Pt 17):2927-34. doi:
10.1242/jeb.057091. [PMID: 21832136] - Weixia Li, Yuping Tang, Jianming Guo, Meiyan Huang, Wei Li, Dawei Qian, Jin'ao Duan. [Enriching blood effect comparison in three kinds of blood deficiency model after oral administration of drug pair of Angelicae Sinensis Radix and Chuanxiong Rhizoma and each single herb].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2011 Jul; 36(13):1808-14. doi:
". [PMID: 22032150] - Mark D Powell, Melissa S Burke, Dalia Dahle. Cardiac remodelling, blood chemistry, haematology and oxygen consumption of Atlantic cod, Gadus morhua L., induced by experimental haemolytic anaemia with phenylhydrazine.
Fish physiology and biochemistry.
2011 Mar; 37(1):31-41. doi:
10.1007/s10695-010-9413-8. [PMID: 20585853] - Kazuhiko Nishimura, Haruna Nakaya, Hiroshi Nakagawa, Saburo Matsuo, Yoshihiro Ohnishi, Shinji Yamasaki. Effect of Trypanosoma brucei brucei on erythropoiesis in infected rats.
The Journal of parasitology.
2011 Feb; 97(1):88-93. doi:
10.1645/ge-2522.1. [PMID: 21348612] - Travis J Riedel, Lynnette C Johnson, John Knight, Roy R Hantgan, Ross P Holmes, W Todd Lowther. Structural and biochemical studies of human 4-hydroxy-2-oxoglutarate aldolase: implications for hydroxyproline metabolism in primary hyperoxaluria.
PloS one.
2011; 6(10):e26021. doi:
10.1371/journal.pone.0026021. [PMID: 21998747] - Xiaoqing Pan, Norio Suzuki, Ikuo Hirano, Shun Yamazaki, Naoko Minegishi, Masayuki Yamamoto. Isolation and characterization of renal erythropoietin-producing cells from genetically produced anemia mice.
PloS one.
2011; 6(10):e25839. doi:
10.1371/journal.pone.0025839. [PMID: 22022454] - Alfonso Muñoz, Gerard L Bannenberg, Olimpio Montero, Juan Miguel Cabello-Díaz, Pedro Piedras, Manuel Pineda. An alternative pathway for ureide usage in legumes: enzymatic formation of a ureidoglycolate adduct in Cicer arietinum and Phaseolus vulgaris.
Journal of experimental botany.
2011 Jan; 62(1):307-18. doi:
10.1093/jxb/erq268. [PMID: 20813786] - Govindjee, Dmitriy Shevela. Adventures with cyanobacteria: a personal perspective.
Frontiers in plant science.
2011; 2(?):28. doi:
10.3389/fpls.2011.00028. [PMID: 22645530] - Heung Bae Jeon, Yujin Jang. Reversible inactivation of bovine plasma amine oxidase by cysteamine and related analogs.
Biochemical and biophysical research communications.
2010 Dec; 403(3-4):442-6. doi:
10.1016/j.bbrc.2010.11.052. [PMID: 21094148] - A M Rojano-Delgado, F Priego-Capote, M D Luque de Castro, R De Prado. Screening and confirmatory analysis of glyoxylate: a biomarker of plants resistance against herbicides.
Talanta.
2010 Oct; 82(5):1757-62. doi:
10.1016/j.talanta.2010.07.068. [PMID: 20875573] - Ludovico Abenavoli, Raffaele Capasso, Natasa Milic, Francesco Capasso. Milk thistle in liver diseases: past, present, future.
Phytotherapy research : PTR.
2010 Oct; 24(10):1423-32. doi:
10.1002/ptr.3207. [PMID: 20564545] - Deepak Darshan, David M Frazer, Sarah J Wilkins, Gregory J Anderson. Severe iron deficiency blunts the response of the iron regulatory gene Hamp and pro-inflammatory cytokines to lipopolysaccharide.
Haematologica.
2010 Oct; 95(10):1660-7. doi:
10.3324/haematol.2010.022426. [PMID: 20511664] - Suresh Kumar Gupta, V Kalaiselvan, Sushma Srivastava, Shyam S Agrawal, Rohit Saxena. Evaluation of anticataract potential of Triphala in selenite-induced cataract: In vitro and in vivo studies.
Journal of Ayurveda and integrative medicine.
2010 Oct; 1(4):280-6. doi:
10.4103/0975-9476.74425. [PMID: 21731375] - Kimberly A Borley, Jody M Beers, Bruce D Sidell. Phenylhydrazine-induced anemia causes nitric-oxide-mediated upregulation of the angiogenic pathway in Notothenia coriiceps.
The Journal of experimental biology.
2010 Aug; 213(Pt 16):2865-72. doi:
10.1242/jeb.043281. [PMID: 20675556] - Yasuhito Shirai, Takeshi Kouzuki, Kenichi Kakefuda, Shigeki Moriguchi, Atsushi Oyagi, Kyoji Horie, Shin-ya Morita, Masamitsu Shimazawa, Kohji Fukunaga, Junji Takeda, Naoaki Saito, Hideaki Hara. Essential role of neuron-enriched diacylglycerol kinase (DGK), DGKbeta in neurite spine formation, contributing to cognitive function.
PloS one.
2010 Jul; 5(7):e11602. doi:
10.1371/journal.pone.0011602. [PMID: 20657643] - Shaobin Wang, George L Dale, Ping Song, Benoit Viollet, Ming-Hui Zou. AMPKalpha1 deletion shortens erythrocyte life span in mice: role of oxidative stress.
The Journal of biological chemistry.
2010 Jun; 285(26):19976-85. doi:
10.1074/jbc.m110.102467. [PMID: 20392689] - Soumya J Koppikar, Amit S Choudhari, Snehal A Suryavanshi, Shweta Kumari, Samit Chattopadhyay, Ruchika Kaul-Ghanekar. Aqueous cinnamon extract (ACE-c) from the bark of Cinnamomum cassia causes apoptosis in human cervical cancer cell line (SiHa) through loss of mitochondrial membrane potential.
BMC cancer.
2010 May; 10(?):210. doi:
10.1186/1471-2407-10-210. [PMID: 20482751] - Soizic Guihard, Denis Clay, Laurence Cocault, Nathalie Saulnier, Paule Opolon, Michèle Souyri, Gilles Pagès, Jacques Pouysségur, Françoise Porteu, Murielle Gaudry. The MAPK ERK1 is a negative regulator of the adult steady-state splenic erythropoiesis.
Blood.
2010 May; 115(18):3686-94. doi:
10.1182/blood-2009-09-242487. [PMID: 20223923] - Sanghoon Kwon, Dongbum Kim, Jae Won Rhee, Jeong-A Park, Dae-Won Kim, Doo-Sik Kim, Younghee Lee, Hyung-Joo Kwon. ASB9 interacts with ubiquitous mitochondrial creatine kinase and inhibits mitochondrial function.
BMC biology.
2010 Mar; 8(?):23. doi:
10.1186/1741-7007-8-23. [PMID: 20302626] - Ryoichi Fujiwara, Nghia Nguyen, Shujuan Chen, Robert H Tukey. Developmental hyperbilirubinemia and CNS toxicity in mice humanized with the UDP glucuronosyltransferase 1 (UGT1) locus.
Proceedings of the National Academy of Sciences of the United States of America.
2010 Mar; 107(11):5024-9. doi:
10.1073/pnas.0913290107. [PMID: 20194756] - Andrea Stofkova, Blanka Zelezna, Marianna Romzova, Olga Ulicna, Alexander Kiss, Martina Skurlova, Jana Jurcovicova. Effect of feeding status on adjuvant arthritis severity, cachexia, and insulin sensitivity in male Lewis rats.
Mediators of inflammation.
2010; 2010(?):. doi:
10.1155/2010/398026. [PMID: 20953376] - Young Woo Kim, Sung Min Lee, Sang Mi Shin, Se Jin Hwang, Janie S Brooks, Hee Eun Kang, Myung Gull Lee, Sang Chan Kim, Sang Geon Kim. Efficacy of sauchinone as a novel AMPK-activating lignan for preventing iron-induced oxidative stress and liver injury.
Free radical biology & medicine.
2009 Oct; 47(7):1082-92. doi:
10.1016/j.freeradbiomed.2009.07.018. [PMID: 19616619] - Erika Lattová, Eilean J McKenzie, Marco L H Gruwel, Vic Spicer, Radoslav Goldman, Hélène Perreault. Mass spectrometric study of N-glycans from serum of woodchucks with liver cancer.
Rapid communications in mass spectrometry : RCM.
2009 Sep; 23(18):2983-95. doi:
10.1002/rcm.4202. [PMID: 19685473] - Shweta Sharma, Chandana Haldar. Comparative effect of melatonin and vitamin E on phenylhydrazine-induced toxicity in the spleen of Funambulus pennanti.
Environmental toxicology.
2009 Feb; 24(1):1-9. doi:
10.1002/tox.20383. [PMID: 18442075] - Carla Giannina Zilli, Diego Mario Santa-Cruz, Gustavo Gabriel Yannarelli, Guillermo Osvaldo Noriega, María Luján Tomaro, Karina Beatriz Balestrasse. Heme Oxygenase Contributes to Alleviate Salinity Damage in Glycine max L. Leaves.
International journal of cell biology.
2009; 2009(?):848516. doi:
10.1155/2009/848516. [PMID: 20130761] - Ann C Rice, Steven M Shapiro. A new animal model of hemolytic hyperbilirubinemia-induced bilirubin encephalopathy (kernicterus).
Pediatric research.
2008 Sep; 64(3):265-9. doi:
10.1203/pdr.0b013e31817d9be0. [PMID: 18458656] - Wenlei Jiang, Marco Constante, Manuela M Santos. Anemia upregulates lipocalin 2 in the liver and serum.
Blood cells, molecules & diseases.
2008 Sep; 41(2):169-74. doi:
10.1016/j.bcmd.2008.04.006. [PMID: 18519167] - Kettelin A Arbos, Ligia M Claro, Lucielly Borges, Cid A M Santos, Almeriane M Weffort-Santos. Human erythrocytes as a system for evaluating the antioxidant capacity of vegetable extracts.
Nutrition research (New York, N.Y.).
2008 Jul; 28(7):457-63. doi:
10.1016/j.nutres.2008.04.004. [PMID: 19083446] - Aboudoulatif Diallo, Messanvi Gbeassor, Ahoefa Vovor, Kwashie Eklu-Gadegbeku, Kodjo Aklikokou, Amegnona Agbonon, Ange A Abena, Comla de Souza, Koffi Akpagana. Effect of Tectona grandis on phenylhydrazine-induced anaemia in rats.
Fitoterapia.
2008 Jul; 79(5):332-6. doi:
10.1016/j.fitote.2008.02.005. [PMID: 18504074] - Kyong-Son Min, Naoyuki Iwata, Noriko Tetsutikawahara, Satomi Onosaka, Keiichi Tanaka. Effect of hemolytic and iron-deficiency anemia on intestinal absorption and tissue accumulation of cadmium.
Toxicology letters.
2008 Jun; 179(1):48-52. doi:
10.1016/j.toxlet.2008.04.001. [PMID: 18485624] - Naval Kapuriya, Kalpana Kapuriya, Xiuguo Zhang, Ting-Chao Chou, Rajesh Kakadiya, Yu-Tse Wu, Tung-Hu Tsai, Yu-Ting Chen, Te-Chang Lee, Anamik Shah, Yogesh Naliapara, Tsann-Long Su. Synthesis and biological activity of stable and potent antitumor agents, aniline nitrogen mustards linked to 9-anilinoacridines via a urea linkage.
Bioorganic & medicinal chemistry.
2008 May; 16(10):5413-23. doi:
10.1016/j.bmc.2008.04.024. [PMID: 18450456] - Erika Lattová, Sonal Varma, Tedros Bezabeh, Ladislav Petrus, Hélène Perreault. Mass spectrometric profiling of N-linked oligosaccharides and uncommon glycoform in mouse serum with head and neck tumor.
Journal of the American Society for Mass Spectrometry.
2008 May; 19(5):671-85. doi:
10.1016/j.jasms.2008.01.016. [PMID: 18353675] - Jan H Zivny, Monique P Gelderman, Fei Xu, John Piper, Karel Holada, Jan Simak, Jaroslav G Vostal. Reduced erythroid cell and erythropoietin production in response to acute anemia in prion protein-deficient (Prnp-/-) mice.
Blood cells, molecules & diseases.
2008 May; 40(3):302-7. doi:
10.1016/j.bcmd.2007.09.009. [PMID: 17964827] - Krishnan Venkataraman, Yong-Moon Lee, Jason Michaud, Shobha Thangada, Youxi Ai, Herbert L Bonkovsky, Nehal S Parikh, Cheryl Habrukowich, Timothy Hla. Vascular endothelium as a contributor of plasma sphingosine 1-phosphate.
Circulation research.
2008 Mar; 102(6):669-76. doi:
10.1161/circresaha.107.165845. [PMID: 18258856] - Gerardo Barragán Mejia, Cecilia Ridaura Sanz, Marco Martínez Avila, Armando Valenzuela Peraza, David Calderón Guzmán, Hugo Juárez Olguín, Aline Morales Ramírez, Edna García Cruz. Experimental hemolysis model to study bilirubin encephalopathy in rat brain.
Journal of neuroscience methods.
2008 Feb; 168(1):35-41. doi:
10.1016/j.jneumeth.2007.09.003. [PMID: 17949822] - Solomon Umukoro, Babatunde Rasaq Ashorobi. Further pharmacological studies on aqueous seed extract of Aframomum melegueta in rats.
Journal of ethnopharmacology.
2008 Feb; 115(3):489-93. doi:
10.1016/j.jep.2007.10.019. [PMID: 18060710] - Prajakta S Palkar, Binu K Philip, Ramesh N Reddy, Harihara M Mehendale. Priming dose of phenylhydrazine protects against hemolytic and lethal effects of 2-butoxyethanol.
Toxicology and applied pharmacology.
2007 Nov; 225(1):102-12. doi:
10.1016/j.taap.2007.06.011. [PMID: 17850838] - Monica Guarini, Angela Stabile, Gabriella Cavallini, Alessio Donati, Ettore Bergamini. Effects of oxidative stress on the Dolichol content of isolated rat liver cells.
Free radical research.
2007 Nov; 41(11):1283-8. doi:
10.1080/10715760701689568. [PMID: 17957544] - Sugima Rappert, Renjie Li, Mariya Kokova, Mathias Antholz, Stephanie Nagorny, Wittko Francke, Rudolf Müller. Degradation of 2,5-dimethylpyrazine by Rhodococcus erythropolis strain DP-45 isolated from a waste gas treatment plant of a fishmeal processing company.
Biodegradation.
2007 Oct; 18(5):585-96. doi:
10.1007/s10532-006-9091-5. [PMID: 17120096] - María José Raso, Alfonso Muñoz, Manuel Pineda, Pedro Piedras. Biochemical characterisation of an allantoate-degrading enzyme from French bean (Phaseolus vulgaris): the requirement of phenylhydrazine.
Planta.
2007 Oct; 226(5):1333-42. doi:
10.1007/s00425-007-0570-7. [PMID: 17594111] - Virgilio L Lew, Nuala Daw, Zipora Etzion, Teresa Tiffert, Adaeze Muoma, Laura Vanagas, Robert M Bookchin. Effects of age-dependent membrane transport changes on the homeostasis of senescent human red blood cells.
Blood.
2007 Aug; 110(4):1334-42. doi:
10.1182/blood-2006-11-057232. [PMID: 17456724] - Jia-Ming Liu, Xiao-Jie Cui, Lai-Ming Li, Geng-Min Fu, Shao-Xian Lin, Min-Lan Yang, Mei-Ying Xu, Zhi-Qun Wu. Determination of trace selenium by solid substrate-room temperature phosphorescence enhancing method based on potassium chlorate oxidizing phenyl hydrazine-1,2-dihydroxynaphthalene-3,6-disulfonic acid system.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2007 Apr; 66(4-5):1194-8. doi:
10.1016/j.saa.2006.06.007. [PMID: 16959532] - Upa Kukongviriyapan, Saowanee Luangaram, Krissadarut Leekhaosoong, Veerapol Kukongviriyapan, Srisomporn Preeprame. Antioxidant and vascular protective activities of Cratoxylum formosum, Syzygium gratum and Limnophila aromatica.
Biological & pharmaceutical bulletin.
2007 Apr; 30(4):661-6. doi:
10.1248/bpb.30.661. [PMID: 17409498] - Saowanee Luangaram, Upa Kukongviriyapan, Poungrat Pakdeechote, Veerapol Kukongviriyapan, Patchareewan Pannangpetch. Protective effects of quercetin against phenylhydrazine-induced vascular dysfunction and oxidative stress in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2007 Mar; 45(3):448-55. doi:
10.1016/j.fct.2006.09.008. [PMID: 17084956] - Erika Lattová, Vincent C Chen, Sonal Varma, Tedros Bezabeh, Hélène Perreault. Matrix-assisted laser desorption/ionization on-target method for the investigation of oligosaccharides and glycosylation sites in glycopeptides and glycoproteins.
Rapid communications in mass spectrometry : RCM.
2007; 21(10):1644-50. doi:
10.1002/rcm.3007. [PMID: 17465012] - Sarah H Atkinson, Kirk Rockett, Giorgio Sirugo, Philip A Bejon, Anthony Fulford, Maria A O'Connell, Robin Bailey, Dominic P Kwiatkowski, Andrew M Prentice. Seasonal childhood anaemia in West Africa is associated with the haptoglobin 2-2 genotype.
PLoS medicine.
2006 May; 3(5):e172. doi:
10.1371/journal.pmed.0030172. [PMID: 16637741] - Erika Lattová, Petra Kapková, Oleg Krokhin, Hélène Perreault. Method for investigation of oligosaccharides from glycopeptides: direct determination of glycosylation sites in proteins.
Analytical chemistry.
2006 May; 78(9):2977-84. doi:
10.1021/ac0519918. [PMID: 16642983] - Thomas F Kalhorn, William N Howald, Scott Cole, Brian Phillips, Joanne Wang, John T Slattery, Jeannine S McCune. Rapid quantitation of cyclophosphamide metabolites in plasma by liquid chromatography-mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2006 May; 835(1-2):105-13. doi:
10.1016/j.jchromb.2006.03.022. [PMID: 16581318] - Kazutoshi Ono, Kazuki Yanagida, Tadao Oikawa, Tadashi Ogawa, Kenji Soda. Alanine racemase of alfalfa seedlings (Medicago sativa L.): first evidence for the presence of an amino acid racemase in plants.
Phytochemistry.
2006 May; 67(9):856-60. doi:
10.1016/j.phytochem.2006.02.017. [PMID: 16616264] - Kavithalakshmi S Natarajan, Madhusudhanan Narasimhan, K Radha Shanmugasundaram, E R B Shanmugasundaram. Antioxidant activity of a salt-spice-herbal mixture against free radical induction.
Journal of ethnopharmacology.
2006 Apr; 105(1-2):76-83. doi:
10.1016/j.jep.2005.09.043. [PMID: 16337350]
