o-cresol (BioDeep_00000405504)

Main id: BioDeep_00000004708

 

natural product


代谢物信息卡片


o-cresol

化学式: C7H8O (108.0575)
中文名称: 邻甲酚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=CC=CC=C1O
InChI: InChI=1S/C7H8O/c1-6-4-2-3-5-7(6)8/h2-5,8H,1H3

描述信息

A cresol that is phenol substituted by a methyl group at position 2. It is a minor urinary metabolite of toluene.

同义名列表

3 个代谢物同义名

o-cresol; o-Cresol; o-Cresol



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

89 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 13 ALB, CAT, CYP1A1, CYP2B6, CYP2C8, CYP2E1, GSTM1, HPGDS, NAT2, PPARG, PTGS2, TYR, XDH
Peripheral membrane protein 6 ACHE, CYP1A1, CYP1B1, CYP2B6, CYP2E1, PTGS2
Endoplasmic reticulum membrane 7 CYP1A1, CYP1A2, CYP1B1, CYP2B6, CYP2C8, CYP2E1, PTGS2
Nucleus 4 ACHE, ALB, NAT2, PPARG
cytosol 7 ALB, CAT, GSTM1, HPGDS, NAT2, PPARG, XDH
centrosome 1 ALB
nucleoplasm 3 ATP2B1, HPGDS, PPARG
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 3 ACHE, ATP2B1, NAT2
Multi-pass membrane protein 3 ATP2B1, NAT2, SLC45A2
Synapse 2 ACHE, ATP2B1
cell surface 1 ACHE
glutamatergic synapse 1 ATP2B1
Golgi apparatus 3 ACHE, ALB, ATRN
mitochondrial inner membrane 2 CYP1A1, CYP2E1
neuromuscular junction 1 ACHE
neuronal cell body 1 NAT2
presynaptic membrane 1 ATP2B1
Lysosome 1 TYR
plasma membrane 5 ACHE, ATP2B1, ATRN, CYP2C8, NAT2
synaptic vesicle membrane 1 ATP2B1
Membrane 6 ACHE, ATP2B1, CAT, CYP1B1, NAT2, SLC45A2
axon 1 NAT2
basolateral plasma membrane 2 ATP2B1, NAT2
caveola 1 PTGS2
extracellular exosome 6 ALB, ALDH2, ATP2B1, ATRN, CAT, NAT2
endoplasmic reticulum 2 ALB, PTGS2
extracellular space 4 ACHE, ALB, ATRN, XDH
perinuclear region of cytoplasm 3 ACHE, PPARG, TYR
mitochondrion 4 ALDH2, CAT, CYP1A1, CYP1B1
protein-containing complex 3 ALB, CAT, PTGS2
intracellular membrane-bounded organelle 11 ATP2B1, CAT, CYP1A1, CYP1A2, CYP1B1, CYP2B6, CYP2C8, CYP2E1, HPGDS, PPARG, TYR
Microsome membrane 6 CYP1A1, CYP1A2, CYP1B1, CYP2B6, CYP2E1, PTGS2
Single-pass type I membrane protein 2 ATRN, TYR
Secreted 2 ACHE, ALB
extracellular region 3 ACHE, ALB, CAT
[Isoform 2]: Secreted 1 ATRN
Mitochondrion matrix 1 ALDH2
mitochondrial matrix 2 ALDH2, CAT
Extracellular side 1 ACHE
anchoring junction 1 ALB
transcription regulator complex 1 NAT2
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
Melanosome membrane 2 SLC45A2, TYR
Golgi-associated vesicle 1 TYR
Mitochondrion inner membrane 2 CYP1A1, CYP2E1
focal adhesion 1 CAT
Peroxisome 2 CAT, XDH
basement membrane 1 ACHE
sarcoplasmic reticulum 1 XDH
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
lateral plasma membrane 1 ATP2B1
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
receptor complex 1 PPARG
neuron projection 1 PTGS2
ciliary basal body 1 ALB
chromatin 1 PPARG
cell projection 1 ATP2B1
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
Basolateral cell membrane 1 ATP2B1
Lipid-anchor, GPI-anchor 1 ACHE
[Isoform 3]: Secreted 1 ATRN
intercellular bridge 1 GSTM1
Melanosome 1 TYR
Presynaptic cell membrane 1 ATP2B1
side of membrane 1 ACHE
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 2 ALB, PTGS2
platelet alpha granule lumen 1 ALB
immunological synapse 1 ATP2B1
synaptic cleft 1 ACHE
external side of apical plasma membrane 1 NAT2
[Isoform 1]: Cell membrane 1 ATRN
catalase complex 1 CAT
photoreceptor ribbon synapse 1 ATP2B1
[Isoform H]: Cell membrane 1 ACHE
NatA complex 1 NAT2
ciliary transition fiber 1 ALB


文献列表

  • Pengfei Feng, Yunshuang Li, Kangshuai Li, Weiyan Duan, Ran Guo. Effects of o-cresol on the growth and biochemical compositions in marine microalgae. Marine environmental research. 2023 Sep; 191(?):106164. doi: 10.1016/j.marenvres.2023.106164. [PMID: 37713779]
  • Falko Frenzel, Thorsten Buhrke, Irina Wenzel, Jennifer Andrack, Jan Hielscher, Alfonso Lampen. Use of in silico models for prioritization of heat-induced food contaminants in mutagenicity and carcinogenicity testing. Archives of toxicology. 2017 Sep; 91(9):3157-3174. doi: 10.1007/s00204-016-1924-3. [PMID: 28091709]
  • Muhammad Imran, Hafiz Faisal Usman, Humera Shafi, Muhammad Sarwar, Muhammad Ashraf Tahir. Development of Rapid and Economical Colorimetric Screening Method for p-Phenylenediamine in Variety of Biological Matrices and its Application to Eleven Fatal Cases of p-Phenylenediamine Poisoning. Journal of forensic sciences. 2017 Mar; 62(2):483-487. doi: 10.1111/1556-4029.13297. [PMID: 27957731]
  • Alberto Thalison Silveira, Ana Carolina Campos Albuquerque, José Salvador Lepera, Isarita Martins. Diazepam influences urinary bioindicator of occupational toluene exposure. Environmental toxicology and pharmacology. 2016 Dec; 48(?):191-196. doi: 10.1016/j.etap.2016.10.012. [PMID: 27816004]
  • Axelle Marchand, Rocio Aranda-Rodriguez, Robert Tardif, Andy Nong, Sami Haddad. Evaluation and modeling of the impact of coexposures to VOC mixtures on urinary biomarkers. Inhalation toxicology. 2016; 28(6):260-73. doi: 10.3109/08958378.2016.1162232. [PMID: 27053005]
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  • Mariya S Liyasova, Lawrence M Schopfer, Oksana Lockridge. Cresyl saligenin phosphate makes multiple adducts on free histidine, but does not form an adduct on histidine 438 of human butyrylcholinesterase. Chemico-biological interactions. 2013 Mar; 203(1):103-7. doi: 10.1016/j.cbi.2012.07.006. [PMID: 22898212]
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