Galangin (BioDeep_00000269978)

 

Secondary id: BioDeep_00000002806

natural product PANOMIX_OTCML-2023


代谢物信息卡片


4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-phenyl- (9CI)

化学式: C15H10O5 (270.0528)
中文名称: 高良姜素
谱图信息: 最多检出来源 Viridiplantae(plant) 42.83%

分子结构信息

SMILES: c1(cc(c2c(c1)oc(c(c2=O)O)c1ccccc1)O)O
InChI: InChI=1S/C15H10O5/c16-9-6-10(17)12-11(7-9)20-15(14(19)13(12)18)8-4-2-1-3-5-8/h1-7,16-17,19H

描述信息

D009676 - Noxae > D009153 - Mutagens
Galangin (Norizalpinin) is?an?agonist/antagonist?of the?arylhydrocarbon?receptor. Galangin (Norizalpinin) also shows inhibition of CYP1A1 activity.
Galangin (Norizalpinin) is?an?agonist/antagonist?of the?arylhydrocarbon?receptor. Galangin (Norizalpinin) also shows inhibition of CYP1A1 activity.

同义名列表

31 个代谢物同义名

4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-phenyl- (9CI); 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-phenyl-; 4H-Benzopyran-4-one, 3,5,7-trihydroxy-2-phenyl-; 5-18-04-00567 (Beilstein Handbook Reference); 3,5,7-trihydroxy-2-phenyl-chromen-4-one; 3,5,7-Trihydroxy-2-phenyl-4-benzopyrone; 3,5,7-trihydroxy-2-phenyl-4-chromenone; 3,5,7-trihydroxy-2-phenylchromen-4-one; 3,5,7-trihydroxy-2-phenyl-chromone; FLAVONE, 3,5,7-TRIHYDROXY-; 3,5,7-Trihydroxyflavone; EINECS 208-960-4; NCGC00142457-01; NCGC00017220-01; 282200_ALDRICH; MEGxp0_000533; ACon1_000977; ZINC00120273; Norizalpinin; BRN 0272179; AIDS-003058; AIDS003058; NSC 407229; NSC407229; 548-83-4; ST056288; TNP00099; Galangin; C10044; 3,5,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one; Galangin



数据库引用编号

47 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

223 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 AHR, BCL2, CASP3, CAT, CYP1A1, MAPK14, MAPK8, PTGS2, RELA, TP53, VEGFA
Peripheral membrane protein 4 ACHE, CYP1A1, CYP1B1, PTGS2
Endoplasmic reticulum membrane 5 BCL2, CYP1A1, CYP1B1, HMOX1, PTGS2
Nucleus 10 ACHE, AHR, BCL2, CASP3, HMOX1, MAPK14, MAPK8, RELA, TP53, VEGFA
cytosol 9 AHR, BCL2, CASP3, CAT, HMOX1, MAPK14, MAPK8, RELA, TP53
centrosome 1 TP53
nucleoplasm 7 AHR, CASP3, HMOX1, MAPK14, MAPK8, RELA, TP53
Cell membrane 2 ACHE, TNF
Cytoplasmic side 1 HMOX1
Synapse 2 ACHE, MAPK8
cell surface 3 ACHE, TNF, VEGFA
glutamatergic synapse 3 CASP3, MAPK14, RELA
Golgi apparatus 2 ACHE, VEGFA
Golgi membrane 1 INS
mitochondrial inner membrane 1 CYP1A1
neuromuscular junction 1 ACHE
neuronal cell body 2 CASP3, TNF
plasma membrane 3 ACHE, IGHE, TNF
Membrane 7 ACHE, BCL2, CAT, CYP1B1, HMOX1, TP53, VEGFA
axon 2 CCK, MAPK8
caveola 1 PTGS2
extracellular exosome 1 CAT
endoplasmic reticulum 5 BCL2, HMOX1, PTGS2, TP53, VEGFA
extracellular space 9 ACHE, CCK, HMOX1, IGHE, IL10, IL6, INS, TNF, VEGFA
perinuclear region of cytoplasm 2 ACHE, HMOX1
adherens junction 1 VEGFA
mitochondrion 6 BCL2, CAT, CYP1A1, CYP1B1, MAPK14, TP53
protein-containing complex 5 AHR, BCL2, CAT, PTGS2, TP53
intracellular membrane-bounded organelle 3 CAT, CYP1A1, CYP1B1
Microsome membrane 3 CYP1A1, CYP1B1, PTGS2
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 IGHE
Secreted 6 ACHE, CCK, IL10, IL6, INS, VEGFA
extracellular region 10 ACHE, CAT, CCK, IGHE, IL10, IL6, INS, MAPK14, TNF, VEGFA
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, HMOX1
Mitochondrion matrix 1 TP53
mitochondrial matrix 2 CAT, TP53
Extracellular side 1 ACHE
transcription regulator complex 3 AHR, RELA, TP53
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 TNF
Secreted, extracellular space, extracellular matrix 1 VEGFA
nucleolus 1 TP53
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Mitochondrion inner membrane 1 CYP1A1
Membrane raft 1 TNF
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 TP53
focal adhesion 1 CAT
extracellular matrix 1 VEGFA
Peroxisome 1 CAT
basement membrane 1 ACHE
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Nucleus, PML body 1 TP53
PML body 1 TP53
secretory granule 1 VEGFA
nuclear speck 1 MAPK14
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 1 PTGS2
chromatin 3 AHR, RELA, TP53
IgE immunoglobulin complex 1 IGHE
phagocytic cup 1 TNF
spindle pole 1 MAPK14
Lipid-anchor, GPI-anchor 1 ACHE
[Isoform 2]: Cell membrane 1 IGHE
site of double-strand break 1 TP53
endosome lumen 1 INS
aryl hydrocarbon receptor complex 1 AHR
side of membrane 1 ACHE
germ cell nucleus 1 TP53
replication fork 1 TP53
myelin sheath 1 BCL2
ficolin-1-rich granule lumen 2 CAT, MAPK14
secretory granule lumen 3 CAT, INS, MAPK14
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 IL6, INS, PTGS2
nuclear matrix 1 TP53
transcription repressor complex 1 TP53
platelet alpha granule lumen 1 VEGFA
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
Single-pass type IV membrane protein 1 HMOX1
[Isoform 1]: Nucleus 1 TP53
synaptic cleft 1 ACHE
basal dendrite 1 MAPK8
death-inducing signaling complex 1 CASP3
[Isoform 3]: Cell membrane 1 IGHE
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
BAD-BCL-2 complex 1 BCL2
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
NF-kappaB p50/p65 complex 1 RELA
[Isoform H]: Cell membrane 1 ACHE
NF-kappaB complex 1 RELA
nuclear aryl hydrocarbon receptor complex 1 AHR
cytosolic aryl hydrocarbon receptor complex 1 AHR
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Qinghua Lan, Shuanghu Wang, Zhouming Chen, Junyan Hua, Jieru Hu, Songmei Luo, Yanyan Xu. Near-infrared-responsive GE11-CuS@Gal nanoparticles as an intelligent drug release system for targeting therapy against oral squamous cell carcinoma. International journal of pharmaceutics. 2024 Jan; 649(?):123667. doi: 10.1016/j.ijpharm.2023.123667. [PMID: 38048890]
  • Daibo Wang, Junren Chen, Lin Pu, Lei Yu, Fang Xiong, Luyao Sun, Qian Yu, Xiaoyu Cao, Yan Chen, Fu Peng, Cheng Peng. Galangin: A food-derived flavonoid with therapeutic potential against a wide spectrum of diseases. Phytotherapy research : PTR. 2023 Sep; ?(?):. doi: 10.1002/ptr.8013. [PMID: 37748788]
  • Tao Yang, Haiqiong Liu, Chaobo Yang, Huaqiang Mo, Xianbao Wang, Xudong Song, Luping Jiang, Ping Deng, Ran Chen, Pengcui Wu, Aihua Chen, Jing Yan. Galangin Attenuates Myocardial Ischemic Reperfusion-Induced Ferroptosis by Targeting Nrf2/Gpx4 Signaling Pathway. Drug design, development and therapy. 2023; 17(?):2495-2511. doi: 10.2147/dddt.s409232. [PMID: 37637264]
  • Xiaoting Wang, Xinglei Xiao. Galangin inhibits lipopolysaccharide-induced inflammation and stimulates osteogenic differentiation of bone marrow mesenchymal stem cells via regulation of AKT/mTOR signaling. Allergologia et immunopathologia. 2023; 51(1):133-139. doi: 10.15586/aei.v51i1.741. [PMID: 36617832]
  • Bing Wu, Changwu Xu, Hua-Sheng Ding, Liqiang Qiu, Ji-Xian Gao, Ming Li, Yuanguo Xiong, Hao Xia, Xiaoxiong Liu. Galangin inhibits neointima formation induced by vascular injury via regulating the PI3K/AKT/mTOR pathway. Food & function. 2022 Nov; 13(23):12077-12092. doi: 10.1039/d2fo02441a. [PMID: 36367287]
  • Ke Chen, Ran Xue, Yaping Geng, Shenshen Zhang. Galangin inhibited ferroptosis through activation of the PI3K/AKT pathway in vitro and in vivo. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2022 11; 36(11):e22569. doi: 10.1096/fj.202200935r. [PMID: 36183339]
  • Nisita Chaihongsa, Putcharawipa Maneesai, Weerapon Sangartit, Siwayu Rattanakanokchai, Prapassorn Potue, Juthamas Khamseekaew, Sarawoot Bunbupha, Poungrat Pakdeechote. Cardiorenal dysfunction and hypertrophy induced by renal artery occlusion are normalized by galangin treatment in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 Aug; 152(?):113231. doi: 10.1016/j.biopha.2022.113231. [PMID: 35687907]
  • Samir A Salama, Gamil M Abd-Allah, Hesham S Gad, Ahmed M Kabel. Galangin attenuates cadmium-evoked nephrotoxicity: Targeting nucleotide-binding domain-like receptor pyrin domain containing 3 inflammasome, nuclear factor erythroid 2-related factor 2, and nuclear factor kappa B signaling. Journal of biochemical and molecular toxicology. 2022 Jul; 36(7):e23059. doi: 10.1002/jbt.23059. [PMID: 35384154]
  • Thamizharasi Erusappan, Sivasakthi Paramasivam, Sanmuga Priya Ekambaram. Identification of galangin as the bioactive compound from Alpinia calcarata (Haw.) Roscoe rhizomes to inhibit IRAK-1/ MAPK/ NF-κB p65 and JAK-1 signaling in LPS stimulated RAW 264.7 cells. Journal of ethnopharmacology. 2022 Apr; 288(?):114975. doi: 10.1016/j.jep.2022.114975. [PMID: 35026343]
  • Anand Kumar Sahu, Ashok Kumar Mishra. Photophysical Behavior of Plant Flavonols Galangin, Kaempferol, Quercetin, and Myricetin in Homogeneous Media and the DMPC Model Membrane: Unveiling the Influence of the B-Ring Hydroxylation of Flavonols. The journal of physical chemistry. B. 2022 04; 126(15):2863-2875. doi: 10.1021/acs.jpcb.2c00929. [PMID: 35404618]
  • Xiongwei Deng, Hailang Le, Taohong Wan, Meizhi Weng, Yongzhen Tan. Galangin alleviates rheumatoid arthritis in rats by downregulating the phosphatidylinositol 3-kinase/protein kinase B signaling pathway. Bioengineered. 2022 04; 13(4):11192-11201. doi: 10.1080/21655979.2022.2062969. [PMID: 35485325]
  • Xichuan Li, Ce Wang, Jinqian Chen, Xia Hu, Hao Zhang, Zhiying Li, Bei Lan, Wei Zhang, Yanjun Su, Chunze Zhang. Potential interactions among myricetin and dietary flavonols through the inhibition of human UDP-glucuronosyltransferase in vitro. Toxicology letters. 2022 Apr; 358(?):40-47. doi: 10.1016/j.toxlet.2022.01.007. [PMID: 35063619]
  • Manal A Alfwuaires. Galangin mitigates oxidative stress, inflammation, and apoptosis in a rat model of methotrexate hepatotoxicity. Environmental science and pollution research international. 2022 Mar; 29(14):20279-20288. doi: 10.1007/s11356-021-16804-z. [PMID: 34729716]
  • Hany H Arab, Ahmed M Ashour, Ahmed H Eid, El-Shaimaa A Arafa, Hana J Al Khabbaz, Sarah A Abd El-Aal. Targeting oxidative stress, apoptosis, and autophagy by galangin mitigates cadmium-induced renal damage: Role of SIRT1/Nrf2 and AMPK/mTOR pathways. Life sciences. 2022 Feb; 291(?):120300. doi: 10.1016/j.lfs.2021.120300. [PMID: 34999115]
  • Yingli Jin, Panpan Yang, Li Wang, Zeyuan Gao, Jia Lv, Zheyu Cui, Tiedong Wang, Dacheng Wang, Lin Wang. Galangin as a direct inhibitor of vWbp protects mice from Staphylococcus aureus-induced pneumonia. Journal of cellular and molecular medicine. 2022 02; 26(3):828-839. doi: 10.1111/jcmm.17129. [PMID: 34931454]
  • Ke Hu, Yuxian Li, Ling Jin, Yuefu Chen, Lijun Chen, Yingjun Zhang, Minjiang Huang, Yan Ding, Huiming Yin, Minghua Liang, Bifeng Tan. Protective Effect of Galangin Methylation Modification Based on Cell Imaging on Inflammatory Lung Injury and Its Molecular Mechanism. Contrast media & molecular imaging. 2022; 2022(?):7511345. doi: 10.1155/2022/7511345. [PMID: 36072628]
  • Francesco Caruso, Molly Berinato, Melissa Hernandez, Stuart Belli, Christopher Smart, Miriam Rossi. Antioxidant properties of bee propolis and an important component, galangin, described by X-ray crystal structure, DFT-D and hydrodynamic voltammetry. PloS one. 2022; 17(5):e0267624. doi: 10.1371/journal.pone.0267624. [PMID: 35584109]
  • Hamed Hajipour, Mohammad Nouri, Marjan Ghorbani, Ali Bahramifar, Reza Zolfaghari Emameh, Ramezan Ali Taheri. Targeted nanostructured lipid carrier containing galangin as a promising adjuvant for improving cytotoxic effects of chemotherapeutic agents. Naunyn-Schmiedeberg's archives of pharmacology. 2021 12; 394(12):2353-2362. doi: 10.1007/s00210-021-02152-9. [PMID: 34522984]
  • Hyun-Kyung Song, Sun Haeng Park, Hye Jin Kim, Seol Jang, Taesoo Kim. Alpinia officinarum water extract inhibits the atopic dermatitis-like responses in NC/Nga mice by regulation of inflammatory chemokine production. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Dec; 144(?):112322. doi: 10.1016/j.biopha.2021.112322. [PMID: 34656059]
  • Yao-Dong Song, Yan-Yan Liu, De-Jian Li, Shu-Jun Yang, Qiao-Fang Wang, Yan-Na Liu, Meng-Ke Li, Chao-Peng Mei, Hu-Ning Cui, San-Yang Chen, Chang-Ju Zhu. Galangin ameliorates severe acute pancreatitis in mice by activating the nuclear factor E2-related factor 2/heme oxygenase 1 pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Dec; 144(?):112293. doi: 10.1016/j.biopha.2021.112293. [PMID: 34634559]
  • Nisita Chaihongsa, Putcharawipa Maneesai, Weerapon Sangartit, Prapassorn Potue, Sarawoot Bunbupha, Poungrat Pakdeechote. Galangin alleviates vascular dysfunction and remodelling through modulation of the TNF-R1, p-NF-κB and VCAM-1 pathways in hypertensive rats. Life sciences. 2021 Nov; 285(?):119965. doi: 10.1016/j.lfs.2021.119965. [PMID: 34543638]
  • A Madeswaran, S Brahmasundari, P G Midhuna. In silico molecular docking studies of certain commercially available flavonoids as effective antiviral agents against spike glycoprotein of SARS-CoV-2. European review for medical and pharmacological sciences. 2021 Nov; 25(21):6741-6744. doi: 10.26355/eurrev_202111_27119. [PMID: 34787879]
  • Samir A Salama, Mostafa M Elshafey. Galangin mitigates iron overload-triggered liver injury: Up-regulation of PPARγ and Nrf2 signaling, and abrogation of the inflammatory responses. Life sciences. 2021 Oct; 283(?):119856. doi: 10.1016/j.lfs.2021.119856. [PMID: 34329667]
  • Rajashri R Naik, Ashok K Shakya, Ghaleb A Oriquat, Shankar Katekhaye, Anant Paradkar, Hugo Fearnley, James Fearnley. Fatty Acid Analysis, Chemical Constituents, Biological Activity and Pesticide Residues Screening in Jordanian Propolis. Molecules (Basel, Switzerland). 2021 Aug; 26(16):. doi: 10.3390/molecules26165076. [PMID: 34443664]
  • Halil Ibrahim Guler, Gizem Tatar, Oktay Yildiz, Ali Osman Belduz, Sevgi Kolayli. Investigation of potential inhibitor properties of ethanolic propolis extracts against ACE-II receptors for COVID-19 treatment by molecular docking study. Archives of microbiology. 2021 Aug; 203(6):3557-3564. doi: 10.1007/s00203-021-02351-1. [PMID: 33950349]
  • Xiao-Hui Liang, Ming-Zhu Yu, Hai-Lian Shi, Xiao-Jun Wu. [Galangin enhances autophagy by inhibiting NF-κB pathway in gastric cancer MGC-803 cells]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2021 Aug; 46(16):4167-4174. doi: 10.19540/j.cnki.cjcmm.20210406.401. [PMID: 34467729]
  • Rajendra Sangaraju, Sateesh Alavala, Nasiruddin Nalban, Mahesh Kumar Jerald, Ramakrishna Sistla. Galangin ameliorates Imiquimod-Induced psoriasis-like skin inflammation in BALB/c mice via down regulating NF-κB and activation of Nrf2 signaling pathways. International immunopharmacology. 2021 Jul; 96(?):107754. doi: 10.1016/j.intimp.2021.107754. [PMID: 34162135]
  • Mohammad H Abukhalil, Osama Y Althunibat, Saleem H Aladaileh, Wesam Al-Amarat, Heba M Obeidat, Alayn' Al-Marddyah A Al-Khawalde, Omnia E Hussein, Manal A Alfwuaires, Abdulmohsen I Algefare, Khalid M Alanazi, Farhan K Al-Swailmi, Hany H Arab, Ayman M Mahmoud. Galangin attenuates diabetic cardiomyopathy through modulating oxidative stress, inflammation and apoptosis in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Jun; 138(?):111410. doi: 10.1016/j.biopha.2021.111410. [PMID: 33752930]
  • Xiucheng Li, Jiawei Jiang, Zhifan Yang, Songtao Jin, Xuanyuan Lu, Yu Qian. Galangin suppresses RANKL-induced osteoclastogenesis via inhibiting MAPK and NF-κB signalling pathways. Journal of cellular and molecular medicine. 2021 06; 25(11):4988-5000. doi: 10.1111/jcmm.16430. [PMID: 33939240]
  • Ankur Kumar Tanwar, Neha Dhiman, Amit Kumar, Vikas Jaitak. Engagement of phytoestrogens in breast cancer suppression: Structural classification and mechanistic approach. European journal of medicinal chemistry. 2021 Mar; 213(?):113037. doi: 10.1016/j.ejmech.2020.113037. [PMID: 33257172]
  • S H Aladaileh, F K Al-Swailmi, M H Abukhalil, M H Shalayel. Galangin protects against oxidative damage and attenuates inflammation and apoptosis via modulation of NF-κB p65 and caspase-3 signaling molecules in a rat model of diabetic nephropathy. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 2021 Feb; 72(1):. doi: 10.26402/jpp.2021.1.04. [PMID: 34099583]
  • Thamizharasi Erusappan, Sree Karani Kondapuram, Sanmuga Priya Ekambaram, Mohane Selvaraj Coumar. Investigation of Alpinia calcarata constituent interactions with molecular targets of rheumatoid arthritis: docking, molecular dynamics, and network approach. Journal of molecular modeling. 2021 Jan; 27(1):14. doi: 10.1007/s00894-020-04651-7. [PMID: 33403456]
  • Jing Fan, Xin-Huai Zhao, Tie-Jing Li. Heat treatment of galangin and kaempferol inhibits their benefits to improve barrier function in rat intestinal epithelial cells. The Journal of nutritional biochemistry. 2021 01; 87(?):108517. doi: 10.1016/j.jnutbio.2020.108517. [PMID: 33011286]
  • Xue Guan, Zhonghua Li, Shu Zhu, Meijia Cheng, Yetao Ju, Lu Ren, Guanlin Yang, Dongyu Min. Galangin attenuated cerebral ischemia-reperfusion injury by inhibition of ferroptosis through activating the SLC7A11/GPX4 axis in gerbils. Life sciences. 2021 Jan; 264(?):118660. doi: 10.1016/j.lfs.2020.118660. [PMID: 33127512]
  • María Fernanda García-Bustos, Agustín Moya Álvarez, Cecilia Pérez Brandan, Cecilia Parodi, Andrea Mabel Sosa, Valeria Carolina Buttazzoni Zuñiga, Oscar Marcelo Pastrana, Paula Manghera, Pablo Alejandro Peñalva, Jorge Diego Marco, Paola Andrea Barroso. Development of a Fluorescent Assay to Search New Drugs Using Stable tdTomato-Leishmania, and the Selection of Galangin as a Candidate With Anti-Leishmanial Activity. Frontiers in cellular and infection microbiology. 2021; 11(?):666746. doi: 10.3389/fcimb.2021.666746. [PMID: 34150675]
  • Rongrong Ou, Lianzhu Lin, Mouming Zhao, Zhiqing Xie. Action mechanisms and interaction of two key xanthine oxidase inhibitors in galangal: Combination of in vitro and in silico molecular docking studies. International journal of biological macromolecules. 2020 Nov; 162(?):1526-1535. doi: 10.1016/j.ijbiomac.2020.07.297. [PMID: 32777423]
  • Amal A Aloud, Veeramani Chinnadurai, Govindasamy Chandramohan, Mohammed A Alsaif, Khalid S Al-Numair. Galangin controls streptozotocin-caused glucose homeostasis and reverses glycolytic and gluconeogenic enzyme changes in rats. Archives of physiology and biochemistry. 2020 May; 126(2):101-106. doi: 10.1080/13813455.2018.1498521. [PMID: 30269607]
  • Alvaro José Hernández Tasco, Román Yesid Ramírez Rueda, Carlos José Alvarez, Fabiana Terezinha Sartori, Ana Claudia B C Sacilotto, Izabel Yoko Ito, Walter Vichnewski, Marcos José Salvador. Antibacterial and antifungal properties of crude extracts and isolated compounds from Lychnophora markgravii. Natural product research. 2020 Mar; 34(6):863-867. doi: 10.1080/14786419.2018.1503263. [PMID: 30445853]
  • Hongzhuan Xuan, Aiqun Ou, Shengyu Hao, Jiajun Shi, Xiaolu Jin. Galangin Protects against Symptoms of Dextran Sodium Sulfate-induced Acute Colitis by Activating Autophagy and Modulating the Gut Microbiota. Nutrients. 2020 Jan; 12(2):. doi: 10.3390/nu12020347. [PMID: 32013062]
  • Xinxu Zhang, Yuanyuan Deng, Juan Xiang, Huixia Liu, Jiani Zhang, Jie Liao, Ke Chen, Bo Liu, Jun Liu, Ying Pu. Galangin Improved Non-Alcoholic Fatty Liver Disease in Mice by Promoting Autophagy. Drug design, development and therapy. 2020; 14(?):3393-3405. doi: 10.2147/dddt.s258187. [PMID: 32884242]
  • Swagat Sharma, Corey R Hopkins. Review of Transient Receptor Potential Canonical (TRPC5) Channel Modulators and Diseases. Journal of medicinal chemistry. 2019 09; 62(17):7589-7602. doi: 10.1021/acs.jmedchem.8b01954. [PMID: 30943030]
  • Viviane Nogueira de Zorzi, Fernanda Haupenthal, Alexandra Seide Cardoso, Gustavo Cassol, Valdir A Facundo, Laudir J Bálico, Daniella K S Lima, Adair Roberto Soares Santos, Ana Flavia Furian, Mauro Schneider Oliveira, Luiz Fernando Freire Royes, Michele Rechia Fighera. Galangin Prevents Increased Susceptibility to Pentylenetetrazol-Stimulated Seizures by Prostaglandin E2. Neuroscience. 2019 08; 413(?):154-168. doi: 10.1016/j.neuroscience.2019.06.002. [PMID: 31200106]
  • Saleem H Aladaileh, Mohammad H Abukhalil, Sultan A M Saghir, Hamza Hanieh, Manal A Alfwuaires, Amer A Almaiman, May Bin-Jumah, Ayman M Mahmoud. Galangin Activates Nrf2 Signaling and Attenuates Oxidative Damage, Inflammation, and Apoptosis in a Rat Model of Cyclophosphamide-Induced Hepatotoxicity. Biomolecules. 2019 08; 9(8):. doi: 10.3390/biom9080346. [PMID: 31387329]
  • Rajendra Sangaraju, Nasiruddin Nalban, Sateesh Alavala, Vinoth Rajendran, Mahesh Kumar Jerald, Ramakrishna Sistla. Protective effect of galangin against dextran sulfate sodium (DSS)-induced ulcerative colitis in Balb/c mice. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 2019 Aug; 68(8):691-704. doi: 10.1007/s00011-019-01252-w. [PMID: 31147743]
  • Allan Fouache, Nada Zabaiou, Cyrille De Joussineau, Laurent Morel, Sandrine Silvente-Poirot, Amira Namsi, Gérard Lizard, Marc Poirot, Makoto Makishima, Silvère Baron, Jean-Marc A Lobaccaro, Amalia Trousson. Flavonoids differentially modulate liver X receptors activity-Structure-function relationship analysis. The Journal of steroid biochemistry and molecular biology. 2019 06; 190(?):173-182. doi: 10.1016/j.jsbmb.2019.03.028. [PMID: 30959154]
  • M Abinaya, M Gayathri. Inhibition of biofilm formation, quorum sensing activity and molecular docking study of isolated 3, 5, 7-Trihydroxyflavone from Alstonia scholaris leaf against P.aeruginosa. Bioorganic chemistry. 2019 06; 87(?):291-301. doi: 10.1016/j.bioorg.2019.03.050. [PMID: 30913464]
  • Wan-Xin Zhang, In-Cheng Chao, De-Jun Hu, Farid Shakerian, Liya Ge, Xiao Liang, Ying Wang, Jing Zhao, Shao-Ping Li. Comparison of Antioxidant Activity and Main Active Compounds Among Different Parts of Alpinia officinarum Hance Using High-Performance Thin Layer Chromatography-Bioautography. Journal of AOAC International. 2019 May; 102(3):726-733. doi: 10.5740/jaoacint.18-0307. [PMID: 30388970]
  • Valeria Curti, Vincenzo Zaccaria, Arold Jorel Tsetegho Sokeng, Marco Dacrema, Irene Masiello, Anna Mascaro, Giuseppe D'Antona, Maria Daglia. Bioavailability and In Vivo Antioxidant Activity of a Standardized Polyphenol Mixture Extracted from Brown Propolis. International journal of molecular sciences. 2019 Mar; 20(5):. doi: 10.3390/ijms20051250. [PMID: 30871097]
  • Tianyu Zhang, Xiyu Mei, Hao Ouyang, Bin Lu, Zengyang Yu, Zhengtao Wang, Lili Ji. Natural flavonoid galangin alleviates microglia-trigged blood-retinal barrier dysfunction during the development of diabetic retinopathy. The Journal of nutritional biochemistry. 2019 03; 65(?):1-14. doi: 10.1016/j.jnutbio.2018.11.006. [PMID: 30597356]
  • Rahul Datta, Amandeep Kaur, Isha Saraf, Inder Pal Singh, Sanehdeep Kaur. Effect of crude extracts and purified compounds of Alpinia galanga on nutritional physiology of a polyphagous lepidopteran pest, Spodoptera litura (Fabricius). Ecotoxicology and environmental safety. 2019 Jan; 168(?):324-329. doi: 10.1016/j.ecoenv.2018.10.065. [PMID: 30390531]
  • Hao Lu, Hui Yao, Rong Zou, Xiwen Chen, Hanlin Xu. Galangin Suppresses Renal Inflammation via the Inhibition of NF-κB, PI3K/AKT and NLRP3 in Uric Acid Treated NRK-52E Tubular Epithelial Cells. BioMed research international. 2019; 2019(?):3018357. doi: 10.1155/2019/3018357. [PMID: 31240210]
  • Chien-Chung Yang, Chih-Chung Lin, Li-Der Hsiao, Chuen-Mao Yang. Galangin Inhibits Thrombin-Induced MMP-9 Expression in SK-N-SH Cells via Protein Kinase-Dependent NF-κB Phosphorylation. International journal of molecular sciences. 2018 Dec; 19(12):. doi: 10.3390/ijms19124084. [PMID: 30562971]
  • Amal A Aloud, Veeramani Chinnadurai, Chandramohan Govindasamy, Mohammed A Alsaif, Khalid S Al-Numair. Galangin, a dietary flavonoid, ameliorates hyperglycaemia and lipid abnormalities in rats with streptozotocin-induced hyperglycaemia. Pharmaceutical biology. 2018 Dec; 56(1):302-308. doi: 10.1080/13880209.2018.1474931. [PMID: 29952676]
  • Abdullah A Elgazar, Nabil M Selim, Nabil M Abdel-Hamid, Mohammed A El-Magd, Hala M El Hefnawy. Isolates from Alpinia officinarum Hance attenuate LPS-induced inflammation in HepG2: Evidence from in silico and in vitro studies. Phytotherapy research : PTR. 2018 Jul; 32(7):1273-1288. doi: 10.1002/ptr.6056. [PMID: 29468851]
  • Yun Zhu, Qiu Rao, Xinhua Zhang, Xiaojun Zhou. Galangin induced antitumor effects in human kidney tumor cells mediated via mitochondrial mediated apoptosis, inhibition of cell migration and invasion and targeting PI3K/ AKT/mTOR signalling pathway. Journal of B.U.ON. : official journal of the Balkan Union of Oncology. 2018 May; 23(3):795-799. doi: . [PMID: 30003754]
  • Piotr Kuś, Igor Jerković, Martina Jakovljević, Stela Jokić. Extraction of bioactive phenolics from black poplar (Populus nigra L.) buds by supercritical CO2 and its optimization by response surface methodology. Journal of pharmaceutical and biomedical analysis. 2018 Apr; 152(?):128-136. doi: 10.1016/j.jpba.2018.01.046. [PMID: 29414004]
  • Nenad L Vukovic, Ana D Obradovic, Milena D Vukic, Danijela Jovanovic, Predrag M Djurdjevic. Cytotoxic, proapoptotic and antioxidative potential of flavonoids isolated from propolis against colon (HCT-116) and breast (MDA-MB-231) cancer cell lines. Food research international (Ottawa, Ont.). 2018 04; 106(?):71-80. doi: 10.1016/j.foodres.2017.12.056. [PMID: 29579978]
  • Dinesh Devadoss, Manikandan Ramar, Arulvasu Chinnasamy. Galangin, a dietary flavonol inhibits tumor initiation during experimental pulmonary tumorigenesis by modulating xenobiotic enzymes and antioxidant status. Archives of pharmacal research. 2018 Mar; 41(3):265-275. doi: 10.1007/s12272-014-0330-8. [PMID: 24497035]
  • Anuradha S Upadhye, Anagha Rajopadhye, Lourelle Dias. Development and validation of HPTLC fingerprints of three species of Alpinia with biomarker Galangin. BMC complementary and alternative medicine. 2018 Jan; 18(1):16. doi: 10.1186/s12906-017-2033-4. [PMID: 29338724]
  • Yang Li, Liquan Tong, Jingyan Zhang, Yafeng Zhang, Feng Zhang. Galangin Alleviates Liver Ischemia-Reperfusion Injury in a Rat Model by Mediating the PI3K/AKT Pathway. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2018; 51(3):1354-1363. doi: 10.1159/000495553. [PMID: 30481779]
  • Liping Sun, Lei Liao, Bei Wang. Potential Antinociceptive Effects of Chinese Propolis and Identification on Its Active Compounds. Journal of immunology research. 2018; 2018(?):5429543. doi: 10.1155/2018/5429543. [PMID: 30356413]
  • Amal A Aloud, Chinnadurai Veeramani, Chandramohan Govindasamy, Mohammed A Alsaif, Ahmed S El Newehy, Khalid S Al-Numair. Galangin, a dietary flavonoid, improves antioxidant status and reduces hyperglycemia-mediated oxidative stress in streptozotocin-induced diabetic rats. Redox report : communications in free radical research. 2017 Nov; 22(6):290-300. doi: 10.1080/13510002.2016.1273437. [PMID: 28030991]
  • Nanaware Sadhana, Sathiyanarayanan Lohidasan, Kakasaheb Ramoo Mahadik. Marker-based standardization and investigation of nutraceutical potential of Indian propolis. Journal of integrative medicine. 2017 Nov; 15(6):483-494. doi: 10.1016/s2095-4964(17)60360-1. [PMID: 29103419]
  • Ameesha Tomar, Swati Vasisth, Sana Irfan Khan, Salma Malik, Tapas Chandra Nag, Dharamveer Singh Arya, Jagriti Bhatia. Galangin ameliorates cisplatin induced nephrotoxicity in vivo by modulation of oxidative stress, apoptosis and inflammation through interplay of MAPK signaling cascade. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2017 Oct; 34(?):154-161. doi: 10.1016/j.phymed.2017.05.007. [PMID: 28899498]
  • Yu-Ching Huang, Ming-Shiun Tsai, Pei-Chi Hsieh, Jheng-Hong Shih, Tsu-Shing Wang, Yi-Chun Wang, Ting-Hui Lin, Sue-Hong Wang. Galangin ameliorates cisplatin-induced nephrotoxicity by attenuating oxidative stress, inflammation and cell death in mice through inhibition of ERK and NF-kappaB signaling. Toxicology and applied pharmacology. 2017 08; 329(?):128-139. doi: 10.1016/j.taap.2017.05.034. [PMID: 28558962]
  • Jung-Jin Lee, Ji-Hye Lee, Nam-Hui Yim, Joo-Hui Han, Jin Yeul Ma. Application of galangin, an active component of Alpinia officinarum Hance (Zingiberaceae), for use in drug-eluting stents. Scientific reports. 2017 08; 7(1):8207. doi: 10.1038/s41598-017-08410-2. [PMID: 28811550]
  • Sandra Salazar-Aguilar, Lucero Del Mar Ruiz-Posadas, Jorge Cadena-Iñiguez, Marcos Soto-Hernández, Edelmiro Santiago-Osorio, Itzen Aguiñiga-Sánchez, Ana Rocío Rivera-Martínez, Juan Francisco Aguirre-Medina. Sechium edule (Jacq.) Swartz, a New Cultivar with Antiproliferative Potential in a Human Cervical Cancer HeLa Cell Line. Nutrients. 2017 Jul; 9(8):. doi: 10.3390/nu9080798. [PMID: 28757593]
  • Merve Bacanlı, A Ahmet Başaran, Nurşen Başaran. The antioxidant, cytotoxic, and antigenotoxic effects of galangin, puerarin, and ursolic acid in mammalian cells. Drug and chemical toxicology. 2017 Jul; 40(3):256-262. doi: 10.1080/01480545.2016.1209680. [PMID: 27461151]
  • Yelin Kang, Bong-Gyu Kim, Sunghoon Kim, Youngshim Lee, Youngdae Yoon. Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain. Bioorganic & medicinal chemistry letters. 2017 02; 27(3):420-426. doi: 10.1016/j.bmcl.2016.12.051. [PMID: 28049590]
  • Namrita Lall, Elizabeth Mogapi, Marco Nuno de Canha, Bridget Crampton, Mabatho Nqephe, Ahmed A Hussein, Vivek Kumar. Insights into tyrosinase inhibition by compounds isolated from Greyia radlkoferi Szyszyl using biological activity, molecular docking and gene expression analysis. Bioorganic & medicinal chemistry. 2016 11; 24(22):5953-5959. doi: 10.1016/j.bmc.2016.09.054. [PMID: 27720556]
  • Jingyi Cao, Hainan Wang, Feifei Chen, Jianzheng Fang, Aiming Xu, Wei Xi, Shengli Zhang, Gang Wu, Zengjun Wang. Galangin inhibits cell invasion by suppressing the epithelial-mesenchymal transition and inducing apoptosis in renal cell carcinoma. Molecular medicine reports. 2016 May; 13(5):4238-44. doi: 10.3892/mmr.2016.5042. [PMID: 27035542]
  • Varsha S Honmore, Amit D Kandhare, Parag P Kadam, Vijay M Khedkar, Dhiman Sarkar, Subhash L Bodhankar, Anand A Zanwar, Supada R Rojatkar, Arun D Natu. Isolates of Alpinia officinarum Hance as COX-2 inhibitors: Evidence from anti-inflammatory, antioxidant and molecular docking studies. International immunopharmacology. 2016 Apr; 33(?):8-17. doi: 10.1016/j.intimp.2016.01.024. [PMID: 26849772]
  • Jacqueline Naylor, Aisling Minard, Hannah J Gaunt, Mohamed S Amer, Lesley A Wilson, Marco Migliore, Sin Y Cheung, Hussein N Rubaiy, Nicola M Blythe, Katie E Musialowski, Melanie J Ludlow, William D Evans, Ben L Green, Hongjun Yang, Yun You, Jing Li, Colin W G Fishwick, Katsuhiko Muraki, David J Beech, Robin S Bon. Natural and synthetic flavonoid modulation of TRPC5 channels. British journal of pharmacology. 2016 Feb; 173(3):562-74. doi: 10.1111/bph.13387. [PMID: 26565375]
  • Min Ae Han, Dong Hee Lee, Seon Min Woo, Bo Ram Seo, Kyoung-Jin Min, Shin Kim, Jong-Wook Park, Sang Hyun Kim, Yung Hyun Choi, Taeg Kyu Kwon. Galangin sensitizes TRAIL-induced apoptosis through down-regulation of anti-apoptotic proteins in renal carcinoma Caki cells. Scientific reports. 2016 Jan; 6(?):18642. doi: 10.1038/srep18642. [PMID: 26725939]
  • Qiong-Yu Zou, Hai-Feng Wu, Yu-Lian Tang, Di-Zhao Chen. A new labdane diterpene from the rhizomes of Alpinia officinarum. Natural product research. 2016; 30(1):1-6. doi: 10.1080/14786419.2015.1012717. [PMID: 26189919]
  • Hussain Arif, Nida Rehmani, Mohd Farhan, Aamir Ahmad, Sheikh Mumtaz Hadi. Mobilization of Copper ions by Flavonoids in Human Peripheral Lymphocytes Leads to Oxidative DNA Breakage: A Structure Activity Study. International journal of molecular sciences. 2015 Nov; 16(11):26754-69. doi: 10.3390/ijms161125992. [PMID: 26569217]
  • Chuanhong Wu, Jianxin Chen, Chang Chen, Wei Wang, Limei Wen, Kuo Gao, Xiuping Chen, Sihuai Xiong, Huihui Zhao, Shaojing Li. Wnt/β-catenin coupled with HIF-1α/VEGF signaling pathways involved in galangin neurovascular unit protection from focal cerebral ischemia. Scientific reports. 2015 Nov; 5(?):16151. doi: 10.1038/srep16151. [PMID: 26537366]
  • Ming-Shiun Tsai, Chia-Chih Chien, Ting-Hui Lin, Chia-Chi Liu, Rosa Huang Liu, Hong-Lin Su, Yung-Tsung Chiu, Sue-Hong Wang. Galangin Prevents Acute Hepatorenal Toxicity in Novel Propacetamol-Induced Acetaminophen-Overdosed Mice. Journal of medicinal food. 2015 Nov; 18(11):1187-97. doi: 10.1089/jmf.2014.3328. [PMID: 26501381]
  • Wei-hua Feng, Hang-hang Zhang, Yun Zhang, Ming Sun, Jun-long Niu. Determination of galangin in rat plasma by UPLC and pharmacokinetic study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2015 Aug; 998-999(?):26-30. doi: 10.1016/j.jchromb.2015.06.024. [PMID: 26149247]
  • Elena S Chernetsova, Gertrud E Morlock. Aspects of surface scanning by direct analysis in real time mass spectrometry employing plasma glow visualization. Rapid communications in mass spectrometry : RCM. 2015 Jul; 29(13):1242-52. doi: 10.1002/rcm.7221. [PMID: 26395608]
  • Ya-Nan Liu, Wang-Jian Zha, Yuan Ma, Fei-Fei Chen, Wen Zhu, Ai Ge, Xiao-Ning Zeng, Mao Huang. Galangin attenuates airway remodelling by inhibiting TGF-β1-mediated ROS generation and MAPK/Akt phosphorylation in asthma. Scientific reports. 2015 Jul; 5(?):11758. doi: 10.1038/srep11758. [PMID: 26156213]
  • Asimina Kerimi, Fadhilah Jailani, Gary Williamson. Modulation of cellular glucose metabolism in human HepG2 cells by combinations of structurally related flavonoids. Molecular nutrition & food research. 2015 May; 59(5):894-906. doi: 10.1002/mnfr.201400850. [PMID: 25712349]
  • Yearam Jung, Soon Young Shin, Yeonjoong Yong, Hyeryoung Jung, Seunghyun Ahn, Young Han Lee, Yoongho Lim. Plant-derived flavones as inhibitors of aurora B kinase and their quantitative structure-activity relationships. Chemical biology & drug design. 2015 May; 85(5):574-85. doi: 10.1111/cbdd.12445. [PMID: 25298094]
  • Petar Ristivojević, Jelena Trifković, Uroš Gašić, Filip Andrić, Nebojša Nedić, Živoslav Tešić, Dušanka Milojković-Opsenica. Ultrahigh-performance liquid chromatography and mass spectrometry (UHPLC-LTQ/Orbitrap/MS/MS) study of phenolic profile of Serbian poplar type propolis. Phytochemical analysis : PCA. 2015 Mar; 26(2):127-36. doi: 10.1002/pca.2544. [PMID: 25376949]
  • Qingqiong Luo, Liping Zhu, Jieying Ding, Xing Zhuang, Lili Xu, Fuxiang Chen. Protective effect of galangin in Concanavalin A-induced hepatitis in mice. Drug design, development and therapy. 2015; 9(?):2983-92. doi: 10.2147/dddt.s80979. [PMID: 26089647]
  • Shi-Xia Huo, Xin-Ming Liu, Chun-Hui Ge, Li Gao, Xiao-Ming Peng, Ping-Ping Zhao, Ming Yan. The effects of galangin on a mouse model of vitiligo induced by hydroquinone. Phytotherapy research : PTR. 2014 Oct; 28(10):1533-8. doi: 10.1002/ptr.5161. [PMID: 24820380]
  • Jin Kyeong Choi, Sang-Hyun Kim. Inhibitory effect of galangin on atopic dermatitis-like skin lesions. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2014 Jun; 68(?):135-41. doi: 10.1016/j.fct.2014.03.021. [PMID: 24675422]
  • Ragini Sinha, Sudha Srivastava, Akshada Joshi, Urmila J Joshi, Girjesh Govil. In-vitro anti-proliferative and anti-oxidant activity of galangin, fisetin and quercetin: role of localization and intermolecular interaction in model membrane. European journal of medicinal chemistry. 2014 May; 79(?):102-9. doi: 10.1016/j.ejmech.2014.04.002. [PMID: 24727463]
  • Fadhilah Jailani, Gary Williamson. Effect of edible oils on quercetin, kaempferol and galangin transport and conjugation in the intestinal Caco-2/HT29-MTX co-culture model. Food & function. 2014 Apr; 5(4):653-62. doi: 10.1039/c3fo60691k. [PMID: 24525490]
  • Meng-Qin Bian, Hong-Qing Wang, Jie Kang, Ruo-Yun Chen, Yan-Fang Yang, He-Zhen Wu. [Flavonoids from the seeds of Alpinia galanga Willd]. Yao xue xue bao = Acta pharmaceutica Sinica. 2014 Mar; 49(3):359-62. doi: . [PMID: 24961107]
  • Oluseye A Ogunbayo, Francesco Michelangeli. Related flavonoids cause cooperative inhibition of the sarcoplasmic reticulum Ca²⁺ ATPase by multimode mechanisms. The FEBS journal. 2014 Feb; 281(3):766-77. doi: 10.1111/febs.12621. [PMID: 24238016]
  • Jian Gao, Hongjun Yang, Jianxin Chen, Jiansong Fang, Chang Chen, Rixin Liang, Gengliang Yang, Hongwei Wu, Chuanhong Wu, Shaojing Li. Analysis of serum metabolites for the discovery of amino acid biomarkers and the effect of galangin on cerebral ischemia. Molecular bioSystems. 2013 Sep; 9(9):2311-21. doi: 10.1039/c3mb70040b. [PMID: 23793526]
  • Xinhui Wang, Guoqing Gong, Wenhui Yang, Yunzhan Li, Meiling Jiang, Linlin Li. Antifibrotic activity of galangin, a novel function evaluated in animal liver fibrosis model. Environmental toxicology and pharmacology. 2013 Sep; 36(2):288-295. doi: 10.1016/j.etap.2013.04.004. [PMID: 23686009]
  • Shiv Kumar, K R Alagawadi. Anti-obesity effects of galangin, a pancreatic lipase inhibitor in cafeteria diet fed female rats. Pharmaceutical biology. 2013 May; 51(5):607-13. doi: 10.3109/13880209.2012.757327. [PMID: 23363068]
  • Aleksandra V Pavlović, Dragana Č Dabić, Nebojša M Momirović, Biljana P Dojčinović, Dušanka M Milojković-Opsenica, Zivoslav Lj Tešić, Maja M Natić. Chemical composition of two different extracts of berries harvested in Serbia. Journal of agricultural and food chemistry. 2013 May; 61(17):4188-94. doi: 10.1021/jf400607f. [PMID: 23600608]
  • Van Trinh Thi Thanh, Huong Doan Thi Mai, Van Cuong Pham, Marc Litaudon, Vincent Dumontet, Françoise Guéritte, Van Hung Nguyen, Van Minh Chau. Acetylcholinesterase inhibitors from the leaves of Macaranga kurzii. Journal of natural products. 2012 Nov; 75(11):2012-5. doi: 10.1021/np300660y. [PMID: 23134335]
  • Shaojing Li, Chuanhong Wu, Li Zhu, Jian Gao, Jing Fang, Defeng Li, Meihong Fu, Rixin Liang, Lan Wang, Ming Cheng, Hongjun Yang. By improving regional cortical blood flow, attenuating mitochondrial dysfunction and sequential apoptosis galangin acts as a potential neuroprotective agent after acute ischemic stroke. Molecules (Basel, Switzerland). 2012 Nov; 17(11):13403-23. doi: 10.3390/molecules171113403. [PMID: 23143152]
  • Chang Hwa Jung, Soo Jeong Jang, Jiyun Ahn, So Young Gwon, Tae-Il Jeon, Tae Wan Kim, Tae Youl Ha. Alpinia officinarum inhibits adipocyte differentiation and high-fat diet-induced obesity in mice through regulation of adipogenesis and lipogenesis. Journal of medicinal food. 2012 Nov; 15(11):959-67. doi: 10.1089/jmf.2012.2286. [PMID: 23126661]
  • Miklós Poór, Sándor Kunsági-Máté, Tímea Bencsik, József Petrik, Sanda Vladimir-Knežević, Tamás Kőszegi. Flavonoid aglycones can compete with Ochratoxin A for human serum albumin: a new possible mode of action. International journal of biological macromolecules. 2012 Oct; 51(3):279-83. doi: 10.1016/j.ijbiomac.2012.05.019. [PMID: 22634515]