pichtosin (BioDeep_00000264726)

Main id: BioDeep_00000007628

Secondary id: BioDeep_00000395765

PANOMIX_OTCML-2023


代谢物信息卡片


(1S,2R,4S)-(-)-Bornyl acetate

化学式: C12H20O2 (196.1463)
中文名称: (-)-冰片醇乙酸酯, 乙酸异龙脑酯, （-）-乙酸硼酸酯, 异冰片，醋酸盐
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C12([C@]([H])(OC(=O)C)CC(CC1)C2(C)C)C
InChI: InChI=1S/C12H20O2/c1-8(13)14-10-7-9-5-6-12(10,4)11(9,2)3/h9-10H,5-7H2,1-4H3/t9-,10-,12+/m0/s1

描述信息

Flavour and fragrance ingredient [CCD]. (±)-Isobornyl acetate is found in spearmint and rosemary.
(-)-Bornyl acetate (L-(-)-Bornyl acetate), isolated from hyssop oil, is a less active enantiomer of (+)-Bornyl acetate. (-)-Bornyl acetate possesses antifungal activity[1].
(-)-Bornyl acetate (L-(-)-Bornyl acetate), isolated from hyssop oil, is a less active enantiomer of (+)-Bornyl acetate. (-)-Bornyl acetate possesses antifungal activity[1].
(-)-Bornyl acetate (L-(-)-Bornyl acetate), isolated from hyssop oil, is a less active enantiomer of (+)-Bornyl acetate. (-)-Bornyl acetate possesses antifungal activity[1].
(-)-Bornyl acetate (L-(-)-Bornyl acetate), isolated from hyssop oil, is a less active enantiomer of (+)-Bornyl acetate. (-)-Bornyl acetate possesses antifungal activity[1].

同义名列表

10 个代谢物同义名

(1S,2R,4S)-(-)-Bornyl acetate; (-)-Bornyl acetate; pichtosin; Isobornyl acetate; (±)-Isobornyl acetate; Isoborneol, acetate; L-(-)-Bornyl acetate; (1S,2R,4S)-(-)-Bornyl acetate; (-)-Bornyl acetate; Isoborneol, acetate



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ANXA5, CCL3, IL11, MAPK14, MAPK8, MARVELD1, PIK3C3, PIK3CA, PTGS2, TYR
Peripheral membrane protein 3 ACHE, ANXA5, PTGS2
Endoplasmic reticulum membrane 2 CD4, PTGS2
Cytoplasmic vesicle, autophagosome 1 PIK3C3
Nucleus 5 ACHE, MAPK14, MAPK8, MARVELD1, MPO
autophagosome 1 PIK3C3
cytosol 6 ANXA5, CCL3, MAPK14, MAPK8, PIK3C3, PIK3CA
phosphatidylinositol 3-kinase complex, class III 1 PIK3C3
nucleoplasm 3 MAPK14, MAPK8, MPO
Cell membrane 7 ACHE, CD4, CD86, ITGAM, MARVELD1, PTPRC, TNF
lamellipodium 1 PIK3CA
Multi-pass membrane protein 2 MARVELD1, MOG
Synapse 3 ACHE, MAPK8, PTPRC
cell surface 5 ACHE, CD86, ITGAM, PTPRC, TNF
glutamatergic synapse 2 MAPK14, PIK3C3
Golgi apparatus 2 ACHE, ATRN
neuromuscular junction 1 ACHE
neuronal cell body 1 TNF
sarcolemma 1 ANXA5
Lysosome 2 MPO, TYR
endosome 1 PIK3C3
plasma membrane 10 ACHE, ATRN, CD4, CD86, ITGAM, MARVELD1, MOG, PIK3CA, PTPRC, TNF
Membrane 8 ACHE, ANXA5, CD86, ITGAM, MARVELD1, MOG, PIK3C3, PTPRC
axon 1 MAPK8
caveola 1 PTGS2
extracellular exosome 6 ANXA5, ATRN, CD86, ITGAM, MPO, PTPRC
endoplasmic reticulum 1 PTGS2
extracellular space 8 ACHE, ATRN, CCL3, IL11, IL6, ITGAM, MPO, TNF
perinuclear region of cytoplasm 3 ACHE, PIK3CA, TYR
intercalated disc 1 PIK3CA
mitochondrion 1 MAPK14
protein-containing complex 1 PTGS2
intracellular membrane-bounded organelle 2 MPO, TYR
Microsome membrane 1 PTGS2
Single-pass type I membrane protein 7 ATRN, CD4, CD86, ITGAM, MOG, PTPRC, TYR
Secreted 4 ACHE, CCL3, IL11, IL6
extracellular region 8 ACHE, ANXA5, CCL3, IL11, IL6, MAPK14, MPO, TNF
cytoplasmic side of plasma membrane 1 PTPRC
[Isoform 2]: Secreted 1 ATRN
Extracellular side 1 ACHE
centriolar satellite 1 CD86
external side of plasma membrane 7 ANXA5, CD4, CD86, ITGAM, MOG, PTPRC, TNF
Melanosome membrane 1 TYR
midbody 1 PIK3C3
Early endosome 1 CD4
Golgi-associated vesicle 1 TYR
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 4 CD4, ITGAM, PTPRC, TNF
Cytoplasm, cytoskeleton 1 MARVELD1
focal adhesion 2 ANXA5, PTPRC
GABA-ergic synapse 1 PIK3C3
Peroxisome 1 PIK3C3
basement membrane 1 ACHE
collagen-containing extracellular matrix 1 ANXA5
secretory granule 1 MPO
axoneme 1 PIK3C3
nuclear speck 1 MAPK14
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Late endosome 1 PIK3C3
Zymogen granule membrane 1 ANXA5
neuron projection 1 PTGS2
phagocytic cup 1 TNF
phagocytic vesicle membrane 1 PIK3C3
cytoskeleton 1 MARVELD1
spindle pole 1 MAPK14
Lipid-anchor, GPI-anchor 1 ACHE
[Isoform 2]: Cell membrane 1 MOG
[Isoform 3]: Secreted 1 ATRN
phagophore assembly site 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type I 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type II 1 PIK3C3
specific granule membrane 1 ITGAM
tertiary granule membrane 1 ITGAM
Melanosome 1 TYR
side of membrane 1 ACHE
azurophil granule 1 MPO
plasma membrane raft 1 ITGAM
ficolin-1-rich granule lumen 1 MAPK14
secretory granule lumen 1 MAPK14
secretory granule membrane 1 PTPRC
endoplasmic reticulum lumen 3 CD4, IL6, PTGS2
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
azurophil granule lumen 1 MPO
presynaptic endosome 1 PIK3C3
vesicle membrane 1 ANXA5
clathrin-coated endocytic vesicle membrane 1 CD4
phagocytic vesicle lumen 1 MPO
synaptic cleft 1 ACHE
basal dendrite 1 MAPK8
[Isoform 1]: Cell membrane 2 ATRN, MOG
integrin complex 1 ITGAM
membrane microdomain 1 PTPRC
[Isoform 3]: Cell membrane 1 MOG
postsynaptic endosome 1 PIK3C3
bleb 1 PTPRC
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 1 CD4
Autolysosome 1 PIK3C3
integrin alphaM-beta2 complex 1 ITGAM
interleukin-6 receptor complex 1 IL6
[Isoform 6]: Cell membrane 1 MOG
[Isoform 7]: Cell membrane 1 MOG
endothelial microparticle 1 ANXA5
[Isoform 4]: Cell membrane 1 MOG
[Isoform 5]: Cell membrane 1 MOG
[Isoform 8]: Cell membrane 1 MOG
[Isoform H]: Cell membrane 1 ACHE
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[Isoform 9]: Cell membrane 1 MOG
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • L I Xiaohua, Duan Zhihang, Yue Jianjun, Zhang Yongyu, L I Yihang, Liu Shifang, Nie Qu, Yang Depo, Zhang Lixia. Bornyl acetate extracted from Sharen () inhibits proliferation, invasion and induces apoptosis by suppressing phosphatidylinositol-3-kinase/protein kinase B signaling in colorectal cancer. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 2023 Oct; 43(6):1081-1091. doi: 10.19852/j.cnki.jtcm.20231018.002. [PMID: 37946470]
  • Zhe-Jun Zhao, Yuan-Long Sun, Xiao-Fen Ruan. Bornyl acetate: A promising agent in phytomedicine for inflammation and immune modulation. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Mar; 114(?):154781. doi: 10.1016/j.phymed.2023.154781. [PMID: 37028250]
  • Yi-Xi Feng, Yang Wang, Zhu-Feng Geng, Di Zhang, Borjigidai Almaz, Shu-Shan Du. Contact toxicity and repellent efficacy of Valerianaceae spp. to three stored-product insects and synergistic interactions between two major compounds camphene and bornyl acetate. Ecotoxicology and environmental safety. 2020 Mar; 190(?):110106. doi: 10.1016/j.ecoenv.2019.110106. [PMID: 31877546]
  • Yi-Xi Feng, Yang Wang, Zhen-Yang Chen, Shan-Shan Guo, Chun-Xue You, Shu-Shan Du. Efficacy of bornyl acetate and camphene from Valeriana officinalis essential oil against two storage insects. Environmental science and pollution research international. 2019 Jun; 26(16):16157-16165. doi: 10.1007/s11356-019-05035-y. [PMID: 30972667]
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