Ana B (BioDeep_00000230010)
Main id: BioDeep_00000008321
PANOMIX_OTCML-2023
代谢物信息卡片
Benzoic acid, 2-hydroxy-6-(8-pentadecenyl)-, (Z)-
化学式: C22H34O3 (346.2508)
中文名称: 白果酸, 银杏酸, 银杏酸GA15:1
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C=C(CCCCCCC/C=C\CCCCCC)C(C(O)=O)=C(O)C=1
InChI: InChI=1S/C22H34O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-17-15-18-20(23)21(19)22(24)25/h7-8,15,17-18,23H,2-6,9-14,16H2,1H3,(H,24,25)/b8-7-
描述信息
Ginkgoic acid is a hydroxybenzoic acid. It is functionally related to a salicylic acid.
Ginkgolic acid is a natural product found in Amphipterygium adstringens, Anacardium occidentale, and other organisms with data available.
D000893 - Anti-Inflammatory Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D012459 - Salicylates
Ginkgolic Acid is a natural compound that inhibits SUMOylation with an IC50 of 3.0 μM in in vitro assay.
Ginkgolic Acid is a natural compound that inhibits SUMOylation with an IC50 of 3.0 μM in in vitro assay.
同义名列表
38 个代谢物同义名
Benzoic acid, 2-hydroxy-6-(8-pentadecenyl)-, (Z)-; (Z)-2-(heptadec-8-en-1-yl)-6-hydroxybenzoic acid; (Z)-2-Hydroxy-6-(pentadec-8-en-1-yl)benzoic acid; (Z)-2-(pentadec-8-en-1-yl)-6-hydroxybenzoic acid; Ginkgolic acid C15:1, primary reference standard; Benzoic acid, 2-hydroxy-6-(8Z)-8-pentadecenyl-; 2-hydroxy-6-[(Z)-pentadec-8-enyl]benzoic acid; (Z)-2-Hydroxy-6-(8-pentadecenyl)benzoic acid; 2-hydroxy-6-(pentadec-8-en-1-yl)benzoic acid; 2-Hydroxy-6-(8Z)-8-pentadecenylbenzoic acid; Ginkgolic acid C15:1, analytical standard; 6-((Z)-pentadec-8-en-1-yl)salicylic acid; 6-((Z)-heptadec-8-en-1-yl)salicylic acid; 6-[8(Z)-pentadecatrienyl]salicylic acid; Ginkgolic Acid (15:1) - CAS 22910-60-7; 6-[(8Z)-Pentadecenyl]-salicylic acid; 6-{8(Z)-pentadecenyl}salicylic acid; 6[8(Z )-Pentadecenyl]Salicylic Acid; 6-[8(Z)-pentadecenyl]salicylic acid; 6[8(Z )-pentadecenyl]salicylic acid; 6-(8Z)-Pentadecenylsalicylic acid; 6-(8Z-pentadecenyl)-salicylicacid; Anacardic acid 8Z-monoene; Anacardic Acid 8Z-Monoene; Anacardic acid monoene; (15:1)-Anacardic acid; Ginkgolic acid (15:1); Ginkgolic acid C15:1; Ginkgolic acid 15:1; Romanicardic acid; Ginkgolic acid I; Spectrum5_000899; Gingkolic Acid; Ginkgolic acid; Ginkgoic acid; Ginkgolic; Ana B; Ginkgoic acid
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:193466
- ChEBI: CHEBI:5354
- KEGG: C10794
- PubChem: 5281858
- ChEMBL: CHEMBL445177
- LipidMAPS: LMPK15040003
- MeSH: ginkgolic acid
- ChemIDplus: 0022910607
- KNApSAcK: C00002651
- chemspider: 4445152
- CAS: 22910-60-7
- medchemexpress: HY-N0077
- PubChem: 12977
- 3DMET: B04128
- NIKKAJI: J15.322B
- RefMet: Ginkgolic acid
- KNApSAcK: 5354
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
11 个相关的物种来源信息
- 124857 - Amphipterygium adstringens: 10.1080/14786419.2010.534996
- 171929 - Anacardium occidentale: 10.1021/JF00030A035
- 210348 - Brucea javanica: 10.1002/JCCS.200500117
- 3311 - Ginkgo biloba:
- 3311 - Ginkgo biloba L.: -
- 224862 - Knema laurina: 10.1016/S0031-9422(96)00413-X
- 375255 - Myrcia multiflora: 10.1248/CPB.46.113
- 289735 - Ozoroa insignis: 10.1016/J.FITOTE.2003.08.007
- 33090 - Plants: -
- 33090 - 白果: -
- 3311 - 银杏叶: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jinchao Wei, Renjian Xu, Yuanyuan Zhang, Lingyu Zhao, Shumu Li, Zhenwen Zhao. Ultra-High-Performance Liquid Chromatography-Electrospray Ionization-High-Resolution Mass Spectrometry for Distinguishing the Origin of Ellagic Acid Extracts: Pomegranate Peels or Gallnuts.
Molecules (Basel, Switzerland).
2024 Jan; 29(3):. doi:
10.3390/molecules29030666. [PMID: 38338410] - Yusen Xiang, Guanglei Zhai, Yaozong Li, Mengge Wang, Xixiang Chen, Ruyu Wang, Hang Xie, Weidong Zhang, Guangbo Ge, Qian Zhang, Yechun Xu, Amedeo Caflisch, Jianrong Xu, Hongzhuan Chen, Lili Chen. Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay.
International journal of biological macromolecules.
2023 Jan; 226(?):780-792. doi:
10.1016/j.ijbiomac.2022.12.057. [PMID: 36521705] - Xiaojia Su, Ruirui Shi, Haiyan Hu, Linfeng Hu, Qichao Wei, Yuanyuan Guan, Jingling Chang, Chengwei Li. Medicinal Values and Potential Risks Evaluation of Ginkgo biloba Leaf Extract (GBE) Drinks Made from the Leaves in Autumn as Dietary Supplements.
Molecules (Basel, Switzerland).
2022 Nov; 27(21):. doi:
10.3390/molecules27217479. [PMID: 36364306] - Isaac Duah Boateng. A critical review of ginkgolic acids in Ginkgo biloba leaf extract (EGb): toxicity and technologies to remove ginkgolic acids and their promising bioactivities.
Food & function.
2022 Sep; 13(18):9226-9242. doi:
10.1039/d2fo01827f. [PMID: 36065842] - Isaac Duah Boateng. A critical review of current technologies used to reduce ginkgotoxin, ginkgotoxin-5'-glucoside, ginkgolic acid, allergic glycoprotein, and cyanide in Ginkgo biloba L. seed.
Food chemistry.
2022 Jul; 382(?):132408. doi:
10.1016/j.foodchem.2022.132408. [PMID: 35176549] - Zewen Wen, Yuxi Zhao, Zhengyang Gong, Yuanyuan Tang, Yanpeng Xiong, Junwen Chen, Chengchun Chen, Yufang Zhang, Shanghong Liu, Jinxin Zheng, Duoyun Li, Qiwen Deng, Zhijian Yu. The Mechanism of Action of Ginkgolic Acid (15:1) against Gram-Positive Bacteria Involves Cross Talk with Iron Homeostasis.
Microbiology spectrum.
2022 02; 10(1):e0099121. doi:
10.1128/spectrum.00991-21. [PMID: 35019708] - Hong-Mei Li, Hui Ma, Xiaolong Sun, Bohan Li, Chengjiang Cao, Yiqun Dai, Meilin Zhu, Cheng-Zhu Wu. Anti-Cancer Properties of Ginkgolic Acids in Human Nasopharyngeal Carcinoma CNE-2Z Cells via Inhibition of Heat Shock Protein 90.
Molecules (Basel, Switzerland).
2021 Oct; 26(21):. doi:
10.3390/molecules26216575. [PMID: 34770993] - Yuan Xiong, Guang-Hao Zhu, Hao-Nan Wang, Qing Hu, Li-Li Chen, Xiao-Qing Guan, Hui-Liang Li, Hong-Zhuan Chen, Hui Tang, Guang-Bo Ge. Discovery of naturally occurring inhibitors against SARS-CoV-2 3CLpro from Ginkgo biloba leaves via large-scale screening.
Fitoterapia.
2021 Jul; 152(?):104909. doi:
10.1016/j.fitote.2021.104909. [PMID: 33894315] - Hung-Yueh Chen, Yuwen Ting, Hsing-Chun Kuo, Chang-Wei Hsieh, Hsien-Yi Hsu, Chun-Nan Wu, Kuan-Chen Cheng. Enzymatic degradation of ginkgolic acids by laccase immobilized on core/shell Fe3O4/nylon composite nanoparticles using novel coaxial electrospraying process.
International journal of biological macromolecules.
2021 Mar; 172(?):270-280. doi:
10.1016/j.ijbiomac.2021.01.004. [PMID: 33418049] - Piotr Migas, Anna Romańczuk, Marta Szumacher, Mirosława Krauze-Baranowska. Application of targeted 2D planar chromatography in the control of ginkgolic acids in some herbal drugs and dietary supplements.
Acta pharmaceutica (Zagreb, Croatia).
2020 Jun; 70(2):201-213. doi:
10.2478/acph-2020-0004. [PMID: 31955143] - Hung-Yueh Chen, Kuan-Chen Cheng, Ren-Jun Hsu, Chang-Wei Hsieh, Hsueh-Ting Wang, Yuwen Ting. Enzymatic degradation of ginkgolic acid by laccase immobilized on novel electrospun nanofiber mat.
Journal of the science of food and agriculture.
2020 Apr; 100(6):2705-2712. doi:
10.1002/jsfa.10301. [PMID: 32003007] - Muhamad Aqmal Othman, Kohei Yuyama, Yuta Murai, Yasuyuki Igarashi, Daisuke Mikami, Yasodha Sivasothy, Khalijah Awang, Kenji Monde. Malabaricone C as Natural Sphingomyelin Synthase Inhibitor against Diet-Induced Obesity and Its Lipid Metabolism in Mice.
ACS medicinal chemistry letters.
2019 Aug; 10(8):1154-1158. doi:
10.1021/acsmedchemlett.9b00171. [PMID: 31413799] - Yiyun Qian, Shulan Su, Min Wei, Zhenhua Zhu, Sheng Guo, Hui Yan, Jinhua Tao, Dawei Qian, Jin-Ao Duan. Interactions of pharmacokinetic profiles of Ginkgotoxin and Ginkgolic acids in rat plasma after oral administration.
Journal of pharmaceutical and biomedical analysis.
2019 Jan; 163(?):88-94. doi:
10.1016/j.jpba.2018.09.053. [PMID: 30286439] - Heng Zhu, Hailong Jiang, Jinqian Yu, Xiangyun Song, Hengqiang Zhao, Jingchao Li, Yanling Geng, Daijie Wang. Application of coordination agent in high-speed counter-current chromatography for the preparative separation and isolation ginkgolic acids from the sarcotesta of Ginkgo biloba L.
Journal of separation science.
2018 Dec; 41(23):4379-4386. doi:
10.1002/jssc.201800637. [PMID: 30302914] - Mahadeva M M Swamy, Yuta Murai, Yusuke Ohno, Keisuke Jojima, Akio Kihara, Susumu Mitsutake, Yasuyuki Igarashi, Jian Yu, Min Yao, Yoshiko Suga, Masaki Anetai, Kenji Monde. Structure-inspired design of a sphingolipid mimic sphingosine-1-phosphate receptor agonist from a naturally occurring sphingomyelin synthase inhibitor.
Chemical communications (Cambridge, England).
2018 Nov; 54(90):12758-12761. doi:
10.1039/c8cc05595e. [PMID: 30362470] - Qing-Qing Yao, Li Li, Ming-Cheng Xu, Hai-Hong Hu, Hui Zhou, Lu-Shan Yu, Su Zeng. The metabolism and hepatotoxicity of ginkgolic acid (17 : 1) in vitro.
Chinese journal of natural medicines.
2018 Nov; 16(11):829-837. doi:
10.1016/s1875-5364(18)30124-9. [PMID: 30502764] - Yuxia Liu, Bin Yang, Lirong Zhang, Xianling Cong, Zhen Liu, Yu Hu, Jing Zhang, Haixia Hu. Ginkgolic acid induces interplay between apoptosis and autophagy regulated by ROS generation in colon cancer.
Biochemical and biophysical research communications.
2018 03; 498(1):246-253. doi:
10.1016/j.bbrc.2018.01.091. [PMID: 29353042] - Zhongping Huang, Yueting Xu, Yilei Huang, Charles Liu, Kezhi Jiang, Lili Wang. Rapid determination of ginkgolic acids in Ginkgo biloba kernels and leaves by direct analysis in real time-mass spectrometry.
Journal of separation science.
2017 Dec; 40(24):4857-4864. doi:
10.1002/jssc.201700626. [PMID: 29134743] - Yiyun Qian, Yunru Peng, Erxin Shang, Ming Zhao, Liang Yan, Zhenhua Zhu, Jinhua Tao, Shulan Su, Sheng Guo, Jin-Ao Duan. Metabolic profiling of the hepatotoxicity and nephrotoxicity of Ginkgolic acids in rats using ultra-performance liquid chromatography-high-definition mass spectrometry.
Chemico-biological interactions.
2017 Aug; 273(?):11-17. doi:
10.1016/j.cbi.2017.05.020. [PMID: 28564578] - Qing-Qing Yao, Zhen-Hua Liu, Ming-Cheng Xu, Hai-Hong Hu, Hui Zhou, Hui-Di Jiang, Lu-Shan Yu, Su Zeng. Mechanism for ginkgolic acid (15 : 1)-induced MDCK cell necrosis: Mitochondria and lysosomes damages and cell cycle arrest.
Chinese journal of natural medicines.
2017 May; 15(5):375-383. doi:
10.1016/s1875-5364(17)30058-4. [PMID: 28558873] - Lei Jiang, Zhi-Hong Si, Ming-Hui Li, He Zhao, Yong-Hong Fu, Yue-Xiao Xing, Wei Hong, Ling-Yu Ruan, Pu-Min Li, Jun-Song Wang. 1H NMR-based metabolomics study of liver damage induced by ginkgolic acid (15:1) in mice.
Journal of pharmaceutical and biomedical analysis.
2017 Mar; 136(?):44-54. doi:
10.1016/j.jpba.2016.12.033. [PMID: 28063335] - Seung Ho Baek, Jong Hyun Lee, Chulwon Kim, Jeong-Hyeon Ko, Seung-Hee Ryu, Seok-Geun Lee, Woong Mo Yang, Jae-Young Um, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Gautam Sethi, Kwang Seok Ahn. Ginkgolic Acid C 17:1, Derived from Ginkgo biloba Leaves, Suppresses Constitutive and Inducible STAT3 Activation through Induction of PTEN and SHP-1 Tyrosine Phosphatase.
Molecules (Basel, Switzerland).
2017 Feb; 22(2):. doi:
10.3390/molecules22020276. [PMID: 28208828] - Yiyun Qian, Zhenhua Zhu, Jin-Ao Duan, Sheng Guo, Erxin Shang, Jinhua Tao, Shulan Su, Jianming Guo. Simultaneous quantification and semi-quantification of ginkgolic acids and their metabolites in rat plasma by UHPLC-LTQ-Orbitrap-MS and its application to pharmacokinetics study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Jan; 1041-1042(?):85-93. doi:
10.1016/j.jchromb.2016.11.038. [PMID: 28013179] - Zhebin Hua, Caie Wu, Gongjian Fan, Zhenxing Tang, Fuliang Cao. The antibacterial activity and mechanism of ginkgolic acid C15:1.
BMC biotechnology.
2017 01; 17(1):5. doi:
10.1186/s12896-016-0324-3. [PMID: 28088196] - Mei Wang, Emily J Carrell, Amar G Chittiboyina, Bharathi Avula, Yan-Hong Wang, Jianping Zhao, Jon F Parcher, Ikhlas A Khan. Concurrent supercritical fluid chromatographic analysis of terpene lactones and ginkgolic acids in Ginkgo biloba extracts and dietary supplements.
Analytical and bioanalytical chemistry.
2016 Jul; 408(17):4649-60. doi:
10.1007/s00216-016-9544-6. [PMID: 27129974] - Jian Sun, Limin Li, Qing Hu, Xiuhong Mao, Shen Ji. [Determination of ginkgolic acids in the ginkgo biloba extract and its preparations by ultra high performance liquid chromatography-triple quadrupole mass spectrometry].
Se pu = Chinese journal of chromatography.
2016 Feb; 34(2):184-8. doi:
10.3724/sp.j.1123.2015.08027. [PMID: 27382724] - G Maleeva, S Buldakova, P Bregestovski. [SUBUNIT SPECIFIC MODULATION OF GLYCINE RECEPTORS BY GINKGOLIC ACID.].
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994).
2016; 62(4):40-45. doi:
10.15407/fz62.04.040. [PMID: 29975473] - Wen Zheng, Ximin Li, Lin Zhang, Yanzhen Zhang, Xiaoping Lu, Jingkui Tian. Improved metabolites of pharmaceutical ingredient grade Ginkgo biloba and the correlated proteomics analysis.
Proteomics.
2015 Jun; 15(11):1868-83. doi:
10.1002/pmic.201400258. [PMID: 25604066] - Chunyuan Guo, Qingqing Wei, Yunchao Su, Zheng Dong. SUMOylation occurs in acute kidney injury and plays a cytoprotective role.
Biochimica et biophysica acta.
2015 Mar; 1852(3):482-9. doi:
10.1016/j.bbadis.2014.12.013. [PMID: 25533125] - Kerstin Berg, Christine Braun, Isabel Krug, Dieter Schrenk. Evaluation of the cytotoxic and mutagenic potential of three ginkgolic acids.
Toxicology.
2015 Jan; 327(?):47-52. doi:
10.1016/j.tox.2014.10.001. [PMID: 25448085] - Ruwei Wang, Yuta Kobayashi, Yu Lin, Hans Wilhelm Rauwald, Jianbiao Yao, Ling Fang, Hongxiang Qiao, Kenny Kuchta. HPLC quantification of all five ginkgolic acid derivatives in Ginkgo biloba extracts using 13 : 0 ginkgolic acid as a single marker compound.
Planta medica.
2015 Jan; 81(1):71-8. doi:
10.1055/s-0034-1383312. [PMID: 25519835] - Mei Wang, Jianping Zhao, Bharathi Avula, Yan-Hong Wang, Cristina Avonto, Amar G Chittiboyina, Philip L Wylie, Jon F Parcher, Ikhlas A Khan. High-resolution gas chromatography/mass spectrometry method for characterization and quantitative analysis of ginkgolic acids in Ginkgo biloba plants, extracts, and dietary supplements.
Journal of agricultural and food chemistry.
2014 Dec; 62(50):12103-11. doi:
10.1021/jf503980f. [PMID: 25383633] - Irini Tossidou, Erik Himmelseher, Beina Teng, Hermann Haller, Mario Schiffer. SUMOylation determines turnover and localization of nephrin at the plasma membrane.
Kidney international.
2014 Dec; 86(6):1161-73. doi:
10.1038/ki.2014.198. [PMID: 24940800] - Wenhua Ji, Xiuli Ma, Hongkai Xie, Lingxiao Chen, Xiao Wang, Hengqiang Zhao, Luqi Huang. Molecularly imprinted polymers with synthetic dummy template for simultaneously selective removal and enrichment of ginkgolic acids from Ginkgo biloba L. leaves extracts.
Journal of chromatography. A.
2014 Nov; 1368(?):44-51. doi:
10.1016/j.chroma.2014.09.070. [PMID: 25441343] - Li Li, Qing-Qing Yao, Si-Yun Xu, Hai-Hong Hu, Qi Shen, Ye Tian, Lan-Ying Pan, Hui Zhou, Hui-di Jiang, Chuang Lu, Lu-Shan Yu, Su Zeng. Cyclosporin A affects the bioavailability of ginkgolic acids via inhibition of P-gp and BCRP.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2014 Nov; 88(3):759-67. doi:
10.1016/j.ejpb.2014.06.012. [PMID: 24980806] - Agus Sukito, Sanro Tachibana. Potent α-glucosidase inhibitors isolated from Ginkgo biloba leaves.
Pakistan journal of biological sciences : PJBS.
2014 Nov; 17(11):1170-8. doi:
10.3923/pjbs.2014.1170.1178. [PMID: 26027162] - Renkai Li, Yao Shen, Xiaojuan Zhang, Ming Ma, Bo Chen, Teris A van Beek. Efficient purification of ginkgolic acids from Ginkgo biloba leaves by selective adsorption on Fe3O4 magnetic nanoparticles.
Journal of natural products.
2014 Mar; 77(3):571-5. doi:
10.1021/np400821r. [PMID: 24484321] - Jin-Hyung Lee, Yong-Guy Kim, Shi Yong Ryu, Moo Hwan Cho, Jintae Lee. Ginkgolic acids and Ginkgo biloba extract inhibit Escherichia coli O157:H7 and Staphylococcus aureus biofilm formation.
International journal of food microbiology.
2014 Mar; 174(?):47-55. doi:
10.1016/j.ijfoodmicro.2013.12.030. [PMID: 24457153] - Jianbo Chen, Suqin Sun, Qun Zhou. Direct observation of bulk and surface chemical morphologies of Ginkgo biloba leaves by Fourier transform mid- and near-infrared microspectroscopic imaging.
Analytical and bioanalytical chemistry.
2013 Nov; 405(29):9385-400. doi:
10.1007/s00216-013-7366-3. [PMID: 24091737] - Christian Ude, Manfred Schubert-Zsilavecz, Mario Wurglics. Ginkgo biloba extracts: a review of the pharmacokinetics of the active ingredients.
Clinical pharmacokinetics.
2013 Sep; 52(9):727-49. doi:
10.1007/s40262-013-0074-5. [PMID: 23703577] - Yuanqing Fu, Shan Hong, Duo Li, Songbai Liu. Novel chemical synthesis of ginkgolic acid (13:0) and evaluation of its tyrosinase inhibitory activity.
Journal of agricultural and food chemistry.
2013 Jun; 61(22):5347-52. doi:
10.1021/jf4012642. [PMID: 23701207] - Joonseok Oh, In Hyun Hwang, Chang-Eui Hong, Su-Yun Lyu, MinKyun Na. Inhibition of fatty acid synthase by ginkgolic acids from the leaves of Ginkgo biloba and their cytotoxic activity.
Journal of enzyme inhibition and medicinal chemistry.
2013 Jun; 28(3):565-8. doi:
10.3109/14756366.2012.658786. [PMID: 22380770] - Elaine C Cabral, Mario F Mirabelli, Consuelo J Perez, Demian R Ifa. Blotting assisted by heating and solvent extraction for DESI-MS imaging.
Journal of the American Society for Mass Spectrometry.
2013 Jun; 24(6):956-65. doi:
10.1007/s13361-013-0616-y. [PMID: 23605686] - Hongjun Xia, Zhenhua Liu, Haihong Hu, Hui Zhou, Su Zeng. Identification of ginkgolic acid (15:1) metabolites in rats following oral administration by high-performance liquid chromatography coupled to tandem mass spectrometry.
Xenobiotica; the fate of foreign compounds in biological systems.
2013 May; 43(5):454-60. doi:
10.3109/00498254.2012.725141. [PMID: 23205533] - Xin Yao, Gui-Sheng Zhou, Yu-Ping Tang, Ye-Fei Qian, Han-Liang Guan, Hanqing Pang, Shaoqing Zhu, Xuan Mo, Shu-Lan Su, Chun Jin, Yong Qin, Da-Wei Qian, Jin-Ao Duan. Simultaneous quantification of flavonol glycosides, terpene lactones, biflavones, proanthocyanidins, and ginkgolic acids in Ginkgo biloba leaves from fruit cultivars by ultrahigh-performance liquid chromatography coupled with triple quadrupole mass spectrometry.
BioMed research international.
2013; 2013(?):582591. doi:
10.1155/2013/582591. [PMID: 23533996] - Jian-Ming Lü, Shaoyu Yan, Saha Jamaluddin, Sarah M Weakley, Zhengdong Liang, Edward B Siwak, Qizhi Yao, Changyi Chen. Ginkgolic acid inhibits HIV protease activity and HIV infection in vitro.
Medical science monitor : international medical journal of experimental and clinical research.
2012 Aug; 18(8):BR293-298. doi:
10.12659/msm.883261. [PMID: 22847190] - Maciej A Pszczolkowski, Kevin Durden, Samantha Sellars, Brian Cowell, John J Brown. Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.
Journal of agricultural and food chemistry.
2011 Oct; 59(20):10879-86. doi:
10.1021/jf202386c. [PMID: 21905729] - Hongjun Xia, Xiaodan Wang, Li Li, Shengjia Wang, Changchuan Guo, Yao Liu, Lushan Yu, Huidi Jiang, Su Zeng. Development of high performance liquid chromatography/electrospray ionization mass spectrometry for assay of ginkgolic acid (15:1) in rat plasma and its application to pharmacokinetics study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2010 Oct; 878(28):2701-6. doi:
10.1016/j.jchromb.2010.08.009. [PMID: 20829122] - Chen-chen Zhou, Wei Du, Zong Wen, Ji-yao Li, Ping Zhang. [Effects of natural plant ginkgolic acids on the apoptosis of human Hep-2 cancer cells].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition.
2009 May; 40(3):459-61. doi:
". [PMID: 19627005] - Jianming Ju, Yiping Huang, Shihui Qian, Dawei Qian, Jin'ao Duan, Fuliang Cao. [Studies on dynamic change of total ginkgolic acids in Ginkgo biloba leaves of different aged trees and different collecting seasons].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2009 Apr; 34(7):817-9. doi:
". [PMID: 19623970] - Isao Fukuda, Akihiro Ito, Go Hirai, Shinichi Nishimura, Hisashi Kawasaki, Hisato Saitoh, Ken-Ichi Kimura, Mikiko Sodeoka, Minoru Yoshida. Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate.
Chemistry & biology.
2009 Feb; 16(2):133-40. doi:
10.1016/j.chembiol.2009.01.009. [PMID: 19246003] - Lili Wang, Yilü Jia, Zaifa Pan, Hongxing Xu, Xusong Zheng, Zhongxian Lü. [Determination of ginkgolic acids in Ginkgo biloba leaves by gas chromatography with on-line pyrolytic methylation].
Se pu = Chinese journal of chromatography.
2008 Nov; 26(6):731-5. doi:
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