N-Acetylornithine (BioDeep_00000229686)
Main id: BioDeep_00000001392
human metabolite PANOMIX_OTCML-2023
代谢物信息卡片
N-alpha-Acetyl-L-ornithine
化学式: C7H14N2O3 (174.1004)
中文名称: N-alpha-乙酰基-L-鸟氨酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)NC(CCCN)C(=O)O
InChI: InChI=1S/C7H14N2O3/c1-5(10)9-6(7(11)12)3-2-4-8/h6H,2-4,8H2,1H3,(H,9,10)(H,11,12)/t6-/m0/s1
描述信息
N-Acetylornithine is an intermediate in the enzymatic biosynthesis of the amino acid L-arginine from L-glutamate.
同义名列表
分类词条
相关代谢途径
Reactome(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Shengyuan Luo, Aditya Surapaneni, Zihe Zheng, Eugene P Rhee, Josef Coresh, Adriana M Hung, Girish N Nadkarni, Bing Yu, Eric Boerwinkle, Adrienne Tin, Dan E Arking, Inga Steinbrenner, Pascal Schlosser, Anna Köttgen, Morgan E Grams. NAT8 Variants, N-Acetylated Amino Acids, and Progression of CKD.
Clinical journal of the American Society of Nephrology : CJASN.
2020 12; 16(1):37-47. doi:
10.2215/cjn.08600520. [PMID: 33380473] - Nanxiang Xiong, Xiaofei Gao, Hongyang Zhao, Feng Cai, Fang-Cheng Zhang, Ye Yuan, Weichao Liu, Fangping He, Lauren G Zacharias, Hong Lin, Hieu S Vu, Chao Xing, Dong-Xiao Yao, Fei Chen, Benyan Luo, Wenzhi Sun, Ralph J DeBerardinis, Hao Xu, Woo-Ping Ge. Using arterial-venous analysis to characterize cancer metabolic consumption in patients.
Nature communications.
2020 06; 11(1):3169. doi:
10.1038/s41467-020-16810-8. [PMID: 32576825] - Sarita Devi, Bajanai Nongkhlaw, M Limesh, Roshni M Pasanna, Tinku Thomas, Rebecca Kuriyan, Anura V Kurpad, Arpita Mukhopadhyay. Acyl ethanolamides in Diabetes and Diabetic Nephropathy: Novel targets from untargeted plasma metabolomic profiles of South Asian Indian men.
Scientific reports.
2019 12; 9(1):18117. doi:
10.1038/s41598-019-54584-2. [PMID: 31792390] - Eleonora Napoli, Andrea Schneider, Jun Yi Wang, Aditi Trivedi, Nika Roa Carrillo, Flora Tassone, Michael Rogawski, Randi J Hagerman, Cecilia Giulivi. Allopregnanolone Treatment Improves Plasma Metabolomic Profile Associated with GABA Metabolism in Fragile X-Associated Tremor/Ataxia Syndrome: a Pilot Study.
Molecular neurobiology.
2019 May; 56(5):3702-3713. doi:
10.1007/s12035-018-1330-3. [PMID: 30187385] - Dorottya Nagy-Szakal, Dinesh K Barupal, Bohyun Lee, Xiaoyu Che, Brent L Williams, Ellie J R Kahn, Joy E Ukaigwe, Lucinda Bateman, Nancy G Klimas, Anthony L Komaroff, Susan Levine, Jose G Montoya, Daniel L Peterson, Bruce Levin, Mady Hornig, Oliver Fiehn, W Ian Lipkin. Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics.
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10.1038/s41598-018-28477-9. [PMID: 29968805] - Barbara Molesini, Serena Zanzoni, Giuseppe Mennella, Gianluca Francese, Alessia Losa, Giuseppe L Rotino, Tiziana Pandolfini. The Arabidopsis N-Acetylornithine Deacetylase Controls Ornithine Biosynthesis via a Linear Pathway with Downstream Effects on Polyamine Levels.
Plant & cell physiology.
2017 01; 58(1):130-144. doi:
10.1093/pcp/pcw167. [PMID: 28064246] - Ziming Lu, Wuxing Sun, Xuhong Duan, Zhiyun Yang, Yadong Liu, Pengfei Tu. [Chemical constituents from Corydalis yanhusuo].
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BMC microbiology.
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BMC genomics.
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10.1186/1471-2164-12-268. [PMID: 21615926] - Naruo Nikoh, Takahiro Hosokawa, Kenshiro Oshima, Masahira Hattori, Takema Fukatsu. Reductive evolution of bacterial genome in insect gut environment.
Genome biology and evolution.
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10.1093/gbe/evr064. [PMID: 21737395] - Alain Perret, Christophe Lechaplais, Sabine Tricot, Nadia Perchat, Carine Vergne, Christine Pellé, Karine Bastard, Annett Kreimeyer, David Vallenet, Anne Zaparucha, Jean Weissenbach, Marcel Salanoubat. A novel acyl-CoA beta-transaminase characterized from a metagenome.
PloS one.
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PLoS pathogens.
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2009 Oct; 9(?):217. doi:
10.1186/1471-2180-9-217. [PMID: 19825185] - Shawn M Clark, Rosa Di Leo, Preetinder K Dhanoa, Owen R Van Cauwenberghe, Robert T Mullen, Barry J Shelp. Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis gamma-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate.
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