Gene Association: ATP1B4

UniProt Search: ATP1B4 (PROTEIN_CODING)
Function Description: ATPase Na+/K+ transporting family member beta 4

found 7 associated metabolites with current gene based on the text mining result from the pubmed database.

N-alpha-acetylornithine

(2S)-5-Amino-2-acetamidopentanoic acid

C7H14N2O3 (174.1004)


N2-Acetylornithine, also known as N(alpha)-acetylornithine, belongs to the class of organic compounds known as N-acyl-L-alpha-amino acids. These are N-acylated alpha-amino acids which have the L-configuration of the alpha-carbon atom. N-Acetylornithine is a minor component of the deproteinized blood plasma of human blood. Human blood plasma contains a variable amount of acetylornithine, averaging 1.1 +/- 0.4 umol/L (range 0.8-0.2 umol/L). Urine contains a very small amount of acetylornithine, approximately 1 nmol/mg creatinine (1 umol/day) (PMID:508804). Acquisition and generation of the data is financially supported in part by CREST/JST. CONFIDENCE standard compound; INTERNAL_ID 160 KEIO_ID A032 N-Acetylornithine is an intermediate in the enzymatic biosynthesis of the amino acid L-arginine from L-glutamate.

   

N-Succinyl-2-amino-6-ketopimelate

(2S)-2-(3-carboxypropanamido)-6-Oxoheptanedioic acid

C11H15NO8 (289.0798)


N-Succinyl-2-amino-6-ketopimelate is an intermediate in lysine biosynthesis. It is the fourth to last step in the synthesis of lysine and is converted. from tetrahydrodipicolinate via the enzyme tetrahydrodipicolinate N-succinyltransferase (EC 2.3.1.117). It is then converted to N-succinyl-L,L-2,6-diaminopimelate via the enzyme Succinyldiaminopimelate transferase (EC 2.6.1.17). N-Succinyl-2-amino-6-ketopimelate is an intermediate in lysine biosynthesis. It is the fourth to last step in the synthesis of lysine and is converted

   

3-Amino-2,3-dihydrobenzoic acid

5-Amino-1,3-cyclohexadiene-1-carboxylic acid

C7H9NO2 (139.0633)


D004791 - Enzyme Inhibitors

   

N-Acetylornithine

N-alpha-Acetyl-L-ornithine

C7H14N2O3 (174.1004)


N-Acetylornithine is an intermediate in the enzymatic biosynthesis of the amino acid L-arginine from L-glutamate.

   

N-Acetylornithine

N-alpha-Acetyl-L-ornithine

C7H14N2O3 (174.1004)


N-Acetylornithine is an intermediate in the enzymatic biosynthesis of the amino acid L-arginine from L-glutamate.

   

(2S)-2-(3-carboxypropanamido)-6-Oxoheptanedioic acid

(2S)-2-(3-carboxypropanamido)-6-Oxoheptanedioic acid

C11H15NO8 (289.0798)


   

gabaculine

3-Amino-2,3-dihydrobenzoic acid

C7H9NO2 (139.0633)


D004791 - Enzyme Inhibitors