beta-Mercaptoethanol (BioDeep_00000004521)
Secondary id: BioDeep_00001867649
human metabolite blood metabolite BioNovoGene_Lab2019
代谢物信息卡片
2-sulfanylethan-1-ol
化学式: C2H6OS (78.0139)
中文名称: 巯基乙醇, β-巯基乙醇
谱图信息:
最多检出来源 Homo sapiens(blood) 53.95%
分子结构信息
SMILES: C(CS)O
InChI: InChI=1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2
数据库引用编号
19 个数据库交叉引用编号
- ChEBI: CHEBI:41218
- KEGG: C00928
- PubChem: 1567
- HMDB: HMDB0245190
- Metlin: METLIN65543
- DrugBank: DB03345
- ChEMBL: CHEMBL254951
- Wikipedia: 2-Mercaptoethanol
- MeSH: Mercaptoethanol
- chemspider: 1512
- CAS: 155613-89-1
- CAS: 60-24-2
- PMhub: MS000017026
- PubChem: 4181
- PDB-CCD: BME
- 3DMET: B00201
- NIKKAJI: J1.396J
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-823
- KNApSAcK: 41218
分类词条
相关代谢途径
BioCyc(41)
- alkylnitronates degradation
- superpathway of demethylmenaquinol-8 biosynthesis I
- 2-carboxy-1,4-naphthoquinol biosynthesis
- superpathway of menaquinol-8 biosynthesis I
- superpathway of chorismate metabolism
- hordatine biosynthesis
- urea cycle
- superpathway of L-citrulline metabolism
- L-citrulline biosynthesis
- superpathway of pentose and pentitol degradation
- superpathway of microbial D-galacturonate and D-glucuronate degradation
- superpathway of CMP-sialic acids biosynthesis
- superpathway of glycerol degradation to 1,3-propanediol
- superpathway of L-lysine degradation
- L-lysine fermentation to acetate and butanoate
- N10-formyl-tetrahydrofolate biosynthesis
- esculetin modification
- superpathway of scopolin and esculin biosynthesis
- galactose degradation I (Leloir pathway)
- D-galactose degradation I (Leloir pathway)
- lactose degradation III
- melibiose degradation
- sanguinarine and macarpine biosynthesis
- CMP-N-acetylneuraminate biosynthesis I (eukaryotes)
- pyrimidine deoxyribonucleotides de novo biosynthesis I
- UDP-sugars interconversion
- superpathway of penicillin, cephalosporin and cephamycin biosynthesis
- deacetylcephalosporin C biosynthesis
- L-histidine biosynthesis
- L-threonine degradation II
- L-threonine degradation III (to methylglyoxal)
- superpathway of β-D-glucuronosides degradation
- superpathway of D-glucarate and D-galactarate degradation
- L-ascorbate biosynthesis IV
- glycerol degradation II
- aminopropanol phosphate biosynthesis II
- D-galacturonate degradation I
- superpathway of hexuronide and hexuronate degradation
- superpathway of L-threonine metabolism
- superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
- cichoriin interconversion
PlantCyc(6)
代谢反应
4 个相关的代谢反应过程信息。
Reactome(4)
- Metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA - Biological oxidations:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN - Phase II - Conjugation of compounds:
H2O + PNPB ⟶ BUT + PNP - Methylation:
H2O + SAH ⟶ Ade-Rib + HCYS
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- A A Amoscato, T Anthonymuthu, O Kapralov, L J Sparvero, I H Shrivastava, K Mikulska-Ruminska, V A Tyurin, A A Shvedova, Y Y Tyurina, I Bahar, S Wenzel, H Bayir, V E Kagan. Formation of protein adducts with Hydroperoxy-PE electrophilic cleavage products during ferroptosis.
Redox biology.
2023 May; 63(?):102758. doi:
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Photodiagnosis and photodynamic therapy.
2022 Jun; 38(?):102766. doi:
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Molecular and cellular biochemistry.
2021 Mar; 476(3):1467-1475. doi:
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Domestic animal endocrinology.
2021 01; 74(?):106572. doi:
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Future microbiology.
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Analytical biochemistry.
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Life sciences.
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PloS one.
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Journal of experimental botany.
2012 May; 63(8):2873-93. doi:
10.1093/jxb/err390. [PMID: 22323274] - Candida Vannini, Milena Marsoni, Carlo Cantara, Maria Concetta De Pinto, Vittoria Locato, Laura De Gara, Marcella Bracale. The soluble proteome of tobacco Bright Yellow-2 cells undergoing H₂O₂-induced programmed cell death.
Journal of experimental botany.
2012 May; 63(8):3137-55. doi:
10.1093/jxb/ers031. [PMID: 22355080] - Alison H Kingston-Smith, Teri E Davies, Joan Edwards, Alan Gay, Luis A J Mur. Evidence of a role for foliar salicylic acid in regulating the rate of post-ingestive protein breakdown in ruminants and contributing to landscape pollution.
Journal of experimental botany.
2012 May; 63(8):3243-55. doi:
10.1093/jxb/ers048. [PMID: 22378947] - K Sekine, T Takebe, Y Suzuki, A Kamiya, H Nakauchi, H Taniguchi. Highly efficient generation of definitive endoderm lineage from human induced pluripotent stem cells.
Transplantation proceedings.
2012 May; 44(4):1127-9. doi:
10.1016/j.transproceed.2012.03.001. [PMID: 22564643] - Shyamal K Das, Chandan Roy. The protective role of Aegle marmelos on aspirin-induced gastro-duodenal ulceration in albino rat model: a possible involvement of antioxidants.
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association.
2012 May; 18(3):188-94. doi:
10.4103/1319-3767.96452. [PMID: 22626798] - Takeo Aoki, Takeshi Suzuki, Haruo Hagiwara, Michio Kuwahara, Sei Sasaki, Kuniaki Takata, Toshiyuki Matsuzaki. Close association of aquaporin-2 internalization with caveolin-1.
Acta histochemica et cytochemica.
2012 Apr; 45(2):139-46. doi:
10.1267/ahc.12003. [PMID: 22685356] - Yen-Fei Lee, Ting-Wei Deng, Wei-Jane Chiu, Tsao-Yen Wei, Prathik Roy, Chih-Ching Huang. Visual detection of copper(II) ions in blood samples by controlling the leaching of protein-capped gold nanoparticles.
The Analyst.
2012 Apr; 137(8):1800-6. doi:
10.1039/c2an16270a. [PMID: 22378024] - Corina Verónica Sasso, María Aída Mattar de Anaya, Roberto C Davicino, Renzo Martino, Yolanda Casali, Blas Micalizzi. Neutralization of Pseudomonas aeruginosa enzymatic activity by antibodies elicited with proteins of Larrea divaricata Cav.
Immunopharmacology and immunotoxicology.
2012 Apr; 34(2):346-53. doi:
10.3109/08923973.2011.607827. [PMID: 22268619] - Ruohe Yin, Burkhard Messner, Theresa Faus-Kessler, Thomas Hoffmann, Wilfried Schwab, Mohammad-Reza Hajirezaei, Veronica von Saint Paul, Werner Heller, Anton R Schäffner. Feedback inhibition of the general phenylpropanoid and flavonol biosynthetic pathways upon a compromised flavonol-3-O-glycosylation.
Journal of experimental botany.
2012 Apr; 63(7):2465-78. doi:
10.1093/jxb/err416. [PMID: 22249996] - Michael R Paillasse, Nathalie Saffon, Heinz Gornitzka, Sandrine Silvente-Poirot, Marc Poirot, Philippe de Medina. Surprising unreactivity of cholesterol-5,6-epoxides towards nucleophiles.
Journal of lipid research.
2012 Apr; 53(4):718-25. doi:
10.1194/jlr.m023689. [PMID: 22285872] - Myung Hee Nam, Sun Mi Huh, Kyung Mi Kim, Woong June Park, Jong Bok Seo, Kun Cho, Dool Yi Kim, Beom Gi Kim, In Sun Yoon. Comparative proteomic analysis of early salt stress-responsive proteins in roots of SnRK2 transgenic rice.
Proteome science.
2012 Mar; 10(?):25. doi:
10.1186/1477-5956-10-25. [PMID: 22462395] - Sébastien Pyr Dit Ruys, Xuemin Wang, Ewan M Smith, Gaëtan Herinckx, Nusrat Hussain, Mark H Rider, Didier Vertommen, Christopher G Proud. Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase.
The Biochemical journal.
2012 Mar; 442(3):681-92. doi:
10.1042/bj20111530. [PMID: 22216903] - Kequan Deng, Youru Huang, Yufei Hua. Isolation of glycinin (11S) from lipid-reduced soybean flour: effect of processing conditions on yields and purity.
Molecules (Basel, Switzerland).
2012 Mar; 17(3):2968-79. doi:
10.3390/molecules17032968. [PMID: 22406901] - Pamela S Hair, Charlene G Echague, Reuben D Rohn, Neel K Krishna, Julius O Nyalwidhe, Kenji M Cunnion. Hyperglycemic conditions inhibit C3-mediated immunologic control of Staphylococcus aureus.
Journal of translational medicine.
2012 Mar; 10(?):35. doi:
10.1186/1479-5876-10-35. [PMID: 22390383] - Michael P Weekes, Robin Antrobus, Suzanne Talbot, Simon Hör, Nikol Simecek, Duncan L Smith, Stuart Bloor, Felix Randow, Paul J Lehner. Proteomic plasma membrane profiling reveals an essential role for gp96 in the cell surface expression of LDLR family members, including the LDL receptor and LRP6.
Journal of proteome research.
2012 Mar; 11(3):1475-84. doi:
10.1021/pr201135e. [PMID: 22292497] - Qiong Liu, Peilong Yang, Huiying Luo, Pengjun Shi, Huoqing Huang, Kun Meng, Bin Yao. A Novel endo-1,4-β-mannanase from Bispora antennata with good adaptation and stability over a broad pH range.
Applied biochemistry and biotechnology.
2012 Mar; 166(6):1442-53. doi:
10.1007/s12010-011-9537-z. [PMID: 22258646] - Hiroyuki Wadahama, Kensuke Iwasaki, Motonori Matsusaki, Keito Nishizawa, Masao Ishimoto, Fumio Arisaka, Kyoko Takagi, Reiko Urade. Accumulation of β-conglycinin in soybean cotyledon through the formation of disulfide bonds between α'- and α-subunits.
Plant physiology.
2012 Mar; 158(3):1395-405. doi:
10.1104/pp.111.189621. [PMID: 22218927] - G Júnior Nardi, M G Ribeiro, A M Jorge, J Megid, L M P Silva. Serological profile of buffalo (Bubalus bubalis) female calves vaccinated with standard Brucella abortus strain 19 vaccine using rose bengal, 2-mercaptoethanol and complement fixation tests.
Biologicals : journal of the International Association of Biological Standardization.
2012 Mar; 40(2):158-61. doi:
10.1016/j.biologicals.2011.09.016. [PMID: 22284623] - Christian Mueller, Qiushi Tang, Alisha Gruntman, Keith Blomenkamp, Jeffery Teckman, Lina Song, Phillip D Zamore, Terence R Flotte. Sustained miRNA-mediated knockdown of mutant AAT with simultaneous augmentation of wild-type AAT has minimal effect on global liver miRNA profiles.
Molecular therapy : the journal of the American Society of Gene Therapy.
2012 03; 20(3):590-600. doi:
10.1038/mt.2011.292. [PMID: 22252449] - Anne Honsel, Mikiko Kojima, Richard Haas, Wolfgang Frank, Hitoshi Sakakibara, Cornelia Herschbach, Heinz Rennenberg. Sulphur limitation and early sulphur deficiency responses in poplar: significance of gene expression, metabolites, and plant hormones.
Journal of experimental botany.
2012 Mar; 63(5):1873-93. doi:
10.1093/jxb/err365. [PMID: 22162873] - Se-Hwan Joo, Tae-Wuk Kim, Seung-Hyun Son, Woo Sung Lee, Takao Yokota, Seong-Ki Kim. Biosynthesis of a cholesterol-derived brassinosteroid, 28-norcastasterone, in Arabidopsis thaliana.
Journal of experimental botany.
2012 Mar; 63(5):1823-33. doi:
10.1093/jxb/err354. [PMID: 22170941] - Joao Helder Frederico de Faria Naves, Lais M Rezende, Gabriel C Ramos, Pollyanna M Soares, Tatiane C F Tavares, Andre M S França, Saira M N Neves, Natascha A M Silva, Anna M C Lima-Ribeiro. Interference in diagnostic tests for brucellosis in cattle recently vaccinated against leptospirosis.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.
2012 Mar; 24(2):283-7. doi:
10.1177/1040638711432004. [PMID: 22379045] - Masanori Izumi, Honami Tsunoda, Yuji Suzuki, Amane Makino, Hiroyuki Ishida. RBCS1A and RBCS3B, two major members within the Arabidopsis RBCS multigene family, function to yield sufficient Rubisco content for leaf photosynthetic capacity.
Journal of experimental botany.
2012 Mar; 63(5):2159-70. doi:
10.1093/jxb/err434. [PMID: 22223809] - Anahita Sanaei Dashti, Abdollah Karimi, Vadood Javad, Farideh Shiva, Fatemeh Fallah, Mohammad Reza Alaei, Goli Angoti, Zahra Pournasiri. ELISA Cut-off Point for the Diagnosis of Human Brucellosis; a Comparison with Serum Agglutination Test.
Iranian journal of medical sciences.
2012 Mar; 37(1):9-14. doi:
NULL. [PMID: 23115425] - Ladislav Dokládal, Michal Oboril, Karel Stejskal, Zbynek Zdráhal, Nikola Ptácková, Radka Chaloupková, Jirí Damborsky, Tomás Kasparovsky, Sylvain Jeandroz, Markéta Zd'árská, Jan Lochman. Physiological and proteomic approaches to evaluate the role of sterol binding in elicitin-induced resistance.
Journal of experimental botany.
2012 Mar; 63(5):2203-15. doi:
10.1093/jxb/err427. [PMID: 22223811] - Carlos Salas, Orlando J Rojas, Lucian A Lucia, Martin A Hubbe, Jan Genzer. Adsorption of glycinin and β-conglycinin on silica and cellulose: surface interactions as a function of denaturation, pH, and electrolytes.
Biomacromolecules.
2012 Feb; 13(2):387-96. doi:
10.1021/bm2014153. [PMID: 22229657] - Clement C Cheung, Melissa A Cadnapaphornchai, Sayali A Ranadive, Stephen E Gitelman, Stephen M Rosenthal. Persistent elevation of urine aquaporin-2 during water loading in a child with nephrogenic syndrome of inappropriate antidiuresis (NSIAD) caused by a R137L mutation in the V2 vasopressin receptor.
International journal of pediatric endocrinology.
2012 Feb; 2012(1):3. doi:
10.1186/1687-9856-2012-3. [PMID: 22325688] - Chenqi Hu, Dejan Nikolic, Aimee L Eggler, Andrew D Mesecar, Richard B van Breemen. Screening for natural chemoprevention agents that modify human Keap1.
Analytical biochemistry.
2012 Feb; 421(1):108-14. doi:
10.1016/j.ab.2011.10.028. [PMID: 22074792] - Yusuke Sugiyama, Misugi Uraji, Megumi Watanabe-Sugimoto, Eiji Okuma, Shintaro Munemasa, Yasuaki Shimoishi, Yoshimasa Nakamura, Izumi C Mori, Sumio Iwai, Yoshiyuki Murata. FIA functions as an early signal component of abscisic acid signal cascade in Vicia faba guard cells.
Journal of experimental botany.
2012 Feb; 63(3):1357-65. doi:
10.1093/jxb/err369. [PMID: 22131163] - Nikolay Kovalev, Judit Pogany, Peter D Nagy. A Co-Opted DEAD-Box RNA helicase enhances tombusvirus plus-strand synthesis.
PLoS pathogens.
2012 Feb; 8(2):e1002537. doi:
10.1371/journal.ppat.1002537. [PMID: 22359508] - T Subramani, K S Chandrashekharaiah, N Ramachandra Swamy, K R Siddalinga Murthy. Purification and characterization of carboxylesterase from the seeds of Jatropha curcas.
The protein journal.
2012 Feb; 31(2):120-8. doi:
10.1007/s10930-011-9380-7. [PMID: 22173274] - Kyu-Sang Park, Andreas Wiederkehr, Claes B Wollheim. Defective mitochondrial function and motility due to mitofusin 1 overexpression in insulin secreting cells.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.
2012 Feb; 16(1):71-7. doi:
10.4196/kjpp.2012.16.1.71. [PMID: 22416223] - Mohammad A Hossain, Sereyrath Ngeth, Teddy Chan, Michael N Oda, Gordon A Francis. Lipid-bound apolipoproteins in tyrosyl radical-oxidized HDL stabilize ABCA1 like lipid-free apolipoprotein A-I.
BMC biochemistry.
2012 Jan; 13(?):1. doi:
10.1186/1471-2091-13-1. [PMID: 22248050] - Yoon-Ok Jang, Xianglan Quan, Ranjan Das, Shanhua Xu, Choon-Hee Chung, Chan Mug Ahn, Soon-Koo Baik, In Deok Kong, Kyu-Sang Park, Moon Young Kim. High-dose clevudine impairs mitochondrial function and glucose-stimulated insulin secretion in INS-1E cells.
BMC gastroenterology.
2012 Jan; 12(?):4. doi:
10.1186/1471-230x-12-4. [PMID: 22230186] - Andrea D Olmstead, Wolfgang Knecht, Ina Lazarov, Surjit B Dixit, François Jean. Human subtilase SKI-1/S1P is a master regulator of the HCV Lifecycle and a potential host cell target for developing indirect-acting antiviral agents.
PLoS pathogens.
2012 Jan; 8(1):e1002468. doi:
10.1371/journal.ppat.1002468. [PMID: 22241994] - Matthias Dorn, Marcel Jurk, Peter Schmieder. Blue news update: BODIPY-GTP binds to the blue-light receptor YtvA while GTP does not.
PloS one.
2012; 7(1):e29201. doi:
10.1371/journal.pone.0029201. [PMID: 22247770] - Sayuri Suzuki, Hirotaka Fukasawa, Taro Misaki, Akashi Togawa, Naro Ohashi, Kyoko Kitagawa, Yojiro Kotake, Ning Liu, Hiroyuki Niida, Keiko Nakayama, Keiichi I Nakayama, Tatsuo Yamamoto, Masatoshi Kitagawa. The amelioration of renal damage in Skp2-deficient mice canceled by p27 Kip1 deficiency in Skp2-/- p27-/- mice.
PloS one.
2012; 7(4):e36249. doi:
10.1371/journal.pone.0036249. [PMID: 22558406] - Rodrigo Herrera-Molina, Renato Frischknecht, Horacio Maldonado, Constanze I Seidenbecher, Eckart D Gundelfinger, Claudio Hetz, María de la Luz Aylwin, Pascal Schneider, Andrew F G Quest, Lisette Leyton. Astrocytic αVβ3 integrin inhibits neurite outgrowth and promotes retraction of neuronal processes by clustering Thy-1.
PloS one.
2012; 7(3):e34295. doi:
10.1371/journal.pone.0034295. [PMID: 22479590] - Weisong Zhou, Dustin R Dowell, Matthew M Huckabee, Dawn C Newcomb, Madison G Boswell, Kasia Goleniewska, Matthew T Lotz, Shinji Toki, Huiyong Yin, Songyi Yao, Chandramohan Natarajan, Pingsheng Wu, Subramaniam Sriram, Richard M Breyer, Garret A Fitzgerald, R Stokes Peebles. Prostaglandin I2 signaling drives Th17 differentiation and exacerbates experimental autoimmune encephalomyelitis.
PloS one.
2012; 7(5):e33518. doi:
10.1371/journal.pone.0033518. [PMID: 22590492] - Panjamaporn Sangwung, Todd M Greco, Yanzhuang Wang, Harry Ischiropoulos, William C Sessa, Yasuko Iwakiri. Proteomic identification of S-nitrosylated Golgi proteins: new insights into endothelial cell regulation by eNOS-derived NO.
PloS one.
2012; 7(2):e31564. doi:
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