Mitomycin (BioDeep_00000003878)

 

Secondary id: BioDeep_00001867683

human metabolite blood metabolite Chemicals and Drugs Antibiotics


代谢物信息卡片


[(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.0²,⁷.0⁴,⁶]trideca-1(9),11-dien-8-yl]methyl carbamate

化学式: C15H18N4O5 (334.1277)
中文名称: 丝裂霉素C
谱图信息: 最多检出来源 Homo sapiens(blood) 69.74%

分子结构信息

SMILES: CC1=C(C(=O)C2=C(C1=O)N1C[C@H]3[C@@H]([C@@]1([C@@H]2COC(=O)N)OC)N3)N
InChI: InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1

描述信息

Mitomycin is only found in individuals that have used or taken this drug. It is an antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional alkylating agents causing cross-linking of DNA and inhibition of DNA synthesis. [PubChem]Mitomycin is activated in vivo to a bifunctional and trifunctional alkylating agent. Binding to DNA leads to cross-linking and inhibition of DNA synthesis and function. Mitomycin is cell cycle phase-nonspecific.
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01D - Cytotoxic antibiotics and related substances
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C259 - Antineoplastic Antibiotic
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D003432 - Cross-Linking Reagents
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent
D000970 - Antineoplastic Agents > D000903 - Antibiotics, Antineoplastic > D008937 - Mitomycins
D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors
D009676 - Noxae > D000477 - Alkylating Agents

同义名列表

17 个代谢物同义名

[(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.0²,⁷.0⁴,⁶]trideca-1(9),11-dien-8-yl]methyl carbamate; 7-Amino-9alpha-methoxymitosane; 7-Amino-9a-methoxymitosane; 7-Amino-9α-methoxymitosane; Mitomycin C; Mitomycin-C; Mitamycin; Mitocin C; Ametycine; Mitocin-C; Mitomycin; Mutamycin; Muamycin; MitocinC; Mit-C; MMC; Mitomycin



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

6 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ABCB1, ALB, ANXA5, BRCA1, FANCA, FANCC, FANCG, NQO1, TP53
Peripheral membrane protein 1 ANXA5
Endoplasmic reticulum membrane 1 CD4
Nucleus 11 ALB, BRCA1, FANCA, FANCC, FANCD2, FANCG, NQO1, PARP1, PCNA, TP53, ZNF77
cytosol 9 ALB, ANXA5, FANCA, FANCC, FANCD2, FANCG, NQO1, PARP1, TP53
dendrite 1 NQO1
nuclear body 4 BRCA1, FANCD2, PARP1, PCNA
centrosome 3 ALB, PCNA, TP53
nucleoplasm 8 BRCA1, FANCA, FANCC, FANCD2, FANCG, PARP1, PCNA, TP53
Cell membrane 4 ABCB1, CD4, CD8A, TNF
Multi-pass membrane protein 1 ABCB1
Synapse 1 NQO1
cell surface 2 ABCB1, TNF
Golgi apparatus 1 ALB
lysosomal membrane 1 EGF
neuronal cell body 2 NQO1, TNF
sarcolemma 1 ANXA5
Cytoplasm, cytosol 2 NQO1, PARP1
plasma membrane 8 ABCB1, BRCA1, CD4, CD8A, EGF, FANCG, IFNLR1, TNF
Membrane 8 ABCB1, ANXA5, BRCA1, EGF, IFNLR1, NQO1, PARP1, TP53
apical plasma membrane 1 ABCB1
extracellular exosome 5 ABCB1, ALB, ANXA5, EGF, PCNA
endoplasmic reticulum 2 ALB, TP53
extracellular space 4 ALB, EGF, IL2, TNF
mitochondrion 3 FANCG, PARP1, TP53
protein-containing complex 4 ALB, BRCA1, PARP1, TP53
Single-pass type I membrane protein 3 CD4, CD8A, IFNLR1
Secreted 2 ALB, IL2
extracellular region 6 ALB, ANXA5, CD8A, EGF, IL2, TNF
[Isoform 2]: Secreted 1 CD8A
Mitochondrion matrix 1 TP53
mitochondrial matrix 1 TP53
anchoring junction 1 ALB
transcription regulator complex 2 PARP1, TP53
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
external side of plasma membrane 4 ANXA5, CD4, CD8A, TNF
nucleolus 4 FANCD2, FANCG, PARP1, TP53
Early endosome 1 CD4
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Apical cell membrane 1 ABCB1
Membrane raft 2 CD4, TNF
Cytoplasm, cytoskeleton 1 TP53
focal adhesion 1 ANXA5
Nucleus, PML body 1 TP53
PML body 1 TP53
collagen-containing extracellular matrix 1 ANXA5
receptor complex 1 CD8A
Zymogen granule membrane 1 ANXA5
ciliary basal body 1 ALB
chromatin 7 FANCA, FANCC, FANCD2, FANCG, PARP1, PCNA, TP53
phagocytic cup 1 TNF
Chromosome 2 BRCA1, PARP1
centriole 1 ALB
[Isoform 5]: Cytoplasm 1 BRCA1
Nucleus, nucleolus 1 PARP1
spindle pole 1 ALB
nuclear replication fork 2 PARP1, PCNA
chromosome, telomeric region 2 PARP1, PCNA
blood microparticle 1 ALB
site of double-strand break 2 PARP1, TP53
nuclear envelope 1 PARP1
Fanconi anaemia nuclear complex 3 FANCA, FANCC, FANCG
lateral element 1 BRCA1
germ cell nucleus 1 TP53
replication fork 2 PCNA, TP53
ubiquitin ligase complex 1 BRCA1
plasma membrane raft 1 CD8A
endoplasmic reticulum lumen 2 ALB, CD4
nuclear matrix 1 TP53
transcription repressor complex 1 TP53
male germ cell nucleus 2 BRCA1, PCNA
platelet alpha granule lumen 2 ALB, EGF
XY body 1 BRCA1
vesicle membrane 1 ANXA5
nuclear lamina 1 PCNA
clathrin-coated endocytic vesicle membrane 2 CD4, EGF
ribonucleoprotein complex 1 BRCA1
[Isoform 1]: Nucleus 1 TP53
protein-DNA complex 1 PARP1
external side of apical plasma membrane 1 ABCB1
[Isoform 1]: Cell membrane 1 CD8A
intracellular non-membrane-bounded organelle 1 BRCA1
condensed chromosome 1 FANCD2
DNA repair complex 2 BRCA1, FANCD2
BRCA1-C complex 1 BRCA1
site of DNA damage 1 PARP1
cyclin-dependent protein kinase holoenzyme complex 1 PCNA
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 2 CD4, CD8A
endothelial microparticle 1 ANXA5
[Poly [ADP-ribose] polymerase 1, processed N-terminus]: Chromosome 1 PARP1
[Poly [ADP-ribose] polymerase 1, processed C-terminus]: Cytoplasm 1 PARP1
PCNA complex 1 PCNA
PCNA-p21 complex 1 PCNA
replisome 1 PCNA
BRCA1-A complex 1 BRCA1
BRCA1-B complex 1 BRCA1
BRCA1-BARD1 complex 1 BRCA1
gamma-tubulin ring complex 1 BRCA1
nuclear ubiquitin ligase complex 1 BRCA1
ciliary transition fiber 1 ALB
interleukin-28 receptor complex 1 IFNLR1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Ya-Mei Wu, Xue-Qiong Yang, Ya-Bin Yang, Le Cai, Fei-Fei He, Zhong-Tao Ding. The antifungal metabolites from coculture of Aspergillus fumigatus and Alternaria alternata associated with Coffea arabica. Natural product research. 2024 Feb; 38(5):753-758. doi: 10.1080/14786419.2023.2196722. [PMID: 37021795]
  • Jingya Wang, Jiangli Xu, Shuhui Yang, Liu He, Wenhuai Xu, Yan'e Liu, Baoshan Cao, Siwang Yu. SN-38, an active metabolite of irinotecan, inhibits transcription of nuclear factor erythroid 2-related factor 2 and enhances drug sensitivity of colorectal cancer cells. Molecular carcinogenesis. 2024 Jan; ?(?):. doi: 10.1002/mc.23685. [PMID: 38270247]
  • Qian Wang. Five cuprotosis-related lncRNA signatures for prognosis prediction in acute myeloid leukaemia. Hematology (Amsterdam, Netherlands). 2023 Dec; 28(1):2231737. doi: 10.1080/16078454.2023.2231737. [PMID: 37417765]
  • Piotr Jarocki, Elwira Komoń-Janczara, Agata Młodzińska, Jan Sadurski, Kinga Kołodzińska, Łukasz Łaczmański, Jacek Panek, Magdalena Frąc. Occurrence and genetic diversity of prophage sequences identified in the genomes of L. casei group bacteria. Scientific reports. 2023 05; 13(1):8603. doi: 10.1038/s41598-023-35823-z. [PMID: 37237003]
  • Deniz Yuzbasioglu, Ummugulsum Kubra Dilek, Esra Erikel, Fatma Unal. Antigenotoxic effect of hyperoside against Mitomycin C and hydrogen peroxide-induced genotoxic damage on human lymphocytes. Toxicology in vitro : an international journal published in association with BIBRA. 2023 May; 90(?):105604. doi: 10.1016/j.tiv.2023.105604. [PMID: 37137419]
  • Feng Yang, Eduardo F C Scopel, Hao Li, Liu-Liu Sun, Nora Kawar, Yong-Bing Cao, Yuan-Ying Jiang, Judith Berman. Antifungal Tolerance and Resistance Emerge at Distinct Drug Concentrations and Rely upon Different Aneuploid Chromosomes. mBio. 2023 04; 14(2):e0022723. doi: 10.1128/mbio.00227-23. [PMID: 36877011]
  • Weihua Chen, Mingyue Tan, Chao Yu, Guoqiang Liao, Dehui Kong, Jie Bai, Bo Yang, Hua Gong. ARHGAP6 inhibits bladder cancer cell viability, migration, and invasion via β-catenin signaling and enhances mitomycin C sensitivity. Human cell. 2023 Mar; 36(2):786-797. doi: 10.1007/s13577-023-00860-3. [PMID: 36715867]
  • Margarita Dormousoglou, Vasiliki Boti, Dimitra Hela, Dimitris Vlastos, Maria Antonopoulou, Christos Chondrogiannis, Yiola Petropoulou, Stefanos Dailianis. Beneficial properties of Drimia numidica leaf methanolic extract against the cytogenotoxic effects of mitomycin C on human lymphocytes. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 Mar; 173(?):113626. doi: 10.1016/j.fct.2023.113626. [PMID: 36682415]
  • Anastasiya Vinokurtseva, James J Armstrong, Hong Liu, Cindy M L Hutnik. Differential effects of acetylsalicylic acid and mitomycin C on cytokine-induced Tenon's capsule myofibroblast transdifferentiation and activity: Implications for glaucoma surgery. Experimental eye research. 2022 12; 225(?):109284. doi: 10.1016/j.exer.2022.109284. [PMID: 36273575]
  • Michael Mimouni, Dean Ouano. Initial outcomes of mitomycin intravascular chemoembolization (MICE) for corneal neovascularization. International ophthalmology. 2022 Aug; 42(8):2407-2416. doi: 10.1007/s10792-022-02240-6. [PMID: 35099664]
  • Geoffrey H Rosen, Ankita Nallani, Catherine Muzzey, Katie S Murray. Antegrade Instillation of UGN-101 (Mitomycin for Pyelocalyceal Solution) for Low-Grade Upper Tract Urothelial Carcinoma: Initial Clinical Experience. The Journal of urology. 2022 06; 207(6):1302-1311. doi: 10.1097/ju.0000000000002454. [PMID: 35130080]
  • Swati D G Rayasam, Max T Aung, Courtney Cooper, Carol Kwiatkowski, Dori R Germolec, Andrew A Rooney, Vickie R Walker, Chanese Forte, Tracey J Woodruff, Nicholas Chartres. Identifying environmental factors that influence immune response to SARS-CoV-2: Systematic evidence map protocol. Environment international. 2022 06; 164(?):107230. doi: 10.1016/j.envint.2022.107230. [PMID: 35447423]
  • Surena F Matin, Phillip M Pierorazio, Nir Kleinmann, John L Gore, Ahmad Shabsigh, Brian Hu, Karim Chamie, Guilherme Godoy, Scott G Hubosky, Marcelino Rivera, Michael O'Donnell, Marcus Quek, Jay D Raman, John J Knoedler, Douglas Scherr, Christopher Weight, Alon Weizer, Michael Woods, Hristos Kaimakliotis, Angela B Smith, Jennifer Linehan, Jonathan Coleman, Mitchell R Humphreys, Raymond Pak, David Lifshitz, Michael Verni, Ifat Klein, Marina Konorty, Dalit Strauss-Ayali, Gil Hakim, Elyse Seltzer, Mark Schoenberg, Seth P Lerner. Durability of Response to Primary Chemoablation of Low-Grade Upper Tract Urothelial Carcinoma Using UGN-101, a Mitomycin-Containing Reverse Thermal Gel: OLYMPUS Trial Final Report. The Journal of urology. 2022 Apr; 207(4):779-788. doi: 10.1097/ju.0000000000002350. [PMID: 34915741]
  • P Leon, F Saint, F Audenet, M Roumiguié, Y Allory, Y Loriot, A Masson-Lecomte, B Pradère, T Seisen, O Traxer, E Xylinas, M Roupret, Y Neuzillet. [Guidelines from the cancer committee of the French Association of Urology (CC-AFU) for adequate intravesical instillations of Mitomycin C, Epirubicin, and BCG for non-muscle invasive bladder cancer]. Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie. 2022 Apr; 32(5):299-311. doi: 10.1016/j.purol.2022.01.004. [PMID: 35151545]
  • P Rollin, E Xylinas, C Lanz, F Audenet, S Brunelle, E Compérat, N Houédé, S Larré, A Masson-Lecomte, G Pignot, M Roumiguié, A Méjean, M Rouprêt, Y Neuzillet. [Intravesical adjuvant regimen of epitubicin for intermediate risk NMIBC: Feasability study from CC-AFU vessie]. Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie. 2022 Apr; 32(5):326-331. doi: 10.1016/j.purol.2021.12.008. [PMID: 35151544]
  • Aleksandra Marković, Jovana Tubić Vukajlović, Darko Grujičić, Marina Radović Jakovljević, Milan Stanković, Katarina Djordjević, Ninoslav Djelić, Milena Radaković, Olivera Milošević-Djordjević. Methanol extracts of Teucrium arduini L. and Teucrium flavum L. induce protective effect against mitomycin C in human lymphocytes in vitro. Drug and chemical toxicology. 2022 Mar; 45(2):940-946. doi: 10.1080/01480545.2020.1802477. [PMID: 32752893]
  • Naheema S Gordon, Laura A Baxter, Anshita Goel, Roland Arnold, Baljit Kaur, Wenyu Liu, Sarah J Pirrie, Syed Hussain, Richard Viney, Daniel Ford, Anjali Zarkar, Mary A Wood, Timur Mitin, Reid F Thompson, Nicholas D James, Douglas G Ward, Richard T Bryan. Urine DNA for monitoring chemoradiotherapy response in muscle-invasive bladder cancer: a pilot study. BJU international. 2022 01; 129(1):32-34. doi: 10.1111/bju.15589. [PMID: 34491610]
  • Marina Martinez-Garcia, Charles I White, F Chris H Franklin, Eugenio Sanchez-Moran. The Role of Topoisomerase II in DNA Repair and Recombination in Arabidopsis thaliana. International journal of molecular sciences. 2021 Dec; 22(23):. doi: 10.3390/ijms222313115. [PMID: 34884922]
  • F Edward Boas, Nancy E Kemeny, Constantinos T Sofocleous, Randy Yeh, Vanessa R Thompson, Meier Hsu, Chaya S Moskowitz, Etay Ziv, Hooman Yarmohammadi, Achiude Bendet, Stephen B Solomon. Bronchial or Pulmonary Artery Chemoembolization for Unresectable and Unablatable Lung Metastases: A Phase I Clinical Trial. Radiology. 2021 11; 301(2):474-484. doi: 10.1148/radiol.2021210213. [PMID: 34463550]
  • Serpil Yazgan, Ishak Ozel Tekin, Nusret Akpolat, Ozhan Koc. Novel Bacterial Cellulose Membrane to Reduce Fibrosis Following Trabeculectomy. Journal of glaucoma. 2021 11; 30(11):1001-1010. doi: 10.1097/ijg.0000000000001907. [PMID: 34224487]
  • Karl H Pang, Christopher R Chapple, Robin Chatters, Alison P Downey, Christopher K Harding, Daniel Hind, Nick Watkin, Nadir I Osman. A Systematic Review and Meta-analysis of Adjuncts to Minimally Invasive Treatment of Urethral Stricture in Men. European urology. 2021 10; 80(4):467-479. doi: 10.1016/j.eururo.2021.06.022. [PMID: 34275660]
  • Patricia B Lodato. The effect of two ribonucleases on the production of Shiga toxin and stx-bearing bacteriophages in Enterohaemorrhagic Escherichia coli. Scientific reports. 2021 09; 11(1):18372. doi: 10.1038/s41598-021-97736-z. [PMID: 34526533]
  • Leen Naji, Brittany Dennis, Rebecca L Morgan, Nitika Sanger, Andrew Worster, James Paul, Lehana Thabane, Zainab Samaan. Investigating and addressing the immediate and long-term consequences of the COVID-19 pandemic on patients with substance use disorders: a scoping review and evidence map protocol. BMJ open. 2021 09; 11(9):e045946. doi: 10.1136/bmjopen-2020-045946. [PMID: 34493506]
  • Rahul Dwivedi, Tobi Somerville, Robert Cheeseman, Clare Rogers, Mark Batterbury, Anshoo Choudhary. Deep sclerectomy and trabeculectomy augmented with Mitomycin C: 2-year post-operative outcomes. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. 2021 Jul; 259(7):1965-1974. doi: 10.1007/s00417-021-05144-w. [PMID: 33683432]
  • Jason M Farrow, Sean Q Kern, Gustavo M Gryzinski, Chandru P Sundaram. Nephron-sparing management of upper tract urothelial carcinoma. Investigative and clinical urology. 2021 07; 62(4):389-398. doi: 10.4111/icu.20210113. [PMID: 34190434]
  • Taygun Timocin, Mehmet Arslan, Hasan Basri Ila. Evaluation of in vitro and in vivo genotoxic and antigenotoxic effects of Rhus coriaria. Drug and chemical toxicology. 2021 Jul; 44(4):409-417. doi: 10.1080/01480545.2019.1593433. [PMID: 30945575]
  • Ahmad Shabsigh, Nir Kleinmann, Angela B Smith, Douglas Scherr, Elyse Seltzer, Mark Schoenberg, Seth P Lerner. Pharmacokinetics of UGN-101, a mitomycin-containing reverse thermal gel instilled via retrograde catheter for the treatment of low-grade upper tract urothelial carcinoma. Cancer chemotherapy and pharmacology. 2021 06; 87(6):799-805. doi: 10.1007/s00280-021-04246-w. [PMID: 33677615]
  • A Taibi, M-L Perrin, J Albouys, J Jacques, C Yardin, S Durand-Fontanier, S M Bardet. 10 ns PEFs induce a histological response linked to cell death and cytotoxic T-lymphocytes in an immunocompetent mouse model of peritoneal metastasis. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 2021 Jun; 23(6):1220-1237. doi: 10.1007/s12094-020-02525-1. [PMID: 33677709]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Yeong-Chin Jou, Shou-Chieh Wang, Yuan-Chang Dia, Shou-Tsung Wang, Min-Hua Yu, Hsin-Yi Yang, Lei-Chin Chen, Cheng-Huang Shen, Yi-Wen Liu. Anti-Cancer Effects and Tumor Marker Role of Glutathione S-Transferase Mu 5 in Human Bladder Cancer. International journal of molecular sciences. 2021 Mar; 22(6):. doi: 10.3390/ijms22063056. [PMID: 33802702]
  • Francesco Pierconti, Maurizio Martini, Vincenzo Fiorentino, Tonia Cenci, Sara Capodimonti, Patrizia Straccia, Emilio Sacco, Dario Pugliese, Luca Cindolo, Luigi Maria Larocca, Pier Francesco Bassi. The combination cytology/epichek test in non muscle invasive bladder carcinoma follow-up: Effective tool or useless expence?. Urologic oncology. 2021 02; 39(2):131.e17-131.e21. doi: 10.1016/j.urolonc.2020.06.018. [PMID: 32773233]
  • Ronald M Sanchez-Avila, Edmar E Uribe-Badillo, Javier Fernández-Vega Sanz, Francisco Muruzabal, Nancy Jurado, Belén Alfonso-Bartolozzi, Jose F Alfonso, Begoña Baamonde, Eduardo Anitua, Jesus Merayo-Lloves. Plasma rich in growth factors versus Mitomycin C in photorefractive keratectomy. Medicine. 2021 Jan; 100(3):e24139. doi: 10.1097/md.0000000000024139. [PMID: 33546027]
  • Aïcha Sassi, Jihed Boubaker, Amira Loussaief, Khaoula Jomaa, Kamel Ghedira, Leila Chekir-Ghedira. Protective Effect of Chrysin, a Dietary Flavone against Genotoxic and Oxidative Damage Induced by Mitomycin C in Balb/C Mice. Nutrition and cancer. 2021; 73(2):329-338. doi: 10.1080/01635581.2020.1749289. [PMID: 32270711]
  • Jennifer Linehan, Mark Schoenberg, Elyse Seltzer, Kim Thacker, Angela B Smith. Complications Associated With Ureteroscopic Management of Upper Tract Urothelial Carcinoma. Urology. 2021 01; 147(?):87-95. doi: 10.1016/j.urology.2020.09.036. [PMID: 33031842]
  • Yu-Ching Wen, Liang-Ming Lee, Yung-Wei Lin, Syuan-Hao Syu, Ke-Hsun Lin, Yen-Chun Fan, Hsin-Lun Lee, Benjamin Chung Howe Lai, Hung-Jen Shih. Loco-regional deep hyperthermia combined with intravesical Mitomycin instillation reduces the recurrence of non-muscle invasive papillary bladder cancer. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2021; 38(1):1627-1632. doi: 10.1080/02656736.2021.2001582. [PMID: 34775895]
  • Camillo Porta, Patrizia Giannatempo, Mimma Rizzo, Giuseppe Lucarelli, Pasquale Ditonno, Michele Battaglia. An evaluation of UGN-101, a sustained-release hydrogel polymer-based formulation containing mitomycin-C, for the treatment of upper urothelial carcinomas. Expert opinion on pharmacotherapy. 2020 Dec; 21(18):2199-2204. doi: 10.1080/14656566.2020.1805433. [PMID: 32870051]
  • Aziz Gulamhusein, Pedro Silva, David Cullen, Maxine Tran, Faiz Mumtaz, Prasad Patki, Ravi Barod, Axel Bex. Safety and feasibility of early single-dose mitomycin C bladder instillation after robot-assisted radical nephroureterectomy. BJU international. 2020 12; 126(6):739-744. doi: 10.1111/bju.15162. [PMID: 32638490]
  • Fangshi Xu, Yibing Guan, Li Xue, Xi Lan, Ke Gao, Tie Chong. Efficacy and safety of injection treatment after internal urethrotomy on the prevention of stricture recurrence: a network meta-analysis. Minerva chirurgica. 2020 12; 75(6):471-473. doi: 10.23736/s0026-4733.20.08301-7. [PMID: 32773738]
  • Alberto A Gabizon, Esther Tahover, Talia Golan, Ravit Geva, Ruth Perets, Yasmine Amitay, Hilary Shmeeda, Patricia Ohana. Pharmacokinetics of mitomycin-c lipidic prodrug entrapped in liposomes and clinical correlations in metastatic colorectal cancer patients. Investigational new drugs. 2020 10; 38(5):1411-1420. doi: 10.1007/s10637-020-00897-3. [PMID: 31955309]
  • Dan-Dan Xu, Men Ding, Pan Tong, Yan-Yun Chong, Wei-Yu Gu, Yang Li, Xin-Jiang Fang, Ning Li. Synergistic effects of low‑dose chemotherapy and T cells in renal cell carcinoma. Oncology reports. 2020 09; 44(3):897-908. doi: 10.3892/or.2020.7679. [PMID: 32705278]
  • Yuval Freifeld, Rashed Ghandour, Nirmish Singla, Solomon Woldu, Aditya Bagrodia, Yair Lotan, Leonid M Rapoport, Magomet Gazimiev, Karen Delafuente, Rohan Kulangara, Haley Robyak, Firas G Petros, Jay D Raman, Surena F Matin, Vitaly Margulis. Intraoperative prophylactic intravesical chemotherapy to reduce bladder recurrence following radical nephroureterectomy. Urologic oncology. 2020 09; 38(9):737.e11-737.e16. doi: 10.1016/j.urolonc.2020.05.002. [PMID: 32641241]
  • Rongxin Li, Ye Li, Jun Song, Ke Gao, Kangning Chen, Xiaogang Yang, Yongqiang Ding, Xinlong Ma, Yang Wang, Weipeng Li, Yanan Wang, Zhiping Wang, Zhilong Dong. Intravesical gemcitabine versus mitomycin for non-muscle invasive bladder cancer: a systematic review and meta-analysis of randomized controlled trial. BMC urology. 2020 Jul; 20(1):97. doi: 10.1186/s12894-020-00610-9. [PMID: 32660456]
  • Nir Kleinmann, Surena F Matin, Phillip M Pierorazio, John L Gore, Ahmad Shabsigh, Brian Hu, Karim Chamie, Guilherme Godoy, Scott Hubosky, Marcelino Rivera, Michael O'Donnell, Marcus Quek, Jay D Raman, John J Knoedler, Douglas Scherr, Joshua Stern, Christopher Weight, Alon Weizer, Michael Woods, Hristos Kaimakliotis, Angela B Smith, Jennifer Linehan, Jonathan Coleman, Mitchell R Humphreys, Raymond Pak, David Lifshitz, Michael Verni, Mehrad Adibi, Mahul B Amin, Elyse Seltzer, Ifat Klein, Marina Konorty, Dalit Strauss-Ayali, Gil Hakim, Mark Schoenberg, Seth P Lerner. Primary chemoablation of low-grade upper tract urothelial carcinoma using UGN-101, a mitomycin-containing reverse thermal gel (OLYMPUS): an open-label, single-arm, phase 3 trial. The Lancet. Oncology. 2020 06; 21(6):776-785. doi: 10.1016/s1470-2045(20)30147-9. [PMID: 32631491]
  • Dario Baratti, Paolo Sammartino, Shigeki Kusamura, Marcello Deraco, Luca Ansaloni, Salvatore Asero, Gianluca Baiocchi, Pietro Bagnoli, Davide Cavaliere, Massimo Framarini, Roberto Cirocchi, Federico Coccolini, Franco Decian, Paolo Delrio, Cinzia Sassaroli, Michele De Simone, Manuela Robella, Marco Vaira, Andrea Di Giorgio, Anna Fagotti, Domenica Lorusso, Orietta Federici, Giammaria Fiorentini, Massimiliano Fambrini, Stefano Scaringi, Alfredo Garofalo, Mario Valle, Roberta Gelmini, Francesca Cabry, Nicola Cautero, Lorena Sorrentino, Luigina Graziosi, Marcello Guaglio, Matteo Montenovo, Valentina Bartolini, Piero Vincenzo Lippolis, Antonio Macrì, Enrico Maria Pasqual, Francesco Roviello, Daniele Marrelli, Elena Orsenigo, Antonio Sommariva. Past, present and future of adjuvant HIPEC in patients at high risk for colorectal peritoneal metastases. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 2020 05; 46(5):737-739. doi: 10.1016/j.ejso.2020.02.010. [PMID: 32107093]
  • Andrea Gallioli, Romain Boissier, Angelo Territo, Helena Vila Reyes, Francesco Sanguedolce, José Maria Gaya, Federica Regis, José Daniel Subiela, Joan Palou, Alberto Breda. Adjuvant Single-Dose Upper Urinary Tract Instillation of Mitomycin C After Therapeutic Ureteroscopy for Upper Tract Urothelial Carcinoma: A Single-Centre Prospective Non-Randomized Trial. Journal of endourology. 2020 05; 34(5):573-580. doi: 10.1089/end.2019.0750. [PMID: 32164441]
  • Pamela W Lu, Adam C Fields, Galyna Shabat, Ronald Bleday, Joel E Goldberg, Jennifer Irani, Matthias Stopfkuchen-Evans, Nelya Melnitchouk. Cytoreductive Surgery and HIPEC in an Enhanced Recovery After Surgery Program: A Feasibility Study. The Journal of surgical research. 2020 03; 247(?):59-65. doi: 10.1016/j.jss.2019.10.042. [PMID: 31767280]
  • Ramona Figat, Anita Śliwińska, Anna Stochmal, Agata Soluch, Magdalena Sobczak, Anna Zgadzaj, Katarzyna Sykłowska-Baranek, Agnieszka Pietrosiuk. Antigenotoxic, Anti-photogenotoxic, and Antioxidant Properties of Polyscias filicifolia Shoots Cultivated In Vitro. Molecules (Basel, Switzerland). 2020 Feb; 25(5):. doi: 10.3390/molecules25051090. [PMID: 32121158]
  • W Khan, A S Zugail, E Blanc, Y Neuziller, T Lebret. Reasons for intravesical instillation postponement during adjuvant treatment of non-muscle-invasive bladder cancer: A prospective study. Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie. 2020 Feb; 30(2):75-79. doi: 10.1016/j.purol.2019.11.007. [PMID: 31953014]
  • Alberto Gabizon, Hilary Shmeeda, Esther Tahover, Gleb Kornev, Yogita Patil, Yasmine Amitay, Patricia Ohana, Eli Sapir, Samuel Zalipsky. Development of Promitil®, a lipidic prodrug of mitomycin c in PEGylated liposomes: From bench to bedside. Advanced drug delivery reviews. 2020; 154-155(?):13-26. doi: 10.1016/j.addr.2020.07.027. [PMID: 32777239]
  • Wei Phin Tan, Andrew Chang, Steven C Brousell, Dominic C Grimberg, Joseph J Fantony, Thomas A Longo, Wiguins Etienne, Ivan Spasojevic, Paolo Maccarini, Brant A Inman. Safety and efficacy of intravesical chemotherapy and hyperthermia in the bladder: results of a porcine study. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2020; 37(1):854-860. doi: 10.1080/02656736.2020.1780328. [PMID: 32664768]
  • Mingchen Ba, Shuzhong Cui, Hui Long, Yuanfeng Gong, Yinbing Wu, Kunpeng Lin, Yinuo Tu, Bahuo Zhang, Wanbo Wu. Development of a high-precision bladder hyperthermic intracavitary chemotherapy device for bladder cancer and pharmacokinetic study. BMC urology. 2019 Dec; 19(1):126. doi: 10.1186/s12894-019-0543-8. [PMID: 31795980]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Dorota Żelaszczyk, Magdalena Jakubczyk, Karolina Pytka, Anna Rapacz, Maria Walczak, Paulina Janiszewska, Katarzyna Pańczyk, Paweł Żmudzki, Karolina Słoczyńska, Henryk Marona, Anna M Waszkielewicz. Design, synthesis and evaluation of activity and pharmacokinetic profile of new derivatives of xanthone and piperazine in the central nervous system. Bioorganic & medicinal chemistry letters. 2019 11; 29(21):126679. doi: 10.1016/j.bmcl.2019.126679. [PMID: 31537425]
  • Tian Zhang, Hoyin Lip, Chunsheng He, Ping Cai, Zhigao Wang, Jeffrey T Henderson, Andrew M Rauth, Xiao Yu Wu. Multitargeted Nanoparticles Deliver Synergistic Drugs across the Blood-Brain Barrier to Brain Metastases of Triple Negative Breast Cancer Cells and Tumor-Associated Macrophages. Advanced healthcare materials. 2019 09; 8(18):e1900543. doi: 10.1002/adhm.201900543. [PMID: 31348614]
  • Omneya Abdalrahman, Alejandra E Rodriguez, Jorge L Alio Del Barrio, Jorge L Alio. Treatment of chronic and extreme ocular hypotension following glaucoma surgery with intraocular platelet-rich plasma: A case report. European journal of ophthalmology. 2019 Jul; 29(4):NP9-NP12. doi: 10.1177/1120672118803515. [PMID: 30295074]
  • Salma Babiker, Mohamed E Elsayed, Ajay Dhaygude, Indira Madgula. A complex case of haemodialysis induced increased intraocular pressure. European journal of ophthalmology. 2019 Jul; 29(1_suppl):15-17. doi: 10.1177/1120672119842481. [PMID: 31014077]
  • Montserrat Rodriguez-Reyes, Javier Marco-Hernandez, Pedro Castro-Rebollo, Dolors Soy-Muner. Interstitial pneumonitis and myelosuppression associated to mitomycin C urinary tract instillations: A case report. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners. 2019 Apr; 25(3):739-742. doi: 10.1177/1078155218760160. [PMID: 29475405]
  • Waad A Al-Otaibi, Mayson H Alkhatib, Abdulwahab N Wali. Evaluation of Antitumor Activity and Hepatoprotective Effect of Mitomycin C Solubilized in Chamomile Oil Nanoemulsion. Anti-cancer agents in medicinal chemistry. 2019; 19(10):1232-1242. doi: 10.2174/1871520619666190408114732. [PMID: 30961514]
  • Federico Mendoza-Sánchez, Wenceslao G Ángeles-Bueno, Gustavo A Montes-López, Diego F Mendoza-Medina, José M Díaz-Sifuentes, Jacob E Pérez-Landeros. Use of synthetic stomata in abdominal carcinomatosis. Case report and literature review. Cirugia y cirujanos. 2019; 87(S1):28-32. doi: 10.24875/ciru.19000605. [PMID: 31501620]
  • Ravish Kapoor, Kristen Ashlee Robinson, Juan Pablo Cata, Pascal Owusu-Agyemang, Jose Miguel Soliz, Michael Hernandez, Paul Mansfield, Brian Badgwell. Assessment of nephrotoxicity associated with combined cisplatin and mitomycin C usage in laparoscopic hyperthermic intraperitoneal chemotherapy. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2019; 36(1):493-498. doi: 10.1080/02656736.2019.1597175. [PMID: 30935256]
  • Serkan Yilmaz, Asli Uçar, Bayram Göktaş. Genotoxic and Genoprotective Potential of Black Mulberry (Morus nigra) Fruit. Anais da Academia Brasileira de Ciencias. 2019; 91(4):e20190337. doi: 10.1590/0001-3765201920190337. [PMID: 31664310]
  • Hidenori Tanaka, Kazuya Takeda, Akihiro Imai. Polyamines alleviate the inhibitory effect of the DNA cross-linking agent mitomycin C on root growth. Plant signaling & behavior. 2019; 14(11):1659687. doi: 10.1080/15592324.2019.1659687. [PMID: 31446839]
  • Zongyong Shi, Shiying Zou, Chao Lu, Boze Wu, Kunlun Huang, Changhui Zhao, Xiaoyun He. Evaluation of the effects of feeding glyphosate-tolerant soybeans (CP4 EPSPS) on the testis of male Sprague-Dawley rats. GM crops & food. 2019; 10(3):181-190. doi: 10.1080/21645698.2019.1649565. [PMID: 31366287]
  • Keiichi Itoh, Shoji Masumori, Daisuke Mukai, Hiroyuki Sakakibara, Michiko Yasuda, Kayoko Shimoi. Dosage time affects alkylating agents induced micronuclei in mouse peripheral blood reticulocytes through the function of erythropoietin. The Journal of toxicological sciences. 2019; 44(4):273-282. doi: 10.2131/jts.44.273. [PMID: 30944280]
  • Shun Matsuda, Sayaka Wanibuchi, Toshihiko Kasahara. Quantitative analysis of γH2AX reveals distinct responses in multiple mouse organs after administration of mitomycin C or ethyl methanesulfonate. Mutagenesis. 2018 12; 33(5-6):371-378. doi: 10.1093/mutage/gey040. [PMID: 30590785]
  • Adithya Balasubramanian, Michael J Metcalfe, Gavin Wagenheim, Lianchun Xiao, John Papadopoulos, Neema Navai, John W Davis, Jose A Karam, Ashish M Kamat, Christopher G Wood, Colin P Dinney, Surena F Matin. Salvage topical therapy for upper tract urothelial carcinoma. World journal of urology. 2018 Dec; 36(12):2027-2034. doi: 10.1007/s00345-018-2349-9. [PMID: 29804202]
  • Sarah Herwest, Carolin Albers, Maren Schmiester, Bastian Salewsky, Werner Hopfenmüller, Antje Meyer, Lars Bertram, Ilja Demuth. The hSNM1B/Apollo variant rs11552449 is associated with cellular sensitivity towards mitomycin C and ionizing radiation. DNA repair. 2018 12; 72(?):93-98. doi: 10.1016/j.dnarep.2018.09.004. [PMID: 30262195]
  • Joshua K Elson, Lisa A Kachnic, Jordan R Kharofa. Intensity-modulated radiotherapy improves survival and reduces treatment time in squamous cell carcinoma of the anus: A National Cancer Data Base study. Cancer. 2018 11; 124(22):4383-4392. doi: 10.1002/cncr.31721. [PMID: 30329160]
  • Eun Jung Park, Junhyun Ahn, Sang Won Gwak, Kyung Su Park, Seung Hyuk Baik, Sung-Joo Hwang. Pharmacologic Properties of the Carrier Solutions for Hyperthermic Intraperitoneal Chemotherapy: Comparative Analyses Between Water and Lipid Carrier Solutions in the Rat Model. Annals of surgical oncology. 2018 Oct; 25(11):3185-3192. doi: 10.1245/s10434-018-6628-x. [PMID: 30027459]
  • Waad A Al-Otaibi, Mayson H Alkhatib, Abdulwahab Noor Wali. Cytotoxicity and apoptosis enhancement in breast and cervical cancer cells upon coadministration of mitomycin C and essential oils in nanoemulsion formulations. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2018 Oct; 106(?):946-955. doi: 10.1016/j.biopha.2018.07.041. [PMID: 30119267]
  • Burkhard Ubrig, Stephan Roth, Anselm Boy. Title Not Available. Aktuelle Urologie. 2018 Sep; 49(5):437-441. doi: 10.1055/s-0043-116806. [PMID: 30184602]
  • Ni Zhen, Lei Jin, Ji Ma, Jiabei Zhu, Song Gu, Jing Wang, Qiuhui Pan, Xiaorong Ni, Min Xu. Ginsenoside Rg1 impairs homologous recombination repair by targeting CtBP-interacting protein and sensitizes hepatoblastoma cells to DNA damage. Anti-cancer drugs. 2018 09; 29(8):756-766. doi: 10.1097/cad.0000000000000646. [PMID: 29952772]
  • S M Attia, M A Al-Hamamah, M R Alotaibi, G I Harisa, M M Attia, S F Ahmad, M A Ansari, A Nadeem, S A Bakheet. Investigation of belinostat-induced genomic instability by molecular cytogenetic analysis and pathway-focused gene expression profiling. Toxicology and applied pharmacology. 2018 07; 350(?):43-51. doi: 10.1016/j.taap.2018.05.002. [PMID: 29733868]
  • Rea D Signorell, Paola Luciani, Davide Brambilla, Jean-Christophe Leroux. Pharmacokinetics of lipid-drug conjugates loaded into liposomes. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2018 Jul; 128(?):188-199. doi: 10.1016/j.ejpb.2018.04.003. [PMID: 29678733]
  • Ayşe Yavuz Kocaman, Müge Güzelkokar. The genotoxic and antigenotoxic potential of the methanolic root extract of Glycyrrhiza glabra L. on human peripheral blood lymphocytes. Drug and chemical toxicology. 2018 Jul; 41(3):368-375. doi: 10.1080/01480545.2018.1435686. [PMID: 29447011]
  • Sarah Röhrig, Annika Dorn, Janina Enderle, Angelina Schindele, Natalie J Herrmann, Alexander Knoll, Holger Puchta. The RecQ-like helicase HRQ1 is involved in DNA crosslink repair in Arabidopsis in a common pathway with the Fanconi anemia-associated nuclease FAN1 and the postreplicative repair ATPase RAD5A. The New phytologist. 2018 06; 218(4):1478-1490. doi: 10.1111/nph.15109. [PMID: 29577315]
  • Michael Yulish, Ahmed Khatib, Joseph Pikkel. Systemic Absorption of Mitomycin-C When Used in Pterygium Surgery. Cornea. 2018 Jun; 37(6):746-747. doi: 10.1097/ico.0000000000001506. [PMID: 29303888]
  • Julia Waizenegger, Albert Braeuning, Markus Templin, Alfonso Lampen, Stefanie Hessel-Pras. Structure-dependent induction of apoptosis by hepatotoxic pyrrolizidine alkaloids in the human hepatoma cell line HepaRG: Single versus repeated exposure. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2018 Apr; 114(?):215-226. doi: 10.1016/j.fct.2018.02.036. [PMID: 29458164]
  • Kaori Taniguchi, Mariko Funasaki, Akio Kishida, Samir K Sadhu, Firoj Ahmed, Masami Ishibashi, Ayumi Ohsaki. Two new coumarins and a new xanthone from the leaves of Rhizophora mucronata. Bioorganic & medicinal chemistry letters. 2018 04; 28(6):1063-1066. doi: 10.1016/j.bmcl.2018.02.022. [PMID: 29475587]
  • Christian Andreas Radu, Sebastian Fischer, Yannick Diehm, Otto Hetzel, Florian Neubrech, Laura Dittmar, Christian Kleist, Martha Maria Gebhard, Peter Terness, Ulrich Kneser, Jurij Kiefer. The combination of mitomycin-induced blood cells with a temporary treatment of ciclosporin A prolongs allograft survival in vascularized composite allotransplantation. Langenbeck's archives of surgery. 2018 Feb; 403(1):83-92. doi: 10.1007/s00423-017-1616-3. [PMID: 28823033]
  • Christian Morath, Anita Schmitt, Florian Kälble, Martin Zeier, Michael Schmitt, Flavius Sandra-Petrescu, Gerhard Opelz, Peter Terness, Matthias Schaier, Christian Kleist. Cell therapeutic approaches to immunosuppression after clinical kidney transplantation. Pediatric nephrology (Berlin, Germany). 2018 02; 33(2):199-213. doi: 10.1007/s00467-017-3599-2. [PMID: 28229281]
  • Xiaoqin Yu, Qingqing Zhang, Li Tian, Zhiyong Guo, Chengxiong Liu, Jianfeng Chen, Weaam Ebrahim, Zhen Liu, Peter Proksch, Kun Zou. Germacrane-Type Sesquiterpenoids with Antiproliferative Activities from Eupatorium chinense. Journal of natural products. 2018 01; 81(1):85-91. doi: 10.1021/acs.jnatprod.7b00693. [PMID: 29280632]
  • Zhibo Guan, Juan Wu, Cancan Wang, Fang Zhang, Yinan Wang, Miao Wang, Min Zhao, Chunjie Zhao. Investigation of the preventive effect of Sijunzi decoction on mitomycin C-induced immunotoxicity in rats by 1H NMR and MS-based untargeted metabolomic analysis. Journal of ethnopharmacology. 2018 Jan; 210(?):179-191. doi: 10.1016/j.jep.2017.08.021. [PMID: 28866044]
  • G Schooneveldt, H P Kok, A Bakker, E D Geijsen, M C C M Hulshof, T M de Reijke, J Crezee. The effect of air pockets in the urinary bladder on the temperature distribution during loco-regional hyperthermia treatment of bladder cancer patients. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2018; 35(1):441-449. doi: 10.1080/02656736.2018.1506890. [PMID: 30303415]
  • Dhamraa Waleed Al-Dualimi, Aman Shah Abdul Majid, Sarah Furqan Faisal Al-Shimary, Amal Aziz Al-Saadi, Raghdaa Al Zarzour, Muhammad Asif, Chern Ein Oon, Amin Malik Shah Abdul Majid. 50\% Ethanol extract of Orthosiphon stamineus modulates genotoxicity and clastogenicity induced by mitomycin C. Drug and chemical toxicology. 2018 Jan; 41(1):82-88. doi: 10.1080/01480545.2017.1317785. [PMID: 28635332]
  • Mouna Maatouk, Nadia Mustapha, Imen Mokdad-Bzeouich, Hind Chaaban, Irina Ioannou, Kamel Ghedira, Mohamed Ghoul, Leila Chekir-Ghedira. Heated naringin mitigate the genotoxicity effect of Mitomycin C in BALB/c mice through enhancing the antioxidant status. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2018 Jan; 97(?):1417-1423. doi: 10.1016/j.biopha.2017.11.027. [PMID: 29156531]
  • Xiaohui Wei, Yogita Patil, Patricia Ohana, Yasmine Amitay, Hilary Shmeeda, Alberto Gabizon, Yechezkel Barenholz. Characterization of Pegylated Liposomal Mitomycin C Lipid-Based Prodrug (Promitil) by High Sensitivity Differential Scanning Calorimetry and Cryogenic Transmission Electron Microscopy. Molecular pharmaceutics. 2017 12; 14(12):4339-4345. doi: 10.1021/acs.molpharmaceut.6b00865. [PMID: 28045540]
  • Xi-Han Guo, Juan Ni, Jing-Lun Xue, Xu Wang. Phyllanthus emblica Linn. fruit extract potentiates the anticancer efficacy of mitomycin C and cisplatin and reduces their genotoxicity to normal cells in vitro. Journal of Zhejiang University. Science. B. 2017 Dec; 18(12):1031-1045. doi: 10.1631/jzus.b1600542. [PMID: 29204983]
  • Sandhya Kumari, Guruprasad Nayak, Sonu T Lukose, Sneha Guruprasad Kalthur, Nandini Bhat, Aswathi R Hegde, Srinivas Mutalik, Guruprasad Kalthur, Satish Kumar Adiga. Indian propolis ameliorates the mitomycin C-induced testicular toxicity by reducing DNA damage and elevating the antioxidant activity. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2017 Nov; 95(?):252-263. doi: 10.1016/j.biopha.2017.08.065. [PMID: 28846983]
  • Rui Xue Zhang, Tian Zhang, King Chen, Ji Cheng, Paris Lai, Andrew M Rauth, K Sandy Pang, Xiao Yu Wu. Sample Extraction and Simultaneous Chromatographic Quantitation of Doxorubicin and Mitomycin C Following Drug Combination Delivery in Nanoparticles to Tumor-bearing Mice. Journal of visualized experiments : JoVE. 2017 10; ?(128):. doi: 10.3791/56159. [PMID: 29053672]
  • Francesco Pierconti, Patrizia Straccia, Sacco Emilio, Pier Francesco Bassi, Ivana De Pascalis, Rita C Marques, Metka Volavsek, Luigi M Larocca, Antonio Lopez-Beltran. Cytological and histological changes in the urothelium produced by electromotive drug administration (EMDA) and by the combination of intravescical hyperthermia and chemotherapy (thermochemotherapy). Pathology, research and practice. 2017 09; 213(9):1078-1081. doi: 10.1016/j.prp.2017.07.026. [PMID: 28843746]
  • Michael Metcalfe, Gavin Wagenheim, Lianchun Xiao, John Papadopoulos, Neema Navai, John W Davis, Jose A Karam, Ashish M Kamat, Christopher G Wood, Colin P Dinney, Surena F Matin. Induction and Maintenance Adjuvant Mitomycin C Topical Therapy for Upper Tract Urothelial Carcinoma: Tolerability and Intermediate Term Outcomes. Journal of endourology. 2017 09; 31(9):946-953. doi: 10.1089/end.2016.0871. [PMID: 28731777]
  • Bhaskar K Somani. Editorial Comment on: Induction and Maintenance Adjuvant Mitomycin C Topical Therapy for Upper Tract Urothelial Carcinoma: Tolerability and Intermediate Term Outcomes by Metcalfe et al. Journal of endourology. 2017 09; 31(9):954-955. doi: 10.1089/end.2017.0536. [PMID: 28762779]
  • Nina Ashraf-Kashani, John Bell. Haemodynamic changes during hyperthermic intra-thoracic chemotherapy for pseudomyxoma peritonei. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2017 09; 33(6):675-678. doi: 10.1080/02656736.2017.1300944. [PMID: 28540781]
  • Stefano Guadagni, Giammaria Fiorentini, Marco Clementi, Paola Palumbo, Andrea Mambrini, Francesco Masedu. Mitomycin C hypoxic pelvic perfusion for unresectable recurrent rectal cancer: pharmacokinetic comparison of surgical and percutaneous techniques. Updates in surgery. 2017 Sep; 69(3):403-410. doi: 10.1007/s13304-017-0480-6. [PMID: 28791628]
  • Srikanth Vudhgiri, Dhevendar Koude, Dileep Kumar Veeragoni, Sunil Misra, R B N Prasad, Ram Chandra Reddy Jala. Synthesis and biological evaluation of 5-fatty-acylamido-1, 3, 4-thiadiazole-2-thioglycosides. Bioorganic & medicinal chemistry letters. 2017 08; 27(15):3370-3373. doi: 10.1016/j.bmcl.2017.06.004. [PMID: 28615134]
  • Tian Zhang, Preethy Prasad, Ping Cai, Chunsheng He, Dan Shan, Andrew Michael Rauth, Xiao Yu Wu. Dual-targeted hybrid nanoparticles of synergistic drugs for treating lung metastases of triple negative breast cancer in mice. Acta pharmacologica Sinica. 2017 Jun; 38(6):835-847. doi: 10.1038/aps.2016.166. [PMID: 28216624]
  • Mingchen Ba, Shuzhong Cui, Bin Wang, Hui Long, Zhaofei Yan, Shuai Wang, Yinbing Wu, Yuanfeng Gong. Bladder intracavitary hyperthermic perfusion chemotherapy for the prevention of recurrence of non-muscle invasive bladder cancer after transurethral resection. Oncology reports. 2017 May; 37(5):2761-2770. doi: 10.3892/or.2017.5570. [PMID: 28405683]
  • Nicholas M Donin, Dalit Strauss-Ayali, Yael Agmon-Gerstein, Nadav Malchi, Andrew T Lenis, Stuart Holden, Allan J Pantuck, Arie S Belldegrun, Karim Chamie. Serial retrograde instillations of sustained release formulation of mitomycin C to the upper urinary tract of the Yorkshire swine using a thermosensitive polymer: Safety and feasibility. Urologic oncology. 2017 05; 35(5):272-278. doi: 10.1016/j.urolonc.2016.11.019. [PMID: 28065395]