3-NITROFLUORANTHENE (BioDeep_00000009886)

   


代谢物信息卡片


3-NITROFLUORANTHENE

化学式: C16H9NO2 (247.0633)
中文名称: 3-硝基荧蒽
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C2C(=C1)C3=C4C2=CC=CC4=C(C=C3)[N+](=O)[O-]
InChI: InChI=1S/C16H9NO2/c18-17(19)15-9-8-13-11-5-2-1-4-10(11)12-6-3-7-14(15)16(12)13/h1-9H

描述信息

D009676 - Noxae > D002273 - Carcinogens
D009676 - Noxae > D009153 - Mutagens

同义名列表

2 个代谢物同义名

3-NITROFLUORANTHENE; 3-Nitrofluoranthene



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 15 AHR, ATM, CASP3, CASP8, CHEK2, CYP1A1, ESR1, MAPK14, MAPK8, MPI, PIK3C3, PIK3CA, PRPF19, SERPINB1, XDH
Peripheral membrane protein 3 CYP1A1, CYP1B1, ESR1
Endoplasmic reticulum membrane 2 CYP1A1, CYP1B1
Cytoplasmic vesicle, autophagosome 1 PIK3C3
Nucleus 12 AHR, ATM, CASP3, CASP8, CEBPA, CHEK2, ENDOG, ESR1, H2AX, MAPK14, MAPK8, PRPF19
autophagosome 1 PIK3C3
cytosol 11 AHR, ATM, CASP3, CASP8, ESR1, MAPK14, MAPK8, MPI, PIK3C3, PIK3CA, XDH
phosphatidylinositol 3-kinase complex, class III 1 PIK3C3
centrosome 2 ATM, H2AX
nucleoplasm 11 AHR, ATM, CASP3, CASP8, CEBPA, CHEK2, ESR1, H2AX, MAPK14, MAPK8, PRPF19
RNA polymerase II transcription regulator complex 1 CEBPA
Cell membrane 2 ESR1, TNF
Cytoplasmic side 1 ESR1
lamellipodium 2 CASP8, PIK3CA
Synapse 1 MAPK8
cell surface 1 TNF
glutamatergic synapse 3 CASP3, MAPK14, PIK3C3
Golgi apparatus 2 CHEK2, ESR1
mitochondrial inner membrane 2 CYP1A1, ENDOG
neuronal cell body 2 CASP3, TNF
endosome 1 PIK3C3
plasma membrane 3 ESR1, PIK3CA, TNF
Membrane 5 CYP1B1, ESR1, PIK3C3, PRPF19, SERPINB1
axon 1 MAPK8
extracellular exosome 3 H2AX, MPI, SERPINB1
extracellular space 3 SERPINB1, TNF, XDH
perinuclear region of cytoplasm 1 PIK3CA
intercalated disc 1 PIK3CA
mitochondrion 5 CASP8, CYP1A1, CYP1B1, ENDOG, MAPK14
protein-containing complex 3 AHR, CASP8, ESR1
intracellular membrane-bounded organelle 4 ATM, CEBPA, CYP1A1, CYP1B1
Microsome membrane 2 CYP1A1, CYP1B1
postsynaptic density 1 CASP3
Secreted 1 SERPINB1
extracellular region 3 MAPK14, SERPINB1, TNF
mitochondrial outer membrane 1 CASP8
transcription regulator complex 3 AHR, CEBPA, ESR1
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 ATM
external side of plasma membrane 1 TNF
cytoplasmic vesicle 1 ATM
nucleolus 2 ATM, CEBPA
midbody 1 PIK3C3
Early endosome 1 SERPINB1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Cell projection, lamellipodium 1 CASP8
Mitochondrion inner membrane 1 CYP1A1
Membrane raft 1 TNF
Cytoplasm, cytoskeleton, spindle 1 PRPF19
spindle 2 ATM, PRPF19
GABA-ergic synapse 1 PIK3C3
Peroxisome 2 PIK3C3, XDH
sarcoplasmic reticulum 1 XDH
Peroxisome matrix 1 ATM
peroxisomal matrix 1 ATM
PML body 1 CHEK2
collagen-containing extracellular matrix 1 SERPINB1
axoneme 1 PIK3C3
nuclear speck 3 H2AX, MAPK14, PRPF19
Late endosome 1 PIK3C3
chromatin 3 AHR, CEBPA, ESR1
phagocytic cup 1 TNF
phagocytic vesicle membrane 1 PIK3C3
Chromosome 1 H2AX
cytoskeleton 1 CASP8
cytoplasmic ribonucleoprotein granule 1 SERPINB1
spindle pole 1 MAPK14
spliceosomal complex 1 PRPF19
site of double-strand break 3 ATM, H2AX, PRPF19
Lipid droplet 1 PRPF19
phagophore assembly site 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type I 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type II 1 PIK3C3
aryl hydrocarbon receptor complex 1 AHR
Nucleus, nucleoplasm 1 PRPF19
euchromatin 1 ESR1
cell body 1 CASP8
replication fork 1 H2AX
ficolin-1-rich granule lumen 1 MAPK14
secretory granule lumen 2 MAPK14, SERPINB1
male germ cell nucleus 1 H2AX
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
XY body 1 H2AX
extrinsic component of synaptic vesicle membrane 1 ATM
presynaptic endosome 1 PIK3C3
condensed nuclear chromosome 1 H2AX
[Isoform 1]: Nucleus 1 ESR1
U2-type catalytic step 1 spliceosome 1 PRPF19
basal dendrite 1 MAPK8
CD95 death-inducing signaling complex 1 CASP8
death-inducing signaling complex 2 CASP3, CASP8
ripoptosome 1 CASP8
nucleosome 1 H2AX
catalytic step 2 spliceosome 1 PRPF19
Prp19 complex 1 PRPF19
U2-type catalytic step 2 spliceosome 1 PRPF19
DNA repair complex 1 ATM
site of DNA damage 1 H2AX
postsynaptic endosome 1 PIK3C3
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
Autolysosome 1 PIK3C3
Cytolytic granule 1 SERPINB1
C/EBP complex 1 CEBPA
CHOP-C/EBP complex 1 CEBPA
nuclear aryl hydrocarbon receptor complex 1 AHR
cytosolic aryl hydrocarbon receptor complex 1 AHR
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[Isoform 4]: Nucleus, nucleolus 1 CEBPA
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Haifeng Sun, Yanli Nan, Ruijie Feng, Ruiyao Ma. Novel method for in situ investigation into graphene quantum dots effects on the adsorption of nitrated polycyclic aromatic hydrocarbons by crop leaf surfaces. Ecotoxicology and environmental safety. 2018 Oct; 162(?):10-16. doi: 10.1016/j.ecoenv.2018.06.059. [PMID: 29957403]
  • Nana Asare, Xavier Tekpli, Mary Rissel, Anita Solhaug, Nina Landvik, Valerie Lecureur, Normand Podechard, Gunnar Brunborg, Marit Låg, Dominique Lagadic-Gossmann, Jørn A Holme. Signalling pathways involved in 1-nitropyrene (1-NP)-induced and 3-nitrofluoranthene (3-NF)-induced cell death in Hepa1c1c7 cells. Mutagenesis. 2009 Nov; 24(6):481-93. doi: 10.1093/mutage/gep032. [PMID: 19703935]
  • Nana Asare, Dominique Lagadic-Gossmann, Jørn A Holme. 3-nitrofluoranthene (3-NF)-induced apoptosis and programmed necrosis. Autophagy. 2009 Jul; 5(5):751-2. doi: 10.4161/auto.5.5.8790. [PMID: 19448393]
  • T Ohe, K Marutani, S Nakase. Catechins are not major components responsible for anti-genotoxic effects of tea extracts against nitroarenes. Mutation research. 2001 Sep; 496(1-2):75-81. doi: 10.1016/s1383-5718(01)00220-0. [PMID: 11551482]
  • R Edenharder, X Tang. Inhibition of the mutagenicity of 2-nitrofluorene, 3-nitrofluoranthene and 1-nitropyrene by flavonoids, coumarins, quinones and other phenolic compounds. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 1997 Mar; 35(3-4):357-72. doi: 10.1016/s0278-6915(97)00125-7. [PMID: 9207898]