Paeoniflorigenone (BioDeep_00000000908)
PANOMIX_OTCML-2023 natural product
代谢物信息卡片
化学式: C17H18O6 (318.1103)
中文名称: 芍药甙元酮, 芍药苷元酮
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 95.29%
分子结构信息
SMILES: CC12CC(=O)C3CC1(O)OC(O2)C3COC(=O)c1ccccc1
InChI: InChI=1S/C17H18O6/c1-16-8-13(18)11-7-17(16,20)23-15(22-16)12(11)9-21-14(19)10-5-3-2-4-6-10/h2-6,11-12,15,20H,7-9H2,1H3/t11-,12-,15+,16+,17-/m1/s1
描述信息
A natural product found in Paeonia rockii subspeciesrockii.
Paeoniflorigenone is a terpenoid with formula C17H18O6, isolated from several species of Paeoniae. It has a role as a neuromuscular agent and a plant metabolite. It is a benzoate ester, a monoterpenoid, a cyclic acetal, an alicyclic ketone, a bridged compound and a lactol.
[(1S,3S,6R,8R,10S)-8-hydroxy-3-methyl-5-oxo-2,9-dioxatricyclo[4.3.1.03,8]decan-10-yl]methyl benzoate is a natural product found in Paeonia lactiflora, Paeonia clusii, and other organisms with data available.
A terpenoid with formula C17H18O6, isolated from several species of Paeoniae.
同义名列表
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:69582
- ChEBI: CHEBI:132788
- KEGG: C17453
- PubChem: 70698143
- PubChem: 22116986
- MeSH: paeoniflorigenone
- KNApSAcK: C00010954
- CAS: 80454-42-8
- medchemexpress: HY-N3119
- PMhub: MS000025816
- MetaboLights: MTBLC69582
- MetaboLights: MTBLC132788
- PubChem: 163311801
- LOTUS: LTS0078788
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
15 个相关的物种来源信息
- 2759 - Eukaryota: LTS0078788
- 3398 - Magnoliopsida: LTS0078788
- 13625 - Paeonia: 10.1254/JJP.35.61
- 13625 - Paeonia: LTS0078788
- 40705 - Paeonia clusii: 10.1515/ZNC-2002-3-406
- 35924 - Paeonia lactiflora:
- 35924 - Paeonia lactiflora: 10.1080/14756360802667977
- 40717 - Paeonia peregrina: 10.1016/S0031-9422(97)00683-3
- 45171 - Paeonia suffruticosa:
- 45171 - Paeonia suffruticosa: 10.1021/NP9002004
- 45171 - Paeonia suffruticosa: LTS0078788
- 24943 - Paeoniaceae: LTS0078788
- 35493 - Streptophyta: LTS0078788
- 58023 - Tracheophyta: LTS0078788
- 33090 - Viridiplantae: LTS0078788
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Zhiyan Wu, Xingrong Tang. Bioinformatics analysis and experimental validation revealed that Paeoniflorigenone effectively mitigates cerebral ischemic stroke by suppressing oxidative stress and inflammation.
Scientific reports.
2024 03; 14(1):5580. doi:
10.1038/s41598-024-55041-5. [PMID: 38448479] - Kyung-Ran Park, Hanna Lee, Soo Hyun Kim, Hyung-Mun Yun. Paeoniflorigenone regulates apoptosis, autophagy, and necroptosis to induce anti-cancer bioactivities in human head and neck squamous cell carcinomas.
Journal of ethnopharmacology.
2022 Apr; 288(?):115000. doi:
10.1016/j.jep.2022.115000. [PMID: 35051602] - Ying Huang, Osamu Ohno, Kiyotake Suenaga, Kenji Miyamoto. Apoptosis-inducing activity and antiproliferative effect of Paeoniflorigenone from moutan cortex.
Bioscience, biotechnology, and biochemistry.
2017 Jun; 81(6):1106-1113. doi:
10.1080/09168451.2017.1300517. [PMID: 28317437] - Hong-Yu Hu, Yu Yang, Neng-Jiang Yu, Yi-Min Zhao. [Study on chemical constituents of bark of Paeonia suffruticosa].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2006 Nov; 31(21):1793-5. doi:
. [PMID: 17260795] - C F Wu. [A review on the pharmacology of Paeonia lactiflora and its chemical components].
Zhong yao tong bao (Beijing, China : 1981).
1985 Jun; 10(6):43-5. doi:
". [PMID: 2934174]
