herbimycin a (BioDeep_00000897217)
Volatile Flavor Compounds
代谢物信息卡片
herbimycin a
化学式: C30H42N2O9 (574.2890162)
中文名称: 除莠霉素A
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C=C(C1OC)C2=O)C)OC)OC(=O)N)C)C)OC)OC
InChI: InChI=1S/C30H42N2O9/c1-16-10-9-11-23(37-5)28(41-30(31)36)18(3)12-17(2)27(40-8)24(38-6)13-19(4)26(39-7)21-14-20(33)15-22(25(21)34)32-29(16)35/h9-12,14-15,17,19,23-24,26-28H,13H2,1-8H3,(H2,31,36)(H,32,35)/b11-9-,16-10+,18-12+/t17-,19-,23-,24-,26+,27+,28-/m0/s1
描述信息
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C259 - Antineoplastic Antibiotic
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D012294 - Rifamycins
D000970 - Antineoplastic Agents
D004791 - Enzyme Inhibitors
同义名列表
2 个代谢物同义名
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:5674
- PubChem: 5311102
- ChEMBL: CHEMBL480499
- CAS: 70563-58-5
- KEGG: C11225
- PubChem: 13404
- KNApSAcK: 5674
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 3708 - Brassica napus: 10.3389/FNUT.2022.822033
- 1912 - Streptomyces hygroscopicus:
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Guoyan Zhang, Shiliang Gui, Weiqun Wang, Dexin Meng, Qingmin Meng, Haiyan Luan, Rixin Zhao, Jiatian Zhang, Hongyu Sui. Acute stimulatory effect of tumor necrosis factor on the basolateral 50 pS K channels in the thick ascending limb of the rat kidney.
Molecular medicine reports.
2018 Nov; 18(5):4733-4738. doi:
10.3892/mmr.2018.9475. [PMID: 30221721] - Ya A Sheremet, A I Yemets, A Azmi, K Vissenberg, J P Verbelen, Ya B Blume. Effects of tyrosine kinase and phosphatase inhibitors on mitosis progression in synchronized tobacco BY-2 cells.
TSitologiia i genetika.
2012 Sep; 46(5):3-11. doi:
. [PMID: 23342643] - Ya A Sheremet, A I Yemets, Ya B Blume. Inhibitors of tyrosine kinases and phosphatases as a tool for the investigation of microtubule role in plant cold response.
TSitologiia i genetika.
2012 Jan; 46(1):3-9. doi:
. [PMID: 22420214] - G Daoud, F Le bellego, J Lafond. PP2 regulates human trophoblast cells differentiation by activating p38 and ERK1/2 and inhibiting FAK activation.
Placenta.
2008 Oct; 29(10):862-70. doi:
10.1016/j.placenta.2008.07.011. [PMID: 18783823] - Janine Voyer, John J Heikkila. Comparison of the effect of heat shock factor inhibitor, KNK437, on heat shock- and chemical stress-induced hsp30 gene expression in Xenopus laevis A6 cells.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.
2008 Oct; 151(2):253-61. doi:
10.1016/j.cbpa.2008.07.004. [PMID: 18675372] - Mike O Karl, Wolfram Kroeger, Soenke Wimmers, Vladimir M Milenkovic, Monika Valtink, Katrin Engelmann, Olaf Strauss. Endogenous Gas6 and Ca2+ -channel activation modulate phagocytosis by retinal pigment epithelium.
Cellular signalling.
2008 Jun; 20(6):1159-68. doi:
10.1016/j.cellsig.2008.02.005. [PMID: 18395422] - Alla Yemets, Yarina Sheremet, Kris Vissenberg, Jürgen Van Orden, Jean-Pierre Verbelen, Yaroslav B Blume. Effects of tyrosine kinase and phosphatase inhibitors on microtubules in Arabidopsis root cells.
Cell biology international.
2008 Jun; 32(6):630-7. doi:
10.1016/j.cellbi.2008.01.013. [PMID: 18343165] - Daohong Lin, Erik-Jan Kamsteeg, Yan Zhang, Yan Jin, Hyacinth Sterling, Peng Yue, Marcel Roos, Amy Duffield, Joanna Spencer, Michael Caplan, Wen-Hui Wang. Expression of tetraspan protein CD63 activates protein-tyrosine kinase (PTK) and enhances the PTK-induced inhibition of ROMK channels.
The Journal of biological chemistry.
2008 Mar; 283(12):7674-81. doi:
10.1074/jbc.m705574200. [PMID: 18211905] - Winfried Goettsch, Corina Gryczka, Thomas Korff, Evelyn Ernst, Claudia Goettsch, Jochen Seebach, Hans-Joachim Schnittler, Hellmut G Augustin, Henning Morawietz. Flow-dependent regulation of angiopoietin-2.
Journal of cellular physiology.
2008 Feb; 214(2):491-503. doi:
10.1002/jcp.21229. [PMID: 17960565] - Gregory D Rushing, L D Britt. Inhibition of NF-KB does not induce c-Jun N-terminal kinase-mediated apoptosis in reperfusion injury.
Journal of the American College of Surgeons.
2007 May; 204(5):964-7; discussion 967. doi:
10.1016/j.jamcollsurg.2007.01.029. [PMID: 17481520] - Hung Bae Chang, Jae-Heon Kim. Antioxidant properties of dihydroherbimycin A from a newly isolated Streptomyces sp.
Biotechnology letters.
2007 Apr; 29(4):599-603. doi:
10.1007/s10529-006-9288-z. [PMID: 17206369] - Shin-ichiro Nakagawa, Takuya Umehara, Chiho Matsuda, Shusuke Kuge, Masayuki Sudoh, Michinori Kohara. Hsp90 inhibitors suppress HCV replication in replicon cells and humanized liver mice.
Biochemical and biophysical research communications.
2007 Feb; 353(4):882-8. doi:
10.1016/j.bbrc.2006.12.117. [PMID: 17196931] - P R Sudhakaran, A Radhika, S S Jacob. Monocyte macrophage differentiation in vitro: Fibronectin-dependent upregulation of certain macrophage-specific activities.
Glycoconjugate journal.
2007 Jan; 24(1):49-55. doi:
10.1007/s10719-006-9011-2. [PMID: 17115276] - Dimin Li, Zhijian Wang, Peng Sun, Yan Jin, Dao-Hong Lin, Steven C Hebert, Gerhard Giebisch, Wen-Hui Wang. Inhibition of MAPK stimulates the Ca2+ -dependent big-conductance K channels in cortical collecting duct.
Proceedings of the National Academy of Sciences of the United States of America.
2006 Dec; 103(51):19569-74. doi:
10.1073/pnas.0609555104. [PMID: 17151195] - Yoshiko Fujita, Masanori Yoshizumi, Yuki Izawa, Nermin Ali, Hideki Ohnishi, Yasuhisa Kanematsu, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiaki Tamaki. Transactivation of fetal liver kinase-1/kinase-insert domain-containing receptor by lysophosphatidylcholine induces vascular endothelial cell proliferation.
Endocrinology.
2006 Mar; 147(3):1377-85. doi:
10.1210/en.2005-0644. [PMID: 16322069] - Being-Sun Wung, Ming-Chun Hsu, Chun-Ching Wu, Chia-Wen Hsieh. Piceatannol upregulates endothelial heme oxygenase-1 expression via novel protein kinase C and tyrosine kinase pathways.
Pharmacological research.
2006 Feb; 53(2):113-22. doi:
10.1016/j.phrs.2005.09.006. [PMID: 16243536] - Brenda S Luciano, Sang Hsu, Padma L Channavajhala, Lih-Ling Lin, John W Cuozzo. Phosphorylation of threonine 290 in the activation loop of Tpl2/Cot is necessary but not sufficient for kinase activity.
The Journal of biological chemistry.
2004 Dec; 279(50):52117-23. doi:
10.1074/jbc.m403716200. [PMID: 15466476] - Sumio Yano, Nelly Arroyo, Noriko Yano. SHP2 binds catalase and acquires a hydrogen peroxide-resistant phosphatase activity via integrin-signaling.
FEBS letters.
2004 Nov; 577(3):327-32. doi:
10.1016/j.febslet.2004.10.011. [PMID: 15556604] - Deepak K Sharma, Jennifer C Brown, Amit Choudhury, Timothy E Peterson, Eileen Holicky, David L Marks, Robert Simari, Robert G Parton, Richard E Pagano. Selective stimulation of caveolar endocytosis by glycosphingolipids and cholesterol.
Molecular biology of the cell.
2004 Jul; 15(7):3114-22. doi:
10.1091/mbc.e04-03-0189. [PMID: 15107466] - Sumio Yano, Nelly Arroyo, Noriko Yano. Catalase binds Grb2 in tumor cells when stimulated with serum or ligands for integrin receptors.
Free radical biology & medicine.
2004 Jun; 36(12):1542-54. doi:
10.1016/j.freeradbiomed.2004.04.006. [PMID: 15182856] - Morimasa Amemiya, Honami Mori, Shigeki Imamura, Akira Toyoda, Izumi Funayama, Yasushi Asano, Eiji Kusano, Kaoru Tabei. Stimulation of NHE3 in OKP cells by an autocrine mechanism.
Nephron. Experimental nephrology.
2004; 96(1):e23-30. doi:
10.1159/000075573. [PMID: 14752245] - Yuan Wei, Elisa Babilonia, Paulina L Pedraza, Nicholas R Ferreri, Wen-Hui Wang. Acute application of TNF stimulates apical 70-pS K+ channels in the thick ascending limb of rat kidney.
American journal of physiology. Renal physiology.
2003 Sep; 285(3):F491-7. doi:
10.1152/ajprenal.00104.2003. [PMID: 12890664] - Bradford A Young, Xiufen Sui, Timothy D Kiser, Sang Won Hyun, Ping Wang, Serhan Sakarya, Daniel J Angelini, Kane L Schaphorst, Jeffrey D Hasday, Alan S Cross, Lewis H Romer, Antonino Passaniti, Simeon E Goldblum. Protein tyrosine phosphatase activity regulates endothelial cell-cell interactions, the paracellular pathway, and capillary tube stability.
American journal of physiology. Lung cellular and molecular physiology.
2003 Jul; 285(1):L63-75. doi:
10.1152/ajplung.00423.2002. [PMID: 12626337] - Hyacinth Sterling, Dao-Hong Lin, Yuan Wei, Wen-Hui Wang. Tetanus toxin abolishes exocytosis of ROMK1 induced by inhibition of protein tyrosine kinase.
American journal of physiology. Renal physiology.
2003 Mar; 284(3):F510-7. doi:
10.1152/ajprenal.00309.2002. [PMID: 12556363] - Ho Jae Han, Soo Hyun Park, Yun Jung Lee. Epidermal growth factor regulates Ca2+ uptake in primary cultured renal proximal tubule cells: involvement of cAMP, PKC and cPLA2.
Kidney & blood pressure research.
2003; 26(3):155-64. doi:
10.1159/000071881. [PMID: 12886043] - Daizo Korita, Norimasa Sagawa, Hiroaki Itoh, Shigeo Yura, Masahiro Yoshida, Kazuyo Kakui, Maki Takemura, Chieko Yokoyama, Tadashi Tanabe, Shingo Fujii. Cyclic mechanical stretch augments prostacyclin production in cultured human uterine myometrial cells from pregnant women: possible involvement of up-regulation of prostacyclin synthase expression.
The Journal of clinical endocrinology and metabolism.
2002 Nov; 87(11):5209-19. doi:
10.1210/jc.2002-020531. [PMID: 12414894] - Solène Grazide, Nicolas Maestre, Robert Jan Veldman, Christine Bezombes, Stéphane Maddens, Thierry Levade, Guy Laurent, Jean-Pierre Jaffrézou. Ara-C- and daunorubicin-induced recruitment of Lyn in sphingomyelinase-enriched membrane rafts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2002 Oct; 16(12):1685-7. doi:
10.1096/fj.01-0794fje. [PMID: 12206990] - Toshinori Bito, Sashwati Roy, Chandan K Sen, Toshiro Shirakawa, Akinobu Gotoh, Masato Ueda, Masamitsu Ichihashi, Lester Packer. Flavonoids differentially regulate IFN gamma-induced ICAM-1 expression in human keratinocytes: molecular mechanisms of action.
FEBS letters.
2002 Jun; 520(1-3):145-52. doi:
10.1016/s0014-5793(02)02810-7. [PMID: 12044887] - Yuan Wei, Wen-Hui Wang. Role of the cytoskeleton in mediating effect of vasopressin and herbimycin A on secretory K channels in CCD.
American journal of physiology. Renal physiology.
2002 Apr; 282(4):F680-6. doi:
10.1152/ajprenal.00229.2001. [PMID: 11880329] - Harold A Franch, Xiaonan Wang, Sira Sooparb, Nikia S Brown, Jie Du. Phosphatidylinositol 3-kinase activity is required for epidermal growth factor to suppress proteolysis.
Journal of the American Society of Nephrology : JASN.
2002 Apr; 13(4):903-909. doi:
10.1681/asn.v134903. [PMID: 11912249] - Joan D Ferraris, Chester K Williams, Prita Persaud, Zheng Zhang, Ye Chen, Maurice B Burg. Activity of the TonEBP/OREBP transactivation domain varies directly with extracellular NaCl concentration.
Proceedings of the National Academy of Sciences of the United States of America.
2002 Jan; 99(2):739-44. doi:
10.1073/pnas.241637298. [PMID: 11792870] - Karina Drumm, Boris Bauer, Ruth Freudinger, Michael Gekle. Albumin induces NF-kappaB expression in human proximal tubule-derived cells (IHKE-1).
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.
2002; 12(4):187-96. doi:
10.1159/000066278. [PMID: 12297724] - Tae Han Yuk, Joon Hyeog Kang, Sang Ryoung Lee, Sang Won Yuk, Kwang Gyu Lee, Beum Yong Song, Cheorl Ho Kim, Dong Wook Kim, Il Kim Dong, Tae Kyun Lee, Chang Hyun Lee. Inhibitory effect of Carthamus tinctorius L. seed extracts on bone resorption mediated by tyrosine kinase, COX-2 (cyclooxygenase) and PG (prostaglandin) E2.
The American journal of Chinese medicine.
2002; 30(1):95-108. doi:
10.1142/s0192415x02000119. [PMID: 12067102] - J Wang, E Guan, G Roderiquez, V Calvert, R Alvarez, M A Norcross. Role of tyrosine phosphorylation in ligand-independent sequestration of CXCR4 in human primary monocytes-macrophages.
The Journal of biological chemistry.
2001 Dec; 276(52):49236-43. doi:
10.1074/jbc.m108523200. [PMID: 11668182] - T Sobue, Y Hakeda, Y Kobayashi, H Hayakawa, K Yamashita, T Aoki, M Kumegawa, T Noguchi, T Hayakawa. Tissue inhibitor of metalloproteinases 1 and 2 directly stimulate the bone-resorbing activity of isolated mature osteoclasts.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
2001 Dec; 16(12):2205-14. doi:
10.1359/jbmr.2001.16.12.2205. [PMID: 11760833] - R H Weiss, L L Howard. p73 is a growth-regulated protein in vascular smooth muscle cells and is present at high levels in human atherosclerotic plaque.
Cellular signalling.
2001 Oct; 13(10):727-33. doi:
10.1016/s0898-6568(01)00195-4. [PMID: 11602183] - R M Gu, Y Wei, J R Falck, U M Krishna, W H Wang. Effects of protein tyrosine kinase and protein tyrosine phosphatase on apical K(+) channels in the TAL.
American journal of physiology. Cell physiology.
2001 Oct; 281(4):C1188-95. doi:
10.1152/ajpcell.2001.281.4.c1188. [PMID: 11546655] - J Ruiz, J H Leary, L Jaso-Friedmann. Phosphorylation-induced activation of tilapia nonspecific cytotoxic cells by serum cytokines.
Diseases of aquatic organisms.
2001 Sep; 46(2):129-37. doi:
10.3354/dao046129. [PMID: 11678228] - Y Wei, P Bloom, D Lin, R Gu, W H Wang. Effect of dietary K intake on apical small-conductance K channel in CCD: role of protein tyrosine kinase.
American journal of physiology. Renal physiology.
2001 Aug; 281(2):F206-12. doi:
10.1152/ajprenal.2001.281.2.f206. [PMID: 11457712] - K Drumm, B Gassner, S Silbernagl, M Gekle. Albumin in the mg/l-range activates NF-kappaB in renal proximal tubule-derived cell lines via tyrosine kinases and protein kinase C.
European journal of medical research.
2001 Jun; 6(6):247-58. doi:
. [PMID: 11432793] - R Ye, A Bodero, B B Zhou, K K Khanna, M F Lavin, S P Lees-Miller. The plant isoflavenoid genistein activates p53 and Chk2 in an ATM-dependent manner.
The Journal of biological chemistry.
2001 Feb; 276(7):4828-33. doi:
10.1074/jbc.m004894200. [PMID: 11096068] - L Chen, Y Wang, L K Kairaitis, Y Wang, B H Zhang, D C Harris. Molecular mechanisms by which iron induces nitric oxide synthesis in cultured proximal tubule cells.
Experimental nephrology.
2001; 9(3):198-204. doi:
10.1159/000052612. [PMID: 11340304] - G Roy, M Lombardía, C Palacios, A Serrano, C Cespón, E Ortega, P Eiras, S Lujan, Y Revilla, P Gonzalez-Porqué. Mechanistic aspects of the induction of apoptosis by lauryl gallate in the murine B-cell lymphoma line Wehi 231.
Archives of biochemistry and biophysics.
2000 Nov; 383(2):206-14. doi:
10.1006/abbi.2000.2049. [PMID: 11185555] - F Nozu, C Owyang, Y Tsunoda. Involvement of phosphoinositide 3-kinase and its association with pp60src in cholecystokinin-stimulated pancreatic acinar cells.
European journal of cell biology.
2000 Nov; 79(11):803-9. doi:
10.1078/0171-9335-00108. [PMID: 11139143] - J H Choi, W J Chung, S J Han, H B Lee, I W Choi, H K Lee, K Y Jang, D G Lee, S S Han, K H Park, S Y IM. Selective involvement of reactive oxygen intermediates in platelet-activating factor-mediated activation of NF-kappaB.
Inflammation.
2000 Oct; 24(5):385-98. doi:
10.1023/a:1007068010645. [PMID: 10921504] - F Jow, K Wang. Cloning and functional expression of rKCNQ2 K(+) channel from rat brain.
Brain research. Molecular brain research.
2000 Sep; 80(2):269-78. doi:
10.1016/s0169-328x(00)00146-7. [PMID: 11038262] - A Zeidan, I Nordström, K Dreja, U Malmqvist, P Hellstrand. Stretch-dependent modulation of contractility and growth in smooth muscle of rat portal vein.
Circulation research.
2000 Aug; 87(3):228-34. doi:
10.1161/01.res.87.3.228. [PMID: 10926874] - S A Hobson, S E McNeil, F Lee, K D Rodland. Signal transduction mechanisms linking increased extracellular calcium to proliferation in ovarian surface epithelial cells.
Experimental cell research.
2000 Jul; 258(1):1-11. doi:
10.1006/excr.2000.4910. [PMID: 10912782] - Y Wei, P Bloom, R Gu, W Wang. Protein-tyrosine phosphatase reduces the number of apical small conductance K+ channels in the rat cortical collecting duct.
The Journal of biological chemistry.
2000 Jul; 275(27):20502-7. doi:
10.1074/jbc.m000783200. [PMID: 10787405] - N Endo, E Tashiro, K Umezawa, M Kawada, Y Uehara, Y Doki, I B Weinstein, M Imoto. Herbimycin A induces G1 arrest through accumulation of p27(Kip1) in cyclin D1-overexpressing fibroblasts.
Biochemical and biophysical research communications.
2000 Jan; 267(1):54-8. doi:
10.1006/bbrc.1999.1927. [PMID: 10623573] - T Ohigashi, M Ueno, S Nonaka, T Nakanoma, Y Furukawa, N Deguchi, M Murai. Tyrosine kinase inhibitors reduce bcl-2 expression and induce apoptosis in androgen-dependent cells.
American journal of physiology. Cell physiology.
2000 Jan; 278(1):C66-72. doi:
10.1152/ajpcell.2000.278.1.c66. [PMID: 10644513] - W Wang, K M Lerea, M Chan, G Giebisch. Protein tyrosine kinase regulates the number of renal secretory K channels.
American journal of physiology. Renal physiology.
2000 Jan; 278(1):F165-71. doi:
10.1152/ajprenal.2000.278.1.f165. [PMID: 10644668] - B A Watts, D W Good. Hyposmolality stimulates apical membrane Na(+)/H(+) exchange and HCO(3)(-) absorption in renal thick ascending limb.
The Journal of clinical investigation.
1999 Dec; 104(11):1593-602. doi:
10.1172/jci7332. [PMID: 10587523] - K D Brubaker, C V Gay. Estrogen stimulates protein tyrosine phosphorylation and Src kinase activity in avian osteoclasts.
Journal of cellular biochemistry.
1999 Dec; 76(2):206-16. doi:
10.1002/(sici)1097-4644(20000201)76:2<206::aid-jcb5>3.3.co;2-i. [PMID: 10618638] - M A Davis, D E Carbott. Herbimycin A and geldanamycin inhibit okadaic acid-induced apoptosis and p38 activation in NRK-52E renal epithelial cells.
Toxicology and applied pharmacology.
1999 Nov; 161(1):59-74. doi:
10.1006/taap.1999.8765. [PMID: 10558924] - X Zhu, C Speth, M P Dierich. Tyrosine phosphorylation of a low molecular weight protein induced by RANTES in T-lymphocytes.
Immunology letters.
1999 Nov; 70(2):101-7. doi:
10.1016/s0165-2478(99)00135-2. [PMID: 10569699] - F Rüdiger, R Greger, R Nitschke, A Henger, P Mundel, H Pavenstädt. Polycations induce calcium signaling in glomerular podocytes.
Kidney international.
1999 Nov; 56(5):1700-9. doi:
10.1046/j.1523-1755.1999.00729.x. [PMID: 10571778] - D English, Y Cui, R Siddiqui, C Patterson, V Natarajan, D N Brindley, J G Garcia. Induction of endothelial monolayer permeability by phosphatidate.
Journal of cellular biochemistry.
1999 Oct; 75(1):105-17. doi:
10.1002/(sici)1097-4644(19991001)75:1<105::aid-jcb11>3.0.co;2-2. [PMID: 10462709] - O S Ruiz, R B Robey, Y Y Qiu, L J Wang, C J Li, J Ma, J A Arruda. Regulation of the renal Na-HCO(3) cotransporter. XI. Signal transduction underlying CO(2) stimulation.
The American journal of physiology.
1999 10; 277(4):F580-6. doi:
10.1152/ajprenal.1999.277.4.f580. [PMID: 10516283] - K Nagaishi, R Adachi, S Matsui, T Yamaguchi, T Kasahara, K Suzuki. Herbimycin A inhibits both dephosphorylation and translocation of cofilin induced by opsonized zymosan in macrophagelike U937 cells.
Journal of cellular physiology.
1999 Sep; 180(3):345-54. doi:
10.1002/(sici)1097-4652(199909)180:3<345::aid-jcp5>3.0.co;2-j. [PMID: 10430174] - J V Jester, J Huang, P A Barry-Lane, W W Kao, W M Petroll, H D Cavanagh. Transforming growth factor(beta)-mediated corneal myofibroblast differentiation requires actin and fibronectin assembly.
Investigative ophthalmology & visual science.
1999 Aug; 40(9):1959-67. doi:
. [PMID: 10440249] - M Bentz, K Harvey, D J Burtschi, D English, R A Siddiqui. Induction of neutrophil calcium mobilization by phosphatidic acid-enriched plasma membranes.
IUBMB life.
1999 Aug; 48(2):179-85. doi:
10.1080/713803499. [PMID: 10794595] - M C Okafor, W L Dean, N A Delamere. Thrombin inhibits active sodium-potassium transport in porcine lens.
Investigative ophthalmology & visual science.
1999 Aug; 40(9):2033-8. doi:
NULL. [PMID: 10440258] - B Y Kim, J H Kim, Y J Han, S C Ahn, D O Kang, W K Oh, H R Ko, H S Lee, T I Mheen, J S Ahn. pp60v-src reactivation inhibits serum-induced accumulation of inositol phosphates and phosphatidylethanol in tsNRK.
IUBMB life.
1999 Jul; 48(1):85-9. doi:
10.1080/713803467. [PMID: 10791920] - S Aono, S Nakagawa, A B Reynolds, M Takeichi. p120(ctn) acts as an inhibitory regulator of cadherin function in colon carcinoma cells.
The Journal of cell biology.
1999 May; 145(3):551-62. doi:
10.1083/jcb.145.3.551. [PMID: 10225956] - D W Good, T George, D H Wang. Angiotensin II inhibits HCO-3 absorption via a cytochrome P-450-dependent pathway in MTAL.
The American journal of physiology.
1999 05; 276(5):F726-36. doi:
10.1152/ajprenal.1999.276.5.f726. [PMID: 10330055] - C A Carter, T Bellido. Decrease in protein tyrosine phosphorylation is associated with F-actin reorganization by retinoic acid in human endometrial adenocarcinoma (RL95-2) cells.
Journal of cellular physiology.
1999 Mar; 178(3):320-32. doi:
10.1002/(sici)1097-4652(199903)178:3<320::aid-jcp6>3.0.co;2-s. [PMID: 9989778] - H O Pae, J C Yoo, B M Choi, S G Paik, Y H Kim, H S Jin, H T Chung. Interferon-gamma alone triggers the production of nitric oxide from serum-starved BNL CL.2, murine embryonic liver cells.
Immunological investigations.
1999 Mar; 28(2-3):149-63. doi:
10.3109/08820139909061144. [PMID: 10484680] - T Zakar, J E Mijovic, D Bhardwaj, D M Olson. Tyrosine kinase inhibitors block the glucocorticoid stimulation of prostaglandin endoperoxide H synthase expression in amnion cells.
Canadian journal of physiology and pharmacology.
1999 Feb; 77(2):138-42. doi:
10.1139/y98-148. [PMID: 10535705] - Z M Dong, L Jackson, J W Murphy. Mechanisms for induction of L-selectin loss from T lymphocytes by a cryptococcal polysaccharide, glucuronoxylomannan.
Infection and immunity.
1999 Jan; 67(1):220-9. doi:
10.1128/iai.67.1.220-229.1999. [PMID: 9864219] - W D Niles, A B Malik. Endocytosis and exocytosis events regulate vesicle traffic in endothelial cells.
The Journal of membrane biology.
1999 Jan; 167(1):85-101. doi:
10.1007/s002329900474. [PMID: 9878078] - Y G Ko, P Liu, R K Pathak, L C Craig, R G Anderson. Early effects of pp60(v-src) kinase activation on caveolae.
Journal of cellular biochemistry.
1998 Dec; 71(4):524-35. doi:
10.1002/(sici)1097-4644(19981215)71:4<524::aid-jcb7>3.0.co;2-b. [PMID: 9827698] - R C Muise-Helmericks, H L Grimes, A Bellacosa, S E Malstrom, P N Tsichlis, N Rosen. Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway.
The Journal of biological chemistry.
1998 Nov; 273(45):29864-72. doi:
10.1074/jbc.273.45.29864. [PMID: 9792703] - Y Murakami, H Fukazawa, S Mizuno, Y Uehara. Effect of herbimycin A on tyrosine kinase receptors and platelet derived growth factor (PDGF)-induced signal transduction.
Biological & pharmaceutical bulletin.
1998 Oct; 21(10):1030-5. doi:
10.1248/bpb.21.1030. [PMID: 9821805] - P T Bozza, W Yu, J Cassara, P F Weller. Pathways for eosinophil lipid body induction: differing signal transduction in cells from normal and hypereosinophilic subjects.
Journal of leukocyte biology.
1998 Oct; 64(4):563-9. doi:
10.1002/jlb.64.4.563. [PMID: 9766638] - M Fujihara, K Ikebuchi, T L Maekawa, S Wakamoto, C Ogiso, T Ito, T A Takahashi, T Suzuki, S Sekiguchi. Lipopolysaccharide-induced desensitization of junB gene expression in a mouse macrophage-like cell line, P388D1.
Journal of immunology (Baltimore, Md. : 1950).
1998 Oct; 161(7):3659-65. doi:
". [PMID: 9759890] - T Hiwasa, Y Nakamura, S Sakiyama. Isolation of a variant which has reduced Src activity from SH-SY5Y neuroblastoma cells.
Anticancer research.
1998 Sep; 18(5A):3311-4. doi:
NULL. [PMID: 9858901] - K Hawks, P J Higgins. Cell shape-dependent pathway of plasminogen activator inhibitor type-1 gene expression requires cytoskeletal reorganization.
Journal of cellular physiology.
1998 Aug; 176(2):293-302. doi:
10.1002/(sici)1097-4652(199808)176:2<293::aid-jcp7>3.0.co;2-j. [PMID: 9648916] - H Tsuganezawa, P A Preisig, R J Alpern. Dominant negative c-Src inhibits angiotensin II induced activation of NHE3 in OKP cells.
Kidney international.
1998 Aug; 54(2):394-8. doi:
10.1046/j.1523-1755.1998.00029.x. [PMID: 9690205] - G Imokawa, Y Yada, N Morisaki, M Kimura. Biological characterization of human fibroblast-derived mitogenic factors for human melanocytes.
The Biochemical journal.
1998 Mar; 330 ( Pt 3)(?):1235-9. doi:
10.1042/bj3301235. [PMID: 9494091] - S Naito, S Shimizu, S Maeda, J Wang, R Paul, J A Fagin. Ets-1 is an early response gene activated by ET-1 and PDGF-BB in vascular smooth muscle cells.
The American journal of physiology.
1998 02; 274(2):C472-80. doi:
10.1152/ajpcell.1998.274.2.c472. [PMID: 9486138] - T van der Bruggen, D Kanters, A T Tool, J A Raaijmakers, J W Lammers, A J Verhoeven, L Koenderman. Cytokine-induced protein tyrosine phosphorylation is essential for cytokine priming of human eosinophils.
The Journal of allergy and clinical immunology.
1998 Jan; 101(1 Pt 1):103-9. doi:
10.1016/s0091-6749(98)70200-3. [PMID: 9449508] - N W Ohan, Y Tam, P Fernando, J J Heikkila. Characterization of a novel group of basic small heat shock proteins in Xenopus laevis A6 kidney epithelial cells.
Biochemistry and cell biology = Biochimie et biologie cellulaire.
1998; 76(4):665-71. doi:
10.1139/bcb-76-4-665. [PMID: 10099789] - M Sato, N Kojima, M Miura, K Imai, H Senoo. Induction of cellular processes containing collagenase and retinoid by integrin-binding to interstitial collagen in hepatic stellate cell culture.
Cell biology international.
1998; 22(2):115-25. doi:
10.1006/cbir.1998.0234. [PMID: 9878098] - F Khechai, V Ollivier, F Bridey, M Amar, J Hakim, D de Prost. Effect of advanced glycation end product-modified albumin on tissue factor expression by monocytes. Role of oxidant stress and protein tyrosine kinase activation.
Arteriosclerosis, thrombosis, and vascular biology.
1997 Nov; 17(11):2885-90. doi:
10.1161/01.atv.17.11.2885. [PMID: 9409271] - P W Tsao, M S Forsythe, S A Mousa. Dissociation between the anti-aggregatory & anti-secretory effects of platelet integrin alpha IIb beta 3 (GPIIb/IIIa) antagonists, c7E3 and DMP728.
Thrombosis research.
1997 Oct; 88(2):137-46. doi:
10.1016/s0049-3848(97)00225-9. [PMID: 9361367] - V Lafont, T Fischer, R Zumbihl, S Faure, C Hivroz, B Rouot, J Favero. Evidence for a CD4-associated calcium influx independent of the phosphoinositide transduction pathway in human T cells.
European journal of immunology.
1997 Sep; 27(9):2261-8. doi:
10.1002/eji.1830270921. [PMID: 9341768] - W M Billis, B A White. Effects of the protein tyrosine kinase inhibitor, herbimycin A, on prolactin gene expression in GH3 and 235-1 pituitary tumor cells.
Biochimica et biophysica acta.
1997 Aug; 1358(1):31-8. doi:
10.1016/s0167-4889(97)00053-0. [PMID: 9296518] - E A Fisher, M Zhou, D M Mitchell, X Wu, S Omura, H Wang, A L Goldberg, H N Ginsberg. The degradation of apolipoprotein B100 is mediated by the ubiquitin-proteasome pathway and involves heat shock protein 70.
The Journal of biological chemistry.
1997 Aug; 272(33):20427-34. doi:
10.1074/jbc.272.33.20427. [PMID: 9252351] - P Buckhaults, L Chen, N Fregien, M Pierce. Transcriptional regulation of N-acetylglucosaminyltransferase V by the src oncogene.
The Journal of biological chemistry.
1997 Aug; 272(31):19575-81. doi:
10.1074/jbc.272.31.19575. [PMID: 9235963] - W N Campbell, M Fitzpatrick, X Ding, M Jett, P Gemski, S E Goldblum. SEB is cytotoxic and alters EC barrier function through protein tyrosine phosphorylation in vitro.
The American journal of physiology.
1997 Jul; 273(1 Pt 1):L31-9. doi:
10.1152/ajplung.1997.273.1.l31. [PMID: 9252537] - D D Bannerman, S E Goldblum. Endotoxin induces endothelial barrier dysfunction through protein tyrosine phosphorylation.
The American journal of physiology.
1997 Jul; 273(1 Pt 1):L217-26. doi:
10.1152/ajplung.1997.273.1.l217. [PMID: 9252559] - H Hagar, N Ueda, S V Shah. Tyrosine phosphorylation in DNA damage and cell death in hypoxic injury to LLC-PK1 cells.
Kidney international.
1997 Jun; 51(6):1747-53. doi:
10.1038/ki.1997.240. [PMID: 9186862] - L Padmore, S An, R H Gunby, K Kelly, G K Radda, K A Knox. CD40-triggered protein tyrosine phosphorylation on Vav and on phosphatidylinositol 3-kinase correlates with survival of the Ramos-Burkitt lymphoma B cell line.
Cellular immunology.
1997 May; 177(2):119-28. doi:
10.1006/cimm.1997.1102. [PMID: 9178638] - T Ogawa, A Ozaki, H Shimauchi, H Uchida. Hyporesponsiveness of inflamed human gingival fibroblasts from patients with chronic periodontal diseases against cell surface components of Porphyromonas gingivalis.
FEMS immunology and medical microbiology.
1997 May; 18(1):17-30. doi:
10.1111/j.1574-695x.1997.tb01023.x. [PMID: 9215583] - P D Prasad, V Torres-Zamorano, R Kekuda, F H Leibach, V Ganapathy. Functional link between tyrosine phosphorylation and human serotonin transporter gene expression.
European journal of pharmacology.
1997 Apr; 325(1):85-92. doi:
10.1016/s0014-2999(97)00100-3. [PMID: 9151943] - S Araki, M Haneda, M Togawa, R Kikkawa. Endothelin-1 activates c-Jun NH2-terminal kinase in mesangial cells.
Kidney international.
1997 Mar; 51(3):631-9. doi:
10.1038/ki.1997.92. [PMID: 9067893] - Y Uehara. [Protein kinase inhibitors--screening of new molecular target therapeutics].
Gan to kagaku ryoho. Cancer & chemotherapy.
1997 Jan; 24(2):136-44. doi:
NULL. [PMID: 9030224] - D Briant, N Ohan, J J Heikkila. Effect of herbimycin A on hsp30 and hsp70 heat shock protein gene expression in Xenopus cultured cells.
Biochemistry and cell biology = Biochimie et biologie cellulaire.
1997; 75(6):777-82. doi:
NULL. [PMID: 9599667]