AIDS-035388 (BioDeep_00000867855)

Main id: BioDeep_00000000851

 

PANOMIX_OTCML-2023


代谢物信息卡片


4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-

化学式: C17H14O7 (330.0739)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=CC(=C2C(=C1)OC(=C(C2=O)OC)C3=CC(=C(C=C3)O)O)O
InChI: InChI=1S/C17H14O7/c1-22-9-6-12(20)14-13(7-9)24-16(17(23-2)15(14)21)8-3-4-10(18)11(19)5-8/h3-7,18-20H,1-2H3

描述信息

同义名列表

19 个代谢物同义名

4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-; 2-(3,4-Dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-chromen-4-one; 2-(3,4-Dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4-benzopyrone; 2-(3,4-dihydroxyphenyl)-5-hydroxy-3,7-dimethoxychromen-4-one; 2-(3,4-dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4-chromenone; 7-O-(omega-substituted)-alkyl-3-O-methyl-quercetin deriv; 2-(3,4-dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-chromone; Flavone, 3,4,5-trihydroxy-3,7-dimethoxy-; 3,7-dimethoxy-5,3,4-trihydroxyflavone; 3,4,5-Trihydroxy-3,7-dimethoxyflavone; 3,7-Di-O-methylquercetin; EINECS 218-187-4; AIDS-035388; CHEBI:18010; AIDS035388; 2068-02-2; C01265; 3,7-Di-O-methylquercetin



数据库引用编号

11 个数据库交叉引用编号

分类词条

24 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 AKT1, EGFR, NQO1, PTGS1, PTGS2, PTPN1, VEGFA
Peripheral membrane protein 4 ACHE, PTGS1, PTGS2, PTPN1
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 5 EGFR, PTGS1, PTGS2, PTPN1, RAC2
Nucleus 5 ACHE, AKT1, EGFR, NQO1, VEGFA
cytosol 4 AKT1, NQO1, PTPN1, RAC2
dendrite 1 NQO1
nucleoplasm 1 AKT1
Cell membrane 4 ACHE, AKT1, EGFR, TNF
Cytoplasmic side 1 PTPN1
lamellipodium 2 AKT1, RAC2
ruffle membrane 1 EGFR
Early endosome membrane 1 EGFR
Synapse 2 ACHE, NQO1
cell cortex 1 AKT1
cell junction 1 EGFR
cell surface 4 ACHE, EGFR, TNF, VEGFA
glutamatergic synapse 3 AKT1, EGFR, PTPN1
Golgi apparatus 3 ACHE, PTGS1, VEGFA
Golgi membrane 1 EGFR
lysosomal membrane 1 GAA
neuromuscular junction 1 ACHE
neuronal cell body 2 NQO1, TNF
postsynapse 2 AKT1, PTPN1
Cytoplasm, cytosol 1 NQO1
Lysosome 1 GAA
endosome 1 EGFR
plasma membrane 6 ACHE, AKT1, EGFR, GAA, RAC2, TNF
Membrane 7 ACHE, AKT1, EGFR, GAA, NQO1, PTPN1, VEGFA
apical plasma membrane 1 EGFR
basolateral plasma membrane 1 EGFR
caveola 1 PTGS2
extracellular exosome 4 GAA, MMP9, PTGS1, RAC2
Lysosome membrane 1 GAA
endoplasmic reticulum 3 PTGS2, PTPN1, VEGFA
extracellular space 5 ACHE, EGFR, MMP9, TNF, VEGFA
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 2 ACHE, EGFR
adherens junction 1 VEGFA
protein-containing complex 4 AKT1, EGFR, PTGS2, PTPN1
intracellular membrane-bounded organelle 2 GAA, PTGS1
Microsome membrane 2 PTGS1, PTGS2
Single-pass type I membrane protein 1 EGFR
Secreted 3 ACHE, GAA, VEGFA
extracellular region 5 ACHE, GAA, MMP9, TNF, VEGFA
mitochondrial outer membrane 1 RAC2
mitochondrial matrix 1 PTPN1
Extracellular side 1 ACHE
photoreceptor outer segment 1 PTGS1
nuclear membrane 1 EGFR
external side of plasma membrane 1 TNF
Secreted, extracellular space, extracellular matrix 2 MMP9, VEGFA
microtubule cytoskeleton 1 AKT1
Early endosome 1 PTPN1
cell-cell junction 1 AKT1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
Membrane raft 2 EGFR, TNF
focal adhesion 2 EGFR, RAC2
spindle 1 AKT1
extracellular matrix 1 VEGFA
basement membrane 1 ACHE
intracellular vesicle 1 EGFR
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
collagen-containing extracellular matrix 1 MMP9
secretory granule 1 VEGFA
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
receptor complex 1 EGFR
neuron projection 2 PTGS1, PTGS2
ciliary basal body 1 AKT1
phagocytic cup 1 TNF
phagocytic vesicle membrane 1 RAC2
mitochondrial crista 1 PTPN1
Lipid-anchor, GPI-anchor 1 ACHE
nuclear envelope 1 RAC2
Endomembrane system 2 PTGS1, PTPN1
endosome lumen 1 PTPN1
sorting endosome 1 PTPN1
tertiary granule membrane 1 GAA
side of membrane 1 ACHE
basal plasma membrane 1 EGFR
synaptic membrane 1 EGFR
ficolin-1-rich granule lumen 1 MMP9
endoplasmic reticulum lumen 1 PTGS2
platelet alpha granule lumen 1 VEGFA
tertiary granule lumen 1 MMP9
azurophil granule membrane 1 GAA
clathrin-coated endocytic vesicle membrane 1 EGFR
synaptic cleft 1 ACHE
ficolin-1-rich granule membrane 1 GAA
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
NADPH oxidase complex 1 RAC2
autolysosome lumen 1 GAA
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
cytoplasmic side of endoplasmic reticulum membrane 1 PTPN1
[Isoform H]: Cell membrane 1 ACHE
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Marita Vu, Lars Herfindal, Ole Johan Juvik, Anni Vedeler, Svein Haavik, Torgils Fossen. Toxic aromatic compounds from fruits of Narthecium ossifragum L. Phytochemistry. 2016 Dec; 132(?):76-85. doi: 10.1016/j.phytochem.2016.09.010. [PMID: 27720435]
  • Eva Kranjc, Alen Albreht, Irena Vovk, Damjan Makuc, Janez Plavec. Non-targeted chromatographic analyses of cuticular wax flavonoids from Physalis alkekengi L. Journal of chromatography. A. 2016 Mar; 1437(?):95-106. doi: 10.1016/j.chroma.2016.01.061. [PMID: 26875116]
  • Ying-Kun Qiu, Ting-Guo Kang, De-Qiang Dou, Li Liang, Feng Dong. Three novel compounds from the leaves of Smallanthus sonchifolius. Journal of Asian natural products research. 2008 Nov; 10(11-12):1109-15. doi: 10.1080/10286020802361230. [PMID: 19031255]
  • Li-Min Dai, Chun-Chao Zhao, Hui-zi Jin, Jian Tang, Yun-Heng Shen, Hui-Liang Li, Cai-Yun Peng, Wei-Dong Zhang. A new ferulic acid ester and other constituents from Dracocephalum peregrinum. Archives of pharmacal research. 2008 Oct; 31(10):1325-9. doi: 10.1007/s12272-001-2113-2. [PMID: 18958424]
  • Esra Küpeli, Erdem Yesilada. Flavonoids with anti-inflammatory and antinociceptive activity from Cistus laurifolius L. leaves through bioassay-guided procedures. Journal of ethnopharmacology. 2007 Jul; 112(3):524-30. doi: 10.1016/j.jep.2007.04.011. [PMID: 17540523]
  • Samir Kumar Sadhu, Emi Okuyama, Haruhiro Fujimoto, Masami Ishibashi, Erdem Yesilada. Prostaglandin inhibitory and antioxidant components of Cistus laurifolius, a Turkish medicinal plant. Journal of ethnopharmacology. 2006 Dec; 108(3):371-8. doi: 10.1016/j.jep.2006.05.024. [PMID: 16814498]
  • Esra Küpeli, Didem Deliorman Orhan, Erdem Yesilada. Effect of Cistus laurifolius L. leaf extracts and flavonoids on acetaminophen-induced hepatotoxicity in mice. Journal of ethnopharmacology. 2006 Feb; 103(3):455-60. doi: 10.1016/j.jep.2005.08.038. [PMID: 16216454]
  • Naoto Osaki, Takashi Koyano, Thaworn Kowithayakorn, Masahiko Hayashi, Kanki Komiyama, Masami Ishibashi. Sesquiterpenoids and plasmin-inhibitory flavonoids from Blumea balsamifera. Journal of natural products. 2005 Mar; 68(3):447-9. doi: 10.1021/np049622e. [PMID: 15787457]
  • Pilar Puebla, Jose L López, Mario Guerrero, Rosalía Carrón, M Luisa Martín, Luis San Román, Arturo San Feliciano. Neo-clerodane diterpenoids from Croton schiedeanus. Phytochemistry. 2003 Feb; 62(4):551-5. doi: 10.1016/s0031-9422(02)00516-2. [PMID: 12560024]
  • M F Guerrero, P Puebla, R Carrón, M L Martín, L San Román. Quercetin 3,7-dimethyl ether: a vasorelaxant flavonoid isolated from Croton schiedeanus Schlecht. The Journal of pharmacy and pharmacology. 2002 Oct; 54(10):1373-8. doi: 10.1211/002235702760345455. [PMID: 12396299]
  • X P Dong, C T Che, N R Farnsworth. Cytotoxic flavonols from Gutierrezia microcephala. Journal of natural products. 1987 Mar; 50(2):337-8. doi: 10.1021/np50050a065. [PMID: 3655803]