4-Hydroxy-3-methoxybenzenemethanol (BioDeep_00000000865)

 

Secondary id: BioDeep_00000419612, BioDeep_00000861607

human metabolite PANOMIX_OTCML-2023 Endogenous Chemicals and Drugs


代谢物信息卡片


2-Pyridinecarboxylicacid, 6-amino-3-bromo-, methyl ester

化学式: C8H10O3 (154.063)
中文名称: 4-羟基-3-甲氧基苯甲醇, 4-羟基-3-甲氧基苄醇
谱图信息: 最多检出来源 Homo sapiens(plant) 9.41%

分子结构信息

SMILES: COC1=C(C=CC(=C1)CO)O
InChI: InChI=1S/C8H10O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-4,9-10H,5H2,1H3

描述信息

4-Hydroxy-3-methoxybenzenemethanol, also known as 4-hydroxy-3-methoxybenzyl alcohol or 3-methoxy-4-hydroxybenzyl alcohol, belongs to the class of organic compounds known as methoxyphenols. Methoxyphenols are compounds containing a methoxy group attached to the benzene ring of a phenol moiety. 4-Hydroxy-3-methoxybenzenemethanol is a drug. 4-Hydroxy-3-methoxybenzenemethanol is a sweet, anise, and balsam tasting compound. 4-hydroxy-3-methoxybenzenemethanol has been detected, but not quantified, in fruits and herbs and spices. This could make 4-hydroxy-3-methoxybenzenemethanol a potential biomarker for the consumption of these foods.
Vanillyl alcohol is a monomethoxybenzene that is 2-methoxyphenol substituted by a hydroxymethyl group at position 4. It has a role as a plant metabolite. It is a member of guaiacols and a member of benzyl alcohols.
Vanillyl alcohol has been used in trials studying the treatment of Smoking.
Vanillyl alcohol is a natural product found in Artemisia rutifolia, Euglena gracilis, and other organisms with data available.
Constituent of Capsicum subspecies; flavouring ingredient. 4-Hydroxy-3-methoxybenzenemethanol is found in herbs and spices and fruits.
A monomethoxybenzene that is 2-methoxyphenol substituted by a hydroxymethyl group at position 4.
Vanillyl alcohol (p-(Hydroxymethyl)guaiacol), derived from vanillin, is a phenolic alcohol and is used as a flavoring agent in foods and beverages[1].
Vanillyl alcohol (p-(Hydroxymethyl)guaiacol), derived from vanillin, is a phenolic alcohol and is used as a flavoring agent in foods and beverages[1].

同义名列表

37 个代谢物同义名

2-Pyridinecarboxylicacid, 6-amino-3-bromo-, methyl ester; 4-(hydroxymethyl)-2-methoxy-phenol;Vanillyl Alcohol; 4-HYDROXY-3-METHOXYBENZYLALCOHOL(VANILLICALCOHOL); 4-Hydroxy-3-methoxybenzenemethanol, 9CI; 4-Hydroxy-3-methoxybenzyl alcohol, 98\\%; Vanillyl alcohol, analytical standard; Benzenemethanol, 4-hydroxy-3-methoxy-; 4-(Hydroxymethyl)-2-methoxyphenol #; 4-Hydroxy-3-methoxy-benzenemethanol; 4-HYDROXY-3-METHOXY-BENZYL ALCOHOL; 4-Hydroxy-3-methoxybenzenemethanol; 4-Hydroxy-3-methoxyphenyl methanol; 4-(hydroxymethyl)-2-methoxy-phenol; 4-(Hydroxymethyl)-2-methoxyphenol; 4-hidroxy-3-methoxybenzyl alcohol; 4-Hydroxy-3-methoxyphenylmethanol; 3-Methoxy-4-hydroxybenzyl alcohol; 4-Hydroxy-3-methoxybenzyl alcohol; 4-Hydroxy-3-methyl benzyl alcohol; 4-hydroxymethyl-2-methoxyphenol; a,4-Dihydroxy-3-methoxytoluene; Vanillyl alcohol, >=98\\%, FG; VANILLYL ALCOHOL [FHFI]; Vanillic alcohol; Vanillyl alcohol; Vanillin alcohol; V 0018 (Alcohol); VANILLYL-ALCOHOL; UNII-X7EA1JUA6M; vanillylalcohol; Oprea1_448599; X7EA1JUA6M; AI3-24186; FEMA 3737; vanillol; p-(Hydroxymethyl)guaiacol; Vanillyl alcohol



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

16 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ANG, BCL2, CASP3, CAT, EDN1, PFDN5, PLA2G12A, VEGFA
Peripheral membrane protein 1 CYP1B1
Endoplasmic reticulum membrane 2 BCL2, CYP1B1
Nucleus 6 ANG, BCL2, CASP3, PARP1, PFDN5, VEGFA
cytosol 12 ACOX1, ADH6, AKR1A1, ANG, BCL2, CASP3, CAT, IL1B, LIPE, PARP1, PFDN5, PRKCQ
nuclear body 1 PARP1
nucleoplasm 2 CASP3, PARP1
Cell membrane 4 CDON, LIPE, PECAM1, TBXA2R
Multi-pass membrane protein 1 TBXA2R
Synapse 1 AKR1A1
cell junction 1 PECAM1
cell surface 1 VEGFA
glutamatergic synapse 1 CASP3
Golgi apparatus 1 VEGFA
growth cone 1 ANG
neuronal cell body 2 ANG, CASP3
Cytoplasm, cytosol 4 AKR1A1, IL1B, LIPE, PARP1
Lysosome 1 IL1B
acrosomal vesicle 1 TBXA2R
plasma membrane 5 BTC, CDON, PECAM1, PRKCQ, TBXA2R
Membrane 9 ACOX1, BCL2, BTC, CAT, CDON, CYP1B1, LIPE, PARP1, VEGFA
apical plasma membrane 1 AKR1A1
caveola 1 LIPE
extracellular exosome 4 ADH6, AKR1A1, CAT, PECAM1
endoplasmic reticulum 2 BCL2, VEGFA
extracellular space 7 AKR1A1, ANG, BTC, EDN1, IL1B, PECAM1, VEGFA
adherens junction 1 VEGFA
mitochondrion 4 BCL2, CAT, CYP1B1, PARP1
protein-containing complex 4 BCL2, CAT, PARP1, PECAM1
intracellular membrane-bounded organelle 2 CAT, CYP1B1
Microsome membrane 1 CYP1B1
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 PECAM1
Secreted 5 ANG, EDN1, IL1B, PLA2G12A, VEGFA
extracellular region 7 ANG, BTC, CAT, EDN1, IL1B, PLA2G12A, VEGFA
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 2 BCL2, CDON
mitochondrial outer membrane 1 BCL2
basal part of cell 1 EDN1
mitochondrial matrix 1 CAT
transcription regulator complex 1 PARP1
centriolar satellite 1 PRKCQ
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 PECAM1
Secreted, extracellular space, extracellular matrix 1 VEGFA
actin cytoskeleton 1 ANG
nucleolus 2 ANG, PARP1
cell-cell junction 1 PECAM1
Apical cell membrane 1 AKR1A1
Membrane raft 1 PECAM1
pore complex 1 BCL2
focal adhesion 1 CAT
extracellular matrix 1 VEGFA
Peroxisome 2 ACOX1, CAT
basement membrane 1 ANG
Peroxisome matrix 1 CAT
peroxisomal matrix 2 ACOX1, CAT
peroxisomal membrane 2 ACOX1, CAT
secretory granule 2 IL1B, VEGFA
nuclear speck 1 TBXA2R
chromatin 1 PARP1
Chromosome 2 ANG, PARP1
Nucleus, nucleolus 2 ANG, PARP1
nuclear replication fork 1 PARP1
chromosome, telomeric region 1 PARP1
site of double-strand break 1 PARP1
nuclear envelope 1 PARP1
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
Cytoplasm, Stress granule 1 ANG
cytoplasmic stress granule 1 ANG
myelin sheath 1 BCL2
intermediate filament cytoskeleton 1 PFDN5
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
secretory granule membrane 1 PECAM1
platelet alpha granule lumen 1 VEGFA
endocytic vesicle 1 ANG
transport vesicle 1 EDN1
Secreted, extracellular exosome 1 IL1B
immunological synapse 1 PRKCQ
aggresome 1 PRKCQ
clathrin-coated endocytic vesicle membrane 1 BTC
prefoldin complex 1 PFDN5
protein-DNA complex 1 PARP1
death-inducing signaling complex 1 CASP3
[Isoform Long]: Cell membrane 1 PECAM1
platelet alpha granule membrane 1 PECAM1
site of DNA damage 1 PARP1
angiogenin-PRI complex 1 ANG
rough endoplasmic reticulum lumen 1 EDN1
catalase complex 1 CAT
Weibel-Palade body 1 EDN1
[Poly [ADP-ribose] polymerase 1, processed N-terminus]: Chromosome 1 PARP1
[Poly [ADP-ribose] polymerase 1, processed C-terminus]: Cytoplasm 1 PARP1
BAD-BCL-2 complex 1 BCL2
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
[Isoform Delta15]: Cell junction 1 PECAM1


文献列表

  • Yousun Lee, Sujin Lee, Sungjun Kim, Dogyeong Lee, Keehoon Won. Solvent-free enzymatic synthesis and evaluation of vanillyl propionate as an effective and biocompatible preservative. Bioprocess and biosystems engineering. 2023 Sep; ?(?):. doi: 10.1007/s00449-023-02921-1. [PMID: 37682355]
  • Ruijian Li, Sang Jae Rhee, Soochan Bae, Shi Su, Chang-Sun Kang, Qingen Ke, Ye Eun Koo, Chloe Ryu, Chul Gyu Song, Dongwon Lee, Peter M Kang. H2O2-Responsive Antioxidant Nanoparticle Attenuates Whole Body Ischemia/Reperfusion-Induced Multi-Organ Damages. Journal of cardiovascular pharmacology and therapeutics. 2021 05; 26(3):279-288. doi: 10.1177/1074248420969571. [PMID: 33111565]
  • Yoshiyuki Tanaka, Takaya Asano, Yorika Kanemitsu, Tanjuro Goto, Yuichi Yoshida, Kenichiro Yasuba, Yuki Misawa, Sachie Nakatani, Kenji Kobata. Positional differences of intronic transposons in pAMT affect the pungency level in chili pepper through altered splicing efficiency. The Plant journal : for cell and molecular biology. 2019 11; 100(4):693-705. doi: 10.1111/tpj.14462. [PMID: 31323150]
  • Juan Antonio Méndez-Líter, Isabel Tundidor, Manuel Nieto-Domínguez, Beatriz Fernández de Toro, Andrés González Santana, Laura Isabel de Eugenio, Alicia Prieto, Juan Luis Asensio, Francisco Javier Cañada, Cristina Sánchez, María Jesús Martínez. Transglycosylation products generated by Talaromyces amestolkiae GH3 β-glucosidases: effect of hydroxytyrosol, vanillin and its glucosides on breast cancer cells. Microbial cell factories. 2019 May; 18(1):97. doi: 10.1186/s12934-019-1147-4. [PMID: 31151435]
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  • Daisuke Sato, Yuki Eshita, Hisashi Katsuragi, Hiroki Hamada, Kei Shimoda, Naoji Kubota. Glycosylation of vanillin and 8-nordihydrocapsaicin by cultured Eucalyptus perriniana cells. Molecules (Basel, Switzerland). 2012 May; 17(5):5013-20. doi: 10.3390/molecules17055013. [PMID: 22552154]
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