30373-88-7 (BioDeep_00000861709)

Main id: BioDeep_00000003666

 

PANOMIX_OTCML-2023


代谢物信息卡片


3-[[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxy]-2-tetrahydropyranyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-chromenone

化学式: C27H30O16 (610.1534)
中文名称: 山奈酚-3-O-β-D-槐糖苷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)OC5C(C(C(C(O5)CO)O)O)O)O
InChI: InChI=1S/C27H30O16/c28-7-14-17(33)20(36)22(38)26(40-14)43-25-21(37)18(34)15(8-29)41-27(25)42-24-19(35)16-12(32)5-11(31)6-13(16)39-23(24)9-1-3-10(30)4-2-9/h1-6,14-15,17-18,20-22,25-34,36-38H,7-8H2/t14-,15-,17-,18-,20+,21+,22-,25-,26+,27+/m1/s1

描述信息

Kaempferol 3-O-sophoroside, a derivative of Kaempferol, is isolated from the leaves of cultivated mountain ginseng (Panax ginseng) with anti-inflammatory effects[1].
Kaempferol 3-O-sophoroside, a derivative of Kaempferol, is isolated from the leaves of cultivated mountain ginseng (Panax ginseng) with anti-inflammatory effects[1].

同义名列表

19 个代谢物同义名

3-[[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxy]-2-tetrahydropyranyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-chromenone; 3-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]oxy-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one; 3-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-methylol-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]oxy-5,7-dihydroxy-2-(4-hydroxyphenyl)chromone; 3-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-oxan-2-yl]oxy-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one; 3-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one; 4H-1-Benzopyran-4-one, 3-((2-O-beta-D-glucopyranosyl-beta-diglucopyranosyl)oxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-; 4H-1-Benzopyran-4-one, 3-((2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-; Flavone, 3,4,5,7-tetrahydroxy-, 3-(2-O-beta-D-glucopyranosyl-beta-glucopyranoside); Kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside; Kaempferol 3-O-beta-D-sophoroside; Kaempferol-3-O-sophoroside; kaempferol 3-O-sophoroside; Kaempferol-3-sophoroside; Sophoraflavonoloside; 30373-88-7; 19895-95-5; C12634; K3S; Kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(3)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

66 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 BCL2, BDNF, CASP3, CASP9, CAT, HMGB1, KEAP1, PTGS1, SOD1, VEGFA
Peripheral membrane protein 3 GBA1, HMGB1, PTGS1
Endoplasmic reticulum membrane 3 BCL2, HMOX1, PTGS1
Nucleus 9 BCL2, CASP3, CASP9, GABPA, HMGB1, HMOX1, KEAP1, SOD1, VEGFA
cytosol 7 BCL2, CASP3, CASP9, CAT, HMOX1, KEAP1, SOD1
dendrite 1 BDNF
trans-Golgi network 1 GBA1
nucleoplasm 6 CASP3, GABPA, HMGB1, HMOX1, KEAP1, SOD1
Cell membrane 2 HMGB1, TNF
Cytoplasmic side 1 HMOX1
cell junction 1 AGER
cell surface 4 AGER, HMGB1, TNF, VEGFA
glutamatergic synapse 1 CASP3
Golgi apparatus 3 GBA1, PTGS1, VEGFA
lysosomal membrane 2 GAA, GBA1
neuronal cell body 3 CASP3, SOD1, TNF
postsynapse 1 AGER
synaptic vesicle 1 BDNF
Lysosome 2 GAA, GBA1
endosome 1 HMGB1
plasma membrane 4 AGER, GAA, HMGB1, TNF
Membrane 7 AGER, BCL2, BDNF, CAT, GAA, HMOX1, VEGFA
apical plasma membrane 1 AGER
axon 1 BDNF
extracellular exosome 5 CAT, GAA, GBA1, PTGS1, SOD1
Lysosome membrane 2 GAA, GBA1
Lumenal side 1 GBA1
endoplasmic reticulum 6 BCL2, GBA1, HMGB1, HMOX1, KEAP1, VEGFA
extracellular space 10 BDNF, CXCL8, HMGB1, HMOX1, IL10, IL6, PNLIP, SOD1, TNF, VEGFA
lysosomal lumen 2 GAA, GBA1
perinuclear region of cytoplasm 2 BDNF, HMOX1
adherens junction 1 VEGFA
mitochondrion 4 BCL2, CASP9, CAT, SOD1
protein-containing complex 4 BCL2, CASP9, CAT, SOD1
intracellular membrane-bounded organelle 3 CAT, GAA, PTGS1
Microsome membrane 1 PTGS1
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 AGER
Secreted 8 BDNF, CXCL8, GAA, HMGB1, IL10, IL6, PNLIP, VEGFA
extracellular region 12 AGER, BDNF, CAT, CXCL8, GAA, HMGB1, IL10, IL6, PNLIP, SOD1, TNF, VEGFA
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, HMOX1
mitochondrial matrix 2 CAT, SOD1
Extracellular side 1 HMGB1
centriolar satellite 1 KEAP1
photoreceptor outer segment 1 PTGS1
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 TNF
Secreted, extracellular space, extracellular matrix 1 VEGFA
cytoplasmic vesicle 1 SOD1
axon cytoplasm 1 SOD1
midbody 1 KEAP1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 1 TNF
pore complex 1 BCL2
focal adhesion 1 CAT
extracellular matrix 1 VEGFA
Peroxisome 2 CAT, SOD1
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
mitochondrial intermembrane space 1 SOD1
secretory granule 1 VEGFA
dendrite cytoplasm 1 SOD1
neuron projection 1 PTGS1
chromatin 1 GABPA
phagocytic cup 1 TNF
Chromosome 1 HMGB1
actin filament 1 KEAP1
Cul3-RING ubiquitin ligase complex 1 KEAP1
fibrillar center 1 AGER
Endomembrane system 1 PTGS1
tertiary granule membrane 1 GAA
myelin sheath 1 BCL2
ficolin-1-rich granule lumen 2 CAT, HMGB1
secretory granule lumen 2 CAT, HMGB1
endoplasmic reticulum lumen 2 BDNF, IL6
transcription repressor complex 1 HMGB1
platelet alpha granule lumen 1 VEGFA
azurophil granule membrane 1 GAA
Single-pass type IV membrane protein 1 HMOX1
apoptosome 1 CASP9
endoplasmic reticulum-Golgi intermediate compartment 1 HMGB1
ficolin-1-rich granule membrane 1 GAA
death-inducing signaling complex 1 CASP3
[Isoform 1]: Cell membrane 1 AGER
condensed chromosome 1 HMGB1
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
inclusion body 1 KEAP1
alphav-beta3 integrin-HMGB1 complex 1 HMGB1
interleukin-6 receptor complex 1 IL6
autolysosome lumen 1 GAA
BAD-BCL-2 complex 1 BCL2
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
caspase complex 1 CASP9
[Isoform 10]: Cell membrane 1 AGER
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Javad Mottaghipisheh, Mohammad Mahmoodi Sourestani, Tivadar Kiss, Attila Horváth, Barbara Tóth, Mehdi Ayanmanesh, Amin Khamushi, Dezső Csupor. Comprehensive chemotaxonomic analysis of saffron crocus tepal and stamen samples, as raw materials with potential antidepressant activity. Journal of pharmaceutical and biomedical analysis. 2020 May; 184(?):113183. doi: 10.1016/j.jpba.2020.113183. [PMID: 32105944]
  • Christoph Hald, Corinna Dawid, Ralf Tressel, Thomas Hofmann. Kaempferol 3- O-(2‴- O-Sinapoyl-β-sophoroside) Causes the Undesired Bitter Taste of Canola/Rapeseed Protein Isolates. Journal of agricultural and food chemistry. 2019 Jan; 67(1):372-378. doi: 10.1021/acs.jafc.8b06260. [PMID: 30525566]
  • Pham Thi Nhat Trinh, Nguyen Huu An, Pham Ngoc An, Mai Dinh Tri, Cao Van Du, Phan Nhat Minh, Nguyen Thi Le Thuy, Nguyen Trong Tuan, Vang Thi Kim Thoa, Nguyen Ngoc Tuan, Le Tien Dung. A new benzofuran derivative from the leaves of Ficus pumila L. Natural product research. 2018 Jul; 32(14):1648-1652. doi: 10.1080/14786419.2017.1395427. [PMID: 29072969]
  • Sheela Verjee, Eliane Garo, Sarah Pelaez, Orlando Fertig, Matthias Hamburger, Veronika Butterweck. Saffron Flower Extract Promotes Scratch Wound Closure of Keratinocytes and Enhances VEGF Production. Planta medica. 2017 Oct; 83(14-15):1176-1183. doi: 10.1055/s-0043-109002. [PMID: 28427103]
  • Sanawar Mansur, Rahima Abdulla, Amatjan Ayupbec, Haji Akbar Aisa. Chemical Fingerprint Analysis and Quantitative Analysis of Rosa rugosa by UPLC-DAD. Molecules (Basel, Switzerland). 2016 Dec; 21(12):. doi: 10.3390/molecules21121754. [PMID: 28009848]
  • Almudena Trapero, Oussama Ahrazem, Angela Rubio-Moraga, Maria Luisa Jimeno, Maria Dolores Gómez, Lourdes Gómez-Gómez. Characterization of a glucosyltransferase enzyme involved in the formation of kaempferol and quercetin sophorosides in Crocus sativus. Plant physiology. 2012 Aug; 159(4):1335-54. doi: 10.1104/pp.112.198069. [PMID: 22649274]
  • Tae Hoon Kim, Sae-Kwang Ku, In-Chul Lee, Jong-Sup Bae. Anti-inflammatory effects of kaempferol-3-O-sophoroside in human endothelial cells. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 2012 Mar; 61(3):217-24. doi: 10.1007/s00011-011-0403-9. [PMID: 22113342]
  • Willibald Schliemann, Bernd Schneider, Victor Wray, Jürgen Schmidt, Manfred Nimtz, Andrea Porzel, Hartmut Böhm. Flavonols and an indole alkaloid skeleton bearing identical acylated glycosidic groups from yellow petals of Papaver nudicaule. Phytochemistry. 2006 Jan; 67(2):191-201. doi: 10.1016/j.phytochem.2005.11.002. [PMID: 16376394]
  • S Palanichamy, S Nagarajan. Analgesic activity of Cassia alata leaf extract and kaempferol 3-o-sophoroside. Journal of ethnopharmacology. 1990 Apr; 29(1):73-8. doi: 10.1016/0378-8741(90)90099-f. [PMID: 2345462]