octacosanol (BioDeep_00000859789)

Main id: BioDeep_00000000529

 

PANOMIX_OTCML-2023


代谢物信息卡片


Octacosyl alcohol

化学式: C28H58O (410.4487418)
中文名称: 二十八烷醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCCCCCCCCCCCCCCCCCCCCCCCCO
InChI: InChI=1S/C28H58O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-27-28-29/h29H,2-28H2,1H3

描述信息

同义名列表

17 个代谢物同义名

Octacosyl alcohol; EINECS 209-181-2; Montanyl alcohol; Cluytyl alcohol; Octacosan-1-ol; OCTACOSANOL-1; 1-Octacosanol; n-octacosanol; LMFA05000003; octacosanol; CHEBI:28243; O3379_SIGMA; NSC 10770; 557-61-9; NSC10770; NSC57768; C08387



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

93 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yin-Yi Ding, Yumeng Fang, Yuxiang Pan, Jinchi Lan, Tao Xu, Wanyue Zhang, Huijuan Mao, Zhenyu Gu, Xi Chen, Qing Shen. Orally administered octacosanol improves liver insulin resistance in high-fat diet-fed mice through the reconstruction of the gut microbiota structure and inhibition of the TLR4/NF-κB inflammatory pathway. Food & function. 2023 Jan; 14(2):769-786. doi: 10.1039/d2fo02463b. [PMID: 36594412]
  • Khalid Bashir Dar, Ruhban Ansar Parry, Aashiq Hussain Bhat, Afaq Hameed Beigh, Maroof Ahmed, Umer Majeed Khaja, Aijaz Hassan Ganie, Manzoor Ahmad Mir, Bilal Ahmad Reshi, Ishfaq Shafi Khan, Showkat Ahmad Ganie. Immunomodulatory efficacy of Cousinia thomsonii C.B. Clarke in ameliorating inflammatory cascade expressions. Journal of ethnopharmacology. 2023 Jan; 300(?):115727. doi: 10.1016/j.jep.2022.115727. [PMID: 36116611]
  • Milica Zrnic Ciric, Miodrag Ostojic, Ivana Baralic, Jelena Kotur-Stevuljevic, Brizita I Djordjevic, Stana Markovic, Stefan Zivkovic, Ivan Stankovic. Supplementation with Octacosanol Affects the Level of PCSK9 and Restore Its Physiologic Relation with LDL-C in Patients on Chronic Statin Therapy. Nutrients. 2021 Mar; 13(3):. doi: 10.3390/nu13030903. [PMID: 33802219]
  • Mirka Macel, Isabella G S Visschers, Janny L Peters, Nicole M van Dam, Rob M de Graaf. High Concentrations of Very Long Chain Leaf Wax Alkanes of Thrips Susceptible Pepper Accessions (Capsicum spp). Journal of chemical ecology. 2020 Dec; 46(11-12):1082-1089. doi: 10.1007/s10886-020-01226-x. [PMID: 33089351]
  • Ji-Eun Ra, So-Yeun Woo, Kwang-Sik Lee, Mi Ja Lee, Hyun Young Kim, Hyeon Mi Ham, Ill-Min Chung, Du Hyun Kim, Jin Hwan Lee, Woo Duck Seo. Policosanol profiles and adenosine 5'-monophosphate-activated protein kinase (AMPK) activation potential of Korean wheat seedling extracts according to cultivar and growth time. Food chemistry. 2020 Jul; 317(?):126388. doi: 10.1016/j.foodchem.2020.126388. [PMID: 32078993]
  • Rahul Sharma, Takashi Matsuzaka, Mahesh K Kaushik, Takehito Sugasawa, Hiroshi Ohno, Yunong Wang, Kaori Motomura, Takuya Shimura, Yuka Okajima, Yuhei Mizunoe, Yang Ma, Zahara M Saber, Hitoshi Iwasaki, Shigeru Yatoh, Hiroaki Suzuki, Yuichi Aita, Song-Iee Han, Yoshinori Takeuchi, Naoya Yahagi, Takafumi Miyamoto, Motohiro Sekiya, Yoshimi Nakagawa, Hitoshi Shimano. Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism. Scientific reports. 2019 03; 9(1):5169. doi: 10.1038/s41598-019-41631-1. [PMID: 30914769]
  • Yang-Hee Cho, Rozbeh Farhoudi, Muhammad Farooq, Dong-Jin Lee. Evaluating Korean rice genotypes and landraces for octacosanol contents and antioxidant activity. Natural product research. 2017 Dec; 31(23):2778-2782. doi: 10.1080/14786419.2017.1292271. [PMID: 28278625]
  • Surashree Sen Gupta, Mahua Ghosh. Octacosanol educes physico-chemical attributes, release and bioavailability as modified nanocrystals. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2017 Oct; 119(?):201-214. doi: 10.1016/j.ejpb.2017.06.020. [PMID: 28648862]
  • Mahesh K Kaushik, Kosuke Aritake, Atsuko Takeuchi, Masashi Yanagisawa, Yoshihiro Urade. Octacosanol restores stress-affected sleep in mice by alleviating stress. Scientific reports. 2017 08; 7(1):8892. doi: 10.1038/s41598-017-08874-2. [PMID: 28827687]
  • Tianyi Guo, Qinlu Lin, Xinhua Li, Ying Nie, Long Wang, Limin Shi, Wei Xu, Tao Hu, Ting Guo, Feijun Luo. Octacosanol Attenuates Inflammation in Both RAW264.7 Macrophages and a Mouse Model of Colitis. Journal of agricultural and food chemistry. 2017 May; 65(18):3647-3658. doi: 10.1021/acs.jafc.6b05465. [PMID: 28122452]
  • L Long, S G Wu, F Yuan, H J Zhang, J Wang, G H Qi. Effects of dietary octacosanol supplementation on laying performance, egg quality, serum hormone levels, and expression of genes related to the reproductive axis in laying hens. Poultry science. 2017 Apr; 96(4):894-903. doi: 10.3382/ps/pew316. [PMID: 27665009]
  • Yu-Wei Liu, Pei-Yuan Zuo, Xiang-Nan Zha, Xing-Lin Chen, Rong Zhang, Xiao-Xiao He, Cheng-Yun Liu. Octacosanol enhances the proliferation and migration of human umbilical vein endothelial cells via activation of the PI3K/Akt and MAPK/Erk pathways. Lipids. 2015 Mar; 50(3):241-51. doi: 10.1007/s11745-015-3991-2. [PMID: 25638063]
  • Angelo Maria Giuffrè, Marco Capocasale. Policosanol in Tomato (Solanum lycopersicum L.) Seed Oil: the Effect of Cultivar. Journal of oleo science. 2015; 64(6):625-31. doi: 10.5650/jos.ess15002. [PMID: 25891114]
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