Antioxine (BioDeep_00000859508)
Main id: BioDeep_00000000780
PANOMIX_OTCML-2023 Antitumor activity
代谢物信息卡片
化学式: C10H14O (150.1045)
中文名称: 香芹酚
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C=C(C=C1)C(C)C)O
InChI: InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4-7,11H,1-3H3
描述信息
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
Carvacrol is a monoterpenoid phenol isolated from Thymus mongolicus Ronn., with antioxidant, anti-inflammatory and anticancer properties. Carvacrol causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis[1].
Carvacrol is a monoterpenoid phenol isolated from Thymus mongolicus Ronn., with antioxidant, anti-inflammatory and anticancer properties. Carvacrol causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis[1].
同义名列表
52 个代谢物同义名
InChI=1\C10H14O\c1-7(2)9-5-4-8(3)10(11)6-9\h4-7,11H,1-3H; BENZENE,2-HYDROXY,4-ISOPROPYL,1-METHYL CARVACROL; 4-06-00-03331 (Beilstein Handbook Reference); 1-Methyl-2-hydroxy-4-isopropylbenzene; 1-Hydroxy-2-methyl-5-isopropylbenzene; Phenol, 2-methyl-5-(1-methylethyl)-; EPA Pesticide Chemical Code 022104; 2-Methyl-5-(1-methylethyl)phenol; Phenol, 5-isopropyl-2-methyl-; Phenol, 3-isopropyl-6-methyl-; 2-methyl-5-propan-2-yl-phenol; 2-methyl-5-propan-2-ylphenol; 5-Isopropyl-2-methyl-phenol; 5-isopropyl-2-methylphenol; 2-Methyl-5-isopropylphenol; 3-Isopropyl-6-methylphenol; 6-Methyl-3-isopropylphenol; o-Cresol, 5-isopropyl-; 5-Isopropyl-o-cresol; p-Cymene, 2-hydroxy-; Isopropyl-o-cresol; 2-Hydroxy-p-cymene; WLN: QR B1 EY1&1; EINECS 207-889-6; Cymene-2-ol, p-; Caswell No. 511; W224502_ALDRICH; 282197_ALDRICH; FEMA No. 2245; ZINC00967563; LMPR01020050; p-Cymen-2-ol; 2-p-Cymenol; AIDS-032320; BRN 1860514; 22051_FLUKA; CCRIS 7450; AIDS032320; Antioxine; Karvakrol; Carvacrol; Isothymol; AI3-03438; o-Thymol; NSC 6188; 499-75-2; HSDB 906; LS-2614; NSC6188; C09840; Carvacrol; Carvacrol
数据库引用编号
15 个数据库交叉引用编号
- ChEBI: CHEBI:3440
- KEGG: C09840
- PubChem: 10364
- ChEMBL: CHEMBL281202
- CAS: 499-75-2
- PubChem: 12027
- LipidMAPS: LMPR0102090017
- KNApSAcK: C00000156
- PDB-CCD: S5V
- 3DMET: B03314
- NIKKAJI: J6.180H
- medchemexpress: HY-N0711
- LOTUS: LTS0012882
- wikidata: Q225543
- KNApSAcK: 3440
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
277 个相关的物种来源信息
- 282714 - Achillea abrotanoides: 10.1016/0305-1978(92)90070-T
- 282717 - Achillea ageratum: 10.1002/(SICI)1099-1573(199605)10:3<248::AID-PTR807>3.0.CO;2-9
- 282720 - Achillea aspleniifolia:
- 282738 - Achillea fragrantissima: 10.1002/JPS.2600531215
- 282739 - Achillea grandifolia: 10.1055/S-2006-961401
- 13329 - Achillea millefolium:
- 282770 - Achillea virescens:
- 205360 - Ajania fastigiata: 10.1007/BF00568252
- 49984 - Ajuga chamaepitys: 10.1080/10412905.1999.9701111
- 925377 - Aloysia citrodora: 10.1080/10412905.1994.9698440
- 542672 - Aloysia triphylla: 10.1080/10412905.1994.9698440
- 299928 - Alpinia latilabris: 10.1080/10412905.1994.9698447
- 175694 - Andrographis paniculata (Burm f.) Nees: -
- 165353 - Angelica sinensis:
- 165353 - Angelica sinensis (Oliv.)Diels: -
- 489372 - Anisosciadium orientale: 10.23893/1307-2080.APS.05611
- 589713 - Anthemis aciphylla: 10.1248/CPB.54.222
- 35608 - Artemisia annua: 10.1007/S11418-007-0175-2
- 262982 - Artemisia apiacea: 10.1007/S11418-007-0175-2
- 259893 - Artemisia argyi: 10.1007/S11418-007-0175-2
- 259893 - Artemisia argyi Lévl.et Vant.: -
- 265783 - Artemisia capillaris: 10.1007/S11418-007-0175-2
- 496566 - Artemisia carvifolia: 10.1007/S11418-007-0175-2
- 1473222 - Artemisia cina: 10.1007/S11418-007-0175-2
- 72341 - Artemisia dracunculus: 10.1007/S11418-007-0175-2
- 401898 - Artemisia gmelinii: 10.1007/S11418-007-0175-2
- 72329 - Artemisia herba-alba: 10.1016/J.ARABJC.2012.04.042
- 205369 - Artemisia judaica: 10.1080/10412905.1990.9697881
- 86312 - Artemisia ludoviciana: 10.1076/PHBI.40.4.263.8465
- 669134 - Artemisia montana: 10.1007/S11418-007-0175-2
- 223870 - Artemisia princeps: 10.1007/S11418-007-0175-2
- 72351 - Artemisia scoparia: 10.1007/S11418-007-0175-2
- 401933 - Artemisia sericea: 10.1007/S11418-007-0175-2
- 55611 - Artemisia tridentata: 10.1021/JF60210A021
- 366663 - Asarum heterotropoides Fr.Schmidt var.mandshuricum(Maxim.)Kitag.: -
- 76098 - Asarum sieboldii Miq.: -
- 76098 - Asarum sieboldii Miq.var.seoulense Nakai: -
- 109086 - Athamanta macedonica: 10.1080/10412905.1995.9698532
- 72900 - Baccharis dracunculifolia: 10.1248/CPB.54.1465
- 199392 - Baeckea frutescens: 10.1002/(SICI)1099-1026(1998070)13:4<245::AID-FFJ736>3.0.CO;2-J
- 1685994 - Betula pubescens var. litwinowii: 10.1007/BF02236421
- 375214 - Blepharocalyx salicifolius: 10.1021/NP50035A036
- 260124 - Blepharocalyx tweediei: 10.1021/NP50035A036
- 199133 - Bupleurum fruticescens: 10.1055/S-2006-959755
- 48103 - Bupleurum fruticosum: 10.1021/NP50062A008
- 300208 - Canarium album: 10.1007/S10600-006-0204-5
- 300208 - Canarium album Raeusch.: -
- 3483 - Cannabis sativa: 10.1021/NP50008A001
- 996322 - Cantinoa mutabilis: 10.1021/NP50034A044
- 48032 - Carum carvi: 10.1021/JF051513Y
- 99037 - Chamaemelum nobile: 10.1055/S-2006-960081
- 1548557 - Chiliadenus lopadusanus: 10.1055/S-2007-969050
- 119260 - Cinnamomum aromaticum: 10.1007/S11418-006-0039-1
- 13429 - Cinnamomum camphora: 10.1007/S11418-006-0039-1
- 1155220 - Cinnamomum iners: 10.1007/S11418-006-0039-1
- 128608 - Cinnamomum verum:
- 79217 - Citrus iyo: 10.1271/BBB1961.47.1841
- 85571 - Citrus Reticulata: -
- 751789 - Clinopodium carolinianum: 10.1055/S-2006-959714
- 887129 - Clinopodium grandiflorum: 10.1055/S-2006-959714
- 2171722 - Coleus aegyptiacus: 10.1002/FFJ.2730080110
- 204180 - Coleus amboinicus: 10.1007/BF01961467
- 4047 - Coriandrum sativum: 10.1021/JF00029A021
- 2815083 - Croton mucronifolius: 10.5897/JMPR10.078
- 52462 - Cuminum cyminum: 10.1021/JF051513Y
- 329091 - Cupressus torulosa: 10.3891/ACTA.CHEM.SCAND.15-1313
- 329091 - Cupressus torulosa var. torulosa: 10.3891/ACTA.CHEM.SCAND.15-1313
- 751776 - Cyclotrichium niveum: 10.1080/10412905.1994.9698316
- 79841 - Cymbopogon schoenanthus: 10.1016/J.APJTM.2016.06.009
- 512623 - Cyperus rotundus: 10.1016/J.APJTM.2016.06.009
- 489373 - Echinophora orientalis: 10.23893/1307-2080.APS.05611
- 99501 - Echinophora tenuifolia:
- 109117 - Echinophora tournefortii: 10.23893/1307-2080.APS.05611
- 1711250 - Eucalyptus dealbata: 10.1080/10412905.1992.9698129
- 1514027 - Ferula jaeschkeana: 10.1016/0031-9422(89)80069-X
- 371376 - Ferula ovina: 10.1080/10412905.2005.9698829
- 1603725 - Flemingia Prostrata Roxb: -
- 38851 - Gentiana lutea:
- 148894 - Geum heterocarpum: 10.1080/10412905.1994.9698398
- 49827 - Glycyrrhiza glabra:
- 3635 - Gossypium hirsutum: 10.1021/JF60200A011
- 1770161 - Griffitharia pallescens:
- 165083 - Gundelia tournefortii: 10.1080/13880200500220268
- 261776 - Helichrysum arenarium: 10.1080/10412905.2000.9712202
- 112363 - Helichrysum odoratissimum: 10.1080/10412905.1993.9698178
- 714477 - Homalomena Occulta (Lour.) Schott: -
- 16752 - Houttuynia cordata:
- 228586 - Humulus Scandens (Lour.) Merr.: -
- 260601 - Hyssopus seravschanicus: 10.1007/BF00568256
- 124778 - Illicium verum: 10.1021/JF051513Y
- 662920 - Isodon melissoides: 10.1055/S-2007-970006
- 16719 - Juglans nigra: 10.1080/10412905.1992.9698128
- 48063 - Lagoecia cuminoides: 10.1080/10412905.2004.9698641
- 63011 - Laser trilobum: 10.1080/10412905.1992.9698019
- 85223 - Laurus nobilis:
- 39331 - Lavandula latifolia: 10.1016/0031-9422(83)85052-3
- 260634 - Lavandula multifida: 10.1016/J.PHYMED.2004.02.007
- 268881 - Lepechinia chamaedryoides: 10.1055/S-2006-961452
- 48042 - Levisticum officinale:
- 1986359 - Lippia graveolens:
- 1241429 - Lippia micromera: 10.1080/10412905.1998.9700875
- 542673 - Lippia origanoides:
- 320357 - Lippia sidoides: 10.1021/NP50044A019
- 105884 - Lonicera japonica: 10.1021/JF950275B
- 105884 - Lonicera japonica Thunb.: -
- 85864 - Magnolia Officinalis Rehd Et Wils\uff0e: -
- 2291702 - Marrubium parviflorum: 10.1080/10412905.1999.9701138
- 39338 - Melissa officinalis: 10.1007/BF01167568
- 38859 - Mentha longifolia: 10.1002/PTR.2650040606
- 294739 - Mentha pulegium: 10.1021/JF00056A055
- 29719 - Mentha spicata: 10.1002/PTR.2650040606
- 38860 - Mentha suaveolens: 10.1002/PTR.2650040606
- 306395 - Micromeria juliana: 10.1080/10412905.1991.9697971
- 1970105 - Micromeria myrtifolia: 10.1080/10412905.1992.9698015
- 1132402 - Micromeria nervosa: 10.1016/S0378-8741(97)00088-3
- 182379 - Monarda citriodora: 10.1080/10412905.1994.9698320
- 39344 - Monarda fistulosa:
- 182387 - Monarda punctata: 10.1016/J.PHYTOCHEM.2010.08.009
- 2006539 - Mosla cavaleriei: 10.1080/10412905.1995.9698478
- 516065 - Mosla chinensis:
- 51089 - Myristica fragrans: 10.1021/JF051513Y
- 119949 - Myrtus communis:
- 54731 - Nepeta racemosa: 10.1080/10412905.1993.9698205
- 555479 - Nigella sativa:
- 39350 - Ocimum basilicum: 10.1080/10412905.1995.9698501
- 204144 - Ocimum gratissimum:
- 204149 - Ocimum tenuiflorum: 10.1007/BF03045450
- 881598 - Ocotea corymbosa: 10.1016/0031-9422(94)00977-2
- 1268181 - Origanum acutidens: 10.1080/10412905.1997.9700721
- 1268184 - Origanum bilgeri: 10.1007/BF01167568
- 1268187 - Origanum cordifolium: 10.1016/0378-8741(91)90063-J
- 497761 - Origanum dictamnus: 10.1055/S-2006-962640
- 1268191 - Origanum hypericifolium:
- 268884 - Origanum majorana:
- 1268194 - Origanum minutiflorum:
- 1268195 - Origanum munzurense: 10.1007/BF01167568
- 452416 - Origanum onites:
- 1132404 - Origanum sipyleum: 10.1080/10412905.1992.9698035
- 1082757 - Origanum syriacum:
- 39352 - Origanum vulgare:
- 35924 - Paeonia lactiflora:
- 45171 - Paeonia suffruticosa: 10.1080/00021369.1983.10866058
- 392747 - Paullinia cupana: 10.1007/BF01267777
- 158596 - Pelargonium endlicherianum: 10.1055/S-2006-960872
- 253082 - Pelargonium quercifolium: 10.1080/10412905.1991.9697953
- 48386 - Perilla Frutescens: -
- 608512 - Perilla frutescens var. hirtella: 10.1248/BPB.23.359
- 3435 - Persea americana: 10.1021/JF00035A029
- 997723 - Phlomis lanata: 10.1002/FFJ.1305
- 222877 - Phyla nodiflora: 10.1021/NP50039A037
- 375272 - Pimenta dioica: 10.1080/10412905.1997.9700812
- 260139 - Pimenta racemosa: 10.1080/10412905.1991.9697952
- 271192 - Pimpinella anisum: 10.1016/S0031-9422(98)00022-3
- 58041 - Pinus cembra: 10.1016/S0021-9673(01)84593-3
- 71633 - Pinus halepensis: 10.1016/S0021-9673(01)84593-3
- 13217 - Piper betle: 10.1016/S0031-9422(97)00737-1
- 13216 - Piper nigrum: 10.1021/JF051513Y
- 55513 - Pistacia vera: 10.1080/10412905.1995.9698558
- 33090 - Plants: -
- 174549 - Polygala senega: 10.1002/FFJ.2730100408
- 46147 - Portulaca oleracea: 10.1016/J.TALANTA.2009.11.047
- 1925587 - Prangos uechtritzii: 10.1055/S-2000-8627
- 313948 - Rhanterium epapposum: 10.1002/FFJ.2730020106
- 203015 - Rhodiola rosea: 10.1016/S0031-9422(02)00004-3
- 1980289 - Rhododendron columbianum: 10.1002/JPS.3080230706
- 49605 - Rhododendron groenlandicum: 10.1002/JPS.3080230706
- 1933698 - Salvia absconditiflora: 10.1080/10412905.1995.9698479
- 1933710 - Salvia caespitosa: 10.1080/10412905.1995.9698508
- 268906 - Salvia fruticosa:
- 396869 - Salvia pomifera: 10.1080/10412905.2000.9712167
- 39367 - Salvia rosmarinus:
- 38869 - Salvia sclarea: 10.1076/PHBI.35.3.218.13295
- 41644 - Santolina chamaecyparissus: 10.1021/NP50048A037
- 1142017 - Santolina corsica: 10.1016/S0378-8741(97)01528-6
- 765941 - Santolina insularis: 10.1016/S0378-8741(97)01528-6
- 546409 - Satureja cuneifolia:
- 49987 - Satureja hortensis:
- 49988 - Satureja montana:
- 751861 - Satureja parnassica:
- 412922 - Satureja spicigera:
- 49989 - Satureja thymbra:
- 2816102 - Seriphium plumosum: 10.1076/PHBI.35.1.66.13267
- 403014 - Sideritis cretica: 10.3906/KIM-1206-45
- 155254 - Sideritis montana: 10.1076/1388-0209(200004)3821-1FT106
- 155260 - Sideritis romana: 10.1076/1388-0209(200004)3821-1FT106
- 155265 - Sideritis syriaca: 10.3906/KIM-1206-45
- 155267 - Sideritis tragoriganum: 10.1016/B978-0-444-88558-6.50020-9
- 53737 - Sphagneticola trilobata: 10.1002/FFJ.3227
- 194217 - Stachys cretica: 10.1007/BF01167568
- 142738 - Stellera chamaejasme: 10.1080/14786419.2010.532796
- 55670 - Stevia rebaudiana: 10.1002/FFJ.2730010103
- 1735431 - Stoebe plumosa: 10.1076/PHBI.35.1.66.13267
- 1237821 - Stoebe vulgaris: 10.1076/PHBI.35.1.66.13267
- 219868 - Syzygium aromaticum: 10.1021/JF051513Y
- 58860 - Tamarindus indica: 10.1080/10412905.1994.9698449
- 127999 - Tanacetum parthenium: 10.1002/(SICI)1099-1026(199611)11:6<367::AID-FFJ598>3.0.CO;2-R
- 13717 - Tetraclinis articulata: 10.3891/ACTA.CHEM.SCAND.16-1291
- 1209851 - Teucrium cyprium: 10.1016/0378-8741(91)90062-I
- 1209865 - Teucrium kotschyanum: 10.1016/0378-8741(91)90062-I
- 1423403 - Teucrium leucocladum: 10.1016/J.BSE.2003.12.009
- 1117157 - Teucrium polium: 10.1021/NP50039A032
- 3317 - Thuja occidentalis:
- 13727 - Thujopsis dolabrata:
- 543980 - Thymbra capitata:
- 751867 - Thymbra sintenisii: 10.1007/BF01167568
- 306406 - Thymbra spicata:
- 751869 - Thymus broussonetii:
- 2662188 - Thymus carmanicus: 10.1055/S-0029-1243136
- 1885666 - Thymus cilicicus: 10.1055/S-2007-969176
- 1885667 - Thymus eigii:
- 2019953 - Thymus fedtschenkoi: 10.1021/NP50047A039
- 2019954 - Thymus kotschyanus:
- 1194133 - Thymus longicaulis:
- 532140 - Thymus marschallianus: 10.1007/BF00579141
- 2019957 - Thymus migricus: 10.1002/FFJ.1036
- 347388 - Thymus praecox: 10.1007/BF01167568
- 497663 - Thymus pubescens: 10.1055/S-0029-1243136
- 751873 - Thymus pulegioides: 10.1016/0305-1978(94)90086-8
- 228974 - Thymus quinquecostatus:
- 1268205 - Thymus revolutus:
- 751874 - Thymus saturejoides:
- 1718167 - Thymus sibthorpii:
- 49992 - Thymus vulgaris:
- 1132412 - Thymus zygioides:
- 52570 - Trachyspermum ammi:
- 53022 - Trichocolea tomentella: 10.1016/0031-9422(81)85270-3
- 118778 - Tussilago farfara: 10.1248/YAKUSHI1947.112.8_571
- 945837 - Vaccinium ashei: 10.1111/J.1365-2621.1985.TB13419.X
- 69266 - Vaccinium corymbosum: 10.1111/J.1365-2621.1985.TB13419.X
- 13750 - Vaccinium macrocarpon: 10.3891/ACTA.CHEM.SCAND.21-2076
- 1493660 - Vaccinium virgatum: 10.1111/J.1365-2621.1985.TB13419.X
- 180772 - Vaccinium vitis-idaea: 10.3891/ACTA.CHEM.SCAND.21-0945
- 19953 - Valeriana officinalis: 10.1016/0305-1978(84)90011-5
- 552636 - Xanthium strumarium var. canadense: 10.1021/NP50041A038
- 1005655 - Xylopia aromatica: 10.1080/10412905.1993.9698250
- 1005659 - Xylopia sericea: 10.1021/NP50048A039
- 751877 - Zataria multiflora: 10.1002/1099-1026(200011/12)15:6<373::AID-FFJ923>3.0.CO;2-9
- 4577 - Zea mays: 10.1021/JF60218A022
- 4650 - Zingiber: 10.1021/JF051513Y
- 94328 - Zingiber Officinale Roscoe: -
- 219868 - 丁香: -
- 3252 - 伸筋草: -
- 83936 - 凌霄花: -
- 33090 - 千年健: -
- 1603725 - 千斤拔: -
- 85864 - 厚朴: -
- 33090 - 当归: -
- 33090 - 木香: -
- 33090 - 枇杷叶: -
- 33090 - 柴胡: -
- 13428 - 桂枝: -
- 33090 - 款冬花: -
- 312530 - 独活: -
- 33090 - 玉米须: -
- 33090 - 生姜: -
- 33090 - 白芷: -
- 33090 - 百合: -
- 33090 - 矮地茶: -
- 33090 - 穿心莲: -
- 33090 - 紫苏: -
- 33090 - 绞股蓝: -
- 33090 - 羌活: -
- 33090 - 艾叶: -
- 4047 - 芫荽: -
- 33090 - 苍耳子: -
- 13422 - 菊花: -
- 33090 - 葎草: -
- 33090 - 薄荷: -
- 33090 - 藁本: -
- 33090 - 豆蔻: -
- 33090 - 辛夷: -
- 33090 - 郁金: -
- 33090 - 金银花: -
- 33090 - 陈皮: -
- 33090 - 香薷: -
- 33090 - 鹅不食草: -
- 33090 - 麻黄: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Mitsue Ito, Natânia C Sperandio, Ygor H da Silva, Jankerle N Boeloni, Mariana D C Ignacchiti, Barbara R de Avelar, Vagner T de Queiroz, Adilson V Costa, Isabella V F Martins. Chemical composition and effect of essential oils of Thymus vulgaris and Origanum vulgare on adults and ovigerous masses of Pseudosuccinea columella.
Natural product research.
2024 Jun; 38(12):2007-2011. doi:
10.1080/14786419.2023.2233046
. [PMID: 37408510] - Stoja Milovanovic, Darka Markovic, Ivona Jankovic-Castvan, Ivana Lukic. Cornstarch aerogels with thymol, citronellol, carvacrol, and eugenol prepared by supercritical CO2- assisted techniques for potential biomedical applications.
Carbohydrate polymers.
2024 May; 331(?):121874. doi:
10.1016/j.carbpol.2024.121874
. [PMID: 38388060] - Jiayu Yin, Shuang Wu, Yongli Yang, Delu Wang, Yue Ma, Yongtian Zhao, Sujitraj Sheth, Honglin Huang, Baoan Song, Zhuo Chen. In Addition to Damaging the Plasma Membrane, Phenolic Monoterpenoid Carvacrol Can Bind to the Minor Groove of DNA of Phytopathogenic Fungi to Potentially Control Tea Leaf Spot Caused by Lasiodiplodia theobromae.
Phytopathology.
2024 Apr; 114(4):700-716. doi:
10.1094/phyto-07-23-0263-r
. [PMID: 37856707] - Olga O Anjos, Matheus N Gomes, Caio P Tavares, Dauana M Sousa, Caritas J S Mendonça, José Reck, Adeilton P Maciel, Livio M Costa-Junior. Polymeric films of corn starch enhance the lethal effects of thymol and carvacrol terpenes upon Rhipicephalus microplus ticks.
Veterinary parasitology.
2024 Apr; 327(?):110149. doi:
10.1016/j.vetpar.2024.110149
. [PMID: 38412588] - Qingfeng Dong, Yaqi Dai, Weiting Wang, Yanli Ma, Li Li. Fabrication of carvacrol loaded cellulose acetate phthalate/shellac composite film and its application to mackerel fillets preservation.
International journal of biological macromolecules.
2024 Mar; 262(Pt 1):129904. doi:
10.1016/j.ijbiomac.2024.129904
. [PMID: 38311137] - Aditi Dahiya, Vishal Sharad Chaudhari, Priya Kushram, Susmita Bose. 3D Printed SiO2-Tricalcium Phosphate Scaffolds Loaded with Carvacrol Nanoparticles for Bone Tissue Engineering Application.
Journal of medicinal chemistry.
2024 Feb; 67(4):2745-2757. doi:
10.1021/acs.jmedchem.3c01884
. [PMID: 38146876] - Mohamad Khalil, Francesca Piccapane, Mirco Vacca, Giuseppe Celano, Laura Mahdi, Valeria Perniola, Carmen Aurora Apa, Alessandro Annunziato, Ilaria Iacobellis, Giuseppe Procino, Maria Calasso, Maria De Angelis, Rosa Caroppo, Piero Portincasa. Nutritional and Physiological Properties of Thymbra spicata: In Vitro Study Using Fecal Fermentation and Intestinal Integrity Models.
Nutrients.
2024 Feb; 16(5):. doi:
10.3390/nu16050588
. [PMID: 38474717] - Pooja Choudhary, Gaurav Bhanjana, Sandeep Kumar, Neeraj Dilbaghi. Development and evaluation of eco-friendly carvacrol nanoemulsion as a sustainable biopesticide against bacterial leaf blight of cluster bean.
Pest management science.
2024 Feb; 80(2):452-462. doi:
10.1002/ps.7776
. [PMID: 37721471] - Wen-Yan Duan, Xi-Man Zhu, Shuai-Bing Zhang, Yang-Yong Lv, Huan-Chen Zhai, Shan Wei, Ping-An Ma, Yuan-Sen Hu. Antifungal effects of carvacrol, the main volatile compound in Origanum vulgare L. essential oil, against Aspergillus flavus in postharvest wheat.
International journal of food microbiology.
2024 Jan; 410(?):110514. doi:
10.1016/j.ijfoodmicro.2023.110514
. [PMID: 38070224] - Eliška Hakalová, Dorota A Tekielska, Jan Wohlmuth, Jana Čechová. Management of bacterial blight of carrots by phenolic compounds treatment.
PloS one.
2024; 19(4):e0299105. doi:
10.1371/journal.pone.0299105
. [PMID: 38557606] - Jian-Guo Li, Xiao-Feng Chen, Ting-Yin Lu, Jing Zhang, Shu-He Dai, Jian Sun, Ya-Hong Liu, Xiao-Ping Liao, Yu-Feng Zhou. Increased Activity of β-Lactam Antibiotics in Combination with Carvacrol against MRSA Bacteremia and Catheter-Associated Biofilm Infections.
ACS infectious diseases.
2023 Dec; 9(12):2482-2493. doi:
10.1021/acsinfecdis.3c00338
. [PMID: 38019707] - Isaac Konig, Nazish Iftikhar, Evelyn Henry, Cole English, Emma Ivantsova, Christopher L Souders, Silvana Marcussi, Christopher J Martyniuk. Toxicity assessment of carvacrol and its acetylated derivative in early staged zebrafish (Danio rerio): Safer alternatives to fipronil-based pesticides?.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2023 Dec; 274(?):109762. doi:
10.1016/j.cbpc.2023.109762
. [PMID: 37813296] - Hind Zejli, Aziza Fitat, Youssra Lefrioui, Farhan Siddique, Mohammed Bourhia, Fatima Zahra Bousseraf, Ahmad Mohammad Salamatullah, Hiba-Allah Nafidi, Amare Bitew Mekonnen, Abdelkader Gourch, Mustapha Taleb, Abdelfattah Abdellaoui. Phytochemical analysis and biological activities of essential oils extracted from Origanum grossii and Thymus pallidus: in vitro and in silico analysis.
Scientific reports.
2023 11; 13(1):20021. doi:
10.1038/s41598-023-47215-4
. [PMID: 37973884] - Xinyi Yang, Pujiang Deng, Qiuyue Liu, Yangguang Meng, Pengpeng Dong, Liangsheng Xu, Lili Huang. Exploring the efficacy of carvacrol as a biocontrol agent against pear Valsa canker.
Pesticide biochemistry and physiology.
2023 Nov; 196(?):105641. doi:
10.1016/j.pestbp.2023.105641
. [PMID: 37945237] - Caroline Deweer, Karin Sahmer, Jérôme Muchembled. Anti-oomycete activities from essential oils and their major compounds on Phytophthora infestans.
Environmental science and pollution research international.
2023 Oct; ?(?):. doi:
10.1007/s11356-023-29270-6
. [PMID: 37779122] - Juliana Oliveira-Fernandes, Paulo R Oliveira-Pinto, Nuno Mariz-Ponte, Rose M O F Sousa, Conceição Santos. Satureja montana and Mentha pulegium essential oils' antimicrobial properties against Pseudomonas syringae pv. actinidiae and elicitor potential through the modulation of kiwifruit hormonal defenses.
Microbiological research.
2023 Sep; 277(?):127490. doi:
10.1016/j.micres.2023.127490
. [PMID: 37722185] - Katrin Bogun, Elisa Peh, Lisa Siekmann, Madeleine Plötz, Sophie Kittler. Combining antimicrobial substances for Campylobacter post harvest mitigation on chicken breast fillet and chicken skin - any synergistic effects?.
Journal of applied microbiology.
2023 Sep; 134(9):. doi:
10.1093/jambio/lxad209
. [PMID: 37709568] - Mbese Zintle, Peteni Siwaphiwe, Fotsing Marthe Carine, Fonkui Thierry Youmbi, Ndinteh Derek Tantoh, Ray Suprakas Sinha, Aderibigbe Blessing Atim. Antibacterial study of carbopol-mastic gum/silver nanoparticle-based topical gels with carvacrol/neem bark extract in vitro.
Journal of wound care.
2023 Sep; 32(Sup9a):clxxxi-clxxxix. doi:
10.12968/jowc.2023.32.sup9a.clxxxi
. [PMID: 37703219] - Rubeena Saleem, Aisha Sana, Yusra Ghani, Faiza Mushtaq, Rubina Abid, Jan Alam, Marium Tariq, Shahnaz Dawar, Razia Sultana, Shaheen Faizi. Chemical characterization, nematicidal and antioxidant activities of Thymus linearis Benth.
Pakistan journal of pharmaceutical sciences.
2023 Sep; 36(5):1561-1571. doi:
. [PMID: 37869932]
- Monique Taveira Medeiros, Diefrey Ribeiro Campos, Eduardo Fellipe Melo Santos Soares, Jéssica D 'avilla de Assis, Gabriela Ferreira de Oliveira, Larissa de Oliveira Santos, Taynara Monsores E Silva, Mathias Pittizer da Silva, Yara Peluso Cid, Fabio Barbour Scott, Katherina Comendouros. Larvicidal activity in vitro of essential oils against Cochliomyia hominivorax.
Veterinary parasitology.
2023 Aug; 322(?):110020. doi:
10.1016/j.vetpar.2023.110020
. [PMID: 37683367] - Sherief M Abdel-Raheem, Marwa I Abd El-Hamid, Doaa Ibrahim, Rania M S El-Malt, Waleed Rizk El-Ghareeb, Hesham A Ismail, Saad Ibrahim Al-Sultan, Ahmed M A Meligy, Reham M ELTarabili. Future scope of plant-derived bioactive compounds in the management of methicillin-resistant Staphylococcus aureus: In vitro antimicrobial and antivirulence prospects to combat MRSA.
Microbial pathogenesis.
2023 Aug; 183(?):106301. doi:
10.1016/j.micpath.2023.106301
. [PMID: 37579824] - Zahra Azimzadeh, Abbas Hassani, Babak Abdollahi Mandoulakani, Ebrahim Sepehr, Mohammad Reza Morshedloo. Intraspecific divergence in essential oil content, composition and genes expression patterns of monoterpene synthesis in Origanum vulgare subsp. vulgare and subsp. gracile under salinity stress.
BMC plant biology.
2023 Aug; 23(1):380. doi:
10.1186/s12870-023-04387-5
. [PMID: 37550621] - Chenghua Yan, Wendong Kuang, Liang Jin, Rongliang Wang, Ling Niu, Chuanqi Xie, Jian Ding, Yongcui Liao, Liyuan Wang, Hongjiao Wan, Guangqiang Ma. Carvacrol protects mice against LPS-induced sepsis and attenuates inflammatory response in macrophages by modulating the ERK1/2 pathway.
Scientific reports.
2023 08; 13(1):12809. doi:
10.1038/s41598-023-39665-7
. [PMID: 37550359] - Sameera Firdous, Showkat H Bhat, Safeena Aziz, Muneeza Jehangir, Sobiya Syeed, Zainab Iqra, Mohammad Abrar Ahmad, Shahid Rasool, Aadil Khursheed, Aabid Hussain Shalla, Arsheed A Ganaie, Manzoor A Rather. Antibacterial potential of Thymus linearis essential oil collected from Wasturwan mountain: A combination of experimental and theoretical studies involving in silico molecular docking simulation of the major compounds against Novobiocin-resistant mutant of DNA Gyrase-B.
Microbial pathogenesis.
2023 Aug; ?(?):106280. doi:
10.1016/j.micpath.2023.106280
. [PMID: 37541555] - Amira M Badr, Naglaa F El-Orabi, Yasmen F Mahran, Amul M Badr, Nervana Mustafa Bayoumy, Hanan Hagar, Elshaymaa I Elmongy, Reem T Atawia. In vivo and In silico evidence of the protective properties of carvacrol against experimentally-induced gastric ulcer: Implication of antioxidant, anti-inflammatory, and antiapoptotic mechanisms.
Chemico-biological interactions.
2023 Jul; 382(?):110649. doi:
10.1016/j.cbi.2023.110649
. [PMID: 37499997] - Diange Wu, Miao Xia, An Yan, Haotian Jiang, Jiaqi Fan, Siyuan Zhou, Xu Wei, Shudong Liu, Baojiang Chen. Carvacrol attenuated lipopolysaccharide-induced intestinal injury by down-regulating TLRs gene expression and regulating the gut microbiota in rabbit.
Scientific reports.
2023 07; 13(1):11447. doi:
10.1038/s41598-023-38577-w
. [PMID: 37454126] - Shiqin Chen, Yingying Shan, Chunlin Liu, Chungui Du, Jiawei Zhu, Fei Yang, Yuran Shao, Qichao Bao, Yuting Wang, Ying Ran, Wenxiu Yin. Antimildew Effect of Three Phenolic Compounds and the Efficacy of Antimildew Sliced Bamboo Veneer.
Molecules (Basel, Switzerland).
2023 Jun; 28(13):. doi:
10.3390/molecules28134941
. [PMID: 37446603] - Divek V T Nair, Shijinaraj Manjankattil, Claire Peichel, Wayne Martin, Annie M Donoghue, Kumar Venkitanarayanan, Anup Kollanoor Johny. Effect of plant-derived antimicrobials, eugenol, carvacrol, and β-resorcylic acid against Salmonella on organic chicken wings and carcasses.
Poultry science.
2023 Jun; 102(10):102886. doi:
10.1016/j.psj.2023.102886
. [PMID: 37517363] - Mahmoud Hosseini, Zohreh Arab, Farimah Beheshti, Akbar Anaeigoudari, Farzaneh Shakeri, Arezoo Rajabian. Zataria multiflora and its constituent, carvacrol, counteract sepsis-induced aortic and cardiac toxicity in rat: Involvement of nitric oxide and oxidative stress.
Animal models and experimental medicine.
2023 Jun; 6(3):221-229. doi:
10.1002/ame2.12323
. [PMID: 37272426] - Meiyu Sun, Ningning Liu, Jiahui Miao, Yanan Zhang, Yuanpeng Hao, Jinzheng Zhang, Hui Li, Hongtong Bai, Lei Shi. Creation of New Oregano Genotypes with Different Terpene Chemotypes via Inter- and Intraspecific Hybridization.
International journal of molecular sciences.
2023 Apr; 24(8):. doi:
10.3390/ijms24087320
. [PMID: 37108486] - Siyam Subair, Natasha Singh, Megha Maru, Sangeetha Prakash, Mohamed Hasanar. An Antimicrobial Fabric Using Nano-Herbal Encapsulation of Essential Oils.
Journal of visualized experiments : JoVE.
2023 04; ?(194):. doi:
10.3791/65187
. [PMID: 37092818] - Su-Yeon Park, Rifat Nowshin Raka, Xiu-Li Hui, Yang Song, Jin-Long Sun, Jie Xiang, Juan Wang, Jian-Ming Jin, Xu-Kai Li, Jun-Song Xiao, Hua Wu. Six Spain Thymus essential oils composition analysis and their in vitro and in silico study against Streptococcus mutans.
BMC complementary medicine and therapies.
2023 Apr; 23(1):106. doi:
10.1186/s12906-023-03928-7
. [PMID: 37020229] - Bartłomiej Piasecki, Viktória L Balázs, Anna Kieltyka-Dadasiewicz, Péter Szabó, Béla Kocsis, Györgyi Horváth, Agnieszka Ludwiczuk. Microbiological Studies on the Influence of Essential Oils from Several Origanum Species on Respiratory Pathogens.
Molecules (Basel, Switzerland).
2023 Mar; 28(7):. doi:
10.3390/molecules28073044
. [PMID: 37049808] - Mustafa Ileriturk, Fatih Mehmet Kandemir. Carvacrol protects against λ-Cyhalothrin-induced hepatotoxicity and nephrotoxicity by modulating oxidative stress, inflammation, apoptosis, endoplasmic reticulum stress, and autophagy.
Environmental toxicology.
2023 Mar; ?(?):. doi:
10.1002/tox.23784
. [PMID: 36947485] - Heider Carreño, Elena E Stashenko, Patricia Escobar. Essential Oils Distilled from Colombian Aromatic Plants and Their Constituents as Penetration Enhancers for Transdermal Drug Delivery.
Molecules (Basel, Switzerland).
2023 Mar; 28(6):. doi:
10.3390/molecules28062872
. [PMID: 36985843] - Panagiota G V Liggri, Katerina E Tsitsanou, Evgenia C V Stamati, Francesca Saitta, Christina E Drakou, Demetres D Leonidas, Dimitrios Fessas, Spyros E Zographos. The structure of AgamOBP5 in complex with the natural insect repellents Carvacrol and Thymol: Crystallographic, fluorescence and thermodynamic binding studies.
International journal of biological macromolecules.
2023 Mar; 237(?):124009. doi:
10.1016/j.ijbiomac.2023.124009
. [PMID: 36921814] - Sepideh Asadi, Bahar Nayeri-Fasaei, Taghi Zahraei-Salehi, Ramak Yahya-Rayat, Nemat Shams, Aram Sharifi. Antibacterial and anti-biofilm properties of carvacrol alone and in combination with cefixime against Escherichia coli.
BMC microbiology.
2023 Mar; 23(1):55. doi:
10.1186/s12866-023-02797-x
. [PMID: 36864390] - Spogmay Anwar, Arif-Ullah Khan, Nadeem Irshad. Pharmacological evaluation of carvacrol anti-migraine potential.
Naunyn-Schmiedeberg's archives of pharmacology.
2023 Feb; ?(?):. doi:
10.1007/s00210-023-02412-w
. [PMID: 36723608] - A T Shatarat, S H Halaiqah, I A Altarawneh, Z S Smadi, D H Badran, Mohamed K Al-Essa, F I Mohammed. Functional and morphological study of the effects of carvacrol on smooth muscle of the thoracic aorta in the rat.
Nigerian journal of clinical practice.
2023 Feb; 26(2):187-193. doi:
10.4103/njcp.njcp_397_22
. [PMID: 36876607] - Faezeh Karami, Dara Dastan, Mohammad Fallah, Mohammad Matini. In vitro antitrichomonal activity of Satureja khuzestanica and main essential oil components carvacrol, thymol, and eugenol.
Journal of infection in developing countries.
2023 Jan; 17(1):80-85. doi:
10.3855/jidc.16360
. [PMID: 36795930] - Israel Ehizuelen Ebhohimen, Ngozi P Okolie, Moses Okpeku, Mfon Unweator, Victoria T Adeleke, Lawrence Edemhanria. Evaluation of the Antioxidant Properties of Carvacrol as a Prospective Replacement for Crude Essential Oils and Synthetic Antioxidants in Food Storage.
Molecules (Basel, Switzerland).
2023 Jan; 28(3):. doi:
10.3390/molecules28031315
. [PMID: 36770981] - Alexandros Nakas, Georgia Giannarelli, Ioannis Fotopoulos, Eirini Chainoglou, Aikaterini Peperidou, Konstantinos N Kontogiannopoulos, Artemis Tsiaprazi-Stamou, Vasilios Varsamis, Helen Gika, Dimitra Hadjipavlou-Litina, Andreana N Assimopoulou. Optimizing the Distillation of Greek Oregano-Do Process Parameters Affect Bioactive Aroma Constituents and In Vitro Antioxidant Activity?.
Molecules (Basel, Switzerland).
2023 Jan; 28(3):. doi:
10.3390/molecules28030971
. [PMID: 36770638] - Esmaeil Rezaei-Chiyaneh, Hassan Mahdavikia, Hadi Alipour, Aria Dolatabadian, Martin Leonardo Battaglia, Sagar Maitra, Matthew Tom Harrison. Biostimulants alleviate water deficit stress and enhance essential oil productivity: a case study with savory.
Scientific reports.
2023 Jan; 13(1):720. doi:
10.1038/s41598-022-27338-w
. [PMID: 36639680] - Fan Su, Gan Yang, Datong Hu, Chen Ruan, Jing Wang, Yingying Zhang, Qingjun Zhu. Chemical Composition, Antibacterial and Antioxidant Activities of Essential Oil from Centipeda minima.
Molecules (Basel, Switzerland).
2023 Jan; 28(2):. doi:
10.3390/molecules28020824
. [PMID: 36677882] - Somayeh Shams, Ahmad Ismaili, Farhad Nazarian Firouzabadi, Hasan Mumivand, Karim Sorkheh. Comparative transcriptome analysis to identify putative genes involved in carvacrol biosynthesis pathway in two species of Satureja, endemic medicinal herbs of Iran.
PloS one.
2023; 18(7):e0281351. doi:
10.1371/journal.pone.0281351
. [PMID: 37418504] - Isaac Filipe Moreira Konig, Aline Chaves Reis, Mariana Aparecida Braga, Dirceu De Sousa Melo, Erika Aparecida Oliveira, Elaine Maria Seles Dorneles, Sérgio Scherrer Thomasi, Rafael Neodini Remedio, Silvana Marcussi. Comparative toxicological evaluation of carvacrol, acetylcarvacrol anda fipronil-based pesticide in human blood cells.
Drug and chemical toxicology.
2022 Dec; ?(?):1-10. doi:
10.1080/01480545.2022.2159428
. [PMID: 36541066] - Tülay Ceren Ölmeztürk Karakurt, İzzet Emir, Zehra Bedir, Kezban Tuna Ozkaloglu Erdem, Halis Süleyman, Cengiz Sarıgül, Ali Sefa Mendil. Effects of carvacrol on ketamine-induced cardiac injury in rats: an experimental study.
Drug and chemical toxicology.
2022 Dec; ?(?):1-6. doi:
10.1080/01480545.2022.2155664
. [PMID: 36511184] - AnildesI P Sousa, GlayaneJ S Castro, Caio P Tavares, Tássia L do Vale, Livio M Costa-Junior, AlexandraM S Soares. In vitro assessment of the acaricidal activity of a carvacrol shampoo on tick larvae.
Experimental parasitology.
2022 Nov; 242(?):108364. doi:
10.1016/j.exppara.2022.108364
. [PMID: 36027929] - Maryam Goharrostami, Jalal Jalali Sendi, Reza Hosseini, Nosrat O Allah Mahmoodi. Effect of thyme essential oil and its two components on toxicity and some physiological parameters in mulberry pyralid Glyphodes pyloalis Walker.
Pesticide biochemistry and physiology.
2022 Nov; 188(?):105220. doi:
10.1016/j.pestbp.2022.105220
. [PMID: 36464385] - Yuanpeng Hao, Xiaoqi Guo, Rui Yang, Yihao Yan, Meiyu Sun, Hui Li, Hongtong Bai, Hongxia Cui, Jingyi Li, Lei Shi. Unraveling the Biosynthesis of Carvacrol in Different Tissues of Origanum vulgare.
International journal of molecular sciences.
2022 Oct; 23(21):. doi:
10.3390/ijms232113231
. [PMID: 36362019] - Guodong Lin, Feng Cheng, Aoken Aimila, Junping Zhang, Maitinuer Maiwulanjiang. Process Optimization for Supercritical Carbon Dioxide Extraction of Origanum vulgare L. Essential Oil Based on the Yield, Carvacrol, and Thymol Contents.
Journal of AOAC International.
2022 Oct; 105(6):1719-1729. doi:
10.1093/jaoacint/qsac062
. [PMID: 35608311] - Yujing Wang, Liaoxi Tan, Kejun Jiao, Chu Xue, Qinglian Tang, Shan Jiang, Younan Ren, Hao Chen, Tarek Mohamed Abd El-Aziz, Khalid N M Abdelazeem, Ye Yu, Fang Zhao, Michael X Zhu, Zhengyu Cao. Scutellarein attenuates atopic dermatitis by selectively inhibiting transient receptor potential vanilloid 3 channels.
British journal of pharmacology.
2022 10; 179(20):4792-4808. doi:
10.1111/bph.15913
. [PMID: 35771623] - Shawky M Aboelhadid, Abdel-Azeem S Abdel-Baki, Khaled M Hassan, Waleed M Arafa, Heba Abdel-Tawab, Saleh Al-Quraishy, Ahmed O Hassan, Usama K Moawad, Osama Ahmed, Asmaa A Kamel. Role of antioxidant activity of essential oils in their acaricidal activities against Rhipicephalus annulatus.
Experimental & applied acarology.
2022 Oct; 88(2):209-224. doi:
10.1007/s10493-022-00742-7
. [PMID: 36348156] - Evan C Palmer-Young, Lindsey M Markowitz, Kyle Grubbs, Yi Zhang, Miguel Corona, Ryan Schwarz, Yanping Chen, Jay D Evans. Antiparasitic effects of three floral volatiles on trypanosomatid infection in honey bees.
Journal of invertebrate pathology.
2022 10; 194(?):107830. doi:
10.1016/j.jip.2022.107830
. [PMID: 36174749] - Zixu Huang, Sina Nazifi, Alireza Hakimian, Rojan Firuznia, Hadi Ghasemi. 'Built to Last': Plant-based Eco-friendly Durable Antibacterial Coatings.
ACS applied materials & interfaces.
2022 Sep; 14(38):43681-43689. doi:
10.1021/acsami.2c10285
. [PMID: 36099592] - Mahdieh Modareskia, Mohammad Fattahi, Mohammad Hossein Mirjalili. Thymol screening, phenolic contents, antioxidant and antibacterial activities of Iranian populations of Trachyspermum ammi (L.) Sprague (Apiaceae).
Scientific reports.
2022 Sep; 12(1):15645. doi:
10.1038/s41598-022-19594-7
. [PMID: 36123425] - Mohamad Khalil, Nadia Serale, Farah Diab, Francesca Baldini, Piero Portincasa, Giulio Lupidi, Laura Vergani. Beneficial Effects of Carvacrol on In Vitro Models of Metabolically-Associated Liver Steatosis and Endothelial Dysfunction: A Role for Fatty Acids in Interfering with Carvacrol Binding to Serum Albumin.
Current medicinal chemistry.
2022 08; 29(30):5113-5129. doi:
10.2174/0929867329666220401103643
. [PMID: 35366761] - Hatice Daldal, Mustafa Nazıroğlu. Carvacrol protects the ARPE19 retinal pigment epithelial cells against high glucose-induced oxidative stress, apoptosis, and inflammation by suppressing the TRPM2 channel signaling pathways.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie.
2022 Aug; 260(8):2567-2583. doi:
10.1007/s00417-022-05731-5
. [PMID: 35704089] - Niluni M Wijesundara, Song F Lee, H P Vasantha Rupasinghe. Carvacrol inhibits Streptococcus pyogenes biofilms by suppressing the expression of genes associated with quorum-sensing and reducing cell surface hydrophobicity.
Microbial pathogenesis.
2022 Aug; 169(?):105684. doi:
10.1016/j.micpath.2022.105684
. [PMID: 35863588] - Saheem Ahmad, Rabia Nabi, Sahir Sultan Alvi, Mahvish Khan, Saif Khan, Mohd Yasir Khan, Imran Hussain, S D Shahanawaz, M Salman Khan. Carvacrol protects against carbonyl osmolyte-induced structural modifications and aggregation to serum albumin: Insights from physicochemical and molecular interaction studies.
International journal of biological macromolecules.
2022 Jul; 213(?):663-674. doi:
10.1016/j.ijbiomac.2022.05.198
. [PMID: 35660040] - Natalia Vilmosh, Delyan Delev, Ilia Kostadinov, Hristina Zlatanova, Maria Kotetarova, Ilin Kandilarov, Ivanka Kostadinova. Anxiolytic Effect of Satureja montana Dry Extract and its Active Compounds Rosmarinic Acid and Carvacrol in Acute Stress Experimental Model.
Journal of integrative neuroscience.
2022 Jul; 21(5):124. doi:
10.31083/j.jin2105124
. [PMID: 36137956] - Cebrail Gursul, Adalet Ozcicek, Mustafa Ozkaraca, Ali Sefa Mendil, Taha Abdulkadir Coban, Aynur Arslan, Fatih Ozcicek, Halis Suleyman. Amelioration of oxidative damage parameters by carvacrol on methanol-induced liver injury in rats.
Experimental animals.
2022 May; 71(2):224-230. doi:
10.1538/expanim.21-0143
. [PMID: 34911876] - Mojtaba Khaksarian, Mahmoud Bahmani, Morovat Taherikalani, Behnam Ashrafi, Mahmoud Rafieian-Kopaei, Naser Abbasi. Biosynthesis of titanium dioxide nanoparticles using Hypericum perforatum and Origanum vulgare extracts and their main components, hypericin and carvacrol as promising antibacterial agents.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
2022 04; 42(2):167-175. doi:
10.19852/j.cnki.jtcm.2022.02.002
. [PMID: 35473336] - Mustafa Nazıroğlu. A novel antagonist of TRPM2 and TRPV4 channels: Carvacrol.
Metabolic brain disease.
2022 03; 37(3):711-728. doi:
10.1007/s11011-021-00887-1
. [PMID: 34989943] - Mishka Ismail, Vartika Srivastava, Musa Marimani, Aijaz Ahmad. Carvacrol modulates the expression and activity of antioxidant enzymes in Candida auris.
Research in microbiology.
2022 Mar; 173(3):103916. doi:
10.1016/j.resmic.2021.103916
. [PMID: 34863882] - Alireza Najafizadeh, Ayat Kaeidi, Mohammadreza Rahmani, Elham Hakimizadeh, Jalal Hassanshahi. The protective effect of carvacrol on acetaminophen-induced renal damage in male rats.
Molecular biology reports.
2022 Mar; 49(3):1763-1771. doi:
10.1007/s11033-021-06985-8
. [PMID: 35020122] - Canyang Niu, Xiaoying Sun, Fang Hu, Xiaowen Tang, KeWei Wang. Molecular determinants for the chemical activation of the warmth-sensitive TRPV3 channel by the natural monoterpenoid carvacrol.
The Journal of biological chemistry.
2022 03; 298(3):101706. doi:
10.1016/j.jbc.2022.101706
. [PMID: 35150742] - Carlos José Dias, Herikson Araújo Costa, Carlos Alberto Alves Dias-Filho, Andressa Coelho Ferreira, Bruno Rodrigues, Maria Claudia Irigoyen, Antônio Carlos Romão Borges, Vicenilma de Andadre Martins, Flávia Castello Branco Vidal, Rachel Melo Ribeiro, Natalino Salgado Filho, Cristiano T Mostarda. Carvacrol reduces blood pressure, arterial responsiveness and increases expression of MAS receptors in spontaneously hypertensive rats.
European journal of pharmacology.
2022 Feb; 917(?):174717. doi:
10.1016/j.ejphar.2021.174717
. [PMID: 34953800] - Marian G Sawerus, Olfat Shehata, Walaa M S Ahmed, Salama Shany, Kareem E Hassan, Emad A Mahdi, Amira H Mohamed. The modulatory effect of carvacrol on viral shedding titer and acute phase response in broiler chickens experimentally infected with infectious bronchitis virus.
Microbial pathogenesis.
2022 Feb; 163(?):105410. doi:
10.1016/j.micpath.2022.105410
. [PMID: 35041974] - Cristina Fuentes, Ana Fuentes, Hugh J Byrne, José Manuel Barat, María José Ruiz. In vitro toxicological evaluation of mesoporous silica microparticles functionalised with carvacrol and thymol.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2022 Feb; 160(?):112778. doi:
10.1016/j.fct.2021.112778
. [PMID: 34958804] - Kerim Yesildag, Cihan Gur, Mustafa Ileriturk, Fatih Mehmet Kandemir. Evaluation of oxidative stress, inflammation, apoptosis, oxidative DNA damage and metalloproteinases in the lungs of rats treated with cadmium and carvacrol.
Molecular biology reports.
2022 Feb; 49(2):1201-1211. doi:
10.1007/s11033-021-06948-z
. [PMID: 34792728] - Kristina Ložienė, Vaida Vaičiulytė. Geraniol and Carvacrol in Essential Oil Bearing Thymus pulegioides: Distribution in Natural Habitats and Phytotoxic Effect.
Molecules (Basel, Switzerland).
2022 Feb; 27(3):. doi:
10.3390/molecules27030986
. [PMID: 35164249] - Niluni M Wijesundara, Song F Lee, Ross Davidson, Zhenyu Cheng, H P Vasantha Rupasinghe. Carvacrol Suppresses Inflammatory Biomarkers Production by Lipoteichoic Acid- and Peptidoglycan-Stimulated Human Tonsil Epithelial Cells.
Nutrients.
2022 Jan; 14(3):. doi:
10.3390/nu14030503
. [PMID: 35276864] - Ariadna Thalia Bernal-Mercado, Josué Juarez, Miguel Angel Valdez, Jesus Fernando Ayala-Zavala, Carmen Lizette Del-Toro-Sánchez, David Encinas-Basurto. Hydrophobic Chitosan Nanoparticles Loaded with Carvacrol against Pseudomonas aeruginosa Biofilms.
Molecules (Basel, Switzerland).
2022 Jan; 27(3):. doi:
10.3390/molecules27030699
. [PMID: 35163966] - Songou Zhang, Lei He, Jinxiang Shang, Long Chen, Yifan Xu, Xiaozhen Chen, Xinyu Li, Qingchuan Jiao, Songtao Jin, Xujun Hu, Wenqing Liang. Carvacrol Suppresses Human Osteosarcoma Cells via the Wnt/β-Catenin Signaling Pathway.
Anti-cancer agents in medicinal chemistry.
2022; 22(9):1714-1722. doi:
10.2174/1871520621666210901111932
. [PMID: 34488595] - Xieling Yin, Hongjian Chen, Shi Chen, Suqing Zhang. Screening and Validation of a Carvacrol-Targeting Viability-Regulating Protein, SLC6A3, in Liver Hepatocellular Carcinoma.
Disease markers.
2022; 2022(?):3736104. doi:
10.1155/2022/3736104
. [PMID: 35401884] - Haoduo Yang, Ying Dong, Dongying Wang, Xuede Wang. Separated from the Essential Oil of Coriandrum sativum L. Leaves, Carvacrol and Limonene Showed Antioxidant Effects in Sunflower Oil under Frying Conditions.
Journal of oleo science.
2022; 71(8):1145-1158. doi:
10.5650/jos.ess22117
. [PMID: 35922929] - Muhammad Riaz, Lina Tariq Al Kury, Noreen Atzaz, Abdullah Alattar, Reem Alshaman, Fawad Ali Shah, Shupeng Li. Carvacrol Alleviates Hyperuricemia-Induced Oxidative Stress and Inflammation by Modulating the NLRP3/NF-κB Pathwayt.
Drug design, development and therapy.
2022; 16(?):1159-1170. doi:
10.2147/dddt.s343978
. [PMID: 35496367] - Daniele Fraternale, Hanh Dufat, Maria Cristina Albertini, Chouaha Bouzidi, Rossella D'Adderio, Sofia Coppari, Barbara Di Giacomo, Davide Melandri, Seeram Ramakrishna, Mariastella Colomba. Chemical composition, antioxidant and anti-inflammatory properties of Monarda didyma L. essential oil.
PeerJ.
2022; 10(?):e14433. doi:
10.7717/peerj.14433
. [PMID: 36438580] - Sandra T Krause, Pan Liao, Christoph Crocoll, Benoît Boachon, Christiane Förster, Franziska Leidecker, Natalie Wiese, Dongyan Zhao, Joshua C Wood, C Robin Buell, Jonathan Gershenzon, Natalia Dudareva, Jörg Degenhardt. The biosynthesis of thymol, carvacrol, and thymohydroquinone in Lamiaceae proceeds via cytochrome P450s and a short-chain dehydrogenase.
Proceedings of the National Academy of Sciences of the United States of America.
2021 12; 118(52):. doi:
10.1073/pnas.2110092118
. [PMID: 34930840] - Meilin Li, Shunlong Liu, Zhijuan Yin, Charlotte Bernigaud, Jacques Guillot, Fang Fang. Activity of terpenes derived from essential oils against Sarcoptes scabiei eggs.
Parasites & vectors.
2021 Dec; 14(1):600. doi:
10.1186/s13071-021-05094-6
. [PMID: 34886874] - Fernanda Oliveira de Carvalho, Jessica Paloma Rosa Silva, Érika Ramos Silva, Ricardo Luiz Cavalcanti de Albuquerque Júnior, Paula Santos Nunes, Adriano Antunes de Souza Araújo. Would carvacrol be a supporting treatment option effective in minimizing the deleterious effects of COVID-19?.
Naunyn-Schmiedeberg's archives of pharmacology.
2021 12; 394(12):2471-2474. doi:
10.1007/s00210-021-02170-7
. [PMID: 34669001] - Yeyen Laorenza, Nathdanai Harnkarnsujarit. Carvacrol, citral and α-terpineol essential oil incorporated biodegradable films for functional active packaging of Pacific white shrimp.
Food chemistry.
2021 Nov; 363(?):130252. doi:
10.1016/j.foodchem.2021.130252
. [PMID: 34118755] - Georgiana Ioana Potra Cicalău, Petru Aurel Babes, Horia Calniceanu, Adelina Popa, Gabriela Ciavoi, Gilda Mihaela Iova, Mariana Ganea, Ioana Scrobotă. Anti-Inflammatory and Antioxidant Properties of Carvacrol and Magnolol, in Periodontal Disease and Diabetes Mellitus.
Molecules (Basel, Switzerland).
2021 Nov; 26(22):. doi:
10.3390/molecules26226899
. [PMID: 34833990] - Wei Zhao, Li Chen, Heng Zhou, Chunyan Deng, Qizhen Han, Yonghua Chen, Qing Wu, Shanshan Li. Protective effect of carvacrol on liver injury in type 2 diabetic db/db mice.
Molecular medicine reports.
2021 11; 24(5):. doi:
10.3892/mmr.2021.12381
. [PMID: 34435648] - Farzad Kianersi, Alireza Pour-Aboughadareh, Mohammad Majdi, Peter Poczai. Effect of Methyl Jasmonate on Thymol, Carvacrol, Phytochemical Accumulation, and Expression of Key Genes Involved in Thymol/Carvacrol Biosynthetic Pathway in Some Iranian Thyme Species.
International journal of molecular sciences.
2021 Oct; 22(20):. doi:
10.3390/ijms222011124
. [PMID: 34681782] - Reza Mohebbati, Mohammad Jalili-Nik, Hossein Saghi, Hamed Sadatfaraji, Mohammad Soukhtanloo. Zataria multiflora and its main ingredient, carvacrol, affect on the renal function, histopathological, biochemical and antioxidant parameters in adriamycin-induced nephrotic rats.
Archives of physiology and biochemistry.
2021 Oct; 127(5):453-461. doi:
10.1080/13813455.2019.1650069
. [PMID: 31397187] - Shangbo Jiang, Jingxin Zhang, Qiyun Yang, Dayuan Sun, Xiaoming Pu, Huifang Shen, Qiqin Li, Zhongwen Wang, Birun Lin. Antimicrobial Activity of Natural Plant Compound Carvacrol Against Soft Rot Disease Agent Dickeya zeae.
Current microbiology.
2021 Sep; 78(9):3453-3463. doi:
10.1007/s00284-021-02609-3
. [PMID: 34263355] - S Das, R Chourashi, P Mukherjee, S Kundu, H Koley, M Dutta, A K Mukhopadhyay, K Okamoto, N S Chatterjee. Inhibition of growth and virulence of Vibrio cholerae by carvacrol, an essential oil component of Origanum spp.
Journal of applied microbiology.
2021 Sep; 131(3):1147-1161. doi:
10.1111/jam.15022
. [PMID: 33544959] - Taskeen Niaz, Muhammad Imran, Alan Mackie. Improving carvacrol bioaccessibility using core-shell carrier-systems under simulated gastrointestinal digestion.
Food chemistry.
2021 Aug; 353(?):129505. doi:
10.1016/j.foodchem.2021.129505
. [PMID: 33735775] - Saurav Ranjitkar, Delong Zhang, Fei Sun, Saleh Salman, Wu He, Kumar Venkitanarayanan, Edan R Tulman, Xiuchun Tian. Cytotoxic effects on cancerous and non-cancerous cells of trans-cinnamaldehyde, carvacrol, and eugenol.
Scientific reports.
2021 08; 11(1):16281. doi:
10.1038/s41598-021-95394-9
. [PMID: 34381064] - Fatih Mehmet Kandemir, Cuneyt Caglayan, Ekrem Darendelioğlu, Sefa Küçükler, Ebubekir İzol, Özge Kandemir. Modulatory effects of carvacrol against cadmium-induced hepatotoxicity and nephrotoxicity by molecular targeting regulation.
Life sciences.
2021 Jul; 277(?):119610. doi:
10.1016/j.lfs.2021.119610
. [PMID: 33989663] - Gen-Qiang Chen, Di Sun, Jin-Ming Yang, Song Zhang, Yue-E Tian, Zhi-Ping Che, Sheng-Ming Liu, Jia Jiang, Xiao-Min Lin. Synthesis of sulfonate derivatives of carvacrol and thymol as anti-oomycetes agents.
Journal of Asian natural products research.
2021 Jul; 23(7):692-702. doi:
10.1080/10286020.2020.1758675
. [PMID: 32406756] - Héloïse Côté, André Pichette, Alexis St-Gelais, Jean Legault. The Biological Activity of Monarda didyma L. Essential Oil and Its Effect as a Diet Supplement in Mice and Broiler Chicken.
Molecules (Basel, Switzerland).
2021 Jun; 26(11):. doi:
10.3390/molecules26113368
. [PMID: 34199656] - Saeideh Saadat, Mohammad Reza Aslani, Vahideh Ghorani, Rana Keyhanmanesh, Mohammad Hossein Boskabady. The effects of Nigella sativa on respiratory, allergic and immunologic disorders, evidence from experimental and clinical studies, a comprehensive and updated review.
Phytotherapy research : PTR.
2021 Jun; 35(6):2968-2996. doi:
10.1002/ptr.7003
. [PMID: 33455047] - Vahideh Ghorani, Azam Alavinezhad, Omid Rajabi, Mohammad Hossein Boskabady. Carvacrol improves pulmonary function tests, oxidant/antioxidant parameters and cytokine levels in asthmatic patients: A randomized, double-blind, clinical trial.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2021 May; 85(?):153539. doi:
10.1016/j.phymed.2021.153539
. [PMID: 33773189] - Yujing Wang, Hang Li, Chu Xue, Hao Chen, Yanning Xue, Fang Zhao, Michael X Zhu, Zhengyu Cao. TRPV3 enhances skin keratinocyte proliferation through EGFR-dependent signaling pathways.
Cell biology and toxicology.
2021 04; 37(2):313-330. doi:
10.1007/s10565-020-09536-2
. [PMID: 32535744] - Herikson Araujo Costa, Carlos José Moraes Dias, Vicenilma de Andrade Martins, Sandra Alves de Araujo, Daiane Pereira da Silva, Vinícius S Mendes, Mário Norberto Sevilio de Oliveira, Cristiano Teixeira Mostarda, Antônio Carlos Romão Borges, Rachel Melo Ribeiro, Natalino Salgado Filho. Effect of treatment with carvacrol and aerobic training on cardiovascular function in spontaneously hypertensive rats.
Experimental physiology.
2021 04; 106(4):891-901. doi:
10.1113/ep089235
. [PMID: 33595154] - T N S Oliveira, C M S Silva-Filho, E A Malveira, T K B Aguiar, H S Santos, C C Albuquerque, M B Morais, E H Teixeira, M A Vasconcelos. Antifungal and antibiofilm activities of the essential oil of leaves from Lippia gracilis Schauer against phytopathogenic fungi.
Journal of applied microbiology.
2021 Apr; 130(4):1117-1129. doi:
10.1111/jam.14857
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