Calpain Inhibitor I (BioDeep_00000008593)
代谢物信息卡片
Acetylleucyl-leucyl-norleucinal
化学式: C20H37N3O4 (383.2784)
中文名称: 钙蛋白酶抑制剂I
谱图信息:
最多检出来源 Mentha canadensis(plant) 6.67%
分子结构信息
SMILES: CCCCC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C
InChI: InChI=1S/C20H37N3O4/c1-7-8-9-16(12-24)22-19(26)18(11-14(4)5)23-20(27)17(10-13(2)3)21-15(6)25/h12-14,16-18H,7-11H2,1-6H3,(H,21,25)(H,22,26)(H,23,27)/t16-,17-,18-/m0/s1
描述信息
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D015853 - Cysteine Proteinase Inhibitors
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D007976 - Leupeptins
同义名列表
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:2423
- KEGG: C11306
- PubChem: 443118
- Metlin: METLIN68977
- DrugBank: DB07558
- ChEMBL: CHEMBL304784
- CAS: 110044-82-1
- PMhub: MS000022224
- PubChem: 13481
- PDB-CCD: CIB
- NIKKAJI: J675.054K
- RefMet: Acetylleucyl-leucyl-norleucinal
- KNApSAcK: 2423
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Emily G Hicks, Sylvie E Kandel, Jed N Lampe. Identification of Aloe-derived natural products as prospective lead scaffolds for SARS-CoV-2 main protease (Mpro) inhibitors.
Bioorganic & medicinal chemistry letters.
2022 06; 66(?):128732. doi:
10.1016/j.bmcl.2022.128732. [PMID: 35427739] - Jixin Liu, Qiuning Wang, Yujie Wei, Shining Zhang, Erqing Chai, Futian Tang. Calpain inhibitor prevents atherosclerosis in apolipoprotein E knockout mice by regulating mRNA expression of genes related to cholesterol uptake and efflux.
Microvascular research.
2022 03; 140(?):104276. doi:
10.1016/j.mvr.2021.104276. [PMID: 34742813] - Jennifer C Milligan, Theresa U Zeisner, George Papageorgiou, Dhira Joshi, Christelle Soudy, Rachel Ulferts, Mary Wu, Chew Theng Lim, Kang Wei Tan, Florian Weissmann, Berta Canal, Ryo Fujisawa, Tom Deegan, Hema Nagaraj, Ganka Bineva-Todd, Clovis Basier, Joseph F Curran, Michael Howell, Rupert Beale, Karim Labib, Nicola O'Reilly, John F X Diffley. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease.
The Biochemical journal.
2021 07; 478(13):2499-2515. doi:
10.1042/bcj20210197. [PMID: 34198327] - Nicholas E Calcaterra, Daniel J Hoeppner, Huijun Wei, Andrew E Jaffe, Brady J Maher, James C Barrow. Schizophrenia-Associated hERG channel Kv11.1-3.1 Exhibits a Unique Trafficking Deficit that is Rescued Through Proteasome Inhibition for High Throughput Screening.
Scientific reports.
2016 Feb; 6(?):19976. doi:
10.1038/srep19976. [PMID: 26879421] - Kazim Kartkaya, Güngör Kanbak, Ayşegül Oğlakçı, Dilek Burukoğlu, Mehmet Caner Ozer. Protective effect of calpain inhibitor N-acetyl-L-leucyl-L-leucyl-L-norleucinal on acute alcohol consumption related cardiomyopathy.
Molecular biology reports.
2014 Oct; 41(10):6743-53. doi:
10.1007/s11033-014-3560-4. [PMID: 24996291] - Riyoko Tamai, Yusuke Kiyoura. Candida albicans and Candida parapsilosis rapidly up-regulate galectin-3 secretion by human gingival epithelial cells.
Mycopathologia.
2014 Feb; 177(1-2):75-9. doi:
10.1007/s11046-013-9725-1. [PMID: 24436012] - Cynthia Chatterjee, Daniel L Sparks. Hepatic lipase release is inhibited by a purinergic induction of autophagy.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.
2014; 33(4):883-94. doi:
10.1159/000358661. [PMID: 24713587] - Chithra N Keembiyehetty, Anna Krzeslak, Dona C Love, John A Hanover. A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome.
Journal of cell science.
2011 Aug; 124(Pt 16):2851-60. doi:
10.1242/jcs.083287. [PMID: 21807949] - Yadira Bastián, Ana L Roa-Espitia, Adela Mújica, Enrique O Hernández-González. Calpain modulates capacitation and acrosome reaction through cleavage of the spectrin cytoskeleton.
Reproduction (Cambridge, England).
2010 Nov; 140(5):673-84. doi:
10.1530/rep-09-0545. [PMID: 20716611] - Verónica Pérez-De La Cruz, Diana Elinos-Calderón, Paul Carrillo-Mora, Daniela Silva-Adaya, Mina Konigsberg, Julio Morán, Syed F Ali, María Elena Chánez-Cárdenas, Gonzalo Pérez-De La Cruz, Abel Santamaría. Time-course correlation of early toxic events in three models of striatal damage: modulation by proteases inhibition.
Neurochemistry international.
2010 May; 56(6-7):834-42. doi:
10.1016/j.neuint.2010.03.008. [PMID: 20332007] - Mariko Nobukuni, Hideki Mochizuki, Satoshi Okada, Nobuhisa Kameyama, Anna Tanaka, Hikaru Yamamoto, Taku Amano, Takahiro Seki, Norio Sakai. The C-terminal region of serotonin transporter is important for its trafficking and glycosylation.
Journal of pharmacological sciences.
2009 Dec; 111(4):392-404. doi:
10.1254/jphs.09195fp. [PMID: 19946177] - Wei Qiu, Qiaozhu Su, Angela C Rutledge, Jing Zhang, Khosrow Adeli. Glucosamine-induced endoplasmic reticulum stress attenuates apolipoprotein B100 synthesis via PERK signaling.
Journal of lipid research.
2009 Sep; 50(9):1814-23. doi:
10.1194/jlr.m800343-jlr200. [PMID: 19383982] - Ioannis M Stylianou, Karen L Svenson, Sara K VanOrman, Yanina Langle, John S Millar, Beverly Paigen, Daniel J Rader. Novel ENU-induced point mutation in scavenger receptor class B, member 1, results in liver specific loss of SCARB1 protein.
PloS one.
2009 Aug; 4(8):e6521. doi:
10.1371/journal.pone.0006521. [PMID: 19654867] - Julie Tsai, Rianna Zhang, Wei Qiu, Qiaozhu Su, Mark Naples, Khosrow Adeli. Inflammatory NF-kappaB activation promotes hepatic apolipoprotein B100 secretion: evidence for a link between hepatic inflammation and lipoprotein production.
American journal of physiology. Gastrointestinal and liver physiology.
2009 Jun; 296(6):G1287-98. doi:
10.1152/ajpgi.90540.2008. [PMID: 19342510] - Zhi-Yuan Wu, Kun Chen, Bernard Haendler, Thomas V McDonald, Jin-Song Bian. Stimulation of N-terminal truncated isoform of androgen receptor stabilizes human ether-á-go-go-related gene-encoded potassium channel protein via activation of extracellular signal regulated kinase 1/2.
Endocrinology.
2008 Oct; 149(10):5061-9. doi:
10.1210/en.2007-1802. [PMID: 18599551] - Charles S Brown, William L Dean. Regulation of plasma membrane Ca2+-ATPase in human platelets by calpain.
Platelets.
2007 May; 18(3):207-11. doi:
10.1080/09537100600954037. [PMID: 17497432] - Eva-Maria Krämer-Albers, Katja Gehrig-Burger, Christoph Thiele, Jacqueline Trotter, Klaus-Armin Nave. Perturbed interactions of mutant proteolipid protein/DM20 with cholesterol and lipid rafts in oligodendroglia: implications for dysmyelination in spastic paraplegia.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2006 Nov; 26(45):11743-52. doi:
10.1523/jneurosci.3581-06.2006. [PMID: 17093095] - Hui-nan Yin, Jia-ke Chai, Yong-ming Yao, Chuan-an Shen, Yan-qiu Wu, Zhong-feng Ma, Qiang Liu, Zhi-yong Sheng. [Effect of ubiquitin-proteasome pathway on inflammatory reaction in intestine and its barrier function in rats with postburn sepsis].
Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue.
2006 Nov; 18(11):649-52. doi:
NULL. [PMID: 17092411] - T Ohse, R Inagi, T Tanaka, T Ota, T Miyata, I Kojima, J R Ingelfinger, S Ogawa, T Fujita, M Nangaku. Albumin induces endoplasmic reticulum stress and apoptosis in renal proximal tubular cells.
Kidney international.
2006 Oct; 70(8):1447-55. doi:
10.1038/sj.ki.5001704. [PMID: 16955111] - Yuki Ohsaki, Jinglei Cheng, Akikazu Fujita, Toshinobu Tokumoto, Toyoshi Fujimoto. Cytoplasmic lipid droplets are sites of convergence of proteasomal and autophagic degradation of apolipoprotein B.
Molecular biology of the cell.
2006 Jun; 17(6):2674-83. doi:
10.1091/mbc.e05-07-0659. [PMID: 16597703] - Guoheng Xu, Carole Sztalryd, Constantine Londos. Degradation of perilipin is mediated through ubiquitination-proteasome pathway.
Biochimica et biophysica acta.
2006 Jan; 1761(1):83-90. doi:
10.1016/j.bbalip.2005.12.005. [PMID: 16448845] - Angela M Domitrovich, Daniel J Felmlee, Aleem Siddiqui. Hepatitis C virus nonstructural proteins inhibit apolipoprotein B100 secretion.
The Journal of biological chemistry.
2005 Dec; 280(48):39802-8. doi:
10.1074/jbc.m510391200. [PMID: 16203724] - Shizuko Tachibana, Kan Sato, Yoshitake Cho, Tomoyuki Chiba, Wolfgang J Schneider, Yukio Akiba. Octanoate reduces very low-density lipoprotein secretion by decreasing the synthesis of apolipoprotein B in primary cultures of chicken hepatocytes.
Biochimica et biophysica acta.
2005 Oct; 1737(1):36-43. doi:
10.1016/j.bbalip.2005.09.001. [PMID: 16226916] - Kasturi Pal, Charlotte S Kaetzel, Kathleen Brundage, Cynthia A Cunningham, Christopher F Cuff. Regulation of polymeric immunoglobulin receptor expression by reovirus.
The Journal of general virology.
2005 Aug; 86(Pt 8):2347-2357. doi:
10.1099/vir.0.80690-0. [PMID: 16033983] - Min Hong, Mingqing Li, Changhui Mao, Amy S Lee. Endoplasmic reticulum stress triggers an acute proteasome-dependent degradation of ATF6.
Journal of cellular biochemistry.
2004 Jul; 92(4):723-32. doi:
10.1002/jcb.20118. [PMID: 15211570] - Jun Hee Lim, Young-Chae Chang, Yong Bok Park, Jong-Wook Park, Taeg Kyu Kwon. Transcriptional repression of E2F gene by proteasome inhibitors in human osteosarcoma cells.
Biochemical and biophysical research communications.
2004 Jun; 318(4):868-72. doi:
10.1016/j.bbrc.2004.04.103. [PMID: 15147952] - Stephanie Tissier, Steve Lancel, Xavier Marechal, Serge Mordon, Florence Depontieu, Arnaud Scherpereel, Claude Chopin, Remi Neviere. Calpain inhibitors improve myocardial dysfunction and inflammation induced by endotoxin in rats.
Shock (Augusta, Ga.).
2004 Apr; 21(4):352-7. doi:
10.1097/00024382-200404000-00010. [PMID: 15179136] - Louis R Lapierre, Deborah L Currie, Zemin Yao, Jianjun Wang, Roger S McLeod. Amino acid sequences within the beta1 domain of human apolipoprotein B can mediate rapid intracellular degradation.
Journal of lipid research.
2004 Feb; 45(2):366-77. doi:
10.1194/jlr.m300104-jlr200. [PMID: 14581578] - Sumiko Abe-Dohmae, Yuika Ikeda, Michinori Matsuo, Michi Hayashi, Kei-ichiro Okuhira, Kazumitsu Ueda, Shinji Yokoyama. Human ABCA7 supports apolipoprotein-mediated release of cellular cholesterol and phospholipid to generate high density lipoprotein.
The Journal of biological chemistry.
2004 Jan; 279(1):604-11. doi:
10.1074/jbc.m309888200. [PMID: 14570867] - M Zoltowska, E Ziv, E Delvin, M Lambert, E Seidman, E Levy. Both insulin resistance and diabetes in Psammomys obesus upregulate the hepatic machinery involved in intracellular VLDL assembly.
Arteriosclerosis, thrombosis, and vascular biology.
2004 Jan; 24(1):118-23. doi:
10.1161/01.atv.0000105901.18785.99. [PMID: 14604833] - Baukje M Elzinga, Julius F W Baller, Arjen R Mensenkamp, Zemin Yao, Luis B Agellon, Folkert Kuipers, Henkjan J Verkade. Inhibition of apolipoprotein B secretion by taurocholate is controlled by the N-terminal end of the protein in rat hepatoma McArdle-RH7777 cells.
Biochimica et biophysica acta.
2003 Dec; 1635(2-3):93-103. doi:
10.1016/j.bbalip.2003.10.009. [PMID: 14729072] - David S Paul, Anne W Harmon, Courtney P Winston, Yashomati M Patel. Calpain facilitates GLUT4 vesicle translocation during insulin-stimulated glucose uptake in adipocytes.
The Biochemical journal.
2003 Dec; 376(Pt 3):625-32. doi:
10.1042/bj20030681. [PMID: 12974673] - Yusuke Higashi, Hiroyuki Itabe, Hironaga Fukase, Masahiro Mori, Yasuyuki Fujimoto, Tatsuya Takano. Transmembrane lipid transfer is crucial for providing neutral lipids during very low density lipoprotein assembly in endoplasmic reticulum.
The Journal of biological chemistry.
2003 Jun; 278(24):21450-8. doi:
10.1074/jbc.m301376200. [PMID: 12670935] - C Rodriguez, B Raposo, J Martínez-González, V Llorente-Cortés, G Vilahur, L Badimon. Modulation of ERG25 expression by LDL in vascular cells.
Cardiovascular research.
2003 Apr; 58(1):178-85. doi:
10.1016/s0008-6363(02)00856-8. [PMID: 12667960] - Nica M Borradaile, Linda E de Dreu, P Hugh R Barrett, Murray W Huff. Inhibition of hepatocyte apoB secretion by naringenin: enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters.
Journal of lipid research.
2002 Sep; 43(9):1544-54. doi:
10.1194/jlr.m200115-jlr200. [PMID: 12235187] - Saori Furuta, Fausto Ortiz, Xiu Zhu Sun, Hsiao-Huei Wu, Andrew Mason, Jamil Momand. Copper uptake is required for pyrrolidine dithiocarbamate-mediated oxidation and protein level increase of p53 in cells.
The Biochemical journal.
2002 Aug; 365(Pt 3):639-48. doi:
10.1042/bj20011251. [PMID: 11964141] - Reijiro Arakawa, Shinji Yokoyama. Helical apolipoproteins stabilize ATP-binding cassette transporter A1 by protecting it from thiol protease-mediated degradation.
The Journal of biological chemistry.
2002 Jun; 277(25):22426-9. doi:
10.1074/jbc.m202996200. [PMID: 11950847] - Winnie L Yee, Qi Wang, Trecito Agdinaoay, Kaohimanu Dang, Healani Chang, Andrew Grandinetti, Adrian A Franke, Andre Theriault. Green tea catechins decrease apolipoprotein B-100 secretion from HepG2 cells.
Molecular and cellular biochemistry.
2002 Jan; 229(1-2):85-92. doi:
10.1023/a:1017920527201. [PMID: 11936850] - A Musial, N T Eissa. Inducible nitric-oxide synthase is regulated by the proteasome degradation pathway.
The Journal of biological chemistry.
2001 Jun; 276(26):24268-73. doi:
10.1074/jbc.m100725200. [PMID: 11312270] - C Rodríguez, J Martínez-González, S Sánchez-Gómez, L Badimon. LDL downregulates CYP51 in porcine vascular endothelial cells and in the arterial wall through a sterol regulatory element binding protein-2-dependent mechanism.
Circulation research.
2001 Feb; 88(3):268-74. doi:
10.1161/01.res.88.3.268. [PMID: 11179193] - A Theriault, Q Wang, S C Van Iderstine, B Chen, A A Franke, K Adeli. Modulation of hepatic lipoprotein synthesis and secretion by taxifolin, a plant flavonoid.
Journal of lipid research.
2000 Dec; 41(12):1969-79. doi:
. [PMID: 11108730] - T Ravid, R Doolman, R Avner, D Harats, J Roitelman. The ubiquitin-proteasome pathway mediates the regulated degradation of mammalian 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
The Journal of biological chemistry.
2000 Nov; 275(46):35840-7. doi:
10.1074/jbc.m004793200. [PMID: 10964918] - B S Kang, O G French, J J Sando, C S Hahn. Activation-dependent degradation of protein kinase C eta.
Oncogene.
2000 Aug; 19(37):4263-72. doi:
10.1038/sj.onc.1203779. [PMID: 10980600] - K Ohkawa, T Asakura, K Takada, T Sawai, Y Hashizume, Y Okawa, N Yanaihara. Calpain inhibitor causes accumulation of ubiquitinated P-glycoprotein at the cell surface: possible role of calpain in P-glycoprotein turnover.
International journal of oncology.
1999 Oct; 15(4):677-86. doi:
10.3892/ijo.15.4.677. [PMID: 10493948] - J F Fleming, G M Spitsen, T Y Hui, L Olivier, E Z Du, M Raabe, R A Davis. Chinese hamster ovary cells require the coexpression of microsomal triglyceride transfer protein and cholesterol 7alpha-hydroxylase for the assembly and secretion of apolipoprotein B-containing lipoproteins.
The Journal of biological chemistry.
1999 Apr; 274(14):9509-14. doi:
10.1074/jbc.274.14.9509. [PMID: 10092635] - J S Kendrick, J A Higgins. Dietary fish oils inhibit early events in the assembly of very low density lipoproteins and target apoB for degradation within the rough endoplasmic reticulum of hamster hepatocytes.
Journal of lipid research.
1999 Mar; 40(3):504-14. doi:
10.1016/s0022-2275(20)32455-x. [PMID: 10064739] - Y T Chen, D B Stewart, W J Nelson. Coupling assembly of the E-cadherin/beta-catenin complex to efficient endoplasmic reticulum exit and basal-lateral membrane targeting of E-cadherin in polarized MDCK cells.
The Journal of cell biology.
1999 Feb; 144(4):687-99. doi:
10.1083/jcb.144.4.687. [PMID: 10037790] - R R Krishnamoorthy, M J Crawford, M M Chaturvedi, S K Jain, B B Aggarwal, M R Al-Ubaidi, N Agarwal. Photo-oxidative stress down-modulates the activity of nuclear factor-kappaB via involvement of caspase-1, leading to apoptosis of photoreceptor cells.
The Journal of biological chemistry.
1999 Feb; 274(6):3734-43. doi:
10.1074/jbc.274.6.3734. [PMID: 9920926] - A L White, B Guerra, J Wang, R E Lanford. Presecretory degradation of apolipoprotein [a] is mediated by the proteasome pathway.
Journal of lipid research.
1999 Feb; 40(2):275-86. doi:
10.1016/s0022-2275(20)33367-8. [PMID: 9925657] - A Kamal, Y Ying, R G Anderson. Annexin VI-mediated loss of spectrin during coated pit budding is coupled to delivery of LDL to lysosomes.
The Journal of cell biology.
1998 Aug; 142(4):937-47. doi:
10.1083/jcb.142.4.937. [PMID: 9722607] - S Taya, T Yamamoto, K Kano, Y Kawano, A Iwamatsu, T Tsuchiya, K Tanaka, M Kanai-Azuma, S A Wood, J S Mattick, K Kaibuchi. The Ras target AF-6 is a substrate of the fam deubiquitinating enzyme.
The Journal of cell biology.
1998 Aug; 142(4):1053-62. doi:
10.1083/jcb.142.4.1053. [PMID: 9722616] - S Hashemolhosseini, Y Nagamine, S J Morley, S Desrivières, L Mercep, S Ferrari. Rapamycin inhibition of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability.
The Journal of biological chemistry.
1998 Jun; 273(23):14424-9. doi:
10.1074/jbc.273.23.14424. [PMID: 9603954] - Y Q Liang, M Kinoshita, T Muto, Y Fujimaki, N Matsuki, H Saito, M Yamanaka, T Teramoto. Defect in an intrahepatic degradation of apolipoprotein B in suncus: an animal model of hypobetalipoproteinemia.
Journal of biochemistry.
1998 Jan; 123(1):28-32. doi:
10.1093/oxfordjournals.jbchem.a021912. [PMID: 9504405] - J Macri, K Adeli. Conformational changes in apolipoprotein B modulate intracellular assembly and degradation of ApoB-containing lipoprotein particles in HepG2 cells.
Arteriosclerosis, thrombosis, and vascular biology.
1997 Nov; 17(11):2982-94. doi:
10.1161/01.atv.17.11.2982. [PMID: 9409285] - K T Bush, A L Goldberg, S K Nigam. Proteasome inhibition leads to a heat-shock response, induction of endoplasmic reticulum chaperones, and thermotolerance.
The Journal of biological chemistry.
1997 Apr; 272(14):9086-92. doi:
10.1074/jbc.272.14.9086. [PMID: 9083035] - S R Schow, A Joly. N-acetyl-leucinyl-leucinyl-norleucinal inhibits lipopolysaccharide-induced NF-kappaB activation and prevents TNF and IL-6 synthesis in vivo.
Cellular immunology.
1997 Feb; 175(2):199-202. doi:
10.1006/cimm.1996.1061. [PMID: 9023426] - M F Ingram, G S Shelness. Apolipoprotein B-100 destined for lipoprotein assembly and intracellular degradation undergoes efficient translocation across the endoplasmic reticulum membrane.
Journal of lipid research.
1996 Oct; 37(10):2202-14. doi:
". [PMID: 8906597] - F Benoist, E Nicodeme, T Grand-Perret. Microsomal triacylglycerol transfer protein prevents presecretory degradation of apolipoprotein B-100. A dithiothreitol-sensitive protease is involved.
European journal of biochemistry.
1996 Sep; 240(3):713-20. doi:
10.1111/j.1432-1033.1996.0713h.x. [PMID: 8856075] - M J Borgnia, G D Eytan, Y G Assaraf. Competition of hydrophobic peptides, cytotoxic drugs, and chemosensitizers on a common P-glycoprotein pharmacophore as revealed by its ATPase activity.
The Journal of biological chemistry.
1996 Feb; 271(6):3163-71. doi:
10.1074/jbc.271.6.3163. [PMID: 8621716] - E J Murray, K K Tram, S S Murray, D B Lee. Parathyroid hormone-induced retraction of MC3T3-E1 osteoblastic cells is attenuated by the calpain inhibitor N-Ac-Leu-Leu-norleucinal.
Metabolism: clinical and experimental.
1995 Feb; 44(2):141-4. doi:
10.1016/0026-0495(95)90254-6. [PMID: 7869906] - N Sakata, X Wu, J L Dixon, H N Ginsberg. Proteolysis and lipid-facilitated translocation are distinct but competitive processes that regulate secretion of apolipoprotein B in Hep G2 cells.
The Journal of biological chemistry.
1993 Nov; 268(31):22967-70. doi:
. [PMID: 8226809] - T B Shea, M L Beermann, R A Nixon. Multiple proteases regulate neurite outgrowth in NB2a/dl neuroblastoma cells.
Journal of neurochemistry.
1991 Mar; 56(3):842-51. doi:
10.1111/j.1471-4159.1991.tb02000.x. [PMID: 1993897]
