Estradiol dipropionate (BioDeep_00000858770)
Volatile Flavor Compounds
代谢物信息卡片
化学式: C24H32O4 (384.2300472)
中文名称: 二丙酸雌二醇
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC(=O)OC1CCC2C1(CCC3C2CCC4=C3C=CC(=C4)OC(=O)CC)C
InChI: InChI=1S/C24H32O4/c1-4-22(25)27-16-7-9-17-15(14-16)6-8-19-18(17)12-13-24(3)20(19)10-11-21(24)28-23(26)5-2/h7,9,14,18-21H,4-6,8,10-13H2,1-3H3/t18-,19-,20+,21+,24+/m1/s1
描述信息
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C483 - Therapeutic Estrogen
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
同义名列表
2 个代谢物同义名
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:31560
- KEGGdrug: D01617
- PubChem: 8225
- ChEMBL: CHEMBL1697791
- CAS: 113-38-2
- KEGG: C13077
- PubChem: 585141
- KNApSAcK: 31560
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964
. [PMID: 31515284] - Svetlana Trifunović, Milica Manojlović-Stojanoski, Nataša Ristić, Nataša Nestorović, Ivana Medigović, Jasmina Živanović, Verica Milošević. Changes of growth hormone-releasing hormone and somatostatin neurons in the rat hypothalamus induced by genistein: a stereological study.
Nutritional neuroscience.
2016 Dec; 19(10):467-474. doi:
10.1179/1476830514y.0000000143
. [PMID: 25087680] - B Šošić-Jurjević, B Filipović, K Renko, M Miler, S Trifunović, V Ajdžanovič, J Kӧhrle, V Milošević. Testosterone and estradiol treatments differently affect pituitary-thyroid axis and liver deiodinase 1 activity in orchidectomized middle-aged rats.
Experimental gerontology.
2015 Dec; 72(?):85-98. doi:
10.1016/j.exger.2015.09.010
. [PMID: 26384168] - Svetlana Trifunović, Milica Manojlović-Stojanoski, Vladimir Ajdžanović, Nataša Nestorović, Nataša Ristić, Branka Sošić-Jurjević, Verica Milošević. Soy extract-dependent changes in morphofunctional parameters of the pituitary corticotropes in adult rats.
Acta histochemica.
2014 Jun; 116(5):717-22. doi:
10.1016/j.acthis.2013.12.010
. [PMID: 24485333] - Michiko Noguchi, Shinsuke Kashiwai, Seigo Itoh, Hanako Okumura, Katsumasa Kure, Chie Suzuki, Koji Yoshioka. Reproductive hormone profiles in sows on estrus synchronization using estradiol dipropionate and prostaglandin F(2α)-analogue and the reproductive performance in female pigs on commercial farms.
The Journal of veterinary medical science.
2013; 75(3):343-8. doi:
10.1292/jvms.12-0022
. [PMID: 23131781] - Ivan Sabolic, Ivana Vrhovac, Daniela Balen Eror, Maria Gerasimova, Michael Rose, Davorka Breljak, Marija Ljubojevic, Hrvoje Brzica, Anne Sebastiani, Serge C Thal, Christoph Sauvant, Helmut Kipp, Volker Vallon, Hermann Koepsell. Expression of Na+-D-glucose cotransporter SGLT2 in rodents is kidney-specific and exhibits sex and species differences.
American journal of physiology. Cell physiology.
2012 Apr; 302(8):C1174-88. doi:
10.1152/ajpcell.00450.2011
. [PMID: 22262063] - Michiko Noguchi, Koji Yoshioka, Chie Suzuki, Seigo Itoh, Hiroyuki Kaneko. An efficient protocol for inducing pseudopregnancy using estradiol dipropionate and follicular development associated with changes in reproductive hormones after prostaglandin F2alpha treatment in pseudopregnant sows.
Reproductive biology and endocrinology : RB&E.
2011 Dec; 9(?):157. doi:
10.1186/1477-7827-9-157
. [PMID: 22168485] - Michiko Noguchi, Koji Yoshioka, Chie Suzuki, Sachiko Arai, Seigo Itoh, Yasunori Wada. Estrus synchronization with pseudopregnant gilts induced by a single treatment of estradiol dipropionate.
The Journal of reproduction and development.
2010 Aug; 56(4):421-7. doi:
10.1262/jrd.10-006t
. [PMID: 20484869] - Jiro Miyajima, Tokumasa Hayashi, Koujiro Saito, Shizuka Iida, Kei Matsuoka. The Interaction between female sex hormone receptors and osteopontin in a rat hyperoxaluric model.
The Kurume medical journal.
2010; 57(3):73-80. doi:
10.2739/kurumemedj.57.73
. [PMID: 21186342] - Hrvoje Brzica, Davorka Breljak, Wolfgang Krick, Mila Lovrić, Gerhard Burckhardt, Birgitta C Burckhardt, Ivan Sabolić. The liver and kidney expression of sulfate anion transporter sat-1 in rats exhibits male-dominant gender differences.
Pflugers Archiv : European journal of physiology.
2009 Apr; 457(6):1381-92. doi:
10.1007/s00424-008-0611-5
. [PMID: 19002488] - B Sosić-Jurjević, B Filipović, V Milosević, N Nestorović, N Negić, M Sekulić. Effects of ovariectomy and chronic estradiol administration on pituitary-thyroid axis in adult rats.
Life sciences.
2006 Jul; 79(9):890-7. doi:
10.1016/j.lfs.2006.03.001
. [PMID: 16584751] - Branka Sosić-Jurjević, Branko Filipović, Verica Milosević, Natasa Nestorović, Milica Manojlović-Stojanoski, Branislava Brkić, Milka Sekulić. Chronic estradiol exposure modulates thyroid structure and decreases T4 and T3 serum levels in middle-aged female rats.
Hormone research.
2005; 63(1):48-54. doi:
10.1159/000083139
. [PMID: 15637454] - A G Gunin, A D Bitter, A B Demakov, E N Vasilieva, N V Suslonova. Effects of peroxisome proliferator activated receptors-alpha and -gamma agonists on estradiol-induced proliferation and hyperplasia formation in the mouse uterus.
The Journal of endocrinology.
2004 Aug; 182(2):229-39. doi:
10.1677/joe.0.1820229
. [PMID: 15283683] - J G Lemmen, R J Arends, A L van Boxtel, P T van der Saag, B van der Burg. Tissue- and time-dependent estrogen receptor activation in estrogen reporter mice.
Journal of molecular endocrinology.
2004 Jun; 32(3):689-701. doi:
10.1677/jme.0.0320689
. [PMID: 15171709] - B Filipović, B Sosić-Jurjević, N Nestorović, M Manojlović Stojanoski, N Kostić, V Milosević, M Sekulić. The thyroid C cells of ovariectomized rats treated with estradiol.
Histochemistry and cell biology.
2003 Nov; 120(5):409-14. doi:
10.1007/s00418-003-0578-4
. [PMID: 14564528] - Ryota Ohashi, Motoi Sugimura, Naohiro Kanayama. Estrogen administration enhances thrombin generation in rats.
Thrombosis research.
2003; 112(5-6):325-8. doi:
10.1016/j.thromres.2003.11.014
. [PMID: 15041278] - M V Mosiagina, I V Kuznetsova, O V Zelennikov, P E Garlov. [Morpho-functional analysis of the steroid-producing cells in pink salmon fry gonads Oncorhynhus gorbuscha (Walbaum) in normal condition and after estradiol treatment].
Tsitologiia.
2003; 45(5):450-5. doi:
"
. [PMID: 14521052] - K Yamaguchi, H Honda, C Wakisaka, A Tohei, H Kogo. Effects of phytoestrogens on acetylcholine- and isoprenaline-induced vasodilation in rat aorta.
Japanese journal of pharmacology.
2001 Sep; 87(1):67-73. doi:
10.1254/jjp.87.67
. [PMID: 11676200] - A G Gunin, I N Mashin, D A Zakharov. Proliferation, mitosis orientation and morphogenetic changes in the uterus of mice following chronic treatment with both estrogen and glucocorticoid hormones.
The Journal of endocrinology.
2001 Apr; 169(1):23-31. doi:
10.1677/joe.0.1690023
. [PMID: 11250643] - S Ohmori, K Kanda, S Kawano, F Kambe, H Seo. Changes in calcium, PTH and 1,25(OH)2 vitamin D3 during tail-suspension in ovariectomized rats: effects of estrogen administration.
Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University.
2000 Dec; 44(2):75-8. doi:
. [PMID: 12353529]
- S Kawano, F Kambe, S Ohmori, K Kanda, T Nagaya, H Seo. Effect of estrogen and tail-suspension on expression of osteocalcin mRNA in femur of ovariectomized rats.
Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University.
2000 Dec; 44(2):82-4. doi:
. [PMID: 12353530]
- M Lovren, M Sekulić, V Milosević, M Mićić, N Radulović. Effects of estradiol and calcium on gonadotrophic cells in middle-aged female rats.
The Histochemical journal.
1999 Oct; 31(10):671-6. doi:
10.1023/a:1003899620578
. [PMID: 10576416] - M Sekulić, M Lovren, V Milosević. Immunoreactive TSH cells in the pituitary of female middle-aged rats after treatment with estradiol or calcium.
Acta histochemica.
1998 Apr; 100(2):185-91. doi:
10.1016/s0065-1281(98)80026-3
. [PMID: 9587629] - M Sekulić, M Lovren, V Milosević, M Mićić, L Balint-Perić. Thyroid C cells of middle-aged rats treated with estradiol or calcium.
Histochemistry and cell biology.
1998 Mar; 109(3):257-62. doi:
10.1007/s004180050225
. [PMID: 9541474] - M Akishita, Y Ouchi, H Miyoshi, A Orimo, K Kozaki, M Eto, M Ishikawa, S Kim, K Toba, H Orimo. Estrogen inhibits endothelin-1 production and c-fos gene expression in rat aorta.
Atherosclerosis.
1996 Aug; 125(1):27-38. doi:
10.1016/0021-9150(96)05836-4
. [PMID: 8831924] - M Sekulić, M Lovren, T Popović. Estradiol-induced changes in TSH-like immunoreactivity of pituitary cells in female rats.
Experientia.
1995 Apr; 51(4):335-8. doi:
10.1007/bf01928890
. [PMID: 7729499] - T Kubota, K Ishibiki, O Abe, H Kosano, N Ohsawa, R M Hoffman. Mode of action of estra-1,3,5(10)-triene-3, 17 beta-diol, 3-benzoate, 17[4-[4-[bis(2-chloroethyl)amino]phenyl]-1-oxobutoxy] acetate] (KM2210) on MCF-7 human breast tumours transplanted into nude mice.
Anticancer research.
1993 Jul; 13(4):935-40. doi:
NULL
. [PMID: 8352562] - P Navarra, W Eechaute, P Preziosi, E Lacroix. Idazoxan inhibits hyperprolactinaemia in ovariectomized estrogen-treated rats.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
1991 Jan; 23(1):22-4. doi:
10.1055/s-2007-1003602
. [PMID: 2016076] - Y A Bogdarin. Effect of estrogen-receptor interaction on the levels of fatty acid-binding proteins and spectra of free acids in small intestinal mucosa of rabbits.
Experimental and clinical endocrinology.
1990 Nov; 96(2):177-84. doi:
10.1055/s-0029-1211007
. [PMID: 2097162] - A O Prakash, A Mathur, H Mehta, R Mathur. Concentrations of Na+ and K+ in serum and uterine flushings of ovariectomized, pregnant and cyclic rats when treated with extracts of Hibiscus rosa sinensis flowers.
Journal of ethnopharmacology.
1990 Mar; 28(3):337-47. doi:
10.1016/0378-8741(90)90085-8
. [PMID: 2335962] - R K Tewari, S Pathak, A O Prakash. Biochemical and histological studies of reproductive organs in cyclic and ovariectomized rats supporting a non-hormonal action for neem oil.
Journal of ethnopharmacology.
1989 May; 25(3):281-93. doi:
10.1016/0378-8741(89)90034-2
. [PMID: 2747262] - G Iu Chemeris. [Effect of sex hormones on the induction of renal capsule angiosarcomas in mice].
Eksperimental'naia onkologiia.
1989; 11(2):71-2. doi:
NULL
. [PMID: 2737135] - K S Chertkov, O M Atamanova, M F Sbitneva, G V Katsiia, Z M Mosina. [Effect of estradiol dipropionate on hemopoiesis and the steroid hormone concentration of the blood plasma in dogs].
Patologicheskaia fiziologiia i eksperimental'naia terapiia.
1988 Sep; ?(5):35-9. doi:
NULL
. [PMID: 3217151] - A O Prakash, R K Tewari, R Mathur. Non-hormonal post-coital contraceptive action of neem oil in rats.
Journal of ethnopharmacology.
1988 May; 23(1):53-9. doi:
10.1016/0378-8741(88)90114-6
. [PMID: 3419204] - S Soback, G Ziv, E Bogin, Z Cohen, Y Earon. Pharmacokinetic changes of several antibiotics in chickens during induced fatty liver.
Research in veterinary science.
1987 Jul; 43(1):49-54. doi:
10.1016/s0034-5288(18)30740-9
. [PMID: 3628983] - M Fujimoto, E Yoshino, K Hirakawa, K Chihara, Y Ibata. Studies on estrogen induced pituitary tumor in the rat with special reference to the relationship of the tuberoinfundibular dopamine neuron system.
Journal of neuro-oncology.
1987; 5(2):151-9. doi:
10.1007/bf02571303
. [PMID: 3668610] - K R Bruce, P A Anastassiadis. Monosaccharide composition of the serum of normal and estrogen-treated male birds.
Poultry science.
1985 Dec; 64(12):2377-82. doi:
10.3382/ps.0642377
. [PMID: 4095070] - A Brenes, L S Jensen, K Takahashi, S L Bolden. Dietary effects on content of hepatic lipid, plasma minerals, and tissue ascorbic acid in hens and estrogenized chicks.
Poultry science.
1985 May; 64(5):947-54. doi:
10.3382/ps.0640947
. [PMID: 4001076] - C X Mendonca, K Takahashi, L S Jensen. Effect of fractions of fish meal and hepatic lipid deposition in estrogenized chicks.
Poultry science.
1984 May; 63(5):1020-6. doi:
10.3382/ps.0631020
. [PMID: 6728789] - S L Bolden, L S Jensen, K Takahashi. Responses in calcium and phosphorus metabolism and hepatic lipid deposition among estrogenized chicks fed various dietary ingredients.
The Journal of nutrition.
1984 Mar; 114(3):591-7. doi:
10.1093/jn/114.3.591
. [PMID: 6699740] - Y Akiba, K Takahashi, T Matsumoto. Effect of diisopropyl 1,3-dithiolan-2-ylidenemalonate on experimental fatty livers in chicks.
Poultry science.
1984 Jan; 63(1):117-22. doi:
10.3382/ps.0630117
. [PMID: 6701137] - Y Akiba, L S Jensen, C X Mendonca. Laboratory model with chicks for assay of nutritional factors affecting hepatic lipid accumulation in laying hens.
Poultry science.
1983 Jan; 62(1):143-51. doi:
10.3382/ps.0620143
. [PMID: 6828406] - A K Dasmahapatra, A K Medda. Effect of estradiol dipropionate and testosterone propionate on the glycogen, lipid, and water contents of liver, muscle, and gonad of male and female (vitellogenic and nonvitellogenic) Singi fish (Heteropneustes fossilis Bloch).
General and comparative endocrinology.
1982 Dec; 48(4):476-84. doi:
10.1016/0016-6480(82)90183-6
. [PMID: 7160613] - A K Dasmahapatra, A K Ray, A K Medda. Temperature dependent action of estrogen in Singi fish (Heteropneustes fossilis Bloch).
Endokrinologie.
1981 Oct; 78(1):107-10. doi:
NULL
. [PMID: 7318770] - T Lahiri, J R Chowdhury. Lipid patterns in vaginal cells exfoliated from different physiologic conditions.
Acta cytologica.
1981 Sep; 25(5):572-7. doi:
"
. [PMID: 6945023] - S H Sedrant, T G Taylor, M Akhtar. The regulation of 25-hydroxycholecalciferol metabolism in the kidney of Japanese quail (Coturnix coturnix japonica) by sex hormones and by parathyroid extract.
General and comparative endocrinology.
1981 Aug; 44(4):514-23. doi:
10.1016/0016-6480(81)90340-3
. [PMID: 6973503] - S M Ventura, S L Dachtler. Effects of sex hormones on hepatic aldehyde oxidase activity in C57BL/6J mice.
Hormone research.
1981; 14(4):250-9. doi:
10.1159/000179395
. [PMID: 7308982] - M J Curtis, A W Pearson, E J Butler. Bacterial endotoxins and liver haemorrhage in the oestrogenised chicken.
Research in veterinary science.
1980 Nov; 29(3):378-82. doi:
10.1016/s0034-5288(18)32646-8
. [PMID: 7020014] - B M DORAN, M E GREGORY. THE INFLUENCE OF OVARIAN ACTIVITY OR TREATMENT WITH OESTRADIOL DIPROPIONATE ON THE VITAMIN B 12 CONTENT OF CELLS AND PLASMA OF THE BLOOD OF THE DOMESTIC FOWL.
The British journal of nutrition.
1963; 17(?):583-90. doi:
10.1079/bjn19630061
. [PMID: 14086503] - U JAHN. [Karyometric study of the effect of testosterone propionate, estradiol dipropionate and thyroxin on the cell nuclei of Class I convoluted tubules of rat kidneys].
Endokrinologie.
1955 Jul; 32(5-6):302-9. doi:
NULL
. [PMID: 13261963] - R J MERKLIN. A histochemical study of male mice injected with estradiol dipropionate before puberty.
The Anatomical record.
1955 Jun; 122(2):257-70. doi:
10.1002/ar.1091220210
. [PMID: 13238858] - W BOLTON. The effect of injections of oestradiol dipropionate into immature pullets upon the manganese content of the blood plasma and of some tissues.
The British journal of nutrition.
1955; 9(2):170-3. doi:
10.1079/bjn19550024
. [PMID: 14389634]