2-Amino-2-Deoxy-Hexose (BioDeep_00000840443)

   


代谢物信息卡片


2-Amino-2-Deoxy-Hexose

化学式: C6H13NO5 (179.0793688)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C1C(C(C(C(O1)O)N)O)O)O
InChI: InChI=1S/C6H13NO5/c7-3-5(10)4(9)2(1-8)12-6(3)11/h2-6,8-11H,1,7H2

描述信息

同义名列表

1 个代谢物同义名

2-Amino-2-Deoxy-Hexose



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(8)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Mazlyzam Abdul Latif, Asrul Mustafa, Lee Chee Keong, Asmah Hamid. Chromolaena odorata layered-nitrile rubber polymer transdermal patch enhanced wound healing in vivo. PloS one. 2024; 19(3):e0295381. doi: 10.1371/journal.pone.0295381. [PMID: 38466676]
  • Yi Zou, Zongkai Liu, Wenjia Liu, Zhaidong Liu. Current knowledge and potential intervention of hexosamine biosynthesis pathway in lung cancer. World journal of surgical oncology. 2023 Oct; 21(1):334. doi: 10.1186/s12957-023-03226-z. [PMID: 37880766]
  • Yanmin Gao, Yanli Ma, Di Xie, Hua Jiang. ManNAc protects against podocyte pyroptosis via inhibiting mitochondrial damage and ROS/NLRP3 signaling pathway in diabetic kidney injury model. International immunopharmacology. 2022 Jun; 107(?):108711. doi: 10.1016/j.intimp.2022.108711. [PMID: 35338958]
  • Leire Pedrosa, Carles Foguet, Helena Oliveres, Iván Archilla, Marta García de Herreros, Adela Rodríguez, Antonio Postigo, Daniel Benítez-Ribas, Jordi Camps, Miriam Cuatrecasas, Antoni Castells, Aleix Prat, Timothy M Thomson, Joan Maurel, Marta Cascante. A novel gene signature unveils three distinct immune-metabolic rewiring patterns conserved across diverse tumor types and associated with outcomes. Frontiers in immunology. 2022; 13(?):926304. doi: 10.3389/fimmu.2022.926304. [PMID: 36119118]
  • Nuria Carrillo, May C Malicdan, Petcharat Leoyklang, Joseph A Shrader, Galen Joe, Christina Slota, John Perreault, John D Heiss, Bradley Class, Chia-Ying Liu, Kennan Bradley, Colleen Jodarski, Carla Ciccone, Claire Driscoll, Rebecca Parks, Scott Van Wart, Levent Bayman, Christopher S Coffey, Melanie Quintana, Scott M Berry, Marjan Huizing, William A Gahl. Safety and efficacy of N-acetylmannosamine (ManNAc) in patients with GNE myopathy: an open-label phase 2 study. Genetics in medicine : official journal of the American College of Medical Genetics. 2021 11; 23(11):2067-2075. doi: 10.1038/s41436-021-01259-x. [PMID: 34257421]
  • Laura Morelli, Luigi Lay, Darielys Santana-Mederos, Yury Valdes-Balbin, Vicente Verez Bencomo, Angela van Diepen, Cornelis H Hokke, Fabrizio Chiodo, Federica Compostella. Glycan Array Evaluation of Synthetic Epitopes between the Capsular Polysaccharides from Streptococcus pneumoniae 19F and 19A. ACS chemical biology. 2021 09; 16(9):1671-1679. doi: 10.1021/acschembio.1c00347. [PMID: 34469105]
  • Scott Van Wart, Donald E Mager, Cindy J Bednasz, Marjan Huizing, Nuria Carrillo. Population Pharmacokinetic Model of N-acetylmannosamine (ManNAc) and N-acetylneuraminic acid (Neu5Ac) in Subjects with GNE Myopathy. Drugs in R&D. 2021 Jun; 21(2):189-202. doi: 10.1007/s40268-021-00343-6. [PMID: 33893973]
  • Martha Robles-Flores, Angela P Moreno-Londoño, M Cristina Castañeda-Patlán. Signaling Pathways Involved in Nutrient Sensing Control in Cancer Stem Cells: An Overview. Frontiers in endocrinology. 2021; 12(?):627745. doi: 10.3389/fendo.2021.627745. [PMID: 33828530]
  • Federico Fuentes, Nuria Carrillo, Kenneth J Wilkins, Jodi Blake, Petcharat Leoyklang, William A Gahl, Jeffrey B Kopp, Marjan Huizing. Elevated plasma free sialic acid levels in individuals with reduced glomerular filtration rates. Kidney360. 2020 09; 1(9):957-961. doi: 10.34067/kid.0002122020. [PMID: 33969317]
  • Naveen Vankadari. Structure of Furin Protease Binding to SARS-CoV-2 Spike Glycoprotein and Implications for Potential Targets and Virulence. The journal of physical chemistry letters. 2020 Aug; 11(16):6655-6663. doi: 10.1021/acs.jpclett.0c01698. [PMID: 32787225]
  • Ângela R Guerra, Ana F Paulino, Maria M Castro, Helena Oliveira, Maria F Duarte, Iola F Duarte. Triple Negative Breast Cancer and Breast Epithelial Cells Differentially Reprogram Glucose and Lipid Metabolism upon Treatment with Triterpenic Acids. Biomolecules. 2020 08; 10(8):. doi: 10.3390/biom10081163. [PMID: 32784479]
  • Daping Cui, Dewei Zhao, Shibo Huang. Structural characterization of a safflower polysaccharide and its promotion effect on steroid-induced osteonecrosis in vivo. Carbohydrate polymers. 2020 Apr; 233(?):115856. doi: 10.1016/j.carbpol.2020.115856. [PMID: 32059907]
  • Marc C Daniels, Donald A McClain, Errol D Crook. Transcriptional Regulation of Transforming Growth Factor β1 by Glucose: Investigation into the Role of the Hexosamine Biosynthesis Pathway. The American journal of the medical sciences. 2020 02; 359(2):79-83. doi: 10.1016/j.amjms.2019.12.013. [PMID: 32039769]
  • Petra Kranaster, Christiaan Karreman, Jeremias E G A Dold, Alice Krebs, Melina Funke, Anna-Katharina Holzer, Stefanie Klima, Johanna Nyffeler, Stefan Helfrich, Valentin Wittmann, Marcel Leist. Time and space-resolved quantification of plasma membrane sialylation for measurements of cell function and neurotoxicity. Archives of toxicology. 2020 02; 94(2):449-467. doi: 10.1007/s00204-019-02642-z. [PMID: 31828357]
  • Hugo A Laviada-Molina, Irene Leal-Berumen, Ernesto Rodriguez-Ayala, Raul A Bastarrachea. Working Hypothesis for Glucose Metabolism and SARS-CoV-2 Replication: Interplay Between the Hexosamine Pathway and Interferon RF5 Triggering Hyperinflammation. Role of BCG Vaccine?. Frontiers in endocrinology. 2020; 11(?):514. doi: 10.3389/fendo.2020.00514. [PMID: 32733388]
  • Da Eun Lee, Su Jin Lee, Su Ji Kim, Hyun-Shik Lee, Oh-Shin Kwon. Curcumin Ameliorates Nonalcoholic Fatty Liver Disease through Inhibition of O-GlcNAcylation. Nutrients. 2019 Nov; 11(11):. doi: 10.3390/nu11112702. [PMID: 31717261]
  • Ismet Burcu Turkyilmaz, Zeynep Mine Coskun, Sema Bolkent, Refiye Yanardag. The effects of antioxidant combination on indomethacin-induced gastric mucosal injury in rats. Cellular and molecular biology (Noisy-le-Grand, France). 2019 Mar; 65(3):76-83. doi: . [PMID: 30942158]
  • Daping Cui, Dewei Zhao, Shibo Huang. Beneficial contribution of a safflower (Carthamus tinctorius L.) polysaccharide on steroid-induced avascular necrosis of the femoral head in rats. International journal of biological macromolecules. 2019 Feb; 123(?):581-586. doi: 10.1016/j.ijbiomac.2018.11.046. [PMID: 30419325]
  • Emmanuel Maes, Irina Sadovskaya, Mathilde Lévêque, Elisabeth Elass-Rochard, Bruno Payré, Thierry Grard, Vassilia Théodorou, Yann Guérardel, Muriel Mercier-Bonin. Structure and biological activities of a hexosamine-rich cell wall polysaccharide isolated from the probiotic Lactobacillus farciminis. Glycoconjugate journal. 2019 02; 36(1):39-55. doi: 10.1007/s10719-018-09854-y. [PMID: 30637506]
  • Jésica Flores-Martín, Luciana Reyna, Mariano Cruz Del Puerto, María L Rojas, Graciela M Panzetta-Dutari, Susana Genti-Raimondi. Hexosamine pathway regulates StarD7 expression in JEG-3 cells. Molecular biology reports. 2018 Dec; 45(6):2593-2600. doi: 10.1007/s11033-018-4428-9. [PMID: 30315445]
  • Komal M Parmar, Priyanka R Shende, Nitin Katare, Mahaveer Dhobi, Satyendra K Prasad. Wound healing potential of Solanum xanthocarpum in streptozotocin-induced diabetic rats. The Journal of pharmacy and pharmacology. 2018 Oct; 70(10):1389-1400. doi: 10.1111/jphp.12975. [PMID: 29984407]
  • Tae Sup Lee, Young Kim, Weiqi Zhang, In Ho Song, Ching-Hsuan Tung. Facile metabolic glycan labeling strategy for exosome tracking. Biochimica et biophysica acta. General subjects. 2018 May; 1862(5):1091-1100. doi: 10.1016/j.bbagen.2018.02.001. [PMID: 29410228]
  • Xin Xu, Amy Q Wang, Lea L Latham, Frank Celeste, Carla Ciccone, May Christine Malicdan, Barry Goldspiel, Pramod Terse, James Cradock, Nora Yang, Selwyn Yorke, John C McKew, William A Gahl, Marjan Huizing, Nuria Carrillo. Safety, pharmacokinetics and sialic acid production after oral administration of N-acetylmannosamine (ManNAc) to subjects with GNE myopathy. Molecular genetics and metabolism. 2017 09; 122(1-2):126-134. doi: 10.1016/j.ymgme.2017.04.010. [PMID: 28641925]
  • Marie Pantaleon, Sarah E Steane, Kathryn McMahon, James S M Cuffe, Karen M Moritz. Placental O-GlcNAc-transferase expression and interactions with the glucocorticoid receptor are sex specific and regulated by maternal corticosterone exposure in mice. Scientific reports. 2017 05; 7(1):2017. doi: 10.1038/s41598-017-01666-8. [PMID: 28515473]
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  • Yoon Jeong Choi, Nayoung Kim, Ju Yup Lee, Ryoung Hee Nam, Ji Hyung Seo, Seonmin Lee, Hee Jin Kim, Yoon Jin Choi, Hye Seung Lee, Dong Ho Lee. Gastroprotective Effects of PMK-S005 against Ethanol-Induced Acute Gastric Damage in Rats. Gut and liver. 2016 May; 10(3):348-55. doi: 10.5009/gnl14509. [PMID: 26347516]
  • Mazlyzam Abdul Latif, Mohd Zulasyraf Mohd Zaki, Tai May Leng, Noor Hidayah Abdul Rahman, Siti Aisyah Arshad, Asmah Hamid. Alocasia denudata Engler treatment enhance open wound healing activities in Wistar rat's skin. Journal of ethnopharmacology. 2015 Dec; 176(?):258-67. doi: 10.1016/j.jep.2015.10.036. [PMID: 26519202]
  • Yifan Shi, Xin Xu, Meng Fang, Michael Zhang, Yinghe Li, Brad Gillespie, Selwyn Yorke, Nora Yang, John C McKew, William A Gahl, Marjan Huizing, Nuria Carrillo-Carrasco, Amy Qiu Wang. Quantitative hydrophilic interaction chromatography-mass spectrometry analysis of N-acetylneuraminic acid and N-acetylmannosamine in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2015 Sep; 1000(?):105-11. doi: 10.1016/j.jchromb.2015.07.018. [PMID: 26218770]
  • Izabella Z A Pawluczyk, Maryam G Najafabadi, Jeremy R Brown, Alan Bevington, Peter S Topham. Sialic acid supplementation ameliorates puromycin aminonucleoside nephrosis in rats. Laboratory investigation; a journal of technical methods and pathology. 2015 Sep; 95(9):1019-28. doi: 10.1038/labinvest.2015.78. [PMID: 26121320]
  • Anas M Abdel Rahman, Michael Ryczko, Miyako Nakano, Judy Pawling, Tania Rodrigues, Anita Johswich, Naoyuki Taniguchi, James W Dennis. Golgi N-glycan branching N-acetylglucosaminyltransferases I, V and VI promote nutrient uptake and metabolism. Glycobiology. 2015 Feb; 25(2):225-40. doi: 10.1093/glycob/cwu105. [PMID: 25395405]
  • Mitsutaka Ogawa, Shogo Sawaguchi, Takami Kawai, Daita Nadano, Tsukasa Matsuda, Hirokazu Yagi, Koichi Kato, Koichi Furukawa, Tetsuya Okajima. Impaired O-linked N-acetylglucosaminylation in the endoplasmic reticulum by mutated epidermal growth factor (EGF) domain-specific O-linked N-acetylglucosamine transferase found in Adams-Oliver syndrome. The Journal of biological chemistry. 2015 Jan; 290(4):2137-49. doi: 10.1074/jbc.m114.598821. [PMID: 25488668]
  • Michael C E Niemann, Tomáš Werner. Endoplasmic reticulum: Where nucleotide sugar transport meets cytokinin control mechanisms. Plant signaling & behavior. 2015; 10(10):e1072668. doi: 10.1080/15592324.2015.1072668. [PMID: 26418963]
  • Jamie Imbriolo, Rudo F Mapanga, M Faadiel Essop. The hexosamine biosynthetic pathway induces gene promoter activity of acetyl-CoA carboxylase beta. Biochemical and biophysical research communications. 2014 Sep; 452(3):734-9. doi: 10.1016/j.bbrc.2014.08.142. [PMID: 25195817]
  • Thangavelu Muthukumar, Kannan Anbarasu, Dharmalingam Prakash, Thotapalli Parvathaleswara Sastry. Effect of growth factors and pro-inflammatory cytokines by the collagen biocomposite dressing material containing Macrotyloma uniflorum plant extract-In vivo wound healing. Colloids and surfaces. B, Biointerfaces. 2014 Sep; 121(?):178-88. doi: 10.1016/j.colsurfb.2014.06.018. [PMID: 24981560]
  • Wahiba Berrabah, Pierrette Aumercier, Céline Gheeraert, Hélène Dehondt, Emmanuel Bouchaert, Jérémy Alexandre, Maheul Ploton, Claire Mazuy, Sandrine Caron, Anne Tailleux, Jérôme Eeckhoute, Tony Lefebvre, Bart Staels, Philippe Lefebvre. Glucose sensing O-GlcNAcylation pathway regulates the nuclear bile acid receptor farnesoid X receptor (FXR). Hepatology (Baltimore, Md.). 2014 May; 59(5):2022-33. doi: 10.1002/hep.26710. [PMID: 24037988]
  • Vandana Panda, Tejas Thakur. Wound healing activity of the inflorescence of Typha elephantina (Cattail). The international journal of lower extremity wounds. 2014 Mar; 13(1):50-7. doi: 10.1177/1534734613516859. [PMID: 24351705]
  • Katherine A Patzel, Tal Yardeni, Erell Le Poëc-Celic, Petcharat Leoyklang, Heidi Dorward, Dominic S Alonzi, Nikolay V Kukushkin, Bixue Xu, Yongmin Zhang, Matthieu Sollogoub, Yves Blériot, William A Gahl, Marjan Huizing, Terry D Butters. Non-specific accumulation of glycosphingolipids in GNE myopathy. Journal of inherited metabolic disease. 2014 Mar; 37(2):297-308. doi: 10.1007/s10545-013-9655-6. [PMID: 24136589]
  • Inken Padberg, Erik Peter, Sandra González-Maldonado, Henning Witt, Matthias Mueller, Tanja Weis, Bianca Bethan, Volker Liebenberg, Jan Wiemer, Hugo A Katus, Dietrich Rein, Philipp Schatz. A new metabolomic signature in type-2 diabetes mellitus and its pathophysiology. PloS one. 2014; 9(1):e85082. doi: 10.1371/journal.pone.0085082. [PMID: 24465478]
  • Mohammad Reza Tabandeh, Ahamd Oryan, Adel Mohhammad-Alipour, Abotorab Tabatabaei-Naieni. Silibinin regulates matrix metalloproteinase 3 (stromelysine1) gene expression, hexoseamines and collagen production during rat skin wound healing. Phytotherapy research : PTR. 2013 Aug; 27(8):1149-53. doi: 10.1002/ptr.4839. [PMID: 22976003]
  • Shiguo Chen, Ka-Chai Siu, Wen-Qiang Wang, Xing-Xun Liu, Jian-Yong Wu. Structure and antioxidant activity of a novel poly-N-acetylhexosamine produced by a medicinal fungus. Carbohydrate polymers. 2013 Apr; 94(1):332-8. doi: 10.1016/j.carbpol.2012.12.067. [PMID: 23544546]
  • Brent A Penque, April M Hoggatt, B Paul Herring, Jeffrey S Elmendorf. Hexosamine biosynthesis impairs insulin action via a cholesterolgenic response. Molecular endocrinology (Baltimore, Md.). 2013 Mar; 27(3):536-47. doi: 10.1210/me.2012-1213. [PMID: 23315940]
  • Benjamin Lauzier, Fanny Vaillant, Clemence Merlen, Roselle Gélinas, Bertrand Bouchard, Marie-Eve Rivard, Francois Labarthe, Vern W Dolinsky, Jason R B Dyck, Bruce G Allen, John C Chatham, Christine Des Rosiers. Metabolic effects of glutamine on the heart: anaplerosis versus the hexosamine biosynthetic pathway. Journal of molecular and cellular cardiology. 2013 Feb; 55(?):92-100. doi: 10.1016/j.yjmcc.2012.11.008. [PMID: 23201305]
  • V Vinod Prabhu, C Guruvayoorappan. Inhibition of metastatic lung cancer in C57BL/6 mice by marine mangrove Rhizophora apiculata. Asian Pacific journal of cancer prevention : APJCP. 2013; 14(3):1833-40. doi: 10.7314/apjcp.2013.14.3.1833. [PMID: 23679283]
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