Leptosidin (BioDeep_00000006899)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


2- [ (Z) - (3,4-Dihydroxyphenyl) methylene ] -6-hydroxy-7-methoxybenzofuran-3 (2H) -one

化学式: C16H12O6 (300.0634)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C12C(=O)C(=CC3C=C(O)C(O)=CC=3)OC=1C(OC)=C(O)C=C2
InChI: InChI=1S/C16H12O6/c1-21-16-11(18)5-3-9-14(20)13(22-15(9)16)7-8-2-4-10(17)12(19)6-8/h2-7,17-19H,1H3

描述信息

A hydroxyaurone that is aurone substituted by hydroxy groups at positions 6, 3 and 4 and a methoxy group at position 7.

同义名列表

4 个代谢物同义名

Leptosidin; 2- [ (Z) - (3,4-Dihydroxyphenyl) methylene ] -6-hydroxy-7-methoxybenzofuran-3 (2H) -one; SCHEMBL6616173; Leptosidin



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

20 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 LDHA, NOS2, PKM, PPARG, PRKAA2, PTGS2, SIRT1
Peripheral membrane protein 2 HK2, PTGS2
Endoplasmic reticulum membrane 2 HMOX1, PTGS2
Nucleus 8 HMOX1, LDHA, NOS2, PARP1, PKM, PPARG, PRKAA2, SIRT1
cytosol 11 HK2, HMOX1, LDHA, LEP, NOS2, PARP1, PKM, PPARG, PRKAA2, SIRT1, SLC2A1
dendrite 1 PRKAA2
nuclear body 1 PARP1
centrosome 1 HK2
nucleoplasm 6 HMOX1, NOS2, PARP1, PPARG, PRKAA2, SIRT1
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 2 DPP4, SLC2A1
Cytoplasmic side 1 HMOX1
lamellipodium 1 DPP4
Multi-pass membrane protein 1 SLC2A1
cell junction 1 DPP4
cell surface 1 DPP4
Golgi apparatus 1 PRKAA2
Golgi membrane 2 INS, SLC2A1
lysosomal membrane 1 DPP4
neuronal cell body 1 PRKAA2
sarcolemma 1 SLC2A1
Cytoplasm, cytosol 3 HK2, NOS2, PARP1
Presynapse 1 SLC2A1
plasma membrane 3 DPP4, NOS2, SLC2A1
Membrane 7 DPP4, HK2, HMOX1, LDHA, PARP1, PRKAA2, SLC2A1
apical plasma membrane 2 DPP4, SLC2A1
axon 1 PRKAA2
basolateral plasma membrane 1 SLC2A1
caveola 2 PTGS2, SLC2A1
extracellular exosome 4 DPP4, LDHA, PKM, SLC2A1
endoplasmic reticulum 2 HMOX1, PTGS2
extracellular space 3 HMOX1, INS, LEP
perinuclear region of cytoplasm 3 HMOX1, NOS2, PPARG
intercalated disc 1 SLC2A1
intercellular canaliculus 1 DPP4
mitochondrion 5 HK2, LDHA, PARP1, PKM, SIRT1
protein-containing complex 2 PARP1, PTGS2
intracellular membrane-bounded organelle 2 HK2, PPARG
Microsome membrane 1 PTGS2
chromatin silencing complex 1 SIRT1
Secreted 4 DPP4, HK2, INS, LEP
extracellular region 5 DNAH9, DPP4, INS, LEP, PKM
Mitochondrion outer membrane 1 HK2
Single-pass membrane protein 1 DPP4
mitochondrial outer membrane 2 HK2, HMOX1
anchoring junction 1 DPP4
transcription regulator complex 1 PARP1
motile cilium 1 DNAH9
photoreceptor inner segment 1 SLC2A1
Extracellular vesicle 1 PKM
Z disc 1 SLC2A1
nucleolus 2 PARP1, SIRT1
midbody 1 SLC2A1
Cytoplasm, P-body 1 NOS2
P-body 1 NOS2
Single-pass type II membrane protein 1 DPP4
vesicle 1 PKM
Apical cell membrane 1 DPP4
Cytoplasm, perinuclear region 1 NOS2
heterochromatin 1 SIRT1
Membrane raft 1 DPP4
focal adhesion 1 DPP4
microtubule 1 DNAH9
Peroxisome 1 NOS2
sarcoplasmic reticulum 1 HK2
peroxisomal matrix 1 NOS2
Nucleus, PML body 1 SIRT1
PML body 1 SIRT1
collagen-containing extracellular matrix 1 PKM
axoneme 1 DNAH9
nuclear speck 1 PRKAA2
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 2 PTGS2, SIRT1
nuclear outer membrane 1 PTGS2
receptor complex 1 PPARG
neuron projection 1 PTGS2
cilium 1 PKM
chromatin 3 PARP1, PPARG, SIRT1
Chromosome 1 PARP1
Nucleus, nucleolus 1 PARP1
nuclear replication fork 1 PARP1
chromosome, telomeric region 1 PARP1
blood microparticle 1 SLC2A1
Cytoplasm, cytoskeleton, cilium axoneme 1 DNAH9
site of double-strand break 1 PARP1
fibrillar center 1 SIRT1
nuclear envelope 2 PARP1, SIRT1
Endomembrane system 1 DPP4
endosome lumen 1 INS
female germ cell nucleus 1 SLC2A1
Melanosome 1 SLC2A1
cytoplasmic stress granule 1 PRKAA2
euchromatin 1 SIRT1
ficolin-1-rich granule lumen 1 PKM
secretory granule lumen 2 INS, PKM
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 INS, PTGS2
cortical actin cytoskeleton 1 SLC2A1
endocytic vesicle 1 DPP4
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
9+2 motile cilium 1 DNAH9
dynein complex 1 DNAH9
Single-pass type IV membrane protein 1 HMOX1
protein-DNA complex 1 PARP1
female pronucleus 1 SLC2A1
eNoSc complex 1 SIRT1
rDNA heterochromatin 1 SIRT1
Rough endoplasmic reticulum 1 PKM
nucleotide-activated protein kinase complex 1 PRKAA2
site of DNA damage 1 PARP1
lamellipodium membrane 1 DPP4
oxidoreductase complex 1 LDHA
cortical cytoskeleton 1 NOS2
Cell projection, lamellipodium membrane 1 DPP4
Cell projection, invadopodium membrane 1 DPP4
[Poly [ADP-ribose] polymerase 1, processed N-terminus]: Chromosome 1 PARP1
[Poly [ADP-ribose] polymerase 1, processed C-terminus]: Cytoplasm 1 PARP1
glucose transporter complex 1 SLC2A1
[Isoform M2]: Cytoplasm 1 PKM
[Isoform M1]: Cytoplasm 1 PKM
[Dipeptidyl peptidase 4 soluble form]: Secreted 1 DPP4
outer dynein arm 1 DNAH9
[SirtT1 75 kDa fragment]: Cytoplasm 1 SIRT1
distal portion of axoneme 1 DNAH9


文献列表

  • Antoni Pardede, Koharu Mashita, Masayuki Ninomiya, Kaori Tanaka, Mamoru Koketsu. Flavonoid profile and antileukemic activity of Coreopsis lanceolata flowers. Bioorganic & medicinal chemistry letters. 2016 06; 26(12):2784-2787. doi: 10.1016/j.bmcl.2016.04.069. [PMID: 27155901]
  • Yoshiharu Okada, Mari Okita, Yoshihiro Murai, Yuka Okano, Masato Nomura. Isolation and identification of flavonoids from Coreopsis lanceolata L. petals. Natural product research. 2014; 28(3):201-4. doi: 10.1080/14786419.2013.856905. [PMID: 24236492]