Taraxasterol (BioDeep_00000006891)

 

Secondary id: BioDeep_00000230191

human metabolite PANOMIX_OTCML-2023 Endogenous natural product


代谢物信息卡片


(3S,4aR,6aR,6aR,6bR,8aR,12S,12aS,14aR,14bR)-4,4,6a,6b,8a,12,14b-heptamethyl-11-methylidene-1,2,3,4a,5,6,6a,7,8,9,10,12,12a,13,14,14a-hexadecahydropicen-3-ol

化学式: C30H50O (426.3861)
中文名称: 蒲公英甾醇
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 31.58%

分子结构信息

SMILES: C=C1CCC2(C)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1C
InChI: InChI=1S/C30H50O/c1-19-11-14-27(5)17-18-29(7)21(25(27)20(19)2)9-10-23-28(6)15-13-24(31)26(3,4)22(28)12-16-30(23,29)8/h20-25,31H,1,9-18H2,2-8H3

描述信息

Constituent of dandelion roots (Taraxacum officinale), Roman chamomile flowers (Anthemis nobilis) and many other plants. Taraxasterol is found in many foods, some of which are soy bean, chicory, evening primrose, and common grape.
Taraxasterol is found in alcoholic beverages. Taraxasterol is a constituent of dandelion roots (Taraxacum officinale), Roman chamomile flowers (Anthemis nobilis) and many other plants
Taraxasterol is a pentacyclic triterpenoid isolated from Taraxacum mongolicum. Taraxasterol has a role as a metabolite and an anti-inflammatory agent[1].
Taraxasterol is a pentacyclic triterpenoid isolated from Taraxacum mongolicum. Taraxasterol has a role as a metabolite and an anti-inflammatory agent[1].

同义名列表

13 个代谢物同义名

(3S,4aR,6aR,6aR,6bR,8aR,12S,12aS,14aR,14bR)-4,4,6a,6b,8a,12,14b-heptamethyl-11-methylidene-1,2,3,4a,5,6,6a,7,8,9,10,12,12a,13,14,14a-hexadecahydropicen-3-ol; 4,4,6a,6b,8a,12,14b-Heptamethyl-11-methylidene-1,2,3,4a,5,6,6a,7,8,9,10,12,12a,13,14,14a-hexadecahydropicen-3-ol; 4,4,6a,6b,8a,12,14b-heptamethyl-11-methylidene-hexadecahydropicen-3-ol; 4,4,6a,6b,8a,12,14b-heptamethyl-11-methylidene-docosahydropicen-3-ol; 18alpha,19alpha-urs-20(30)-en-3beta-ol; a-Anthesterin; Taraxasterol; taraxasterin; a-Lactucerol; Inusterol a; Pyrethrol; Saussurol; Taraxasterol



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

658 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Chuanlei Li, Zhihuang Zheng, Yun Xie, Nan Zhu, Jinfang Bao, Qing Yu, Zhigang Zhou, Jun Liu. Protective effect of taraxasterol on ischemia/reperfusion-induced acute kidney injury via inhibition of oxidative stress, inflammation, and apoptosis. International immunopharmacology. 2020 Dec; 89(Pt A):107169. doi: 10.1016/j.intimp.2020.107169. [PMID: 33183976]
  • Mahboubeh Yousefi Ghale-Salimi, Maryam Eidi, Nasser Ghaemi, Ramezan Ali Khavari-Nejad. Inhibitory effects of taraxasterol and aqueous extract of Taraxacum officinale on calcium oxalate crystallization: in vitro study. Renal failure. 2018 Nov; 40(1):298-305. doi: 10.1080/0886022x.2018.1455595. [PMID: 29619876]
  • Mahboubeh Yousefi Ghale-Salimi, Maryam Eidi, Nasser Ghaemi, Ramezan Ali Khavari-Nejad. Antiurolithiatic effect of the taraxasterol on ethylene glycol induced kidney calculi in male rats. Urolithiasis. 2018 Oct; 46(5):419-428. doi: 10.1007/s00240-017-1023-9. [PMID: 29189886]
  • Tianhao Bao, Yang Ke, Yifan Wang, Weiwei Wang, Yuehua Li, Yan Wang, Xiang Kui, Qixin Zhou, Han Zhou, Cheng Zhang, Dongming Zhou, Lin Wang, Chunjie Xiao. Taraxasterol suppresses the growth of human liver cancer by upregulating Hint1 expression. Journal of molecular medicine (Berlin, Germany). 2018 07; 96(7):661-672. doi: 10.1007/s00109-018-1652-7. [PMID: 29806073]
  • Shasha Wang, Ying Wang, Xinyu Liu, Lizeng Guan, Longzheng Yu, Xuemei Zhang. Anti-inflammatory and anti-arthritic effects of taraxasterol on adjuvant-induced arthritis in rats. Journal of ethnopharmacology. 2016 Jul; 187(?):42-8. doi: 10.1016/j.jep.2016.04.031. [PMID: 27109342]
  • Nan Zhang, Li Pang, Ning Dong, Dahai Xu, Hong Xu. Quantification of taraxasterol in rat plasma by LC/MS/MS: application to a pharmacokinetic study. Biomedical chromatography : BMC. 2015 Nov; 29(11):1643-9. doi: 10.1002/bmc.3473. [PMID: 25873241]