Gentamicin (BioDeep_00000006570)

   

human metabolite blood metabolite Chemicals and Drugs


代谢物信息卡片


2-{[4,6-diamino-3-({3-amino-6-[1-(methylamino)ethyl]oxan-2-yl}oxy)-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol

化学式: C21H43N5O7 (477.3162328)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 3.45%

分子结构信息

SMILES: CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)NC
InChI: InChI=1S/C21H43N5O7/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20/h9-20,25-29H,5-8,22-24H2,1-4H3

描述信息

A complex of three different closely related aminoglycoside sulfates, Gentamicins C1, C2, and C1(subA), obtained from Micromonospora purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit protein synthesis (genetic translation). [PubChem]
D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06A - Antibiotics for topical use
S - Sensory organs > S03 - Ophthalmological and otological preparations > S03A - Antiinfectives > S03AA - Antiinfectives
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01G - Aminoglycoside antibacterials
S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AA - Antibiotics
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D005839 - Gentamicins
S - Sensory organs > S02 - Otologicals > S02A - Antiinfectives > S02AA - Antiinfectives
C784 - Protein Synthesis Inhibitor > C2363 - Aminoglycoside Antibiotic
D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors
C254 - Anti-Infective Agent > C258 - Antibiotic

同义名列表

15 个代谢物同义名

2-{[4,6-diamino-3-({3-amino-6-[1-(methylamino)ethyl]oxan-2-yl}oxy)-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol; Sulfate, gentamicin; Gentamicin sulfate; Gentamicin C1; Gentamycins; Gentamicins; Gentamycin; Gentacycol; gentamicin; g Myticin; Garamycin; g-Myticin; Genticin; Gentavet; GMyticin



数据库引用编号

21 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

5 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yixin Rui, Xiumeng Zhang, Xinran Min, Hongxiao Xie, Xiuying Ma, Funeng Geng, Rong Liu. Unlocking renal Restoration: Mesaconine from Aconitum plants restore mitochondrial function to halt cell apoptosis in acute kidney injury. International immunopharmacology. 2024 May; 133(?):112170. doi: 10.1016/j.intimp.2024.112170. [PMID: 38691919]
  • Yanwen Zhuang, Yu Ouyang, Li Ding, Miaowen Xu, Fanfeng Shi, Dan Shan, Dawei Cao, Xiaowei Cao. Source Tracing of Kidney Injury via the Multispectral Fingerprint Identified by Machine Learning-Driven Surface-Enhanced Raman Spectroscopic Analysis. ACS sensors. 2024 May; 9(5):2622-2633. doi: 10.1021/acssensors.4c00407. [PMID: 38700898]
  • Marina M Stanković, Petar M Ristivojević, Đurđa D Ivković, Milena G Milutinović, Jelena N Terzić, Olgica D Stefanović. A comprehensive study on Geranium robertianum L. antibacterial potential. Journal of applied microbiology. 2024 May; 135(5):. doi: 10.1093/jambio/lxae106. [PMID: 38658191]
  • Hai Bang Pan, Yan Cui, Zhi Hang Wu, Ying Meng, Tian Ming Wang, Qi Fu, Qian Chen, Quan Xin Chen, Bo Wang. Effect of Different Local Antibiotic Regimens on Prevention of Postoperative Infection in Clean Surgical Wounds: A Systematic Review and Network Meta-analysis. Advances in skin & wound care. 2024 Apr; 37(4):216-223. doi: 10.1097/asw.0000000000000094. [PMID: 38353666]
  • Özge Kendirlinan, Yurdun Kuyucu, Bilge Güzelel, Ebru Dündar Yenilmez, Abdullah Tuli, Gülşah Seydaoğlu, Ufuk Özgü Mete. Investigation the effects of 2-aminoethoxydiphenyl borate (2-APB) on aminoglycoside nephrotoxicity. Ultrastructural pathology. 2024 Jan; 48(1):29-41. doi: 10.1080/01913123.2023.2278629. [PMID: 37970647]
  • Asmaa I Matouk, Eman M Awad, Amr A K Mousa, Sara M N Abdelhafez, Usama A Fahmy, Mohamed A El-Moselhy, Ashraf B Abdel-Naim, Aliaa Anter. Dihydromyricetin protects against gentamicin-induced nephrotoxicity via upregulation of renal SIRT3 and PAX2. Life sciences. 2024 Jan; 336(?):122318. doi: 10.1016/j.lfs.2023.122318. [PMID: 38035992]
  • Seyda Nur Coban, Ilker Polatoglu, Erdal Eroglu. Methyl cellulose/okra mucilage composite films, functionalized with Hypericum perforatum oil and gentamicin, as a potential wound dressing. International journal of biological macromolecules. 2024 Jan; 254(Pt 1):127757. doi: 10.1016/j.ijbiomac.2023.127757. [PMID: 38287573]
  • Metin Yıldırım, Mehmet Erşatır, Ulas Değirmenci, Akın Yigin, Mustafa Boyraz Unal, Muhammet Emin Guldur, Onur Demirkol, Elife Sultan Giray. Potential Protective Effects of Ruta Chalepensis L. Extracts Against Gentamicin-Induced Nephrotoxicity via Reduction on Apoptotic, DNA Damage and Oxidative Stress Markers in Mice. International journal of environmental health research. 2023 Dec; 33(12):1533-1545. doi: 10.1080/09603123.2022.2105824. [PMID: 35917490]
  • H A Al-Amer, N S Al-Sowayan, H A Alfheeaid, S A Althwab, S A Alrobaish, E M Hamad, K H Musa, H M Mousa. Oral administration of naringenin and a mixture of coconut water and Arabic gum attenuate oxidative stress and lipid peroxidation in gentamicin-induced nephrotoxicity in rats. European review for medical and pharmacological sciences. 2023 Nov; 27(21):10427-10437. doi: 10.26355/eurrev_202311_34317. [PMID: 37975366]
  • Mara Aurori, Sanda Andrei, Alexandra Iulia Dreanca, Andreea Georgiana Morohoschi, Mihaela Cotul, Mihaela Niculae, Monica Irina Nan, Andrei Răzvan Codea, Adrian Florin Gal. The Nephroprotective Effect of Cornelian Cherry (Cornus mas L.) and Rowanberry (Sorbus aucuparia L.) in Gentamicin-Induced Nephrotoxicity on Wistar Rats with Emphasis on the Evaluation of Novel Renal Biomarkers and the Antioxidant Capacity in Correlation with Nitro-Oxidative Stress. Nutrients. 2023 Oct; 15(20):. doi: 10.3390/nu15204392. [PMID: 37892466]
  • Aleksandra Gostyńska, Katarzyna Dettlaff, Anna Jelińska, Maciej Stawny. Improving the Safety of Clinical Management of COVID-19 Patients Receiving Aminoglycosides and Parenteral Nutrition: Y-site Compatibility Studies. Journal of pharmaceutical sciences. 2023 10; 112(10):2597-2603. doi: 10.1016/j.xphs.2023.08.007. [PMID: 37595749]
  • Saumya Singh, Taru Verma, Balaram Khamari, Eswarappa Pradeep Bulagonda, Dipankar Nandi, Siva Umapathy. Antimicrobial Resistance Studies Using Raman Spectroscopy on Clinically Relevant Bacterial Strains. Analytical chemistry. 2023 08; 95(30):11342-11351. doi: 10.1021/acs.analchem.3c01453. [PMID: 37463121]
  • Morteza Saeedavi, Mehdi Goudarzi, Iman Fatemi, Zahra Basir, Seyyed Mohammad Ali Noori, Saeed Mehrzadi. Gentisic acid mitigates gentamicin-induced nephrotoxicity in rats. Tissue & cell. 2023 Aug; 84(?):102191. doi: 10.1016/j.tice.2023.102191. [PMID: 37556917]
  • Xue Wang, Liming Fu, Shaoning Guo, Xuedong Fang. A meta-analysis examined the effect of topical nursing application of antimicrobial as a prophylaxis for the stoppage of surgical wound infection in colorectal surgery. International wound journal. 2023 Aug; 20(6):2010-2019. doi: 10.1111/iwj.14064. [PMID: 36727574]
  • Michalina Adaszyńska-Skwirzyńska, Sławomir Zych, Mateusz Bucław, Danuta Majewska, Małgorzata Dzięcioł, Danuta Szczerbińska. Evaluation of the Antibacterial Activity of Gentamicin in Combination with Essential Oils Isolated from Different Cultivars and Morphological Parts of Lavender (Lavandula angustifolia Mill.) against Selected Bacterial Strains. Molecules (Basel, Switzerland). 2023 Jul; 28(15):. doi: 10.3390/molecules28155781. [PMID: 37570751]
  • Arefeh Ebadati, Mojgan Oshaghi, Sara Saeedi, Parastoo Parsa, Vahid Pirhajati Mahabadi, Morteza Karimi, Atefeh Jahandideh Hajiebrahimdehi, Michael R Hamblin, Mahdi Karimi. Mechanism and antibacterial synergies of poly(Dabco-BBAC) nanoparticles against multi-drug resistant Pseudomonas aeruginosa isolates from human burns. Bioorganic chemistry. 2023 Jul; 140(?):106718. doi: 10.1016/j.bioorg.2023.106718. [PMID: 37566942]
  • A M Al-Johani, N S Al-Sowayan. Protective effect of ethanolic extract of Elettaria Cardamomum against gentamicin hepato-renal toxicity in male albino rats. European review for medical and pharmacological sciences. 2023 Jun; 27(11):4828-4841. doi: 10.26355/eurrev_202306_32599. [PMID: 37318456]
  • Yuanwang Liu, Minmin Feng, Anders Johansen, Dengmiao Cheng, Jianming Xue, Yao Feng, Shuanghu Fan, Zhaojun Li. Composting reduces the risks of antibiotic resistance genes in maize seeds posed by gentamicin fermentation waste. The Science of the total environment. 2023 Apr; 870(?):161785. doi: 10.1016/j.scitotenv.2023.161785. [PMID: 36736399]
  • Abeer I M El-Sayed, Mostafa M El-Sheekh, Mofida E M Makhlof. Synergistic antibacterial effects of Ulva lactuca methanolic extract alone and in combination with different antibiotics on multidrug-resistant Klebsiella pneumoniae isolate. BMC microbiology. 2023 04; 23(1):106. doi: 10.1186/s12866-023-02854-5. [PMID: 37072731]
  • Xiran Li, Xavier F Hospital, Eva Hierro, Manuela Fernández, Lina Sheng, Luxin Wang. Formation of Listeria monocytogenes persister cells in the produce-processing environment. International journal of food microbiology. 2023 Apr; 390(?):110106. doi: 10.1016/j.ijfoodmicro.2023.110106. [PMID: 36753793]
  • Fatima Saleem, Naila Safdar, Iram Fatima, Azra Yasmin, Wajid Hussain. Functionalization of ampicillin and gentamicin with biogenic copper nanoparticles (CuNPs) remodel antimicrobial and cytotoxic outcome against MDR clinical isolates. Archives of microbiology. 2023 Feb; 205(3):88. doi: 10.1007/s00203-023-03425-y. [PMID: 36781492]
  • Arab Gul, Haroon Khan, Sayyed Ibrahim Shah, Khalaf F Alsharif, Safa H Qahl, Inayat Ur Rehman, Khang Wen Goh, Chrismawan Ardianto, Long Chiau Ming. Pharmaceutical Development of Intraperitoneal Arachis hypogaea as a Renal Protective Agent. Frontiers in bioscience (Landmark edition). 2023 01; 28(1):14. doi: 10.31083/j.fbl2801014. [PMID: 36722262]
  • Zhang Ruijuan, Xiao Li, Wang Yingjie, Wang Rui, Lu Chunqing. Effects of Catheter Tracking Management on Urinary Tract Function and Infection Rates in Patients With Spinal Cord Injury. Alternative therapies in health and medicine. 2023 Jan; ?(?):. doi: . [PMID: 36634314]
  • M R A Ferreira, L B Lima, E C F Santos, J C B Machado, W A V Silva, P M G Paiva, T H Napoleão, L A L Soares. Eugenia uniflora: a promising natural alternative against multidrug-resistant bacteria. Brazilian journal of biology = Revista brasleira de biologia. 2023; 83(?):e274084. doi: 10.1590/1519-6984.274084. [PMID: 37585932]
  • Shah Rucksana Akhter Urme, Syeda Fahmida Ahmed, Mohammed Mostafa Al Quadir, Mst Rubaiat Nazneen Akhand, Mohammad Mehedi Hasan Khan. Evaluation of the Antimicrobial Activity of Phytochemicals from Tea and Agarwood Leaf Extracts against Isolated Bacteria from Poultry and Curd. TheScientificWorldJournal. 2023; 2023(?):6674891. doi: 10.1155/2023/6674891. [PMID: 38021480]
  • Damir Suljević, Maja Mitrašinović-Brulić, Muhamed Fočak. L-cysteine protective effects against platelet disaggregation and echinocyte occurrence in gentamicin-induced kidney injury. Molecular and cellular biochemistry. 2023 Jan; 478(1):13-22. doi: 10.1007/s11010-022-04498-x. [PMID: 35708867]
  • Seyed Sajad Hossieni Geshnigani, Masoud Mahdavinia, Mojtaba Kalantar, Mehdi Goudarzi, Layasadat Khorsandi, Hadi Kalantar. Diosmin prophylaxis reduces gentamicin-induced kidney damage in rats. Naunyn-Schmiedeberg's archives of pharmacology. 2023 01; 396(1):63-71. doi: 10.1007/s00210-022-02295-3. [PMID: 36121447]
  • Bilge Tuna, Gökhan Tüzemen. Protective effects of nigella sativa oil against gentamicin-induced ototoxicity in rats: A dose-ranging study. International journal of pediatric otorhinolaryngology. 2023 Jan; 164(?):111405. doi: 10.1016/j.ijporl.2022.111405. [PMID: 36481814]
  • Abdollah Arjmand, Saba Shiranirad, Fateme Ameritorzani, Farzaneh Kamranfar, Enayatollah Seydi, Jalal Pourahmad. Mitochondrial transplantation against gentamicin-induced toxicity on rat renal proximal tubular cells: the higher activity of female rat mitochondria. In vitro cellular & developmental biology. Animal. 2023 Jan; 59(1):31-40. doi: 10.1007/s11626-022-00743-1. [PMID: 36630058]
  • Dhama Al-Sallami, Amjed Alsultan, Kadhim Hassan Abbas, Simon R Clarke. Evaluation of efflux pump inhibitory activity of some plant extracts and using them as adjuvants to potentiate the inhibitory activity of some antibiotics against Staphylococcus aureus. Open veterinary journal. 2023 01; 13(1):42-47. doi: 10.5455/ovj.2023.v13.i1.5. [PMID: 36777436]
  • Billy Tchegnitegni Toussie, Ruland Tchuinkeu Nguengang, Isabelle Kamga Mawabo, Rémy Bertrand Teponno, Jean Jules Kezetas Bankeu, Jean Rodolphe Chouna, Celine Ngeufeu Nkenfou, Léon Azefack Tapondjou, Norbert Sewald, Bruno Ndjakou Lenta. Bioactive Arylnaphthalide Lignans from Justicia depauperata. Journal of natural products. 2022 12; 85(12):2731-2739. doi: 10.1021/acs.jnatprod.2c00624. [PMID: 36469853]
  • Lin Yue, Ya-Ru Yang, Wen-Xian Ma, Hong-Yan Wang, Qian-Wen Fan, Yue-Yue Wang, Chao Li, Jing Wang, Zi-Mu Hu, Xue-Fu Wang, Feng-He Li, Ming-Ming Liu, Juan Jin, Chao Shi, Jia-Gen Wen. Epigallocatechin Gallate Attenuates Gentamicin-Induced Nephrotoxicity by Suppressing Apoptosis and Ferroptosis. Molecules (Basel, Switzerland). 2022 Dec; 27(23):. doi: 10.3390/molecules27238564. [PMID: 36500657]
  • Yasmina M Abd-Elhakim, Sabry M Abdel-Motal, Seham M Malhat, Hend I Mostafa, Walied M Ibrahim, Rasha R Beheiry, Attia A A Moselhy, Enas N Said. Curcumin attenuates gentamicin and sodium salicylate ototoxic effects by modulating the nuclear factor-kappaB and apoptotic pathways in rats. Environmental science and pollution research international. 2022 Dec; 29(60):89954-89968. doi: 10.1007/s11356-022-21932-1. [PMID: 35859240]
  • Pongrapee Laorodphun, Rada Cherngwelling, Aussara Panya, Phatchawan Arjinajarn. Curcumin protects rats against gentamicin-induced nephrotoxicity by amelioration of oxidative stress, endoplasmic reticulum stress and apoptosis. Pharmaceutical biology. 2022 Dec; 60(1):491-500. doi: 10.1080/13880209.2022.2037663. [PMID: 35188833]
  • Konstantinos Ioannidis, Aaron Cohen, Mohammad Ghosheh, Avner Ehrlich, Amit Fischer, Merav Cohen, Yaakov Nahmias. Aminoglycoside-induced lipotoxicity and its reversal in kidney on chip. Lab on a chip. 2022 11; 22(23):4469-4480. doi: 10.1039/d2lc00825d. [PMID: 36281785]
  • Ting Xu, Ke-Liang Wu, Ke Jie. Comprehensive meta-analysis of antibiotic-impregnated bone cement versus plain bone cement in primary total knee arthroplasty for preventing periprosthetic joint infection. Chinese journal of traumatology = Zhonghua chuang shang za zhi. 2022 Nov; 25(6):325-330. doi: 10.1016/j.cjtee.2022.06.001. [PMID: 35717367]
  • Murugan Thulasi Meenu, Grace Kaul, Abdul Akhir, Manjulika Shukla, Kokkuvayil Vasu Radhakrishnan, Sidharth Chopra. Developing the Natural Prenylflavone Artocarpin from Artocarpus hirsutus as a Potential Lead Targeting Pathogenic, Multidrug-Resistant Staphylococcus aureus, Persisters and Biofilms with No Detectable Resistance. Journal of natural products. 2022 10; 85(10):2413-2423. doi: 10.1021/acs.jnatprod.2c00621. [PMID: 36222797]
  • Xiu-Jun Xu, Mei-Ling Zhang, Yan-Min Hou, Ke Zhang, Da-Hong Yao, Guo-Yu Li, Wei-Bing Kou, Hang-Yu Wang, Jin-Hui Wang. The Amomum tsao-ko Essential Oils Inhibited Inflammation and Apoptosis through p38/JNK MAPK Signaling Pathway and Alleviated Gentamicin-Induced Acute Kidney Injury. Molecules (Basel, Switzerland). 2022 Oct; 27(20):. doi: 10.3390/molecules27207121. [PMID: 36296715]
  • Yasmine F Ibrahim, Somaia Hassan Hammady, Rehab A Rifaai, Shaimaa Waz, Mohamed Abdellah Ibrahim, Heba M Hafez. Dose-dependent ameliorating effect of lipoxin A4 on gentamicin-induced nephrotoxicity in rats: The role of TNFα, TGF-β, ICAM-1, and JNK signaling. Chemico-biological interactions. 2022 Oct; 366(?):110139. doi: 10.1016/j.cbi.2022.110139. [PMID: 36057361]
  • Hina Ali, Mengtian Pei, Hongchen Li, Wenqin Fang, Hongkun Mao, Hamid Ali Khan, Tariq Nadeem, Guodong Lu, Stefan Olsson. The Wheat Head Blight Pathogen Fusarium graminearum Can Recruit Collaborating Bacteria from Soil. Cells. 2022 09; 11(19):. doi: 10.3390/cells11193004. [PMID: 36230966]
  • Songyao Kang, Tingting Chen, Zhihui Hao, Xiao Yang, Mingfa Wang, Zhifang Zhang, Sijia Hao, Fengting Lang, Hongxia Hao. Oxymatrine Alleviates Gentamicin-Induced Renal Injury in Rats. Molecules (Basel, Switzerland). 2022 Sep; 27(19):. doi: 10.3390/molecules27196209. [PMID: 36234739]
  • Jan Felix, Ladislav Bumba, Clarissa Liesche, Angélique Fraudeau, Fabrice Rébeillé, Jessica Y El Khoury, Karine Huard, Benoit Gallet, Christine Moriscot, Jean-Philippe Kleman, Yoan Duhoo, Matthew Jessop, Eaazhisai Kandiah, Frédéric Barras, Juliette Jouhet, Irina Gutsche. The AAA+ ATPase RavA and its binding partner ViaA modulate E. coli aminoglycoside sensitivity through interaction with the inner membrane. Nature communications. 2022 09; 13(1):5502. doi: 10.1038/s41467-022-32992-9. [PMID: 36127320]
  • Yimeng Pang, Sijun Zhao, Zhiwei Liu, Jiayi Chen, Zehao Yang, Zixian He, Xing Shen, Hongtao Lei, Xiangmei Li. An enhanced immunochromatography assay based on colloidal gold-decorated polydopamine for rapid and sensitive determination of gentamicin in animal-derived food. Food chemistry. 2022 Sep; 387(?):132916. doi: 10.1016/j.foodchem.2022.132916. [PMID: 35417844]
  • Manal M Hussein, Hussam A Althagafi, Fahad Alharthi, Ashraf Albrakati, Khalaf F Alsharif, Abdulrahman Theyab, Rami B Kassab, Ahmad H Mufti, Mohammad Algahtani, Atif Abdulwahab A Oyouni, Roua S Baty, Ahmed E Abdel Moneim, Maha S Lokman. Apigenin attenuates molecular, biochemical, and histopathological changes associated with renal impairments induced by gentamicin exposure in rats. Environmental science and pollution research international. 2022 Sep; 29(43):65276-65288. doi: 10.1007/s11356-022-20235-9. [PMID: 35484458]
  • Khalid Saad Alharbi, Tabinda Ali, Yogendra Singh, Ahmed Saleh Ali Al-Ghamdi, Imran Kazmi, Fahad A Al-Abbasi, Sami I Alzarea, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Sachin Kumar Singh, Dinesh Kumar Chellappan, Kamal Dua, Gaurav Gupta. Biochemical interaction of pyrvinium in gentamicin-induced acute kidney injury by modulating calcium dyshomeostasis and mitochondrial dysfunction. Chemico-biological interactions. 2022 Aug; 363(?):110020. doi: 10.1016/j.cbi.2022.110020. [PMID: 35750223]
  • Yousong Li, Qin Ding, Jinsheng Gao, Chunxia Li, Pengxiao Hou, Jie Xu, Kaiqi Cao, Min Hu, Lin Cheng, Xixing Wang, Xiaoling Yang. Novel mechanisms underlying inhibition of inflammation-induced angiogenesis by dexamethasone and gentamicin via PI3K/AKT/NF-κB/VEGF pathways in acute radiation proctitis. Scientific reports. 2022 08; 12(1):14116. doi: 10.1038/s41598-022-17981-8. [PMID: 35982137]
  • Ajay Guru, Gokul Sudhakaran, Manikandan Velayutham, Raghul Murugan, Raman Pachaiappan, Ramzi A Mothana, Omar M Noman, Annie Juliet, Jesu Arockiaraj. Daidzein normalized gentamicin-induced nephrotoxicity and associated pro-inflammatory cytokines in MDCK and zebrafish: Possible mechanism of nephroprotection. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2022 Aug; 258(?):109364. doi: 10.1016/j.cbpc.2022.109364. [PMID: 35523404]
  • Heba S Zaky, Somaia A Abdel-Sattar, Albatoul Allam, Hebatalla I Ahmed. Further insights into the impact of rebamipide on gentamicin-induced nephrotoxicity in rats: modulation of SIRT1 and β-catenin/cyclin D1 pathways. Drug and chemical toxicology. 2022 Jul; ?(?):1-13. doi: 10.1080/01480545.2022.2104867. [PMID: 35899710]
  • Hiie Soeorg, Helgi Padari, Karin Kipper, Mari-Liis Ilmoja, Irja Lutsar, Tuuli Metsvaht. Pharmacokinetics of Gentamicin Components C1, C1a, and C2/C2a/C2b and Subsequent Decline in Glomerular Filtration Rate in Neonates. The AAPS journal. 2022 06; 24(4):77. doi: 10.1208/s12248-022-00727-9. [PMID: 35760955]
  • Shiori Yamamoto, Wataru Kitagawa, Motoki Nakano, Hiroshi Asakura, Tatsuya Nakayama, Eriko Iwabuchi, Teruo Sone, Kozo Asano. Prevalence and Characterization of Gentamicin Resistance Genes in Escherichia coli Isolates from Beef Cattle Feces in Japan. Current microbiology. 2022 Jun; 79(8):217. doi: 10.1007/s00284-022-02913-6. [PMID: 35704076]
  • Ahmed M Abd-Eldayem, Marwa A Dahpy, Dalia M Badary, Sulaiman Mohammed Alnasser, Mohammad Salem Hareedy. Celecoxib has Preventive and Therapeutic Benefits against Nephrotoxicity Caused by Gentamicin in Mice. Drug research. 2022 Jun; 72(5):259-267. doi: 10.1055/a-1785-4005. [PMID: 35359021]
  • Viviane Chaiben, Carolina Hikari Yamada, João Paulo Telles, Ana Paula de Andrade, Lavinia Nery Villa Stangler Arend, Victoria Stadler Tasca Ribeiro, Leticia Ramos Dantas, Paula Hansen Suss, Felipe Francisco Tuon. A carbapenem-resistant Acinetobacter baumannii outbreak associated with a polymyxin shortage during the COVID pandemic: an in vitro and biofilm analysis of synergy between meropenem, gentamicin and sulbactam. The Journal of antimicrobial chemotherapy. 2022 05; 77(6):1676-1684. doi: 10.1093/jac/dkac102. [PMID: 35368079]
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