malvidin (BioDeep_00000640860)

 

Secondary id: BioDeep_00000004150, BioDeep_00000269328

PANOMIX_OTCML-2023 PANOMIX-Anthocyanidin natural product


代谢物信息卡片


malvidin

化学式: C17H15O7+ (331.0818)
中文名称: 锦葵素
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 26.46%

分子结构信息

SMILES: C1(O)C=C2[O+]=C(C3=CC(OC)=C(O)C(OC)=C3)C(O)=CC2=C(O)C=1
InChI: InChI=1S/C17H14O7/c1-22-14-3-8(4-15(23-2)16(14)21)17-12(20)7-10-11(19)5-9(18)6-13(10)24-17/h3-7H,1-2H3,(H3-,18,19,20,21)/p+1

描述信息

An anthocyanidin cation that is delphinidin carrying methyl substituents at positions 3 and 5.

同义名列表

1 个代谢物同义名

malvidin



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

63 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 BCL2, CASP3, CAT, CHUK, MAPK14, MAPK8, NFE2L2, NLRP3, PRKAA2, PTGS1, PTGS2, VEGFA
Peripheral membrane protein 4 ACHE, GORASP1, PTGS1, PTGS2
Endoplasmic reticulum membrane 4 BCL2, HMOX1, PTGS1, PTGS2
Nucleus 12 ACHE, BCL2, CASP3, CHUK, HMOX1, MAPK14, MAPK8, MYB, NFE2L2, NLRP3, PRKAA2, VEGFA
cytosol 11 BCL2, CASP3, CAT, CHUK, HMOX1, MAPK14, MAPK8, MYB, NFE2L2, NLRP3, PRKAA2
dendrite 1 PRKAA2
centrosome 1 NFE2L2
nucleoplasm 8 CASP3, CHUK, HMOX1, MAPK14, MAPK8, MYB, NFE2L2, PRKAA2
RNA polymerase II transcription regulator complex 2 MYB, NFE2L2
Cell membrane 2 ACHE, TNF
Cytoplasmic side 2 GORASP1, HMOX1
Golgi apparatus membrane 2 GORASP1, NLRP3
Synapse 2 ACHE, MAPK8
cell surface 3 ACHE, TNF, VEGFA
glutamatergic synapse 2 CASP3, MAPK14
Golgi apparatus 6 ACHE, GORASP1, NFE2L2, PRKAA2, PTGS1, VEGFA
Golgi membrane 3 GORASP1, INS, NLRP3
neuromuscular junction 1 ACHE
neuronal cell body 3 CASP3, PRKAA2, TNF
Cytoplasm, cytosol 2 NFE2L2, NLRP3
plasma membrane 3 ACHE, NFE2L2, TNF
Membrane 8 ACHE, BCL2, CAT, HMOX1, MYB, NLRP3, PRKAA2, VEGFA
axon 2 MAPK8, PRKAA2
caveola 1 PTGS2
extracellular exosome 2 CAT, PTGS1
endoplasmic reticulum 5 BCL2, HMOX1, NLRP3, PTGS2, VEGFA
extracellular space 7 ACHE, CXCL8, HMOX1, IL6, INS, TNF, VEGFA
perinuclear region of cytoplasm 2 ACHE, HMOX1
adherens junction 1 VEGFA
mitochondrion 4 BCL2, CAT, MAPK14, NLRP3
protein-containing complex 3 BCL2, CAT, PTGS2
intracellular membrane-bounded organelle 2 CAT, PTGS1
Microsome membrane 2 PTGS1, PTGS2
postsynaptic density 1 CASP3
Secreted 6 ACHE, CXCL8, IL6, INS, NLRP3, VEGFA
extracellular region 9 ACHE, CAT, CXCL8, IL6, INS, MAPK14, NLRP3, TNF, VEGFA
cytoplasmic side of plasma membrane 1 CHUK
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, HMOX1
mitochondrial matrix 1 CAT
Extracellular side 1 ACHE
photoreceptor outer segment 1 PTGS1
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
CD40 receptor complex 1 CHUK
external side of plasma membrane 1 TNF
Secreted, extracellular space, extracellular matrix 1 VEGFA
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 1 TNF
pore complex 1 BCL2
focal adhesion 1 CAT
cis-Golgi network 1 GORASP1
extracellular matrix 1 VEGFA
Peroxisome 1 CAT
basement membrane 1 ACHE
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
secretory granule 1 VEGFA
nuclear speck 2 MAPK14, PRKAA2
Cytoplasm, cytoskeleton, microtubule organizing center 1 NLRP3
Inflammasome 1 NLRP3
interphase microtubule organizing center 1 NLRP3
NLRP3 inflammasome complex 1 NLRP3
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 2 PTGS1, PTGS2
chromatin 1 NFE2L2
mediator complex 1 NFE2L2
phagocytic cup 1 TNF
spindle pole 1 MAPK14
Lipid-anchor, GPI-anchor 1 ACHE
Endomembrane system 2 NLRP3, PTGS1
endosome lumen 1 INS
microtubule organizing center 1 NLRP3
cytoplasmic stress granule 1 PRKAA2
side of membrane 1 ACHE
myelin sheath 1 BCL2
ficolin-1-rich granule lumen 2 CAT, MAPK14
secretory granule lumen 3 CAT, INS, MAPK14
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 IL6, INS, PTGS2
nuclear matrix 1 MYB
platelet alpha granule lumen 1 VEGFA
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 2 GORASP1, INS
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
Single-pass type IV membrane protein 1 HMOX1
IkappaB kinase complex 1 CHUK
synaptic cleft 1 ACHE
protein-DNA complex 1 NFE2L2
basal dendrite 1 MAPK8
death-inducing signaling complex 1 CASP3
nucleotide-activated protein kinase complex 1 PRKAA2
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
BAD-BCL-2 complex 1 BCL2
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
[Isoform H]: Cell membrane 1 ACHE
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Fang Liu, Allen D Smith, Thomas T Y Wang, Quynhchi Pham, Lumei Cheung, Haiyan Yang, Robert W Li. Biological pathways via which the anthocyanin malvidin alleviated the murine colitis induced by Citrobacter rodentium. Food & function. 2023 Jan; 14(2):1048-1061. doi: 10.1039/d2fo02873e. [PMID: 36562464]
  • Chen Wang, Minna Zhang, Limin Wu, Fang Wang, Lingxi Li, Shuting Zhang, Baoshan Sun. Qualitative and quantitative analysis of phenolic compounds in blueberries and protective effects on hydrogen peroxide-induced cell injury. Journal of separation science. 2021 Jul; 44(14):2837-2855. doi: 10.1002/jssc.202001264. [PMID: 33939882]
  • Yu Qiao, Qiming Cheng, Yutong Zhang, Wei Yan, Fengyan Yi, Fengling Shi. Transcriptomic and chemical analyses to identify candidate genes involved in color variation of sainfoin flowers. BMC plant biology. 2021 Jan; 21(1):61. doi: 10.1186/s12870-021-02827-8. [PMID: 33482728]
  • Wenlan Zou, Chen Zhang, Xuefang Gu, Xiaohong Li, Huiming Zhu. Metformin in Combination with Malvidin Prevents Progression of Non-Alcoholic Fatty Liver Disease via Improving Lipid and Glucose Metabolisms, and Inhibiting Inflammation in Type 2 Diabetes Rats. Drug design, development and therapy. 2021; 15(?):2565-2576. doi: 10.2147/dddt.s307257. [PMID: 34168429]
  • Fernanda Mendes Rezende, Mads Hartvig Clausen, Magdalena Rossi, Cláudia Maria Furlan. The Regulation of Floral Colour Change in Pleroma raddianum (DC.) Gardner. Molecules (Basel, Switzerland). 2020 Oct; 25(20):. doi: 10.3390/molecules25204664. [PMID: 33066182]
  • Lianghua Xie, Jianling Mo, Jingdan Ni, Yang Xu, Hongming Su, Jiahong Xie, Wei Chen. Structure-based design of human pancreatic amylase inhibitors from the natural anthocyanin database for type 2 diabetes. Food & function. 2020 Apr; 11(4):2910-2923. doi: 10.1039/c9fo02885d. [PMID: 32219283]
  • Tânia C S P Pires, Maria Inês Dias, Márcio Carocho, João C M Barreira, Celestino Santos-Buelga, Lillian Barros, Isabel C F R Ferreira. Extracts from Vaccinium myrtillus L. fruits as a source of natural colorants: chemical characterization and incorporation in yogurts. Food & function. 2020 Apr; 11(4):3227-3234. doi: 10.1039/c9fo02890k. [PMID: 32215405]
  • Andreia Gapski, Trilicia M Gomes, Maiara A Bredun, Nayla E Ferreira-Lima, Fabiana Kalyne Ludka, Marilde T Bordignon-Luiz, Vívian Maria Burin. Digestion behavior and antidepressant-like effect promoted by acute administration of blueberry extract on mice. Food research international (Ottawa, Ont.). 2019 11; 125(?):108618. doi: 10.1016/j.foodres.2019.108618. [PMID: 31554107]
  • Liga Saulite, Kaspars Jekabsons, Maris Klavins, Ruta Muceniece, Una Riekstina. Effects of malvidin, cyanidin and delphinidin on human adipose mesenchymal stem cell differentiation into adipocytes, chondrocytes and osteocytes. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2019 Feb; 53(?):86-95. doi: 10.1016/j.phymed.2018.09.029. [PMID: 30668416]
  • Qianyu Yue, Lili Xu, Guangqing Xiang, Xin Yu, Yuxin Yao. Characterization of Gene Expression Profile, Phenolic Composition, and Antioxidant Capacity in Red-Fleshed Grape Berries and Their Wines. Journal of agricultural and food chemistry. 2018 Jul; 66(27):7190-7199. doi: 10.1021/acs.jafc.8b01323. [PMID: 29920074]
  • Hee Duk Oh, Duk Jun Yu, Sun Woo Chung, Sinath Chea, Hee Jae Lee. Abscisic acid stimulates anthocyanin accumulation in 'Jersey' highbush blueberry fruits during ripening. Food chemistry. 2018 Apr; 244(?):403-407. doi: 10.1016/j.foodchem.2017.10.051. [PMID: 29120800]
  • Abdul Basit Baba, Ramesh Nivetha, Indranil Chattopadhyay, Siddavaram Nagini. Blueberry and malvidin inhibit cell cycle progression and induce mitochondrial-mediated apoptosis by abrogating the JAK/STAT-3 signalling pathway. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2017 Nov; 109(Pt 1):534-543. doi: 10.1016/j.fct.2017.09.054. [PMID: 28974439]
  • Stefano Catola, Antonella Castagna, Marco Santin, Valentina Calvenzani, Katia Petroni, Andrea Mazzucato, Annamaria Ranieri. The dominant allele Aft induces a shift from flavonol to anthocyanin production in response to UV-B radiation in tomato fruit. Planta. 2017 Aug; 246(2):263-275. doi: 10.1007/s00425-017-2710-z. [PMID: 28516293]
  • Ganna Petruk, Anna Illiano, Rita Del Giudice, Assunta Raiola, Angela Amoresano, Maria Manuela Rigano, Renata Piccoli, Daria Maria Monti. Malvidin and cyanidin derivatives from açai fruit (Euterpe oleracea Mart.) counteract UV-A-induced oxidative stress in immortalized fibroblasts. Journal of photochemistry and photobiology. B, Biology. 2017 Jul; 172(?):42-51. doi: 10.1016/j.jphotobiol.2017.05.013. [PMID: 28527426]
  • Hui Wei, Hui Li, Shu-Ping Wan, Qiu-Tang Zeng, Long-Xian Cheng, Li-Li Jiang, Yu-Dong Peng. Cardioprotective Effects of Malvidin Against Isoproterenol-Induced Myocardial Infarction in Rats: A Mechanistic Study. Medical science monitor : international medical journal of experimental and clinical research. 2017 Apr; 23(?):2007-2016. doi: 10.12659/msm.902196. [PMID: 28445445]
  • Jessica D Mackert, Michael K McIntosh. Combination of the anthocyanidins malvidin and peonidin attenuates lipopolysaccharide-mediated inflammatory gene expression in primary human adipocytes. Nutrition research (New York, N.Y.). 2016 Dec; 36(12):1353-1360. doi: 10.1016/j.nutres.2016.11.003. [PMID: 27889107]
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  • Baolu Cui, Zongli Hu, Yanjie Zhang, Jingtao Hu, Wencheng Yin, Ye Feng, Qiaoli Xie, Guoping Chen. Anthocyanins and flavonols are responsible for purple color of Lablab purpureus (L.) sweet pods. Plant physiology and biochemistry : PPB. 2016 Jun; 103(?):183-90. doi: 10.1016/j.plaphy.2016.03.011. [PMID: 26995313]
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  • Venkadesaperumal Gopu, Sundar Kothandapani, Prathapkumar Halady Shetty. Quorum quenching activity of Syzygium cumini (L.) Skeels and its anthocyanin malvidin against Klebsiella pneumoniae. Microbial pathogenesis. 2015 Feb; 79(?):61-9. doi: 10.1016/j.micpath.2015.01.010. [PMID: 25637095]
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  • Kenjirou Ogawa, Yoshiki Kuse, Kazuhiro Tsuruma, Saori Kobayashi, Masamitsu Shimazawa, Hideaki Hara. Protective effects of bilberry and lingonberry extracts against blue light-emitting diode light-induced retinal photoreceptor cell damage in vitro. BMC complementary and alternative medicine. 2014 Apr; 14(?):120. doi: 10.1186/1472-6882-14-120. [PMID: 24690313]
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