Zymosterol (BioDeep_00000636698)

Main id: BioDeep_00000005819

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


5alpha-cholesta-8,24-dien-3beta-ol

化学式: C27H44O (384.3392)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1[C@]2(C)C3CC[C@]4(C)[C@@]([H])([C@]([H])(C)CC/C=C(\C)/C)CC[C@@]4([H])C=3CC[C@@]2([H])C[C@@H](O)C1
InChI: InChI=1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,19-21,23-24,28H,6,8-17H2,1-5H3/t19-,20+,21+,23-,24+,26+,27-/m1/s1

描述信息

COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

4 个代谢物同义名

Zymosterol; 5alpha-cholesta-8,24-dien-3beta-ol; ST 27:2;O; Zymosterol



数据库引用编号

14 个数据库交叉引用编号

分类词条

21 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 BDNF, DHCR24, ETS1, GPBAR1, NFE2L2, NR1H2, SND1
Peripheral membrane protein 3 CYP27A1, MBP, SQLE
Endoplasmic reticulum membrane 8 DHCR24, EBP, ERG28, HMGCR, HSD17B7, HSP90B1, MSMO1, SQLE
Mitochondrion membrane 1 CYP27A1
Nucleus 10 DHCR24, ETS1, ETS2, FEN1, HSP90B1, MBP, NFE2L2, NR1H2, NR1H4, SND1
cytosol 6 ETS2, HSP90B1, MBP, NFE2L2, NR1H2, SND1
dendrite 1 BDNF
centrosome 1 NFE2L2
nucleoplasm 6 ETS1, ETS2, FEN1, NFE2L2, NR1H2, NR1H4
RNA polymerase II transcription regulator complex 3 NFE2L2, NR1H2, NR1H4
Cell membrane 1 GPBAR1
Cytoplasmic side 1 MBP
Multi-pass membrane protein 5 EBP, ERG28, GPBAR1, HMGCR, MSMO1
Golgi apparatus membrane 1 DHCR24
Synapse 1 MBP
cell surface 1 MBP
Golgi apparatus 1 NFE2L2
Golgi membrane 1 DHCR24
mitochondrial inner membrane 1 CYP27A1
neuronal cell body 1 MBP
smooth endoplasmic reticulum 1 HSP90B1
synaptic vesicle 1 BDNF
Cytoplasm, cytosol 1 NFE2L2
plasma membrane 5 ETS2, GPBAR1, MBP, MSMO1, NFE2L2
Membrane 9 BDNF, DHCR24, ERG28, FEN1, HMGCR, HSP90B1, MSMO1, SND1, SQLE
axon 1 BDNF
extracellular exosome 3 HSP90B1, MBP, SND1
endoplasmic reticulum 7 DHCR24, EBP, ERG28, HMGCR, HSP90B1, MSMO1, SQLE
extracellular space 2 BDNF, IL17A
perinuclear region of cytoplasm 2 BDNF, HSP90B1
mitochondrion 3 CYP27A1, FEN1, HSD17B7
protein-containing complex 3 FEN1, HSP90B1, MBP
intracellular membrane-bounded organelle 1 SQLE
Microsome membrane 1 SQLE
Secreted 2 BDNF, IL17A
extracellular region 4 BDNF, HSP90B1, IL17A, MBP
Single-pass membrane protein 2 DHCR24, HSD17B7
mitochondrial matrix 1 CYP27A1
nuclear membrane 1 EBP
external side of plasma membrane 1 IL17A
cytoplasmic vesicle 1 EBP
nucleolus 1 FEN1
midbody 1 HSP90B1
Mitochondrion inner membrane 1 CYP27A1
focal adhesion 1 HSP90B1
peroxisomal membrane 1 HMGCR
collagen-containing extracellular matrix 2 HSP90B1, MBP
receptor complex 2 GPBAR1, NR1H4
chromatin 5 ETS1, ETS2, NFE2L2, NR1H2, NR1H4
mediator complex 1 NFE2L2
cell periphery 1 MBP
[Isoform 3]: Nucleus 2 MBP, NR1H4
Nucleus, nucleolus 1 FEN1
chromosome, telomeric region 1 FEN1
nuclear envelope 1 EBP
Nucleus envelope 1 EBP
Nucleus, nucleoplasm 1 FEN1
Melanosome 2 HSP90B1, SND1
euchromatin 1 NR1H4
myelin sheath 1 MBP
sperm plasma membrane 1 HSP90B1
Peroxisome membrane 1 HMGCR
ficolin-1-rich granule lumen 1 MBP
endoplasmic reticulum lumen 2 BDNF, HSP90B1
transport vesicle 2 ERG28, MBP
Sarcoplasmic reticulum lumen 1 HSP90B1
[Isoform 2]: Nucleus 1 NR1H4
[Isoform 1]: Nucleus 1 NR1H4
protein-DNA complex 1 NFE2L2
[Isoform 4]: Nucleus 1 NR1H4
endocytic vesicle lumen 1 HSP90B1
compact myelin 1 MBP
internode region of axon 1 MBP
endoplasmic reticulum chaperone complex 1 HSP90B1
[Bone marrow proteoglycan]: Secreted 1 MBP
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
[Isoform FENMIT]: Mitochondrion 1 FEN1
Myelin membrane 1 MBP
dense body 1 SND1
RNAi effector complex 1 SND1


文献列表

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  • Yanli Qi, Hui Liu, Jiayin Yu, Xiulai Chen, Liming Liu. Med15B Regulates Acid Stress Response and Tolerance in Candida glabrata by Altering Membrane Lipid Composition. Applied and environmental microbiology. 2017 09; 83(18):. doi: 10.1128/aem.01128-17. [PMID: 28710262]
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  • Katarzyna Hąc-Wydro, Paweł Wydro, Michał Flasiński. The comparison of zymosterol vs cholesterol membrane properties--the effect of zymosterol on lipid monolayers. Colloids and surfaces. B, Biointerfaces. 2014 Nov; 123(?):524-32. doi: 10.1016/j.colsurfb.2014.09.054. [PMID: 25444659]
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  • Mathieu Blanc, Wei Yuan Hsieh, Kevin A Robertson, Steven Watterson, Guanghou Shui, Paul Lacaze, Mizanur Khondoker, Paul Dickinson, Garwin Sing, Sara Rodríguez-Martín, Peter Phelan, Thorsten Forster, Birgit Strobl, Matthias Müller, Rudolph Riemersma, Timothy Osborne, Markus R Wenk, Ana Angulo, Peter Ghazal. Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis. PLoS biology. 2011 Mar; 9(3):e1000598. doi: 10.1371/journal.pbio.1000598. [PMID: 21408089]
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