(±)-Pelletierine (BioDeep_00000006078)

Main id: BioDeep_00000019536

 

human metabolite Endogenous


代谢物信息卡片


2-Propanone, 1-(2-piperidinyl)-, (+-) (9ci)

化学式: C8H15NO (141.1154)
中文名称: 石榴根皮碱
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=O)CC1CCCCN1
InChI: InChI=1S/C8H15NO/c1-7(10)6-8-4-2-3-5-9-8/h8-9H,2-6H2,1H3

描述信息

(±)-pelletierine, also known as (-)-isomer of isopelletierine or (+-)-1-(2-piperidinyl)-2-propanone, is a member of the class of compounds known as piperidines. Piperidines are compounds containing a piperidine ring, which is a saturated aliphatic six-member ring with one nitrogen atom and five carbon atoms (±)-pelletierine is soluble (in water) and an extremely weak acidic compound (based on its pKa). (±)-pelletierine can be found in pomegranate, which makes (±)-pelletierine a potential biomarker for the consumption of this food product.
(±)-Pelletierine is found in fruits. (±)-Pelletierine is an alkaloid from pomegranat

同义名列表

13 个代谢物同义名

2-Propanone, 1-(2-piperidinyl)-, (+-) (9ci); (+-)-1-(2-Piperidinyl)-2-propanone; (+-)-Isomer OF isopelletierine; 1-(piperidin-2-yl)propan-2-one; (-)-Isomer OF isopelletierine; 1-(2-Piperidinyl)acetone; 2-Acetonylpiperidine; (+-)-Pelletierine; (±)-Pelletierine; DL-Pelletierine; Isopelletierine; Pelletierine; Pelletierine



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

22 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ABL1, CYP2B6, CYP3A4, EGFR, ESR1, GSK3B, HSPA4, MAPK1, MAPK3, PRKCD
Peripheral membrane protein 5 ACHE, AOC1, CYP2B6, ESR1, PRKCD
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 3 CYP2B6, CYP3A4, EGFR
Nucleus 9 ABL1, ACHE, EGFR, ESR1, GSK3B, HSPA4, MAPK1, MAPK3, PRKCD
cytosol 7 ABL1, ESR1, GSK3B, HSPA4, MAPK1, MAPK3, PRKCD
dendrite 2 ABL1, GSK3B
nuclear body 1 ABL1
centrosome 2 GSK3B, MAPK1
nucleoplasm 6 ABL1, ESR1, GSK3B, MAPK1, MAPK3, PRKCD
Cell membrane 6 ACHE, AOC1, EGFR, ESR1, GSK3B, PRKCD
Cytoplasmic side 1 ESR1
ruffle membrane 1 EGFR
Early endosome membrane 1 EGFR
Synapse 3 ACHE, MAPK1, PRKCD
cell junction 1 EGFR
cell surface 2 ACHE, EGFR
glutamatergic synapse 4 ABL1, EGFR, GSK3B, MAPK3
Golgi apparatus 4 ACHE, ESR1, MAPK1, MAPK3
Golgi membrane 1 EGFR
growth cone 1 ABL1
neuromuscular junction 1 ACHE
neuronal cell body 1 ABL1
postsynapse 2 ABL1, GSK3B
Presynapse 1 GSK3B
endosome 1 EGFR
plasma membrane 10 ABL1, ACHE, AOC1, BCHE, EGFR, ESR1, GSK3B, MAPK1, MAPK3, PRKCD
Membrane 5 ACHE, CYP3A4, EGFR, ESR1, PRKCD
apical plasma membrane 1 EGFR
axon 1 GSK3B
basolateral plasma membrane 1 EGFR
caveola 2 MAPK1, MAPK3
extracellular exosome 3 AOC1, HSPA4, PRKCD
endoplasmic reticulum 1 PRKCD
extracellular space 4 ACHE, AOC1, BCHE, EGFR
perinuclear region of cytoplasm 4 ABL1, ACHE, EGFR, PRKCD
bicellular tight junction 1 AOC1
mitochondrion 6 ABL1, GSK3B, HSPA4, MAPK1, MAPK3, PRKCD
protein-containing complex 3 ABL1, EGFR, ESR1
intracellular membrane-bounded organelle 2 CYP2B6, CYP3A4
Microsome membrane 2 CYP2B6, CYP3A4
postsynaptic density 1 ABL1
Single-pass type I membrane protein 1 EGFR
Secreted 2 ACHE, BCHE
extracellular region 5 ACHE, AOC1, BCHE, MAPK1, PRKCD
Extracellular side 2 ACHE, AOC1
transcription regulator complex 1 ESR1
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 MAPK1
nuclear membrane 2 ABL1, EGFR
actin cytoskeleton 1 ABL1
beta-catenin destruction complex 1 GSK3B
nucleolus 1 ABL1
Wnt signalosome 1 GSK3B
Early endosome 2 MAPK1, MAPK3
cell-cell junction 1 PRKCD
Cytoplasm, perinuclear region 1 PRKCD
Membrane raft 1 EGFR
Cell junction, focal adhesion 2 MAPK1, MAPK3
Cytoplasm, cytoskeleton, spindle 1 MAPK1
focal adhesion 3 EGFR, MAPK1, MAPK3
spindle 1 MAPK1
Peroxisome 1 AOC1
basement membrane 1 ACHE
intracellular vesicle 1 EGFR
Late endosome 2 MAPK1, MAPK3
ruffle 1 ABL1
receptor complex 1 EGFR
neuron projection 1 PRKCD
chromatin 1 ESR1
mitotic spindle 1 MAPK1
cytoskeleton 2 MAPK1, MAPK3
Secreted, extracellular space 1 AOC1
blood microparticle 1 BCHE
Lipid-anchor, GPI-anchor 1 ACHE
nuclear envelope 1 MAPK3
Endomembrane system 1 PRKCD
Membrane, caveola 2 MAPK1, MAPK3
euchromatin 1 ESR1
side of membrane 1 ACHE
pseudopodium 2 MAPK1, MAPK3
basal plasma membrane 1 EGFR
synaptic membrane 1 EGFR
ficolin-1-rich granule lumen 1 MAPK1
endoplasmic reticulum lumen 3 BCHE, MAPK1, MAPK3
nuclear matrix 1 PRKCD
specific granule lumen 1 AOC1
azurophil granule lumen 2 MAPK1, PRKCD
nuclear envelope lumen 1 BCHE
clathrin-coated endocytic vesicle membrane 1 EGFR
[Isoform 1]: Nucleus 1 ESR1
Synapse, synaptosome 1 PRKCD
synaptic cleft 1 ACHE
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
endolysosome 1 PRKCD
[Isoform H]: Cell membrane 1 ACHE


文献列表

  • Juan Wang, Ze-Kun Zhang, Fang-Fang Jiang, Bo-Wen Qi, Ning Ding, Saw Yu Yu Hnin, Xiao Liu, Jun Li, Xiao-Hui Wang, Peng-Fei Tu, Ikuro Abe, Hiroyuki Morita, She-Po Shi. Deciphering the Biosynthetic Mechanism of Pelletierine in Lycopodium Alkaloid Biosynthesis. Organic letters. 2020 11; 22(21):8725-8729. doi: 10.1021/acs.orglett.0c03339. [PMID: 33104367]