Maackiain (BioDeep_00000600448)

PANOMIX_OTCML-2023

代谢物信息卡片

(-)-Maackiain

化学式: C16H12O5 (284.0684702)
中文名称: 高丽槐素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C2C(C3=C(O1)C=C(C=C3)O)OC4=CC5=C(C=C24)OCO5
InChI: InChI=1S/C16H12O5/c17-8-1-2-9-12(3-8)18-6-11-10-4-14-15(20-7-19-14)5-13(10)21-16(9)11/h1-5,11,16-17H,6-7H2

描述信息

Widespread in the Leguminosae subfamily. Constituent of Trifolium pratense (red clover). (-)-Maackiain is found in many foods, some of which are nectarine, chickpea, alaska blueberry, and adzuki bean.
(-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts[1].
(-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts[1].
(-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts[1].
(-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts[1].

同义名列表

3 个代谢物同义名

(-)-Maackiain; Maackiain; (-?)?-Maackiain

数据库引用编号

8 个数据库交叉引用编号

ChEBI: CHEBI:99
KEGGdrug: D85120
PubChem: 91510
Metlin: METLIN44622
ChEMBL: CHEMBL334918
foodb: FDB015548
CAS: 2035-15-6
medchemexpress: HY-N6051

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

151 个相关的物种来源信息

318067 - Artemisia indica: 10.1021/NP980041X
149635 - Bobgunnia madagascariensis: 10.1039/J39690001109
390493 - Caragana acanthophylla: 10.1515/ZNC-1979-3-424
1641258 - Caragana altaica: 10.1515/ZNC-1979-3-424
626686 - Caragana ambigua: 10.1515/ZNC-1979-3-424
20484 - Caragana arborescens: 10.1515/ZNC-1979-3-424
626687 - Caragana aurantiaca: 10.1515/ZNC-1979-3-424
626688 - Caragana boisii: 10.1515/ZNC-1979-3-424
626672 - Caragana brevispina: 10.1515/ZNC-1979-3-424
626677 - Caragana conferta: 10.1515/ZNC-1979-3-424
626689 - Caragana decorticans: 10.1515/ZNC-1979-3-424
403829 - Caragana densa: 10.1515/ZNC-1979-3-424
390495 - Caragana erinacea: 10.1515/ZNC-1979-3-424
483144 - Caragana franchetiana: 10.1515/ZNC-1979-3-424
47643 - Caragana frutex: 10.1515/ZNC-1979-3-424
1913450 - Caragana fruticosa: 10.1515/ZNC-1979-3-424
626678 - Caragana gerardiana: 10.1515/ZNC-1979-3-424
144173 - Caragana grandiflora: 10.1515/ZNC-1979-3-424
283153 - Caragana jubata: 10.1515/ZNC-1979-3-424
626680 - Caragana kirghisorum: 10.1515/ZNC-1979-3-424
626681 - Caragana laeta: 10.1515/ZNC-1979-3-424
220690 - Caragana microphylla: 10.1515/ZNC-1979-3-424
626682 - Caragana pekinensis: 10.1515/ZNC-1979-3-424
626683 - Caragana pleiophylla: 10.1515/ZNC-1979-3-424
1641263 - Caragana pumila: 10.1515/ZNC-1979-3-424
626690 - Caragana pygmaea: 10.1515/ZNC-1979-3-424
403832 - Caragana sinica: 10.1515/ZNC-1979-3-424
626692 - Caragana spinosa: 10.1515/ZNC-1979-3-424
390502 - Caragana stenophylla: 10.1515/ZNC-1979-3-424
626695 - Caragana tangutica: 10.1515/ZNC-1979-3-424
390503 - Caragana tibetica: 10.1515/ZNC-1979-3-424
390504 - Caragana tragacanthoides: 10.1515/ZNC-1979-3-424
575199 - Caragana turkestanica: 10.1515/ZNC-1979-3-424
626696 - Caragana ussuriensis: 10.1515/ZNC-1979-3-424
390505 - Caragana zahlbruckneri: 10.1515/ZNC-1979-3-424
242878 - Cicer anatolicum:
3827 - Cicer arietinum:
90899 - Cicer bijugum:
200948 - Cicer canariense: 10.1016/S0031-9422(97)00798-X
107682 - Cicer chorassanicum:
92720 - Cicer cuneatum:
90897 - Cicer echinospermum:
92719 - Cicer judaicum:
200949 - Cicer macracanthum:
224826 - Cicer microphyllum: 10.1016/S0031-9422(97)00798-X
242879 - Cicer montbretii: 10.1016/0305-1978(81)90030-2
242870 - Cicer nuristanicum: 10.1016/S0031-9422(97)00798-X
242871 - Cicer oxyodon: 10.1016/S0031-9422(97)00798-X
47088 - Cicer pinnatifidum:
242872 - Cicer pungens: 10.1016/0305-1978(81)90030-2
380786 - Cicer rechingeri: 10.1016/0305-1978(81)90030-2
90898 - Cicer reticulatum:
242873 - Cicer songaricum: 10.1016/0305-1978(81)90030-2
92718 - Cicer yamashitae:
247908 - Cladrastis platycarpa: 10.1021/NP50068A037
1645771 - Dahlstedtia pentaphylla: 10.1016/0031-9422(88)80277-2
62116 - Dahlstedtia pinnata: 10.1016/0031-9422(88)80277-2
1353471 - Dalbergia sericea: 10.1515/ZNC-1979-7-823
1225674 - Derris cuneifolia: 10.3987/COM-95-7069
597292 - Diplotropis purpurea: 10.1016/0031-9422(73)85046-0
256638 - Euchresta formosana:
53879 - Euchresta horsfieldii:
256639 - Euchresta japonica: 10.1016/0031-9422(80)85077-1
49827 - Glycyrrhiza glabra L.: -
74614 - Glycyrrhiza inflata Bat.: -
74859 - Glycyrrhiza pallidiflora: 10.1016/S0031-9422(01)00268-0
74613 - Glycyrrhiza uralensis Fisch.: -
3854 - Lathyrus aphaca: 10.1016/S0031-9422(00)82217-7
3856 - Lathyrus cicera: 10.1016/S0031-9422(00)82217-7
1276771 - Lathyrus grandiflorus: 10.1016/S0031-9422(00)82217-7
3857 - Lathyrus hirsutus: 10.1016/S0031-9422(00)82217-7
313096 - Lathyrus linifolius: 10.1016/S0031-9422(00)82217-7
3858 - Lathyrus ochrus: 10.1016/S0031-9422(00)82217-7
313104 - Lathyrus palustris: 10.1016/S0031-9422(00)82217-7
1276795 - Lathyrus roseus: 10.1016/S0031-9422(00)82217-7
313117 - Lathyrus sylvestris: 10.1016/S0031-9422(00)82217-7
49829 - Lathyrus tuberosus: 10.1016/S0031-9422(00)82217-7
1221114 - Leptolobium bijugum: 10.1016/S0305-1978(01)00055-2
3925 - Lonchocarpus: 10.1002/PTR.889
1225672 - Lonchocarpus sericeus: 10.3987/COM-02-9678
37501 - Maackia amurensis:
2614529 - Maackia tenuifolia: 10.1021/NP970173A
132451 - Millettia pulchra: 10.1016/S0031-9422(00)80349-0
54460 - Mundulea sericea: 10.1515/ZNC-1979-7-823
185713 - Nanhaia speciosa: 10.3987/COM-02-9678
797985 - Ononis alopecuroides: 10.1016/0305-1978(82)90035-7
797992 - Ononis baetica: 10.1016/0305-1978(82)90035-7
200953 - Ononis biflora: 10.1016/0305-1978(82)90035-7
798006 - Ononis hispida: 10.1016/0305-1978(82)90035-7
798013 - Ononis minutissima: 10.1016/0305-1978(82)90035-7
361878 - Ononis mitissima: 10.1016/0305-1978(82)90035-7
200954 - Ononis natrix: 10.1016/0305-1978(82)90035-7
798017 - Ononis oligophylla: 10.1016/0305-1978(82)90035-7
798022 - Ononis pinnata: 10.1016/0305-1978(82)90035-7
798039 - Ononis speciosa: 10.1016/0305-1978(82)90035-7
58890 - Ononis spinosa: 10.1016/0305-1978(82)90035-7
798051 - Ononis vaginalis: 10.1055/S-2001-14325
798053 - Ononis variegata: 10.1016/0305-1978(82)90035-7
1479707 - Oxytropis falcata: 10.1021/NP100339U
1929974 - Pericopsis laxiflora: 10.1002/PCA.2800060603
3888 - Pisum sativum: 10.1016/S0031-9422(82)85025-5
33090 - Plants: -
2816372 - Platyosprion platycarpum: 10.1021/NP50068A037
2651278 - Pongamia pinnata var. pinnata: 10.1016/J.PHYTOCHEM.2006.03.019
248527 - Psorothamnus arborescens: 10.1021/NP0502600
3896 - Sophora: 10.1016/S0031-9422(97)00802-9
200492 - Sophora alopecuroides:
171561 - Sophora chrysophylla: 10.1248/CPB.38.1712
49840 - Sophora flavescens:
2891946 - Sophora franchetiana: 10.1248/CPB.29.532
479969 - Sophora fraseri: 10.1016/S0031-9422(00)90868-9
49841 - Sophora jaubertii: 10.1016/0031-9422(94)00720-E
70607 - Sophora microphylla: 10.1071/C96109
1323965 - Sophora moorcroftiana: 10.1248/CPB.36.2220
76398 - Sophora prostrata: 10.1016/0031-9422(94)00721-5
171567 - Sophora tetraptera:
256637 - Sophora tomentosa: 10.1248/CPB.38.2756
714503 - Sophora tonkinensis: 10.1002/JSSC.201400691
714503 - Sophora tonkinensis Gagnep.: -
3897 - Styphnolobium japonicum:
149671 - Swartzia apetala: 10.1590/S0102-695X2009000300005
1871529 - Tephrosia angustissima:
228354 - Tephrosia purpurea:
62125 - Tephrosia villosa: 10.1016/0031-9422(80)85079-5
1089629 - Tephrosia virginiana: 10.1016/0031-9422(80)85079-5
361559 - Trifolium africanum: 10.1515/ZNC-1990-7-814
97007 - Trifolium alpestre: 10.1016/0305-1978(78)90010-8
74505 - Trifolium angulatum: 10.1515/ZNC-1990-7-814
361898 - Trifolium bullatum: 10.1515/ZNC-1990-7-814
361908 - Trifolium dalmaticum: 10.1515/ZNC-1990-7-814
97020 - Trifolium diffusum: 10.1016/0305-1978(78)90010-8
361924 - Trifolium heldreichianum: 10.1515/ZNC-1990-7-814
361562 - Trifolium ligusticum: 10.1016/0305-1978(78)90010-8
97028 - Trifolium medium: 10.1016/0305-1978(78)90010-8
361943 - Trifolium miegeanum: 10.1515/ZNC-1990-7-814
74522 - Trifolium montanum: 10.1016/0305-1978(78)90010-8
361950 - Trifolium oliganthum: 10.1515/ZNC-1990-7-814
74525 - Trifolium ornithopodioides: 10.1016/0305-1978(78)90010-8
97031 - Trifolium pallidum: 10.1515/ZNC-1990-7-814
200958 - Trifolium patulum: 10.1515/ZNC-1990-7-814
361956 - Trifolium pauciflorum: 10.1515/ZNC-1990-7-814
361961 - Trifolium phleoides: 10.1515/ZNC-1990-7-814
361966 - Trifolium pignantii: 10.1515/ZNC-1990-7-814
57577 - Trifolium pratense: 10.1093/JEXBOT/52.357.681
97034 - Trifolium purpureum: 10.1016/0305-1978(78)90010-8
1534692 - Trifolium saxatile: 10.1515/ZNC-1990-7-814
361995 - Trifolium trichocephalum: 10.1515/ZNC-1990-7-814
361998 - Trifolium vavilovii: 10.1515/ZNC-1990-7-814
183318 - Ulex minor: 10.1515/ZNC-2000-7-804
49854 - Ulex parviflorus: 10.1016/S0031-9422(97)01090-X
58847 - Virgilia oroboides:

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Saveta G Mladenova, Monika N Todorova, Martina S Savova, Milen I Georgiev, Liliya V Mihaylova. Maackiain Mimics Caloric Restriction through aak-2-Mediated Lipid Reduction in Caenorhabditis elegans. International journal of molecular sciences. 2023 Dec; 24(24):. doi: 10.3390/ijms242417442. [PMID: 38139270]
Xing Jiang, Xiaonan Yang, Yanxia Shi, Yan Long, Wenqing Su, Wendong He, Kunhua Wei, Jianhua Miao. Maackiain inhibits proliferation and promotes apoptosis of nasopharyngeal carcinoma cells by inhibiting the MAPK/Ras signaling pathway. Chinese journal of natural medicines. 2023 Mar; 21(3):185-196. doi: 10.1016/s1875-5364(23)60420-0. [PMID: 37003641]
Janakiraman V, Sudhan M, Abubakar Wani, Sheikh F Ahmad, Ahmed Nadeem, Ashutosh Sharma, Shiek S S J Ahmed. Pharmacoscreening, molecular dynamics, and quantum mechanics of inermin from Panax ginseng: a crucial molecule inhibiting exosomal protein target associated with coronary artery disease progression. PeerJ. 2023; 11(?):e16481. doi: 10.7717/peerj.16481. [PMID: 38077444]
Saveta G Mladenova, Martina S Savova, Andrey S Marchev, Claudio Ferrante, Giustino Orlando, Martin Wabitsch, Milen I Georgiev. Anti-adipogenic activity of maackiain and ononin is mediated via inhibition of PPARγ in human adipocytes. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 May; 149(?):112908. doi: 10.1016/j.biopha.2022.112908. [PMID: 35367764]
Na Lu, Guojun Tan, Hongling Tan, Xing Zhang, Yunling Lv, Xiujuan Song, Daofeng You, Ziyuan Gao. Maackiain Prevents Amyloid-Beta-Induced Cellular Injury via Priming PKC-Nrf2 Pathway. BioMed research international. 2022; 2022(?):4243210. doi: 10.1155/2022/4243210. [PMID: 35782063]
Wen-Lin Yuan, Zheng-Rui Huang, Si-Jia Xiao, Ji Ye, Wei-Dong Zhang, Yun-Heng Shen. [Metabolites and metabolic pathways of maackiain in rats based on UPLC-Q-TOF-MS]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2021 Dec; 46(23):6278-6288. doi: 10.19540/j.cnki.cjcmm.20210902.201. [PMID: 34951255]
Guangfei Wei, Yongzhong Chen, Xiaotong Guo, Jianhe Wei, Linlin Dong, Shilin Chen. Biosyntheses characterization of alkaloids and flavonoids in Sophora flavescens by combining metabolome and transcriptome. Scientific reports. 2021 04; 11(1):7388. doi: 10.1038/s41598-021-86970-0. [PMID: 33795823]
Jiahong Guo, Junying Li, Hua Wei, Zhaozhi Liang. Maackiain Protects the Kidneys of Type 2 Diabetic Rats via Modulating the Nrf2/HO-1 and TLR4/NF-κB/Caspase-3 Pathways. Drug design, development and therapy. 2021; 15(?):4339-4358. doi: 10.2147/dddt.s326975. [PMID: 34703210]
Jin-Won Huh, Jung-Hoon Lee, Eekhyoung Jeon, Hyung Won Ryu, Sei-Ryang Oh, Kyung-Seop Ahn, Hyun Sik Jun, Un-Hwan Ha. Maackiain, a compound derived from Sophora flavescens, increases IL-1β production by amplifying nigericin-mediated inflammasome activation. FEBS open bio. 2020 08; 10(8):1482-1491. doi: 10.1002/2211-5463.12899. [PMID: 32428336]
Yan Li, Jie-Wei Wu, Hai-Bo Tan, Bai-Lin Li, Sheng-Xiang Qiu. Three new pterocarpans from the aerial parts of Abrus Precatorius. Natural product research. 2020 Jul; 34(13):1836-1844. doi: 10.1080/14786419.2018.1564293. [PMID: 31328559]
Soyoung Kim, Yu Jeong Jeong, Su Hyun Park, Sung-Chul Park, Saet Buyl Lee, Jiyoung Lee, Suk Weon Kim, Bo-Keun Ha, Hyun-Soon Kim, HyeRan Kim, Young Bae Ryu, Jae Cheol Jeong, Cha Young Kim. The Synergistic Effect of Co-Treatment of Methyl Jasmonate and Cyclodextrins on Pterocarpan Production in Sophora flavescens Cell Cultures. International journal of molecular sciences. 2020 May; 21(11):. doi: 10.3390/ijms21113944. [PMID: 32486319]
Yannan Li, Jing Ning, Yan Wang, Chao Wang, Chengpeng Sun, Xiaokui Huo, Zhenlong Yu, Lei Feng, Baojing Zhang, Xiangge Tian, Xiaochi Ma. Drug interaction study of flavonoids toward CYP3A4 and their quantitative structure activity relationship (QSAR) analysis for predicting potential effects. Toxicology letters. 2018 Sep; 294(?):27-36. doi: 10.1016/j.toxlet.2018.05.008. [PMID: 29753067]
Achara Raksat, Wisanu Maneerat, Raymond J Andersen, Stephen G Pyne, Surat Laphookhieo. Antibacterial Prenylated Isoflavonoids from the Stems of Millettia extensa. Journal of natural products. 2018 08; 81(8):1835-1840. doi: 10.1021/acs.jnatprod.8b00321. [PMID: 30106294]
Xinzhou Yang, Shihao Deng, Mi Huang, Jialin Wang, Li Chen, Mingrui Xiong, Jie Yang, Sijiang Zheng, Xinhua Ma, Ping Zhao, Yunjiang Feng. Chemical constituents from Sophora tonkinensis and their glucose transporter 4 translocation activities. Bioorganic & medicinal chemistry letters. 2017 03; 27(6):1463-1466. doi: 10.1016/j.bmcl.2017.01.078. [PMID: 28236591]
Hyun Woo Lee, Hyung Won Ryu, Myung-Gyun Kang, Daeui Park, Sei-Ryang Oh, Hoon Kim. Potent selective monoamine oxidase B inhibition by maackiain, a pterocarpan from the roots of Sophora flavescens. Bioorganic & medicinal chemistry letters. 2016 10; 26(19):4714-4719. doi: 10.1016/j.bmcl.2016.08.044. [PMID: 27575476]
Nóra Gampe, András Darcsi, Szilvia Lohner, Szabolcs Béni, László Kursinszki. Characterization and identification of isoflavonoid glycosides in the root of Spiny restharrow (Ononis spinosa L.) by HPLC-QTOF-MS, HPLC-MS/MS and NMR. Journal of pharmaceutical and biomedical analysis. 2016 May; 123(?):74-81. doi: 10.1016/j.jpba.2016.01.058. [PMID: 26874257]
Lotfi Ghribi, Pierre Waffo-Téguo, Stéphanie Cluzet, Axel Marchal, Jessica Marques, Jean-Michel Mérillon, Hichem Ben Jannet. Isolation and structure elucidation of bioactive compounds from the roots of the Tunisian Ononis angustissima L. Bioorganic & medicinal chemistry letters. 2015 Sep; 25(18):3825-30. doi: 10.1016/j.bmcl.2015.07.076. [PMID: 26248805]
Taijun Yin, Guanyi Yang, Yong Ma, Beibei Xu, Ming Hu, Ming You, Song Gao. Developing an activity and absorption-based quality control platform for Chinese traditional medicine: Application to Zeng-Sheng-Ping(Antitumor B). Journal of ethnopharmacology. 2015 Aug; 172(?):195-201. doi: 10.1016/j.jep.2015.06.019. [PMID: 26099633]
Patrícia C Bezerra-Silva, Jefferson C Santos, Geanne K N Santos, Kamilla A Dutra, Andrea L B D Santana, Claudia A Maranhão, Márcia S Nascimento, Daniela M A F Navarro, Lothar W Bieber. Extract of Bowdichia virgilioides and maackiain as larvicidal agent against Aedes aegypti mosquito. Experimental parasitology. 2015 Jun; 153(?):160-4. doi: 10.1016/j.exppara.2015.03.018. [PMID: 25819294]
Soo Min Jang, Soo Hyeon Bae, Woong-Kee Choi, Jung Bae Park, Doyun Kim, Jee Sun Min, Hunseung Yoo, Minseok Kang, Keun Ho Ryu, Soo Kyung Bae. Pharmacokinetic properties of trifolirhizin, (-)-maackiain, (-)-sophoranone and 2-(2,4-dihydroxyphenyl)-5,6-methylenedioxybenzofuran after intravenous and oral administration of Sophora tonkinensis extract in rats. Xenobiotica; the fate of foreign compounds in biological systems. 2015; 45(12):1092-104. doi: 10.3109/00498254.2015.1041181. [PMID: 26068519]
Hunseung Yoo, Hee-Sung Chae, Young-Mi Kim, Minseok Kang, Keun Ho Ryu, Hee Chul Ahn, Kee Dong Yoon, Young-Won Chin, Jinwoong Kim. Flavonoids and arylbenzofurans from the rhizomes and roots of Sophora tonkinensis with IL-6 production inhibitory activity. Bioorganic & medicinal chemistry letters. 2014 Dec; 24(24):5644-5647. doi: 10.1016/j.bmcl.2014.10.077. [PMID: 25467151]
Hunseung Yoo, Keun Ho Ryu, Soo Kyung Bae, Jinwoong Kim. Simultaneous determination of trifolirhizin, (-)-maackiain, (-)-sophoranone, and 2-(2,4-dihydroxyphenyl)-5,6-methylenedioxybenzofuran from Sophora tonkinensis in rat plasma by liquid chromatography with tandem mass spectrometry and its application to a pharmacokinetic study. Journal of separation science. 2014 Nov; 37(22):3235-44. doi: 10.1002/jssc.201400691. [PMID: 25156071]
Chong Wu, Gui-Hua Deng, Chao-Zhan Lin, Chen-Chen Zhu. [Simultaneous determination of 4 alkaloids and a flavonoid in Picrasmae Ramulus et Folium by RP-HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2014 May; 39(9):1656-9. doi: . [PMID: 25095379]
Diana C Rueda, Maria De Mieri, Steffen Hering, Matthias Hamburger. HPLC-based activity profiling for GABAA receptor modulators in Adenocarpus cincinnatus. Journal of natural products. 2014 Mar; 77(3):640-9. doi: 10.1021/np500016z. [PMID: 24571311]
Quan Liu, Rui Xu, Zhiqiang Yan, Hui Jin, Haiyan Cui, Liqin Lu, Denghong Zhang, Bo Qin. Phytotoxic allelochemicals from roots and root exudates of Trifolium pratense. Journal of agricultural and food chemistry. 2013 Jul; 61(26):6321-7. doi: 10.1021/jf401241e. [PMID: 23738849]
Yian Wang, Ruisheng Yao, Song Gao, Weidong Wen, Yinqiu Du, Eva Szabo, Ming Hu, Ronald A Lubet, Ming You. Chemopreventive effect of a mixture of Chinese Herbs (antitumor B) on chemically induced oral carcinogenesis. Molecular carcinogenesis. 2013 Jan; 52(1):49-56. doi: 10.1002/mc.20877. [PMID: 22086836]
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