(5Z)-(15S)-11alpha-Hydroxy-9,15-dioxoprostanoate (BioDeep_00000005611)

Main id: BioDeep_00000628870

 

human metabolite Endogenous


代谢物信息卡片


(5Z)-7-[(1S,2S,3S)-3-hydroxy-5-oxo-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid

化学式: C20H32O5 (352.225)
中文名称: 13,14-二氢-15-酮前列腺素e2
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCC(=O)CCC1C(CC(=O)C1CC=CCCCC(=O)O)O
InChI: InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,16-17,19,23H,2-3,5-6,8-14H2,1H3,(H,24,25)/b7-4-/t16-,17-,19-/m0/s1

描述信息

(5Z)-(15S)-11alpha-Hydroxy-9,15-dioxoprostanoate is a precursor in producing (5Z)-(15S)-11-a-hydroxy-9,15-dioxoprosta-13-enoate in the presence of NADP+, in this reaction (5Z)-(15S)-11alpha-Hydroxy-9,15-dioxoprostanoate is oxidized. [HMDB]
(5Z)-(15S)-11alpha-Hydroxy-9,15-dioxoprostanoate is a precursor in producing (5Z)-(15S)-11-a-hydroxy-9,15-dioxoprosta-13-enoate in the presence of NADP+, in this reaction (5Z)-(15S)-11alpha-Hydroxy-9,15-dioxoprostanoate is oxidized.

同义名列表

18 个代谢物同义名

(5Z)-7-[(1S,2S,3S)-3-hydroxy-5-oxo-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid; (5Z)-7-[(1R,2R,3R)-3-hydroxy-5-oxo-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid; (5Z)-7-[(1S,2S,3S)-3-Hydroxy-5-oxo-2-(3-oxooctyl)cyclopentyl]hept-5-enoate; (5Z)-(15S)-11alpha-Hydroxy-9,15-dioxoprostanoic acid; (5Z)-11alpha-Hydroxy-9,15-dioxoprost-5-enoic acid; (5Z)-(15S)-11Α-hydroxy-9,15-dioxoprostanoic acid; (5Z)-(15S)-11alpha-Hydroxy-9,15-dioxoprostanoate; (5Z)-(15S)-11a-Hydroxy-9,15-dioxoprostanoic acid; (5Z)-11alpha-Hydroxy-9,15-dioxoprost-5-enoate; (5Z)-(15S)-11Α-hydroxy-9,15-dioxoprostanoate; (5Z)-(15S)-11a-Hydroxy-9,15-dioxoprostanoate; 9,15-dioxo-11R-hydroxy-5Z-prostenoic acid; alpha-Hydroxy-9,15-dioxoprostanoic acid; 13,14-dihydro-15-keto-Prostaglandin E2; 13,14-dihydro-15-keto Prostaglandin E2; alpha-Hydroxy-9,15-dioxoprostanoate; 13,14-dihydro-15-keto-PGE2; DHK-PGE2



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

3 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(3)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ALB, HPGD, PTGS1, PTGS2, TNK1
Golgi apparatus, trans-Golgi network membrane 1 LRBA
Peripheral membrane protein 5 AP1S2, ERVW-1, PTGS1, PTGS2, TNK1
Endoplasmic reticulum membrane 4 CD4, LRBA, PTGS1, PTGS2
Nucleus 2 ALB, CIITA
cytosol 7 ALB, AP1S2, CIITA, GOLPH3, HBB, HPGD, LRBA
trans-Golgi network 1 GOLPH3
centrosome 1 ALB
nucleoplasm 2 CIITA, HPGD
Cell membrane 5 CD4, GOLPH3, LRBA, SLC7A1, TNF
Cytoplasmic side 1 AP1S2
Multi-pass membrane protein 2 SLC7A1, TPRA1
cell surface 2 CIITA, TNF
Golgi apparatus 5 ALB, AP1S2, GOLPH3, LRBA, PTGS1
Golgi membrane 3 AP1S2, GOLPH3, INS
lysosomal membrane 2 AP1S2, LRBA
neuronal cell body 1 TNF
endosome 1 GOLPH3
plasma membrane 10 CD4, ERVW-1, GOLPH3, IFNLR1, LRBA, REN, SLC7A1, TNF, TNK1, TPRA1
Membrane 8 GOLPH3, HBB, IFNLR1, LRBA, REN, SLC7A1, TNK1, TPRA1
apical plasma membrane 1 SLC7A1
basolateral plasma membrane 2 HPGD, SLC7A1
caveola 1 PTGS2
extracellular exosome 4 ALB, HBB, HPGD, PTGS1
Lysosome membrane 1 LRBA
endoplasmic reticulum 2 ALB, PTGS2
extracellular space 7 ALB, HBB, IL2, IL6, INS, REN, TNF
mitochondrion 1 GOLPH3
protein-containing complex 3 ALB, PTGS2, SLC7A1
intracellular membrane-bounded organelle 3 AP1S2, GOLPH3, PTGS1
Microsome membrane 2 PTGS1, PTGS2
Single-pass type I membrane protein 3 CD4, ERVW-1, IFNLR1
Secreted 5 ALB, IL2, IL6, INS, REN
extracellular region 7 ALB, HBB, IL2, IL6, INS, REN, TNF
Single-pass membrane protein 1 LRBA
anchoring junction 1 ALB
photoreceptor outer segment 1 PTGS1
external side of plasma membrane 2 CD4, TNF
Early endosome 2 AP1S2, CD4
Membrane, clathrin-coated pit 1 AP1S2
apical part of cell 1 REN
clathrin-coated pit 1 AP1S2
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 2 CD4, TNF
Nucleus, PML body 1 CIITA
PML body 1 CIITA
mitochondrial intermembrane space 1 GOLPH3
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 2 PTGS1, PTGS2
ciliary basal body 1 ALB
phagocytic cup 1 TNF
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 2 ALB, HBB
Endomembrane system 2 AP1S2, PTGS1
endosome lumen 1 INS
Cytoplasmic vesicle membrane 1 AP1S2
Golgi cisterna membrane 1 GOLPH3
basal plasma membrane 1 SLC7A1
trans-Golgi network membrane 1 AP1S2
ficolin-1-rich granule lumen 1 HBB
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 5 ALB, CD4, IL6, INS, PTGS2
platelet alpha granule lumen 1 ALB
tertiary granule lumen 1 HBB
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
Golgi cisterna 1 GOLPH3
clathrin-coated endocytic vesicle membrane 1 CD4
[Transmembrane protein]: Cell membrane 1 ERVW-1
[Surface protein]: Cell membrane 1 ERVW-1
AP-type membrane coat adaptor complex 1 AP1S2
membrane coat 1 AP1S2
AP-1 adaptor complex 1 AP1S2
hemoglobin complex 1 HBB
endocytic vesicle lumen 1 HBB
haptoglobin-hemoglobin complex 1 HBB
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 1 CD4
interleukin-6 receptor complex 1 IL6
ciliary transition fiber 1 ALB
interleukin-28 receptor complex 1 IFNLR1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
[Syncytin-1]: Virion 1 ERVW-1


文献列表

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