4-Nitrophenyl β-D-galactopyranoside (BioDeep_00000005527)

   


代谢物信息卡片


4-Nitrophenol-alpha-D-galactopyranoside

化学式: C12H15NO8 (301.0798)
中文名称: 对硝基苯基-β-D-吡喃半乳糖苷, 4-硝基苯基-β-D-吡喃半乳糖苷
谱图信息: 最多检出来源 Homo sapiens(not specific) 4.35%

分子结构信息

SMILES: C1=CC(=CC=C1[N+](=O)[O-])OC2C(C(C(C(O2)CO)O)O)O
InChI: InChI=1S/C12H15NO8/c14-5-8-9(15)10(16)11(17)12(21-8)20-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8-,9+,10+,11-,12-/m1/s1

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D000345 - Affinity Labels

同义名列表

5 个代谢物同义名

4-Nitrophenyl-beta-D-galactopyranoside; 4-Nitrophenyl β-D-galactopyranoside; 4-Nitrophenol-alpha-D-galactopyranoside; p-Nitrophenyl-beta-D-glucopyranoside; 4-Nitrophenyl-beta-D-galactopyranoside



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 CAT, DES, DTNB, HPGDS, PDLIM4, TRIM35
Golgi apparatus, trans-Golgi network membrane 1 LRBA
Peripheral membrane protein 3 COQ10A, GBA1, PDLIM4
Endoplasmic reticulum membrane 1 LRBA
Nucleus 5 DES, DTNB, PDLIM4, RBL2, TRIM35
cytosol 7 CAT, DES, HPGDS, LIPE, LRBA, NGF, RBL2
dendrite 2 DTNB, NGF
trans-Golgi network 1 GBA1
nucleoplasm 3 ATP2B1, HPGDS, RBL2
Cell membrane 3 ATP2B1, LIPE, LRBA
Cytoplasmic side 1 PDLIM4
lamellipodium 1 PDLIM4
Early endosome membrane 1 PDLIM4
Multi-pass membrane protein 1 ATP2B1
Synapse 3 ATP2B1, DTNB, PDLIM4
cell surface 1 SDC1
glutamatergic synapse 1 ATP2B1
Golgi apparatus 2 GBA1, LRBA
lysosomal membrane 3 GAA, GBA1, LRBA
mitochondrial inner membrane 1 COQ10A
neuromuscular junction 1 DES
postsynapse 1 DTNB
presynaptic membrane 1 ATP2B1
sarcolemma 1 DES
synaptic vesicle 1 NGF
Cytoplasm, cytosol 1 LIPE
Lysosome 2 GAA, GBA1
plasma membrane 7 ATP2B1, DTNB, F2, GAA, IGHE, LRBA, SDC1
synaptic vesicle membrane 1 ATP2B1
Membrane 7 ATP2B1, CAT, CYB5D2, GAA, LIPE, LRBA, SDC1
axon 1 NGF
basolateral plasma membrane 1 ATP2B1
caveola 1 LIPE
extracellular exosome 9 A2M, ATP2B1, CAT, DES, F2, GAA, GBA1, RBL2, SDC1
Lysosome membrane 3 GAA, GBA1, LRBA
Lumenal side 1 GBA1
endoplasmic reticulum 1 GBA1
extracellular space 5 A2M, F2, GH1, IGHE, NGF
lysosomal lumen 3 GAA, GBA1, SDC1
perinuclear region of cytoplasm 1 PDLIM4
adherens junction 1 PDLIM4
intercalated disc 1 DES
mitochondrion 2 CAT, COQ10A
protein-containing complex 2 CAT, SDC1
intracellular membrane-bounded organelle 4 ATP2B1, CAT, GAA, HPGDS
postsynaptic density 1 DTNB
Single-pass type I membrane protein 2 IGHE, SDC1
Secreted 7 A2M, CYB5D2, F2, GAA, GH1, NGF, SDC1
extracellular region 8 A2M, CAT, CYB5D2, F2, GAA, GH1, IGHE, NGF
Single-pass membrane protein 1 LRBA
mitochondrial matrix 1 CAT
transcription regulator complex 1 RBL2
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
external side of plasma membrane 1 SDC1
dendritic spine 1 PDLIM4
Z disc 2 DES, PDLIM4
nucleolus 1 RBL2
cell-cell junction 1 DES
postsynaptic membrane 1 PDLIM4
Cell membrane, sarcolemma 1 DES
Cell projection, lamellipodium 1 PDLIM4
Cytoplasm, perinuclear region 1 PDLIM4
Mitochondrion inner membrane 1 COQ10A
Matrix side 1 COQ10A
Cytoplasm, cytoskeleton 1 PDLIM4
focal adhesion 1 CAT
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Cell projection, dendritic spine 1 PDLIM4
collagen-containing extracellular matrix 2 A2M, F2
fascia adherens 1 DES
intermediate filament 1 DES
lateral plasma membrane 1 ATP2B1
chromatin 1 RBL2
IgE immunoglobulin complex 1 IGHE
cell projection 1 ATP2B1
Chromosome 1 RBL2
cytoskeleton 1 PDLIM4
blood microparticle 2 A2M, F2
Basolateral cell membrane 1 ATP2B1
[Isoform 2]: Cell membrane 1 IGHE
nuclear envelope 1 DES
Recycling endosome membrane 1 PDLIM4
Nucleus envelope 1 DES
Endomembrane system 2 CYB5D2, PDLIM4
endosome lumen 2 GH1, NGF
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
filamentous actin 1 PDLIM4
Cell projection, dendrite 1 DTNB
tertiary granule membrane 1 GAA
Presynaptic cell membrane 1 ATP2B1
intermediate filament cytoskeleton 1 DES
Cytoplasm, myofibril, sarcomere, Z line 1 DES
stress fiber 1 PDLIM4
basal plasma membrane 1 DTNB
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
Golgi lumen 3 F2, NGF, SDC1
endoplasmic reticulum lumen 1 F2
platelet alpha granule lumen 1 A2M
azurophil granule membrane 1 GAA
Secreted, extracellular exosome 1 SDC1
immunological synapse 1 ATP2B1
cell tip 1 DES
[Isoform 2]: Cytoplasm 1 PDLIM4
Synapse, synaptosome 1 PDLIM4
Basal cell membrane 1 DTNB
ficolin-1-rich granule membrane 1 GAA
[Isoform 1]: Cytoplasm, cytoskeleton 1 PDLIM4
inhibitory synapse 1 DTNB
[Isoform 3]: Cell membrane 1 IGHE
growth hormone receptor complex 1 GH1
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE
cardiac myofibril 1 DES
catalase complex 1 CAT
autolysosome lumen 1 GAA
photoreceptor ribbon synapse 1 ATP2B1
early endosome lumen 1 PDLIM4
recycling endosome lumen 1 PDLIM4


文献列表

  • Sarah Villringer, Josef Madl, Taras Sych, Christina Manner, Anne Imberty, Winfried Römer. Lectin-mediated protocell crosslinking to mimic cell-cell junctions and adhesion. Scientific reports. 2018 01; 8(1):1932. doi: 10.1038/s41598-018-20230-6. [PMID: 29386533]
  • NULL. Anti-diabetic Activity. Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques. 2016; 71(?):139-43. doi: NULL. [PMID: 26939280]
  • Hodaya V Solomon, Orly Tabachnikov, Shifra Lansky, Rachel Salama, Hadar Feinberg, Yuval Shoham, Gil Shoham. Structure-function relationships in Gan42B, an intracellular GH42 β-galactosidase from Geobacillus stearothermophilus. Acta crystallographica. Section D, Biological crystallography. 2015 Dec; 71(Pt 12):2433-48. doi: 10.1107/s1399004715018672. [PMID: 26627651]
  • Subhash R Rauthu, Tze Chieh Shiao, Sabine André, Michelle C Miller, Élodie Madej, Kevin H Mayo, Hans-Joachim Gabius, René Roy. Defining the potential of aglycone modifications for affinity/selectivity enhancement against medically relevant lectins: synthesis, activity screening, and HSQC-based NMR analysis. Chembiochem : a European journal of chemical biology. 2015 Jan; 16(1):126-39. doi: 10.1002/cbic.201402474. [PMID: 25407851]
  • Steven M Jones, Tammy T Dang, Robert Martinuzzi. Use of quorum sensing antagonists to deter the formation of crystalline Proteus mirabilis biofilms. International journal of antimicrobial agents. 2009 Oct; 34(4):360-4. doi: 10.1016/j.ijantimicag.2009.06.011. [PMID: 19619987]
  • Osamu Yamato, Asogi Kobayashi, Hiroyuki Satoh, Daiji Endoh, Toru Shoda, Yukiko Masuoka, Ayano Hatakeyama, Eun-Og Jo, Tomoya Asano, Madoka Yonemura, Masahiro Yamasaki, Yoshimitsu Maede. Comparison of polymerase chain reaction-restriction fragment length polymorphism assay and enzyme assay for diagnosis of G(M1)-gangliosidosis in Shiba dogs. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 2004 Jul; 16(4):299-304. doi: 10.1177/104063870401600407. [PMID: 15305740]
  • Xin-Liang Li, Lars G Ljungdahl, Eduardo A Ximenes, Huizhong Chen, Carlos R Felix, Michael A Cotta, Bruce S Dien. Properties of a recombinant beta-glucosidase from polycentric anaerobic fungus Orpinomyces PC-2 and its application for cellulose hydrolysis. Applied biochemistry and biotechnology. 2004; 113-116(?):233-50. doi: 10.1385/abab:113:1-3:233. [PMID: 15054209]
  • J Zouhar, J Vévodová, J Marek, J Damborský, X D Su, B Brzobohatý. Insights into the functional architecture of the catalytic center of a maize beta-glucosidase Zm-p60.1. Plant physiology. 2001 Nov; 127(3):973-85. doi: ". [PMID: 11706179]
  • W Hakamata, T Nishio, T Oku. Hydrolytic activity of alpha-galactosidases against deoxy derivatives of p-nitrophenyl alpha-D-galactopyranoside. Carbohydrate research. 2000 Feb; 324(2):107-15. doi: 10.1016/s0008-6215(99)00281-5. [PMID: 10702877]
  • K D Janda, L C Lo, C H Lo, M M Sim, R Wang, C H Wong, R A Lerner. Chemical selection for catalysis in combinatorial antibody libraries. Science (New York, N.Y.). 1997 Feb; 275(5302):945-8. doi: 10.1126/science.275.5302.945. [PMID: 9020070]
  • L Yang, T Akao, K Kobashi, M Hattori. A sennoside-hydrolyzing beta-glucosidase from Bifidobacterium sp. strain SEN is inducible. Biological & pharmaceutical bulletin. 1996 May; 19(5):701-4. doi: 10.1248/bpb.19.701. [PMID: 8741578]
  • L Yang, T Akao, K Kobashi, M Hattori. Purification and characterization of a novel sennoside-hydrolyzing beta-glucosidase from Bifidobacterium sp. strain SEN, a human intestinal anaerobe. Biological & pharmaceutical bulletin. 1996 May; 19(5):705-9. doi: 10.1248/bpb.19.705. [PMID: 8741579]
  • H Frøkiaer, P Møller, H Sørensen, S Sørensen. High-performance capillary electrophoresis for characterization of hapten-protein conjugates used for production of antibodies against soyasaponin I. Journal of chromatography. A. 1994 Oct; 680(2):437-45. doi: 10.1016/0021-9673(94)85141-7. [PMID: 7981825]
  • P Corbeau, M Haran, H Binz, C Devaux. Jacalin, a lectin with anti-HIV-1 properties, and HIV-1 gp120 envelope protein interact with distinct regions of the CD4 molecule. Molecular immunology. 1994 Jun; 31(8):569-75. doi: 10.1016/0161-5890(94)90164-3. [PMID: 8196669]
  • W Brabetz, W Liebl, K H Schleifer. Lactose permease of Escherichia coli catalyzes active beta-galactoside transport in a gram-positive bacterium. Journal of bacteriology. 1993 Nov; 175(22):7488-91. doi: 10.1128/jb.175.22.7488-7491.1993. [PMID: 8226697]