1-Octacosanol (BioDeep_00000000529)

 

Secondary id: BioDeep_00000859789

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


OCTACOSANOL (CONSTITUENT OF SAW PALMETTO) [DSC]

化学式: C28H58O (410.4487)
中文名称: 二十八烷醇, 1-十八烷醇
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 73.61%

分子结构信息

SMILES: C(CCCCCCCCCCCCCO)CCCCCCCCCCCCCC
InChI: InChI=1S/C28H58O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-27-28-29/h29H,2-28H2,1H3

描述信息

1-octacosanol is a white crystalline powder. (NTP, 1992)
Octacosan-1-ol is an ultra-long-chain primary fatty alcohol that is octacosane in which a hydrogen attached to one of the terminal carbons is replaced by a hydroxy group. It has a role as a plant metabolite. It is a fatty alcohol 28:0 and an ultra-long-chain primary fatty alcohol. It derives from a hydride of an octacosane.
1-octacosanol is a straight-chain aliphatic 28-carbon primary fatty alcohol that is used as a nutritional supplement. This high–molecular-weight organic compound is the main component of a natural product wax extracted from plants. 1-octacosanol is reported to possess cholesterol-lowering effects, antiaggregatory properties, cytoprotective use, and ergogenic properties. It has been studied as a potential therapeutic agent for the treatment of Parkinsons disease.
1-Octacosanol is a natural product found in Ophiopogon intermedius, Prosopis glandulosa, and other organisms with data available.
See also: Saw Palmetto (part of).
1-Octacosanol (also known as n-octacosanol, octacosyl alcohol, cluytyl alcohol, montanyl alcohol) is a straight-chain aliphatic 28-carbon primary fatty alcohol that is common in the epicuticular waxes of plants, including the leaves of many species of Eucalyptus, of most forage and cereal grasses, of Acacia, Trifolium, Pisum and many other legume genera among many others, sometimes as the major wax constituent. Octacosanol also occurs in wheat germ. Octacosanol is insoluble in water but freely soluble in low molecular-weight alkanes and in chloroform (CHCl3). 1-Octacosanol is found in many foods, some of which are common beet, black elderberry, red beetroot, and opium poppy.
1-Octacosanol (also known as n-octacosanol, octacosyl alcohol, cluytyl alcohol, montanyl alcohol) is a straight-chain aliphatic 28-carbon primary fatty alcohol that is common in the epicuticular waxes of plants, including the leaves of many species of Eucalyptus, of most forage and cereal grasses, of Acacia, Trifolium, Pisum and many other legume genera among many others, sometimes as the major wax constituent. Octacosanol also occurs in wheat germ. Octacosanol is insoluble in water but freely soluble in low molecular-weight alkanes and in chloroform (CHCl3). 1-Octacosanol is found in apple.
An ultra-long-chain primary fatty alcohol that is octacosane in which a hydrogen attached to one of the terminal carbons is replaced by a hydroxy group.

同义名列表

27 个代谢物同义名

OCTACOSANOL (CONSTITUENT OF SAW PALMETTO) [DSC]; OCTACOSANOL (CONSTITUENT OF SAW PALMETTO); 1-octacosanol, aluminum (1:3) salt; 1-Octacosanol, >=99\\% (GC); OCTACOSANOL [WHO-DD]; OCTACOSANOL [MART.]; OCTACOSANOL (MART.); Octacosyl alcohol; OCTACOSANOL [MI]; OCTACOSANOL,95\\%; Montanyl alcohol; Octacosanol,(S); Cluytyl alcohol; UNII-81I2215OVK; Octacosan-1-ol; OCTACOSANOL-1; 1-Octacosanol; n-octacosanol; octacosanol; polycosanol; 81I2215OVK; Octanosol; octacosyl; FOH 28:0; O8N; Octacosan-1-ol; 1-Octacosanol



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

77 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 AKT1, FASN, MYBPC3, PCSK9, PRKAA2, PRX, SIRT1, SREBF1, TH, TLR4, XDH
Peripheral membrane protein 1 PRX
Endosome membrane 2 FFAR4, TLR4
Endoplasmic reticulum membrane 2 PON1, SREBF1
Nucleus 8 AKT1, GABPA, PPARA, PRKAA2, PRX, SIRT1, SREBF1, TH
cytosol 8 AKT1, FASN, MYBPC3, PRKAA2, SIRT1, SREBF1, TH, XDH
dendrite 2 PRKAA2, TH
nucleoplasm 6 AKT1, GABPA, PPARA, PRKAA2, SIRT1, SREBF1
Cell membrane 6 AKT1, CACNA1H, FFAR4, PRX, TLR4, TNF
Cytoplasmic side 1 PRX
lamellipodium 1 AKT1
Cell projection, axon 1 TH
Multi-pass membrane protein 3 CACNA1H, FFAR4, SREBF1
Golgi apparatus membrane 1 SREBF1
cell cortex 1 AKT1
cell junction 1 PRX
cell surface 4 ADIPOQ, PCSK9, TLR4, TNF
glutamatergic synapse 1 AKT1
Golgi apparatus 3 FASN, PCSK9, PRKAA2
Golgi membrane 2 INS, SREBF1
lysosomal membrane 2 FFAR4, PCSK9
neuronal cell body 2 PRKAA2, TNF
postsynapse 1 AKT1
smooth endoplasmic reticulum 1 TH
synaptic vesicle 1 TH
Lysosome 1 PCSK9
endosome 1 PCSK9
plasma membrane 8 AKT1, CACNA1H, FASN, FFAR4, PCSK9, PRX, TLR4, TNF
terminal bouton 1 TH
Membrane 5 AKT1, CACNA1H, FASN, PRKAA2, TLR4
axon 2 PRKAA2, TH
extracellular exosome 2 FASN, PON1
Lysosome membrane 1 FFAR4
endoplasmic reticulum 3 ADIPOQ, PCSK9, SREBF1
extracellular space 7 ADIPOQ, IL6, INS, PCSK9, PON1, TNF, XDH
perinuclear region of cytoplasm 3 PCSK9, TH, TLR4
mitochondrion 2 SIRT1, TH
protein-containing complex 2 AKT1, SREBF1
chromatin silencing complex 1 SIRT1
Single-pass type I membrane protein 1 TLR4
Secreted 4 ADIPOQ, IL6, INS, PCSK9
extracellular region 6 ADIPOQ, IL6, INS, PCSK9, PON1, TNF
cytoplasmic side of plasma membrane 1 TH
anchoring junction 1 PRX
ciliary membrane 1 FFAR4
external side of plasma membrane 2 TLR4, TNF
high-density lipoprotein particle 1 PON1
perikaryon 1 TH
cytoplasmic vesicle 1 TH
microtubule cytoskeleton 1 AKT1
nucleolus 1 SIRT1
Melanosome membrane 1 TH
Early endosome 2 PCSK9, TLR4
cell-cell junction 1 AKT1
COPII-coated ER to Golgi transport vesicle 1 PCSK9
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
Cytoplasm, perinuclear region 1 TH
heterochromatin 1 SIRT1
Membrane raft 1 TNF
spindle 1 AKT1
Peroxisome 1 XDH
collagen trimer 1 ADIPOQ
sarcoplasmic reticulum 1 XDH
Nucleus, PML body 1 SIRT1
PML body 1 SIRT1
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
collagen-containing extracellular matrix 1 ADIPOQ
nuclear speck 1 PRKAA2
nuclear inner membrane 1 SIRT1
Cell projection, ruffle 1 TLR4
Late endosome 1 PCSK9
ruffle 1 TLR4
sarcomere 1 MYBPC3
receptor complex 1 TLR4
neuron projection 1 TH
ciliary basal body 1 AKT1
cilium 1 FFAR4
chromatin 4 GABPA, PPARA, SIRT1, SREBF1
phagocytic cup 2 TLR4, TNF
blood microparticle 1 PON1
[Isoform 2]: Cell membrane 1 FFAR4
myosin filament 1 MYBPC3
fibrillar center 1 SIRT1
nuclear envelope 2 SIRT1, SREBF1
endosome lumen 1 INS
Cytoplasmic vesicle membrane 1 SREBF1
Melanosome 1 FASN
cytoplasmic stress granule 1 PRKAA2
euchromatin 1 SIRT1
lipopolysaccharide receptor complex 1 TLR4
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 IL6, INS, PCSK9
voltage-gated calcium channel complex 1 CACNA1H
endocytic vesicle 1 FFAR4
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
ER to Golgi transport vesicle membrane 1 SREBF1
[Isoform 2]: Cytoplasm 1 PRX
A band 1 MYBPC3
endolysosome membrane 1 PCSK9
[Isoform 1]: Cell membrane 2 FFAR4, PRX
eNoSc complex 1 SIRT1
rDNA heterochromatin 1 SIRT1
nucleotide-activated protein kinase complex 1 PRKAA2
extrinsic component of external side of plasma membrane 1 PCSK9
Cell projection, cilium membrane 1 FFAR4
Cytoplasmic vesicle, COPII-coated vesicle membrane 1 SREBF1
spherical high-density lipoprotein particle 1 PON1
PCSK9-LDLR complex 1 PCSK9
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
cardiac myofibril 1 MYBPC3
interleukin-6 receptor complex 1 IL6
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle 1 TH
PCSK9-AnxA2 complex 1 PCSK9
[Sterol regulatory element-binding protein 1]: Endoplasmic reticulum membrane 1 SREBF1
[Processed sterol regulatory element-binding protein 1]: Nucleus 1 SREBF1
[Isoform SREBP-1aDelta]: Nucleus 1 SREBF1
[Isoform SREBP-1cDelta]: Nucleus 1 SREBF1
glycogen granule 1 FASN
striated muscle myosin thick filament 1 MYBPC3
C zone 1 MYBPC3
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
[SirtT1 75 kDa fragment]: Cytoplasm 1 SIRT1


文献列表

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