chlorpromazine (BioDeep_00000415967)
Main id: BioDeep_00000001933
代谢物信息卡片
chlorpromazine
化学式: C17H19ClN2S (318.0957404)
中文名称: 氯丙嗪
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: ClC1=CC=C2SC=3C=CC=CC3N(C2=C1)CCCN(C)C
InChI: InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3
描述信息
N - Nervous system > N05 - Psycholeptics > N05A - Antipsychotics > N05AA - Phenothiazines with aliphatic side-chain
D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents
D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists
C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent > C740 - Phenothiazine
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
C78272 - Agent Affecting Nervous System > C29710 - Antipsychotic Agent
D005765 - Gastrointestinal Agents > D000932 - Antiemetics
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
1 个代谢物同义名
数据库引用编号
23 个数据库交叉引用编号
- ChEBI: CHEBI:3647
- KEGG: C06906
- KEGGdrug: D00270
- PubChem: 2726
- DrugBank: DB00477
- ChEMBL: CHEMBL71
- MeSH: Chlorpromazine
- CAS: 146702-01-4
- CAS: 34468-21-8
- CAS: 50-53-3
- MoNA: MoNA038851
- MoNA: MoNA037622
- MoNA: MoNA036850
- MoNA: MoNA036849
- MoNA: MoNA036848
- MoNA: MoNA033399
- MoNA: MoNA033396
- MoNA: MoNA033392
- PubChem: 9123
- PDB-CCD: Z80
- 3DMET: B01058
- NIKKAJI: J2.794D
- RefMet: Chlorpromazine
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Gautam Kumar, Shobhna Kapoor. Targeting mycobacterial membranes and membrane proteins: Progress and limitations.
Bioorganic & medicinal chemistry.
2023 03; 81(?):117212. doi:
10.1016/j.bmc.2023.117212. [PMID: 36804747] - Jinxia Dai, Hui Lin, Yuning Pan, Yanmin Sun, Ye Wang, Jun-Qin Qiao, Hong-Zhen Lian, Chun-Xiang Xu. Determination of chlorpromazine and its metabolites in animal-derived foods using QuEChERS-based extraction, EMR-Lipid cleanup, and UHPLC-Q-Orbitrap MS analysis.
Food chemistry.
2023 Mar; 403(?):134298. doi:
10.1016/j.foodchem.2022.134298. [PMID: 36182851] - Lijuan Li, Xiaohu Liu, Yunxia Cui, Yang Chen, Huiwen Wu, Jing Wang, Xiaodi Gong, Xiaoyan Gao, Linlin Yang, Jian Li, Xiao Sun, Fei Mao, Yudong Wang. Novel chlorpromazine derivatives as anti-endometrial carcinoma agents with reduced extrapyramidal side effects.
Bioorganic chemistry.
2022 10; 127(?):106008. doi:
10.1016/j.bioorg.2022.106008. [PMID: 35868106] - Xuemei Liu, Tao Fan, Jinshuai Guan, Ai Luo, Yan Yu, Daohong Chen, Bing Mao, Hongli Jiang, Wei Liu. Dopamine relieves inflammatory responses through the D2 receptor after electroacupuncture at ST36 in a mouse model of chronic obstructive pulmonary disease.
Acupuncture in medicine : journal of the British Medical Acupuncture Society.
2022 Jul; ?(?):9645284221107684. doi:
10.1177/09645284221107684. [PMID: 35775581] - Iwona Karwaciak, Kaja Karaś, Anna Sałkowska, Joanna Pastwińska, Marcin Ratajewski. Chlorpromazine, a Clinically Approved Drug, Inhibits SARS-CoV-2 Nucleocapsid-Mediated Induction of IL-6 in Human Monocytes.
Molecules (Basel, Switzerland).
2022 Jun; 27(12):. doi:
10.3390/molecules27123651. [PMID: 35744777] - Katia Sayyed, Ibrahim Hdayed, Mohamad Tabcheh, Ziad Abdel-Razzak, Hoda El-Bitar. Antioxidant properties of the Lebanese plant Iris x germanica L. crude extracts and antagonism of chlorpromazine toxicity on Saccharomyces cerevisiae.
Drug and chemical toxicology.
2022 May; 45(3):1168-1179. doi:
10.1080/01480545.2020.1810261. [PMID: 32847432] - Chinedu Ifeanyi Atama, Excellence Chidera Nnaji, Ifeanyi Christian Ezeoyili, Faith Okwukwe Udeani, Chioma Juliet Onovo, Nelson Ike Ossai, Ifeanyi Oscar Aguzie, Christopher Didigwu Nwani. Neuromodulatory and oxidative stress evaluations in African catfish Clarias gariepinus exposed to antipsychotic drug chlorpromazine.
Drug and chemical toxicology.
2022 May; 45(3):1318-1324. doi:
10.1080/01480545.2020.1822391. [PMID: 32957809] - Cong Hu, Hong-Wei Li, Jia-Qun Ke, Xue-Chun Yu, Mei-Yu Zhao, Xin-Yue Shi, Lin-Jing Wu, Xi-Lan Tang, Yin-Hua Xiong. Metabolic profiling of lysophosphatidylcholines in chlorpromazine hydrochloride- and N-acetyl-p-amino-phenoltriptolide-induced liver injured rats based on ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry.
Human & experimental toxicology.
2022 Jan; 41(?):9603271221108320. doi:
10.1177/09603271221108320. [PMID: 35722787] - Yejin Ahn, Sung Hee Han, Min Guk Kim, Ki-Bae Hong, Woo Jung Kim, Hyung Joo Suh, Kyungae Jo. Anti-depressant effects of ethanol extract from Cannabis sativa (hemp) seed in chlorpromazine-induced Drosophila melanogaster depression model.
Pharmaceutical biology.
2021 Dec; 59(1):998-1007. doi:
10.1080/13880209.2021.1949356. [PMID: 34362287] - M T Yakubu, H T Fayemo. Anti-hyperprolactinemic activities of aqueous extract of Uvaria chamae (P. Beauv) roots and associated biochemical changes in chlorpromazine-induced hyperprolactinemic female Wistar rats.
Journal of ethnopharmacology.
2021 May; 271(?):113863. doi:
10.1016/j.jep.2021.113863. [PMID: 33485972] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Akbar Dorgalaleh, Ali Dabbagh, Shadi Tabibian, Mehran Bahraini, Hassan Rafieemehr. Persistent hiccups in a patient with mild congenital factor V deficiency and COVID-19; clinical and laboratory finding of a rare bleeding disorder.
International journal of laboratory hematology.
2021 04; 43(2):e87-e88. doi:
10.1111/ijlh.13385. [PMID: 33174336] - Hande Ikitimur, Betul Borku Uysal, Barıs Ikitimur, Sefika Umihanic, Jasmina Smajic, Rahima Jahic, Ayhan Olcay. Case Report: Two Cases of Persistent Hiccups Complicating COVID-19.
The American journal of tropical medicine and hygiene.
2021 Apr; 104(5):1713-1715. doi:
10.4269/ajtmh.21-0190. [PMID: 33793414] - Zhipeng Zhang, Jie Guo, Maojun Cheng, Weixin Zhou, Yang Wan, Rikang Wang, Yuanying Fang, Yi Jin, Jing Liu, Sai-Sai Xie. Design, synthesis, and biological evaluation of novel xanthone-alkylbenzylamine hybrids as multifunctional agents for the treatment of Alzheimer's disease.
European journal of medicinal chemistry.
2021 Mar; 213(?):113154. doi:
10.1016/j.ejmech.2021.113154. [PMID: 33476932] - Marion Plaze, David Attali, Matthieu Prot, Anne-Cécile Petit, Michael Blatzer, Fabien Vinckier, Laurine Levillayer, Jeanne Chiaravalli, Florent Perin-Dureau, Arnaud Cachia, Gérard Friedlander, Fabrice Chrétien, Etienne Simon-Loriere, Raphaël Gaillard. Inhibition of the replication of SARS-CoV-2 in human cells by the FDA-approved drug chlorpromazine.
International journal of antimicrobial agents.
2021 Mar; 57(3):106274. doi:
10.1016/j.ijantimicag.2020.106274. [PMID: 33387629] - Nicolas Hoertel, Marina Sánchez-Rico, Raphaël Vernet, Anne-Sophie Jannot, Antoine Neuraz, Carlos Blanco, Cédric Lemogne, Guillaume Airagnes, Nicolas Paris, Christel Daniel, Alexandre Gramfort, Guillaume Lemaitre, Mélodie Bernaux, Ali Bellamine, Nathanaël Beeker, Frédéric Limosin. Observational Study of Chlorpromazine in Hospitalized Patients with COVID-19.
Clinical drug investigation.
2021 Mar; 41(3):221-233. doi:
10.1007/s40261-021-01001-0. [PMID: 33559821] - Masaki Morishita, Maho Horita, Ayaka Higuchi, Maho Marui, Hidemasa Katsumi, Akira Yamamoto. Characterizing Different Probiotic-Derived Extracellular Vesicles as a Novel Adjuvant for Immunotherapy.
Molecular pharmaceutics.
2021 03; 18(3):1080-1092. doi:
10.1021/acs.molpharmaceut.0c01011. [PMID: 33554596] - Markus Blaess, Lars Kaiser, Oliver Sommerfeld, René Csuk, Hans-Peter Deigner. Drugs, Metabolites, and Lung Accumulating Small Lysosomotropic Molecules: Multiple Targeting Impedes SARS-CoV-2 Infection and Progress to COVID-19.
International journal of molecular sciences.
2021 Feb; 22(4):. doi:
10.3390/ijms22041797. [PMID: 33670304] - Adeleke Opeyemi, Oyewopo Adeoye, Akingbade Adebanji, Johnson Olawumi. CREM, PRM I and II gene expression in Wistar rats testes treated with antipsychotic drugs: Chlorpromazine, Rauwolfia vomitoria and co-administration of reserpine, zinc and ascorbic acid.
JBRA assisted reproduction.
2021 02; 25(1):97-103. doi:
10.5935/1518-0557.20200058. [PMID: 32960520] - Narjes Saheb Sharif-Askari, Fatemeh Saheb Sharif-Askari, Bushra Mdkhana, Saba Al Heialy, Elaref Ratemi, Malak Alghamdi, Salah Abusnana, Tarek Kashour, Qutayba Hamid, Rabih Halwani. Effect of common medications on the expression of SARS-CoV-2 entry receptors in liver tissue.
Archives of toxicology.
2020 12; 94(12):4037-4041. doi:
10.1007/s00204-020-02869-1. [PMID: 32808185] - Michał Otręba, Leon Kośmider, Anna Rzepecka-Stojko. Antiviral activity of chlorpromazine, fluphenazine, perphenazine, prochlorperazine, and thioridazine towards RNA-viruses. A review.
European journal of pharmacology.
2020 Nov; 887(?):173553. doi:
10.1016/j.ejphar.2020.173553. [PMID: 32949606] - NandhaKumar Sathyamoorthy, Pavan Kumar Chintamaneni, Santhivardhan Chinni. Plausible role of combination of Chlorpromazine hydrochloride and Teicoplanin against COVID-19.
Medical hypotheses.
2020 11; 144(?):110011. doi:
10.1016/j.mehy.2020.110011. [PMID: 32593831] - Ángel Ruiz de Pellón Santamaría. Psychosis Treatment During COVID-19 Pandemic and the Potential Role of Phenothiazines: A Call for Research Studies.
Journal of clinical psychopharmacology.
2020 Nov; 40(6):641-642. doi:
10.1097/jcp.0000000000001310. [PMID: 33136928] - Carli Weyers, Laura M K Dingle, Brendan S Wilhelmi, Adrienne L Edkins, Clinton G L Veale. Use of a non-hepatic cell line highlights limitations associated with cell-based assessment of metabolically induced toxicity.
Drug and chemical toxicology.
2020 Nov; 43(6):656-662. doi:
10.1080/01480545.2019.1585869. [PMID: 30880486] - Stuart Weston, Christopher M Coleman, Robert Haupt, James Logue, Krystal Matthews, Yize Li, Hanako M Reyes, Susan R Weiss, Matthew B Frieman. Broad Anti-coronavirus Activity of Food and Drug Administration-Approved Drugs against SARS-CoV-2 In Vitro and SARS-CoV In Vivo.
Journal of virology.
2020 10; 94(21):. doi:
10.1128/jvi.01218-20. [PMID: 32817221] - Emmanuel Stip. Psychiatry and COVID-19: The Role of Chlorpromazine.
Canadian journal of psychiatry. Revue canadienne de psychiatrie.
2020 10; 65(10):739-740. doi:
10.1177/0706743720934997. [PMID: 32536208] - Sai-Sai Xie, Jing Liu, Chunli Tang, Chengyun Pang, Qing Li, Yuelian Qin, Xiaojie Nong, Zhipeng Zhang, Jie Guo, Maojun Cheng, Weizhong Tang, Ningsheng Liang, Neng Jiang. Design, synthesis and biological evaluation of rasagiline-clorgyline hybrids as novel dual inhibitors of monoamine oxidase-B and amyloid-β aggregation against Alzheimer's disease.
European journal of medicinal chemistry.
2020 Sep; 202(?):112475. doi:
10.1016/j.ejmech.2020.112475. [PMID: 32652406] - Oleg O Glebov. Understanding SARS-CoV-2 endocytosis for COVID-19 drug repurposing.
The FEBS journal.
2020 09; 287(17):3664-3671. doi:
10.1111/febs.15369. [PMID: 32428379] - B Nobile, M Durand, P Courtet, P Van de Perre, N Nagot, J P Molès, E Olié. Could the antipsychotic chlorpromazine be a potential treatment for SARS-CoV-2?.
Schizophrenia research.
2020 09; 223(?):373-375. doi:
10.1016/j.schres.2020.07.015. [PMID: 32773341] - Saira Saeed Khan, Rahila Ikram, Sadaf Naeem, Humera Khatoon, Humera Anser, Bushra Sikander. Effect of M. chamomilla L. tea on chlorpromazine induced catalepsy: A neuroprotective study.
Pakistan journal of pharmaceutical sciences.
2020 Sep; 33(5):1945-1953. doi:
. [PMID: 33824100] - George Mihai Nitulescu, Horia Paunescu, Sterghios A Moschos, Dimitrios Petrakis, Georgiana Nitulescu, George Nicolae Daniel Ion, Demetrios A Spandidos, Taxiarchis Konstantinos Nikolouzakis, Nikolaos Drakoulis, Aristidis Tsatsakis. Comprehensive analysis of drugs to treat SARS‑CoV‑2 infection: Mechanistic insights into current COVID‑19 therapies (Review).
International journal of molecular medicine.
2020 Aug; 46(2):467-488. doi:
10.3892/ijmm.2020.4608. [PMID: 32468014] - Guang-Xin Miao, You-de Wang, Zhi-Wei Yan, Li-Ying Zhang. Synthesis, in vitro ADME profiling and in vivo pharmacological evaluation of novel glycogen phosphorylase inhibitors.
Bioorganic & medicinal chemistry letters.
2020 07; 30(14):127117. doi:
10.1016/j.bmcl.2020.127117. [PMID: 32527535] - M Plaze, D Attali, A-C Petit, M Blatzer, E Simon-Loriere, F Vinckier, A Cachia, F Chrétien, R Gaillard. Repurposing chlorpromazine to treat COVID-19: The reCoVery study.
L'Encephale.
2020 Jun; 46(3):169-172. doi:
10.1016/j.encep.2020.05.006. [PMID: 32425222] - M Plaze, D Attali, A-C Petit, M Blatzer, E Simon-Loriere, F Vinckier, A Cachia, F Chrétien, R Gaillard. [Repurposing of chlorpromazine in COVID-19 treatment: the reCoVery study].
L'Encephale.
2020 Jun; 46(3S):S35-S39. doi:
10.1016/j.encep.2020.04.010. [PMID: 32387014] - Richard Bouley, Naofumi Yui, Abby Terlouw, Pui W Cheung, Dennis Brown. Chlorpromazine Induces Basolateral Aquaporin-2 Accumulation via F-Actin Depolymerization and Blockade of Endocytosis in Renal Epithelial Cells.
Cells.
2020 04; 9(4):. doi:
10.3390/cells9041057. [PMID: 32340337] - Shi-Cheng Ling, Mei-Qin Zhuo, Dian-Guang Zhang, Heng-Yang Cui, Zhi Luo. Nano-Zn Increased Zn Accumulation and Triglyceride Content by Up-Regulating Lipogenesis in Freshwater Teleost, Yellow Catfish Pelteobagrus fulvidraco.
International journal of molecular sciences.
2020 Feb; 21(5):. doi:
10.3390/ijms21051615. [PMID: 32120818] - Ramona Figat, Anita Śliwińska, Anna Stochmal, Agata Soluch, Magdalena Sobczak, Anna Zgadzaj, Katarzyna Sykłowska-Baranek, Agnieszka Pietrosiuk. Antigenotoxic, Anti-photogenotoxic, and Antioxidant Properties of Polyscias filicifolia Shoots Cultivated In Vitro.
Molecules (Basel, Switzerland).
2020 Feb; 25(5):. doi:
10.3390/molecules25051090. [PMID: 32121158] - Paulina Trombik, Katarzyna Cieślik-Boczula. Influence of phenothiazine molecules on the interactions between positively charged poly-l-lysine and negatively charged DPPC/DPPG membranes.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2020 Feb; 227(?):117563. doi:
10.1016/j.saa.2019.117563. [PMID: 31689607] - Daniel Limones-Herrero, Fabrizio Palumbo, Victoria Vendrell-Criado, Inmaculada Andreu, Emilio Lence, Concepción González-Bello, Miguel A Miranda, M Consuelo Jiménez. Investigation of metabolite-protein interactions by transient absorption spectroscopy and in silico methods.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2020 Feb; 226(?):117652. doi:
10.1016/j.saa.2019.117652. [PMID: 31654902] - Predrag Kalaba, Marija Ilić, Nilima Y Aher, Vladimir Dragačević, Marcus Wieder, Martin Zehl, Judith Wackerlig, Stanislav Beyl, Simone B Sartori, Karl Ebner, Alexander Roller, Natalie Lukic, Tetyana Beryozkina, Eduardo Rene Perez Gonzalez, Philip Neill, Jawad Akbar Khan, Vasiliy Bakulev, Johann Jakob Leban, Steffen Hering, Christian Pifl, Nicolas Singewald, Jana Lubec, Ernst Urban, Harald H Sitte, Thierry Langer, Gert Lubec. Structure-Activity Relationships of Novel Thiazole-Based Modafinil Analogues Acting at Monoamine Transporters.
Journal of medicinal chemistry.
2020 01; 63(1):391-417. doi:
10.1021/acs.jmedchem.9b01938. [PMID: 31841637] - Anthony T Olofinnade, Tolulope M Onaolapo, Samad Oladimeji, Adetunji M Fatoki, Covenant I Balogun, Adejoke Y Onaolapo, Olakunle J Onaolapo. An Evaluation of the Effects of Pyridoxal Phosphate in Chlorpromazineinduced Parkinsonism using Mice.
Central nervous system agents in medicinal chemistry.
2020; 20(1):13-25. doi:
10.2174/1871524920666200120142508. [PMID: 31987026] - Yan-Jie Han, Zhi-Guang Ren, Xin-Xin Li, Ji-Liang Yan, Chun-Yan Ma, Dong-Dong Wu, Xin-Ying Ji. Advances and challenges in the prevention and treatment of COVID-19.
International journal of medical sciences.
2020; 17(12):1803-1810. doi:
10.7150/ijms.47836. [PMID: 32714083] - Neethu Sebastian, Wan-Chin Yu, Yu-Chung Hu, Deepak Balram, Yuan-Hsiang Yu. Sonochemical synthesis of iron-graphene oxide/honeycomb-like ZnO ternary nanohybrids for sensitive electrochemical detection of antipsychotic drug chlorpromazine.
Ultrasonics sonochemistry.
2019 Dec; 59(?):104696. doi:
10.1016/j.ultsonch.2019.104696. [PMID: 31430655] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Thapanan Jatuyosporn, Pasunee Laohawutthichai, Premruethai Supungul, Rogerio R Sotelo-Mundo, Adrian Ochoa-Leyva, Anchalee Tassanakajon, Kuakarun Krusong. Role of Clathrin Assembly Protein-2 Beta Subunit during White Spot Syndrome Virus Infection in Black Tiger Shrimp Penaeus monodon.
Scientific reports.
2019 09; 9(1):13489. doi:
10.1038/s41598-019-49852-0. [PMID: 31530841] - Kanae Nishimura, Noboru Okamura, Tetsutaro Kimachi, Jun Haginaka. Evaluation of molecularly imprinted polymers for chlorpromazine and bromopromazine prepared by multi-step swelling and polymerization method-The application for the determination of chlorpromazine and its metabolites in rat plasma by column-switching LC.
Journal of pharmaceutical and biomedical analysis.
2019 Sep; 174(?):248-255. doi:
10.1016/j.jpba.2019.05.063. [PMID: 31181487] - Mu-Yang Huang, Xiao-Ming Jiang, Yu-Lian Xu, Luo-Wei Yuan, Yu-Chi Chen, Guozhen Cui, Run-Yue Huang, Bo Liu, Yitao Wang, Xiuping Chen, Jin-Jian Lu. Platycodin D triggers the extracellular release of programed death Ligand-1 in lung cancer cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2019 Sep; 131(?):110537. doi:
10.1016/j.fct.2019.05.045. [PMID: 31150782] - Jeand Baloch, Muhammad Farhan Sohail, Hafiz Shaib Sarwar, Maria Hassan Kiani, Gul Majid Khan, Sarwat Jahan, Muhammad Rafay, Muhammad Tausif Chaudhry, Masoom Yasinzai, Gul Shahnaz. Self-Nanoemulsifying Drug Delivery System (SNEDDS) for Improved Oral Bioavailability of Chlorpromazine: In Vitro and In Vivo Evaluation.
Medicina (Kaunas, Lithuania).
2019 May; 55(5):. doi:
10.3390/medicina55050210. [PMID: 31137751] - B Lefrère, G Ulmann, M Chartier, J Patkaï, L Cynober, N Neveux. Malnutrition with hypoaminoacidemia in a 22-year-old pregnant patient masking a likely ornithine transcarbamylase deficiency.
Clinical nutrition ESPEN.
2019 04; 30(?):89-93. doi:
10.1016/j.clnesp.2019.02.001. [PMID: 30904234] - Tatiana Tozar, Viorel Nastasa, Alexandru Stoicu, Mariana Carmen Chifiriuc, Marcela Popa, Crina Kamerzan, Mihail Lucian Pascu. In vitro antimicrobial efficacy of laser exposed chlorpromazine against Gram-positive bacteria in planktonic and biofilm growth state.
Microbial pathogenesis.
2019 Apr; 129(?):250-256. doi:
10.1016/j.micpath.2019.02.012. [PMID: 30742947] - G D Alkimin, D Daniel, S Frankenbach, J Serôdio, A M V M Soares, C Barata, B Nunes. Evaluation of pharmaceutical toxic effects of non-standard endpoints on the macrophyte species Lemna minor and Lemna gibba.
The Science of the total environment.
2019 Mar; 657(?):926-937. doi:
10.1016/j.scitotenv.2018.12.002. [PMID: 30677958] - Luiz G M Beloti, Luis F C Miranda, Maria Eugênia C Queiroz. Butyl Methacrylate-Co-Ethylene Glycol Dimethacrylate Monolith for Online in-Tube SPME-UHPLC-MS/MS to Determine Chlopromazine, Clozapine, Quetiapine, Olanzapine, and Their Metabolites in Plasma Samples.
Molecules (Basel, Switzerland).
2019 Jan; 24(2):. doi:
10.3390/molecules24020310. [PMID: 30654481] - Rajalakshmi Rukmangathen, Indira Muzib Yallamalli, Prasanna Raju Yalavarthi. Biopharmaceutical Potential of Selegiline Loaded Chitosan Nanoparticles in the Management of Parkinson's Disease.
Current drug discovery technologies.
2019; 16(4):417-425. doi:
10.2174/1570163815666180418144019. [PMID: 29669501] - Magd Badaoui, Adam Kells, Carla Molteni, Callum J Dickson, Viktor Hornak, Edina Rosta. Calculating Kinetic Rates and Membrane Permeability from Biased Simulations.
The journal of physical chemistry. B.
2018 12; 122(49):11571-11578. doi:
10.1021/acs.jpcb.8b07442. [PMID: 30247032] - Jun-Ichi Kurita, Yuuka Hirao, Hirofumi Nakano, Yoshifumi Fukunishi, Yoshifumi Nishimura. Sertraline, chlorprothixene, and chlorpromazine characteristically interact with the REST-binding site of the corepressor mSin3, showing medulloblastoma cell growth inhibitory activities.
Scientific reports.
2018 09; 8(1):13763. doi:
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Journal of separation science.
2018 Sep; 41(18):3598-3606. doi:
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Journal of virological methods.
2018 09; 259(?):66-73. doi:
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Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine.
2018 08; 31(4):561-570. doi:
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Biochemical and biophysical research communications.
2018 06; 501(1):280-285. doi:
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Toxicology and applied pharmacology.
2018 06; 349(?):62-71. doi:
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Virology journal.
2018 05; 15(1):92. doi:
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European journal of medicinal chemistry.
2018 Apr; 150(?):946-957. doi:
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Therapeutic drug monitoring.
2018 04; 40(2):257-267. doi:
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Neuroscience.
2018 03; 373(?):72-81. doi:
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Zhonghua zhong liu za zhi [Chinese journal of oncology].
2018 Feb; 40(2):138-140. doi:
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Journal of bioenergetics and biomembranes.
2018 02; 50(1):59-69. doi:
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Nature communications.
2018 01; 9(1):130. doi:
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Molecular immunology.
2018 01; 93(?):47-54. doi:
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International journal of nanomedicine.
2018; 13(?):7549-7563. doi:
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Scientific reports.
2017 12; 7(1):16873. doi:
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Journal of separation science.
2017 Nov; 40(21):4222-4233. doi:
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Journal of chromatography. A.
2017 Oct; 1519(?):64-73. doi:
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Toxicology in vitro : an international journal published in association with BIBRA.
2017 Oct; 44(?):190-195. doi:
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Medicine.
2017 Sep; 96(39):e8191. doi:
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BMC complementary and alternative medicine.
2017 Aug; 17(1):389. doi:
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The Cochrane database of systematic reviews.
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Gut.
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 May; 1052(?):51-59. doi:
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Vojnosanitetski pregled.
2017 Apr; 73(4):312-7. doi:
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Neuropharmacology.
2017 04; 116(?):38-49. doi:
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PloS one.
2017; 12(8):e0182589. doi:
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International journal of nanomedicine.
2017; 12(?):2001-2019. doi:
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Acta cirurgica brasileira.
2016 Nov; 31(11):759-764. doi:
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Drug development and industrial pharmacy.
2016 Aug; 42(8):1258-66. doi:
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Biochimica et biophysica acta.
2016 Jul; 1858(7 Pt A):1499-506. doi:
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The Cochrane database of systematic reviews.
2016 Apr; 4(?):CD012122. doi:
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Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi.
2016 Apr; 120(2):452-6. doi:
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Acta poloniae pharmaceutica.
2016 Mar; 73(2):529-35. doi:
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European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2016 Jan; 81(?):27-35. doi:
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Oxidative medicine and cellular longevity.
2016; 2016(?):2394130. doi:
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Toxicology in vitro : an international journal published in association with BIBRA.
2015 Dec; 30(1 Pt B):364-72. doi:
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Journal of food science.
2015 Nov; 80(11):C2420-9. doi:
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Biochimica et biophysica acta.
2015 Nov; 1848(11 Pt A):2805-12. doi:
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The American journal of emergency medicine.
2015 Oct; 33(10):1541.e1-2. doi:
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Biomedical chromatography : BMC.
2015 Oct; 29(10):1535-40. doi:
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The American journal of the medical sciences.
2015 Sep; 350(3):212-7. doi:
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Environmental microbiology.
2015 Aug; 17(8):2805-23. doi:
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Journal of biomedical optics.
2015 May; 20(5):051002. doi:
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BMC complementary and alternative medicine.
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