octopamine (BioDeep_00000411061)
natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019
代谢物信息卡片
octopamine
化学式: C8H11NO2 (153.0789746)
中文名称: 奥克巴胺, 章鱼胺
谱图信息:
最多检出来源 Viridiplantae(plant) 1.7%
分子结构信息
SMILES: C1=CC(=CC=C1C(CN)O)O
InChI: InChI=1S/C8H11NO2/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4,8,10-11H,5,9H2
描述信息
C - Cardiovascular system > C01 - Cardiac therapy > C01C - Cardiac stimulants excl. cardiac glycosides > C01CA - Adrenergic and dopaminergic agents
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents
Octopamine, also known as beta,4-dihydroxyphenethylamine, is an endogenous biogenic amine that is closely related to norepinephrine, and has effects on the adrenergic and dopaminergic systems. Octopamine is found in lemon, sweet orange, and pepper (c. frutescens).
同义名列表
1 个代谢物同义名
数据库引用编号
32 个数据库交叉引用编号
- ChEBI: CHEBI:17134
- PubChem: 4581
- DrugBank: DB13251
- ChEMBL: CHEMBL53929
- MeSH: Octopamine
- foodb: FDB010583
- CAS: 104-14-3
- MoNA: Bruker_HCD_library001351
- MoNA: Bruker_HCD_library001352
- MoNA: MoNA038770
- MoNA: MoNA038550
- MoNA: MoNA037465
- MoNA: MoNA037156
- MoNA: MoNA036679
- MoNA: MoNA036678
- MoNA: MoNA036677
- MoNA: MoNA036014
- MoNA: MoNA036013
- MoNA: MoNA036012
- MoNA: MoNA032978
- MoNA: MoNA032974
- MoNA: MoNA032973
- MoNA: MoNA032077
- MoNA: MoNA032076
- MoNA: MoNA032075
- MoNA: EMBL-MCF_spec119246
- MoNA: EMBL-MCF_spec49019
- MoNA: VF-NPL-QTOF009149
- MoNA: VF-NPL-QTOF009148
- MoNA: VF-NPL-QTOF009147
- RefMet: Octopamine
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-226
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
- 558547 - Citrus deliciosa: 10.1002/PCA.771
- 85571 - Citrus reticulata: 10.1002/PCA.771
- 55188 - Citrus unshiu: 10.1002/PCA.771
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Shuhao Wang, Yang Li, Xin Lin, Xiangjin Fu, Haiyan Zhong, Kangzi Ren, Cheng Liu, Wen Yao. Rapid Screening of Phenolic Compounds with Anti-Enteritis Activity from Camellia oleifera Oil Using a Smurf Drosophila Model and Molecular Docking Methods.
Molecules (Basel, Switzerland).
2023 Dec; 29(1):. doi:
10.3390/molecules29010076. [PMID: 38202658] - Ping Cai, Yuanyuan Zhang, Mu Yang, Chenghao Zhang, Mingxia Li, Wei Xiao, Zhifeng Xu, Yongqiang Zhang. Target identification and acaricidal activity difference of amitraz and its metabolite DPMF in Tetranychus cinnabarinus (Boisduval).
Pest management science.
2023 Apr; ?(?):. doi:
10.1002/ps.7500. [PMID: 37036086] - Gang Xu, Yuan-Yuan Zhang, Gui-Xiang Gu, Guo-Qing Yang, Gong-Yin Ye. Molecular and Pharmacological Characterization of β-Adrenergic-like Octopamine Receptors in the Endoparasitoid Cotesia chilonis (Hymenoptera: Braconidae).
International journal of molecular sciences.
2022 Nov; 23(23):. doi:
10.3390/ijms232314513. [PMID: 36498840] - Yue Yang, Xingyu Ma, Long Zhang, Wenli Zhao, Xiaoguang Liu, Xiang Li, Mengfang Du, Shiheng An. Octopamine terminates sex pheromone biosynthesis by suppressing PBAN signal in moths.
Insect molecular biology.
2022 10; 31(5):647-658. doi:
10.1111/imb.12793. [PMID: 35652818] - Dandan Liu, Xinxin Zhang, Fang Chiqin, Innocent Nyamwasa, Yazhong Cao, Jiao Yin, Shuai Zhang, Honglin Feng, Kebin Li. Octopamine modulates insect mating and Oviposition.
Journal of chemical ecology.
2022 Aug; 48(7-8):628-640. doi:
10.1007/s10886-022-01366-2. [PMID: 35687218] - Pantea Kianmehr, Mohammad Ali Azarbayjani, Maghsoud Peeri, Parvin Farzanegi. The effects of aerobic exercise training with octopamine supplementation on cardiomyocyte apoptosis induced by deep-frying oil: The role of caspase and procaspase 3.
Clinical nutrition ESPEN.
2022 06; 49(?):529-535. doi:
10.1016/j.clnesp.2022.02.008. [PMID: 35623862] - Dahae Lee, Ji Hwan Lee, Byoung Ha Kim, Sanghyun Lee, Dong-Wook Kim, Ki Sung Kang. Phytochemical Combination (p-Synephrine, p-Octopamine Hydrochloride, and Hispidulin) for Improving Obesity in Obese Mice Induced by High-Fat Diet.
Nutrients.
2022 May; 14(10):. doi:
10.3390/nu14102164. [PMID: 35631305] - Sheraz Ahmad, Yu Chen, Jieyu Zhang, David Stanley, Qisheng Song, Linquan Ge. Octopamine signaling is involved in the female postmating state in Nilaparvata lugens Stål (Hemiptera: Delphacidae).
Archives of insect biochemistry and physiology.
2021 Aug; 107(4):e21825. doi:
10.1002/arch.21825. [PMID: 34164848] - Li-Sha Zheng, Xiao-Qiang Liu, Ge-Ge Liu, Qian-Qiao Huang, Jin-Jun Wang, Hong-Bo Jiang. Knockdown of a β-Adrenergic-Like Octopamine Receptor Affects Locomotion and Reproduction of Tribolium castaneum.
International journal of molecular sciences.
2021 Jul; 22(14):. doi:
10.3390/ijms22147252. [PMID: 34298876] - Yicong Jia, Shan Jin, Kunkun Hu, Lei Geng, Caihong Han, Ruxue Kang, Yuxin Pang, Erjun Ling, Eng King Tan, Yufeng Pan, Wei Liu. Gut microbiome modulates Drosophila aggression through octopamine signaling.
Nature communications.
2021 05; 12(1):2698. doi:
10.1038/s41467-021-23041-y. [PMID: 33976215] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Zhangwu Zhao, Xianguo Zhao, Tao He, Xiaoyu Wu, Pengfei Lv, Alan J Zhu, Juan Du. Epigenetic regulator Stuxnet modulates octopamine effect on sleep through a Stuxnet-Polycomb-Octβ2R cascade.
EMBO reports.
2021 02; 22(2):e47910. doi:
10.15252/embr.201947910. [PMID: 33410264] - Abisola Grace Ayanlowo, Zsófia Garádi, Imre Boldizsár, András Darcsi, Andrea Nagyné Nedves, Bence Varjas, Alexandra Simon, Ágnes Alberti, Eszter Riethmüller. UHPLC-DPPH method reveals antioxidant tyramine and octopamine derivatives in Celtis occidentalis.
Journal of pharmaceutical and biomedical analysis.
2020 Nov; 191(?):113612. doi:
10.1016/j.jpba.2020.113612. [PMID: 32980795] - Mohamed Ahmed Ibrahim Ahmed, Christoph Franz Adam Vogel. Hazardous effects of octopamine receptor agonists on altering metabolism-related genes and behavior of Drosophila melanogaster.
Chemosphere.
2020 Aug; 253(?):126629. doi:
10.1016/j.chemosphere.2020.126629. [PMID: 32283422] - Gang Xu, Xue-Fei Chang, Gui-Xiang Gu, Wen-Xi Jia, Lei Guo, Jia Huang, Gong-Yin Ye. Molecular and pharmacological characterization of a β-adrenergic-like octopamine receptor from the green rice leafhopper Nephotettix cincticeps.
Insect biochemistry and molecular biology.
2020 05; 120(?):103337. doi:
10.1016/j.ibmb.2020.103337. [PMID: 32109588] - Vanessa Corby-Harris, Megan E Deeter, Lucy Snyder, Charlotte Meador, Ashley C Welchert, Amelia Hoffman, Bethany T Obernesser. Octopamine mobilizes lipids from honey bee (Apis mellifera) hypopharyngeal glands.
The Journal of experimental biology.
2020 04; 223(Pt 8):. doi:
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Open biology.
2020 04; 10(4):190035. doi:
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Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Andy Hsien Wei Koh, Russ Chess-Williams, Anna Elizabeth Lohning. Differential mechanisms of action of the trace amines octopamine, synephrine and tyramine on the porcine coronary and mesenteric artery.
Scientific reports.
2019 07; 9(1):10925. doi:
10.1038/s41598-019-46627-5. [PMID: 31358768] - Sandra Arancibia, Matías Marambio, Jorge M Campusano, Angélica Fierro. Modeling of the Binding of Octopamine and Dopamine in Insect Monoamine Transporters Reveals Structural and Electrostatic Differences.
ACS chemical neuroscience.
2019 05; 10(5):2310-2317. doi:
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Fish & shellfish immunology.
2019 Jan; 84(?):532-540. doi:
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International journal of molecular sciences.
2018 Mar; 19(3):. doi:
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Scientific reports.
2018 02; 8(1):3215. doi:
10.1038/s41598-018-20711-8. [PMID: 29453438] - Ross E Beaumont, Philip Cordery, Lewis J James, Phillip Watson. Supplementation with a low-dose of octopamine does not influence endurance cycling performance in recreationally active men.
Journal of science and medicine in sport.
2017 Oct; 20(10):952-956. doi:
10.1016/j.jsams.2017.03.007. [PMID: 28389217] - Shun-Fan Wu, Xiao-Min Jv, Jian Li, Guang-Jian Xu, Xiao-Yi Cai, Cong-Fen Gao. Pharmacological characterisation and functional roles for egg-laying of a β-adrenergic-like octopamine receptor in the brown planthopper Nilaparvata lugens.
Insect biochemistry and molecular biology.
2017 08; 87(?):55-64. doi:
10.1016/j.ibmb.2017.06.008. [PMID: 28629966] - Rachel R Rix, G Christopher Cutler. Acute Exposure to Worst-Case Concentrations of Amitraz Does Not Affect Honey Bee Learning, Short-Term Memory, or Hemolymph Octopamine Levels.
Journal of economic entomology.
2017 02; 110(1):127-132. doi:
10.1093/jee/tow250. [PMID: 28028168] - Hui-Min Li, Hong-Bo Jiang, Shun-Hua Gui, Xiao-Qiang Liu, Hong Liu, Xue-Ping Lu, Guy Smagghe, Jin-Jun Wang. Characterization of a β-Adrenergic-Like Octopamine Receptor in the Oriental Fruit Fly, Bactrocera dorsalis (Hendel).
International journal of molecular sciences.
2016 Sep; 17(10):. doi:
10.3390/ijms17101577. [PMID: 27669213] - Poojan Pyakurel, Eve Privman Champaloux, B Jill Venton. Fast-Scan Cyclic Voltammetry (FSCV) Detection of Endogenous Octopamine in Drosophila melanogaster Ventral Nerve Cord.
ACS chemical neuroscience.
2016 08; 7(8):1112-9. doi:
10.1021/acschemneuro.6b00070. [PMID: 27326831] - Jun Tao, Yi-Cheng Ma, Zhong-Shan Yang, Cheng-Gang Zou, Ke-Qin Zhang. Octopamine connects nutrient cues to lipid metabolism upon nutrient deprivation.
Science advances.
2016 05; 2(5):e1501372. doi:
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Food & function.
2016 Mar; 7(3):1483-91. doi:
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2016 Feb; 186(2):169-79. doi:
10.1007/s00360-015-0953-1. [PMID: 26686231] - Monika Sobiech, Teresa Żołek, Piotr Luliński, Dorota Maciejewska. Separation of octopamine racemate on (R,S)-2-amino-1-phenylethanol imprinted polymer--Experimental and computational studies.
Talanta.
2016; 146(?):556-67. doi:
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Bioorganic & medicinal chemistry letters.
2015 Apr; 25(7):1476-8. doi:
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Journal of insect physiology.
2015 Apr; 75(?):39-46. doi:
10.1016/j.jinsphys.2015.03.004. [PMID: 25772095] - N Kirk Hillier, Rhys M B Kavanagh. Differential Octopaminergic Modulation of Olfactory Receptor Neuron Responses to Sex Pheromones in Heliothis virescens.
PloS one.
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Science (New York, N.Y.).
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The Journal of experimental biology.
2012 Aug; 215(Pt 15):2646-52. doi:
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Biomedical chromatography : BMC.
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The Biochemical journal.
2009 Oct; 424(1):39-45. doi:
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Neuroscience.
2009 Sep; 162(4):1120-33. doi:
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Lipids in health and disease.
2009 Aug; 8(?):32. doi:
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Chemical senses.
2009 Jun; 34(5):363-72. doi:
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General and comparative endocrinology.
2009 May; 162(1):18-26. doi:
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Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology.
2009 May; 30 Suppl 1(?):S55-9. doi:
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Journal of the International Society of Sports Nutrition.
2009 01; 6(?):4. doi:
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Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.
2008 Nov; 151(3):305-10. doi:
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Ying yong sheng tai xue bao = The journal of applied ecology.
2008 Nov; 19(11):2533-7. doi:
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Molecular pharmacology.
2008 Sep; 74(3):585-594. doi:
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The Journal of pharmacology and experimental therapeutics.
2008 May; 325(2):617-28. doi:
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Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology.
2008 May; 29 Suppl 1(?):S88-92. doi:
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Journal of insect physiology.
2007 Dec; 53(12):1293-9. doi:
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Journal of helminthology.
2007 Dec; 81(4):421-7. doi:
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Plant cell reports.
2007 Nov; 26(11):2009-15. doi:
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Analytical biochemistry.
2007 Oct; 369(2):187-91. doi:
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Analytical and bioanalytical chemistry.
2007 Sep; 389(1):197-205. doi:
10.1007/s00216-007-1409-6. [PMID: 17579842] - Federica Pellati, Stefania Benvenuti. Chromatographic and electrophoretic methods for the analysis of phenethylamine [corrected] alkaloids in Citrus aurantium.
Journal of chromatography. A.
2007 Aug; 1161(1-2):71-88. doi:
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The Plant journal : for cell and molecular biology.
2007 Aug; 51(3):390-405. doi:
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Journal of nematology.
2007 Jun; 39(2):145-52. doi:
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Journal of medicinal chemistry.
2007 May; 50(9):2078-88. doi:
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The Journal of pharmacology and experimental therapeutics.
2007 Apr; 321(1):116-27. doi:
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Journal of AOAC International.
2007 Jan; 90(1):68-81. doi:
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The Journal of experimental biology.
2006 Dec; 209(Pt 24):4858-68. doi:
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Metabolism: clinical and experimental.
2006 Oct; 55(10):1397-405. doi:
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Insect biochemistry and molecular biology.
2006 Oct; 36(10):759-68. doi:
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Plant biology (Stuttgart, Germany).
2006 Sep; 8(5):653-61. doi:
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2006 Sep; 1125(2):182-8. doi:
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Cephalalgia : an international journal of headache.
2006 Aug; 26(8):968-72. doi:
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Journal of insect physiology.
2006 Mar; 52(3):309-19. doi:
10.1016/j.jinsphys.2005.11.010. [PMID: 16406398] - Christine A Haller, Neal L Benowitz, Peyton Jacob. Hemodynamic effects of ephedra-free weight-loss supplements in humans.
The American journal of medicine.
2005 Sep; 118(9):998-1003. doi:
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BMC genomics.
2005 Aug; 6(?):106. doi:
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The Journal of comparative neurology.
2005 Aug; 488(3):233-54. doi:
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Archives of insect biochemistry and physiology.
2005 Jul; 59(3):161-71. doi:
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Insect biochemistry and molecular biology.
2005 May; 35(5):461-70. doi:
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Plant & cell physiology.
2005 Mar; 46(3):454-66. doi:
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