cefotaxime (BioDeep_00000408886)
Main id: BioDeep_00000006367
代谢物信息卡片
化学式: C16H17N5O7S2 (455.0569)
中文名称: 头孢噻肟酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@H]([C@H]2SC1)NC(=O)/C(=N\OC)/c1csc(N)n1
InChI: InChI=1S/C16H17N5O7S2/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26)/b20-9+
描述信息
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01D - Other beta-lactam antibacterials > J01DD - Third-generation cephalosporins
A cephalosporin compound having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups.
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic
同义名列表
数据库引用编号
23 个数据库交叉引用编号
- ChEBI: CHEBI:94427
- ChEBI: CHEBI:204928
- KEGG: C06885
- KEGGdrug: D07647
- PubChem: 5361298
- PubChem: 5742673
- DrugBank: DB00493
- ChEMBL: CHEMBL1730
- MeSH: Cefotaxime
- CAS: 1056874-43-1
- CAS: 63527-52-6
- CAS: 60846-21-1
- MoNA: WA001738
- MoNA: WA001737
- MoNA: WA001736
- MoNA: WA001735
- MoNA: WA001734
- MetaboLights: MTBLC204928
- PubChem: 9102
- PDB-CCD: CE3
- NIKKAJI: J18.743G
- RefMet: Cefotaxime
- KNApSAcK: 204928
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Didrik H Grevskott, Vera Radisic, Francisco Salvà-Serra, Edward R B Moore, Kristine S Akervold, Manish P Victor, Nachiket P Marathe. Emergence and dissemination of epidemic-causing OXA-244 carbapenemase-producing Escherichia coli ST38 through hospital sewage in Norway, 2020-2022.
The Journal of hospital infection.
2024 Jan; ?(?):. doi:
10.1016/j.jhin.2023.12.020
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Archives of microbiology.
2024 Jan; 206(2):67. doi:
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BMC plant biology.
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PloS one.
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Cellular and molecular biology (Noisy-le-Grand, France).
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2020 04; 24(8):4486-4494. doi:
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Infection and immunity.
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Anaesthesia, critical care & pain medicine.
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Microbial drug resistance (Larchmont, N.Y.).
2019 Sep; 25(7):1041-1049. doi:
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European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology.
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Antimicrobial agents and chemotherapy.
2019 06; 63(6):. doi:
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BMC infectious diseases.
2019 May; 19(1):386. doi:
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Veterinary microbiology.
2019 May; 232(?):58-64. doi:
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Antimicrobial resistance and infection control.
2019; 8(?):39. doi:
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Foodborne pathogens and disease.
2019 01; 16(1):42-53. doi:
10.1089/fpd.2018.2531
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Pharmaceutical biology.
2018 Dec; 56(1):201-208. doi:
10.1080/13880209.2018.1446030
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Meat science.
2018 Nov; 145(?):23-30. doi:
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Clinical pharmacokinetics.
2018 07; 57(7):867-875. doi:
10.1007/s40262-017-0602-9
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Cellular and molecular biology (Noisy-le-Grand, France).
2018 Apr; 64(5):122-126. doi:
10.14715/cmb/2018.64.5.21
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Microbial drug resistance (Larchmont, N.Y.).
2018 Apr; 24(3):260-268. doi:
10.1089/mdr.2016.0297
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Antimicrobial agents and chemotherapy.
2018 04; 62(4):. doi:
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Antimicrobial agents and chemotherapy.
2018 04; 62(4):. doi:
10.1128/aac.00637-17
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European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology.
2018 Mar; 37(3):485-493. doi:
10.1007/s10096-018-3194-x
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FEMS microbiology letters.
2018 03; 365(5):. doi:
10.1093/femsle/fny009
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The Pediatric infectious disease journal.
2018 02; 37(2):e43-e45. doi:
10.1097/inf.0000000000001734
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European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology.
2018 Jan; 37(1):69-75. doi:
10.1007/s10096-017-3102-9
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Foodborne pathogens and disease.
2017 12; 14(12):711-718. doi:
10.1089/fpd.2017.2310
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Proceedings of the National Academy of Sciences of the United States of America.
2017 11; 114(48):12773-12778. doi:
10.1073/pnas.1712999114
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Transfusion.
2017 11; 57(11):2571-2577. doi:
10.1111/trf.14196
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Journal of water and health.
2017 Oct; 15(5):788-798. doi:
10.2166/wh.2017.257
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Microbial drug resistance (Larchmont, N.Y.).
2017 Sep; 23(6):695-702. doi:
10.1089/mdr.2016.0205
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Microbial pathogenesis.
2017 Aug; 109(?):45-48. doi:
10.1016/j.micpath.2017.05.023
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European journal of drug metabolism and pharmacokinetics.
2017 Aug; 42(4):635-645. doi:
10.1007/s13318-016-0375-9
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mBio.
2017 07; 8(4):. doi:
10.1128/mbio.00777-17
. [PMID: 28720731] - Lütfiye Öksüz, Nezahat Gürler. [Serotype distribution and antibiotic resistance of Streptococcus pneumoniae strains isolated from the adult patients in a Turkish üniversity hospital].
Mikrobiyoloji bulteni.
2017 Jul; 51(3):195-208. doi:
10.5578/mb.48638
. [PMID: 28929957] - Gerardo Cortés-Cortés, Patricia Lozano-Zarain, Carmen Torres, Carla Andrea Alonso, Ana María Ríos-Torres, Miguel Castañeda, Liliana López-Pliego, Armando Navarro, Rosa Del Carmen Rocha-Gracia. Extended-spectrum β-lactamase-producing Escherichia coli isolated from healthy humans in Mexico, including subclone ST131-B2-O25:H4-H30-Rx.
Journal of global antimicrobial resistance.
2017 06; 9(?):130-134. doi:
10.1016/j.jgar.2017.02.014
. [PMID: 28552831] - John Benedict Readman, George Dickson, Nick G Coldham. Tetrahedral DNA Nanoparticle Vector for Intracellular Delivery of Targeted Peptide Nucleic Acid Antisense Agents to Restore Antibiotic Sensitivity in Cefotaxime-Resistant Escherichia coli.
Nucleic acid therapeutics.
2017 Jun; 27(3):176-181. doi:
10.1089/nat.2016.0644
. [PMID: 28080251] - David Creytens. A subset of fat-predominant angiomyolipomas label for MDM2: a potential diagnostic pitfall; comment on Asch-Kendrick et al. 2016.
Human pathology.
2017 06; 64(?):232-233. doi:
10.1016/j.humpath.2016.12.033
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Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology.
2017 Jun; 18(2):104-107. doi:
10.1016/j.ajg.2017.05.010
. [PMID: 28579346] - Rumyana Markovska, Temenuga Stoeva, Lyudmila Boyanova, Petya Stankova, Daniela Pencheva, Radka Kaneva, Vanyo Mitev, Ivan Mitov. Isolation of Escherichia coli ST131 producing KPC-2 in Bulgaria.
Infectious diseases (London, England).
2017 May; 49(5):429-431. doi:
10.1080/23744235.2016.1270464
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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi.
2017 Feb; 69(2):129-134. doi:
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. [PMID: 28239081] - Esther Ríos, María Carmen López, Iciar Rodríguez-Avial, Esther Culebras, Juan José Picazo. Detection of Escherichia coli ST131 clonal complex (ST705) and Klebsiella pneumoniae ST15 among faecal carriage of extended-spectrum β-lactamase- and carbapenemase-producing Enterobacteriaceae.
Journal of medical microbiology.
2017 Feb; 66(2):169-174. doi:
10.1099/jmm.0.000399
. [PMID: 27902381] - Tatsuya Nakayama, Nguyen Cong Ha, Phong Quoc Le, Ryuji Kawahara, Yuko Kumeda, Yoshinori Sumimura, Yoshimasa Yamamoto. Consumption of edible ice contaminated with Acinetobacter, Pseudomonas, and Stenotrophomonas is a risk factor for fecal colonization with extended-spectrum β-lactamase-producing Escherichia coli in Vietnam.
Journal of water and health.
2017 ; 15(5):813-822. doi:
10.2166/wh.2017.054
. [PMID: 29040083] - Charlotte Sahlberg Bang, Isak Demirel, Robert Kruse, Katarina Persson. Global gene expression profiling and antibiotic susceptibility after repeated exposure to the carbon monoxide-releasing molecule-2 (CORM-2) in multidrug-resistant ESBL-producing uropathogenic Escherichia coli.
PloS one.
2017; 12(6):e0178541. doi:
10.1371/journal.pone.0178541
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Bioorganic & medicinal chemistry letters.
2016 11; 26(22):5539-5544. doi:
10.1016/j.bmcl.2016.10.004
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Scientific reports.
2016 11; 6(?):36280. doi:
10.1038/srep36280
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Preventive veterinary medicine.
2016 Nov; 134(?):122-127. doi:
10.1016/j.prevetmed.2016.10.006
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Revista Argentina de microbiologia.
2016 Oct; 48(4):320-324. doi:
10.1016/j.ram.2016.08.002
. [PMID: 27919513] - Gui-Guang Cheng, Dan Li, Bo Hou, Xiao-Nian Li, Lu Liu, Ying-Ying Chen, Paul-Keilah Lunga, Afsar Khan, Ya-Ping Liu, Zhi-Li Zuo, Xiao-Dong Luo. Melokhanines A-J, Bioactive Monoterpenoid Indole Alkaloids with Diverse Skeletons from Melodinus khasianus.
Journal of natural products.
2016 09; 79(9):2158-66. doi:
10.1021/acs.jnatprod.6b00011
. [PMID: 27584856] - Tiphaine Legrand, Dominique Vodovar, Nicolas Tournier, Nihel Khoudour, Anne Hulin. Simultaneous Determination of Eight β-Lactam Antibiotics, Amoxicillin, Cefazolin, Cefepime, Cefotaxime, Ceftazidime, Cloxacillin, Oxacillin, and Piperacillin, in Human Plasma by Using Ultra-High-Performance Liquid Chromatography with Ultraviolet Detection.
Antimicrobial agents and chemotherapy.
2016 08; 60(8):4734-42. doi:
10.1128/aac.00176-16
. [PMID: 27216076] - Joost B Koedijk, Corinne G H Valk-Swinkels, Tom A Rijpstra, Daan J Touw, Paul G H Mulder, Peter H J van der Voort, Nils E van 't Veer, Nardo J M van der Meer. Pilot Study of the Pharmacokinetics of Cefotaxime in Critically Ill Patients with Acute Kidney Injury Treated with Continuous Renal Replacement Therapy.
Antimicrobial agents and chemotherapy.
2016 06; 60(6):3587-90. doi:
10.1128/aac.02888-15
. [PMID: 27021325] - Li Bai, Jiayong Zhao, Xin Gan, Juan Wang, Xiuli Zhang, Shenghui Cui, Shengli Xia, Yujie Hu, Shaofei Yan, Jiahui Wang, Fengqin Li, Séamus Fanning, Jin Xu. Emergence and Diversity of Salmonella enterica Serovar Indiana Isolates with Concurrent Resistance to Ciprofloxacin and Cefotaxime from Patients and Food-Producing Animals in China.
Antimicrobial agents and chemotherapy.
2016 06; 60(6):3365-71. doi:
10.1128/aac.02849-15
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European journal of gastroenterology & hepatology.
2016 Mar; 28(3):e10-8. doi:
10.1097/meg.0000000000000548
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Journal of labelled compounds & radiopharmaceuticals.
2016 Mar; 59(3):109-16. doi:
10.1002/jlcr.3374
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Plant signaling & behavior.
2016; 11(4):e1143998. doi:
10.1080/15592324.2016.1143998
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Veterinary microbiology.
2015 Dec; 181(3-4):298-302. doi:
10.1016/j.vetmic.2015.10.004
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Letters in applied microbiology.
2015 Nov; 61(5):429-36. doi:
10.1111/lam.12484
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Antimicrobial agents and chemotherapy.
2015 Sep; 59(9):5847-50. doi:
10.1128/aac.00332-15
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Chemico-biological interactions.
2015 May; 233(?):71-80. doi:
10.1016/j.cbi.2015.03.004
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Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology.
2015 Apr; 31(4):528-31. doi:
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Journal of pharmaceutical and biomedical analysis.
2015 Mar; 107(?):325-32. doi:
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