Cefotaxime (BioDeep_00000006367)

 

Secondary id: BioDeep_00000408886

human metabolite blood metabolite


代谢物信息卡片


(6R,7R)-3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

化学式: C16H17N5O7S2 (455.0569372)
中文名称: 头孢噻肟酸, 头孢噻肟
谱图信息: 最多检出来源 Homo sapiens(blood) 35%

分子结构信息

SMILES: CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@H]([C@H]2SC1)NC(=O)/C(=N\OC)/c1csc(N)n1
InChI: InChI=1S/C16H17N5O7S2/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26)/b20-9-/t10-,14-/m1/s1

描述信息

Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01D - Other beta-lactam antibacterials > J01DD - Third-generation cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic

同义名列表

36 个代谢物同义名

(6R,7R)-3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7R)-3-(Acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7R)-3-(Acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; (6R,7R)-3-Acetoxymethyl-7-{2-(2-amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7R,Z)-3-(Acetoxymethyl)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7R)-3-Acetoxymethyl-7-{2-(2-amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate; (6R,7R,Z)-3-(Acetoxymethyl)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate; Cefotaxim (sodium salt); HR-756 (sodium salt); Aventis pharma brand OF cefotaxime sodium; Fustery brand OF cefotaxime sodium; Liomont brand OF cefotaxime sodium; Aventis brand OF cefotaxime sodium; Hoechst brand OF cefotaxime sodium; Merck brand OF cefotaxime sodium; Viken brand OF cefotaxime sodium; Galen brand OF cefotaxime sodium; Pisa brand OF cefotaxime sodium; Sodium, cefotaxime; cefotaxime sodium; Cefotaxim hikma; Cefotaximum; Cephotaxime; Cephotaxim; Cefotaxima; cefotaxime; Cefotaxim; Kendrick; Benaxima; Klaforan; Claforan; Fotexina; Primafen; Cefradil; Taporin; Biosint; CTX



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Didrik H Grevskott, Vera Radisic, Francisco Salvà-Serra, Edward R B Moore, Kristine S Akervold, Manish P Victor, Nachiket P Marathe. Emergence and dissemination of epidemic-causing OXA-244 carbapenemase-producing Escherichia coli ST38 through hospital sewage in Norway, 2020-2022. The Journal of hospital infection. 2024 Jan; ?(?):. doi: 10.1016/j.jhin.2023.12.020. [PMID: 38286237]
  • Chunxiu Lu, Liang Jin, Huifen Zhou, Jiehong Yang, Haitong Wan. Chlorogenic acid inhibits macrophage PANoptosis induced by cefotaxime-resistant Escherichia coli. Archives of microbiology. 2024 Jan; 206(2):67. doi: 10.1007/s00203-023-03777-5. [PMID: 38236396]
  • Yuling Tai, Jie Zhang, Youhui Chen, Yi Yuan, Honggang Wang, Luyao Yu, Shuangshuang Li, Lu Yang, Yifan Jin. Establishment and validation of a callus tissue transformation system for German chamomile (Matricaria chamomilla L.). BMC plant biology. 2023 Dec; 23(1):659. doi: 10.1186/s12870-023-04680-3. [PMID: 38124039]
  • Sylvia Sinelius, Jullietta Lady, Michellina Yunardy, Enty Tjoa, Agustina D R Nurcahyanti. Antibacterial activity of Lagerstreomia speciosa and its active compound, corosolic acid, enhances cefotaxime inhibitory activity against Staphylococcus aureus. Journal of applied microbiology. 2023 Aug; 134(8):. doi: 10.1093/jambio/lxad171. [PMID: 37541956]
  • Rael J Too, George C Gitao, Lilly C Bebora, Dixie F Mollenkopf, Samuel M Kariuki, Thomas E Wittum. Frequency and diversity of carbapenemase-producing Enterobacterales recovered from untreated wastewater impacted by selective media containing cefotaxime and meropenem in Ohio, USA. PloS one. 2023; 18(2):e0281909. doi: 10.1371/journal.pone.0281909. [PMID: 36812188]
  • Pauline Brepoels, Kenny Appermans, Camilo Andres Pérez-Romero, Bram Lories, Kathleen Marchal, Hans P Steenackers. Antibiotic Cycling Affects Resistance Evolution Independently of Collateral Sensitivity. Molecular biology and evolution. 2022 12; 39(12):. doi: 10.1093/molbev/msac257. [PMID: 36480297]
  • Muriel Masi, Julia Vergalli, Ishan Ghai, Andrea Barba-Bon, Thérèse Schembri, Werner M Nau, Daniel Lafitte, Mathias Winterhalter, Jean-Marie Pagès. Cephalosporin translocation across enterobacterial OmpF and OmpC channels, a filter across the outer membrane. Communications biology. 2022 10; 5(1):1059. doi: 10.1038/s42003-022-04035-y. [PMID: 36198902]
  • Kelei Zhao, Jing Li, Xiting Yang, Qianglin Zeng, Wei Liu, Yi Wu, Hui Zhou, Balakrishnan Prithiviraj, Xinrong Wang, Xikun Zhou, Yiwen Chu. Subinhibitory Cefotaxime and Levofloxacin Concentrations Contribute to Selection of Pseudomonas aeruginosa in Coculture with Staphylococcus aureus. Applied and environmental microbiology. 2022 06; 88(12):e0059222. doi: 10.1128/aem.00592-22. [PMID: 35638844]
  • Stan J F Hartman, Parth J Upadhyay, Ron A A Mathôt, Michiel van der Flier, Michiel F Schreuder, Roger J Brüggemann, Catherijne A Knibbe, Saskia N de Wildt. Population pharmacokinetics of intravenous cefotaxime indicates that higher doses are required for critically ill children. The Journal of antimicrobial chemotherapy. 2022 05; 77(6):1725-1732. doi: 10.1093/jac/dkac095. [PMID: 35383374]
  • Katarzyna Pauter, Małgorzata Szultka-Młyńska, Michał Szumski, Anna Król-Górniak, Paweł Pomastowski, Bogusław Buszewski. CE-DAD-MS/MS in the simultaneous determination and identification of selected antibiotic drugs and their metabolites in human urine samples. Electrophoresis. 2022 May; 43(9-10):978-989. doi: 10.1002/elps.202100190. [PMID: 34624141]
  • Luke T Richardson, Elizabeth K Neumann, Richard M Caprioli, Jeffrey M Spraggins, Touradj Solouki. Referenced Kendrick Mass Defect Annotation and Class-Based Filtering of Imaging MS Lipidomics Experiments. Analytical chemistry. 2022 04; 94(14):5504-5513. doi: 10.1021/acs.analchem.1c03715. [PMID: 35344335]
  • Charlotta Edlund, Anders Ternhag, Gunilla Skoog Ståhlgren, Petra Edquist, Åse Östholm Balkhed, Simon Athlin, Emeli Månsson, Maria Tempé, Jakob Bergström, Christian G Giske, Håkan Hanberger. The clinical and microbiological efficacy of temocillin versus cefotaxime in adults with febrile urinary tract infection, and its effects on the intestinal microbiota: a randomised multicentre clinical trial in Sweden. The Lancet. Infectious diseases. 2022 03; 22(3):390-400. doi: 10.1016/s1473-3099(21)00407-2. [PMID: 34756180]
  • Yarmarly C Guerra Valero, Tavey Dorofaeff, Jason A Roberts, Jeffrey Lipman, Mark G Coulthard, Louise Sparkes, Steven C Wallis, Suzanne L Parker. Development and validation of a UHPLC-MS/MS method to measure cefotaxime and metabolite desacetylcefotaxime in blood plasma: a pilot study suitable for capillary microsampling in critically ill children. Analytical and bioanalytical chemistry. 2021 Jul; 413(17):4483-4491. doi: 10.1007/s00216-021-03411-7. [PMID: 34041575]
  • Yancho Zarev, Pavlinka Popova, Kenn Foubert, Iliana Ionkova, Luc Pieters. Comparative LC-MS analysis of tropolone alkaloids from in vitro cultures and native sources of Gloriosa superba by Kendrick mass defect plots. Phytochemical analysis : PCA. 2021 Jul; 32(4):446-456. doi: 10.1002/pca.2992. [PMID: 32888246]
  • Kazuhiro Horiba, Michio Suzuki, Nobuyuki Tetsuka, Yoshihiko Kawano, Makoto Yamaguchi, Toshihiko Okumura, Takako Suzuki, Yuka Torii, Jun-Ichi Kawada, Makoto Morita, Shinya Hara, Tomoo Ogi, Yoshinori Ito. Pediatric sepsis cases diagnosed with group B streptococcal meningitis using next-generation sequencing: a report of two cases. BMC infectious diseases. 2021 Jun; 21(1):531. doi: 10.1186/s12879-021-06231-3. [PMID: 34090359]
  • Filippo Migliorini, Nicola Maffulli, Filippo Spiezia, Giuseppe Maria Peretti, Markus Tingart, Riccardo Giorgino. Potential of biomarkers during pharmacological therapy setting for postmenopausal osteoporosis: a systematic review. Journal of orthopaedic surgery and research. 2021 May; 16(1):351. doi: 10.1186/s13018-021-02497-0. [PMID: 34059108]
  • Akira Fukuda, Hiromi Nakamura, Kaoru Umeda, Kaori Yamamoto, Yuji Hirai, Masaru Usui, Jun Ogasawara. Seven-year surveillance of the prevalence of antimicrobial-resistant Escherichia coli isolates, with a focus on ST131 clones, among healthy people in Osaka, Japan. International journal of antimicrobial agents. 2021 Mar; 57(3):106298. doi: 10.1016/j.ijantimicag.2021.106298. [PMID: 33556490]
  • Benoît Pilmis, Olivier Jiang, Assaf Mizrahi, Jean-Claude Nguyen Van, Julie Lourtet-Hascoët, Olivier Voisin, Erwan Le Lorc'h, Sidonie Hubert, Elodie Ménage, Philippe Azria, Marie-Françoise Borie, Annabelle Mahé, Jean-Jacques Mourad, Eloïse Trabattoni, Olivier Ganansia, Jean-Ralph Zahar, Alban Le Monnier. No significant difference between ceftriaxone and cefotaxime in the emergence of antibiotic resistance in the gut microbiota of hospitalized patients: A pilot study. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2021 Mar; 104(?):617-623. doi: 10.1016/j.ijid.2021.01.025. [PMID: 33453395]
  • Kwang Won Seo, Young Ju Lee. The occurrence of CTX-M-producing E. coli in the broiler parent stock in Korea. Poultry science. 2021 Feb; 100(2):1008-1015. doi: 10.1016/j.psj.2020.09.005. [PMID: 33518059]
  • Calvina E L Estaleva, Tomas F Zimba, John Osei Sekyere, Usha Govinden, Hafizah Y Chenia, Gunnar S Simonsen, Bjørg Haldorsen, Sabiha Y Essack, Arnfinn Sundsfjord. High prevalence of multidrug resistant ESBL- and plasmid mediated AmpC-producing clinical isolates of Escherichia coli at Maputo Central Hospital, Mozambique. BMC infectious diseases. 2021 Jan; 21(1):16. doi: 10.1186/s12879-020-05696-y. [PMID: 33407206]
  • Yuanjun Wu, Yong Wu, Yong Yang, Baochan Chen, Jianqun Li, Ganping Guo, Fu Xiong. Case Report: First Case of Cefotaxime-Sulbactam-Induced Acute Intravascular Hemolysis in a Newborn With ABO Blood Type Incompatibility by the Mechanism of Non-Immunologic Protein Adsorption. Frontiers in immunology. 2021; 12(?):698541. doi: 10.3389/fimmu.2021.698541. [PMID: 35003054]
  • Rania M Hathout, Sherihan G Abdelhamid, Ghadir S El-Housseiny, Abdelkader A Metwally. Comparing cefotaxime and ceftriaxone in combating meningitis through nose-to-brain delivery using bio/chemoinformatics tools. Scientific reports. 2020 12; 10(1):21250. doi: 10.1038/s41598-020-78327-w. [PMID: 33277611]
  • Takahiro Motonaga, Takashi Furuta, Seigo Okada, Yuji Ohnishi, Yasuo Suzuki, Hiroki Yasudo, Shunji Hasegawa. Responses to Treatment According to the Cytokine Profiles of Pericardial Effusion in Two Children with Idiopathic Pericarditis. International heart journal. 2020 Nov; 61(6):1307-1310. doi: 10.1536/ihj.20-282. [PMID: 33191347]
  • Ambroise Le Pogam, Julien Lopinto, Adrien Pecriaux, Muriel Fartoukh, Juliette Guitard, Guillaume Voiriot. Strongyloides stercoralis disseminated infection in an HIV-infected adult. PLoS neglected tropical diseases. 2020 11; 14(11):e0008766. doi: 10.1371/journal.pntd.0008766. [PMID: 33151939]
  • Roberto B M Marano, Telma Fernandes, Célia M Manaia, Olga Nunes, Donald Morrison, Thomas U Berendonk, Norbert Kreuzinger, Tanel Tenson, Gianluca Corno, Despo Fatta-Kassinos, Christophe Merlin, Edward Topp, Edouard Jurkevitch, Leonie Henn, Andrew Scott, Stefanie Heß, Katarzyna Slipko, Mailis Laht, Veljo Kisand, Andrea Di Cesare, Popi Karaolia, Stella G Michael, Alice L Petre, Roberto Rosal, Amy Pruden, Virginia Riquelme, Ana Agüera, Belen Esteban, Aneta Luczkiewicz, Agnieszka Kalinowska, Anne Leonard, William H Gaze, Anthony A Adegoke, Thor A Stenstrom, Alfieri Pollice, Carlo Salerno, Carsten U Schwermer, Pawel Krzeminski, Hélène Guilloteau, Erica Donner, Barbara Drigo, Giovanni Libralato, Marco Guida, Helmut Bürgmann, Karin Beck, Hemda Garelick, Marta Tacão, Isabel Henriques, Isabel Martínez-Alcalá, Jose M Guillén-Navarro, Magdalena Popowska, Marta Piotrowska, Marcos Quintela-Baluja, Joshua T Bunce, Maria I Polo-López, Samira Nahim-Granados, Marie-Noëlle Pons, Milena Milakovic, Nikolina Udikovic-Kolic, Jérôme Ory, Traore Ousmane, Pilar Caballero, Antoni Oliver, Sara Rodriguez-Mozaz, Jose L Balcazar, Thomas Jäger, Thomas Schwartz, Ying Yang, Shichun Zou, Yunho Lee, Younggun Yoon, Bastian Herzog, Heidrun Mayrhofer, Om Prakash, Yogesh Nimonkar, Ester Heath, Anna Baraniak, Joana Abreu-Silva, Manika Choudhury, Leonardo P Munoz, Stela Krizanovic, Gianluca Brunetti, Ayella Maile-Moskowitz, Connor Brown, Eddie Cytryn. A global multinational survey of cefotaxime-resistant coliforms in urban wastewater treatment plants. Environment international. 2020 11; 144(?):106035. doi: 10.1016/j.envint.2020.106035. [PMID: 32835921]
  • María José Rodríguez-González, María Antonieta Jiménez-Pearson, Francisco Duarte, Tomás Poklepovich, Josefina Campos, Luis Nazario Araya-Sánchez, Manuel Chirino-Trejo, Elías Barquero-Calvo. Multidrug-Resistant CTX-M and CMY-2 Producing Escherichia coli Isolated from Healthy Household Dogs from the Great Metropolitan Area, Costa Rica. Microbial drug resistance (Larchmont, N.Y.). 2020 Nov; 26(11):1421-1428. doi: 10.1089/mdr.2020.0146. [PMID: 33085572]
  • Oleg N Oktyabrsky, Ksenia V Bezmaternykh, Galina V Smirnova, Alexey V Tyulenev. Effect of resveratrol and quercetin on the susceptibility of Escherichia coli to antibiotics. World journal of microbiology & biotechnology. 2020 Oct; 36(11):167. doi: 10.1007/s11274-020-02934-y. [PMID: 33025172]
  • Edurne Peña-Mendizabal, Sergi Morais, Ángel Maquieira. Neo-antigens for the serological diagnosis of IgE-mediated drug allergic reactions to antibiotics cephalosporin, carbapenem and monobactam. Scientific reports. 2020 09; 10(1):16037. doi: 10.1038/s41598-020-73109-w. [PMID: 32994501]
  • Claire Duployez, Rémi Le Guern, Claire Tinez, Anne-Laure Lejeune, Laurent Robriquet, Sophie Six, Caroline Loïez, Frédéric Wallet. Panton-Valentine Leukocidin-Secreting Staphylococcus aureus Pneumonia Complicating COVID-19. Emerging infectious diseases. 2020 Aug; 26(8):1939-1941. doi: 10.3201/eid2608.201413. [PMID: 32298228]
  • Dawood Al-Ajmi, Shafeeq Rahman, Sharmila Banu. Occurrence, virulence genes, and antimicrobial profiles of Escherichia coli O157 isolated from ruminants slaughtered in Al Ain, United Arab Emirates. BMC microbiology. 2020 07; 20(1):210. doi: 10.1186/s12866-020-01899-0. [PMID: 32677884]
  • Deepjyoti Paul, Debadatta Dhar Chanda, Atanu Chakravarty, Amitabha Bhattacharjee. An insight into analysis and elimination of plasmids encoding metallo-β-lactamases in Pseudomonas aeruginosa. Journal of global antimicrobial resistance. 2020 06; 21(?):3-7. doi: 10.1016/j.jgar.2019.09.002. [PMID: 31518725]
  • Fan Zhang. Efficacy of cefotaxime combined with gamma globulins on C-reactive protein and procalcitonin in neonatal sepsis. Cellular and molecular biology (Noisy-le-Grand, France). 2020 May; 66(2):172-176. doi: . [PMID: 32415945]
  • Lihong Li, Baozhong Ren, Jian Guo, Zhicang Zhang, Yuxing Cai, Jie Yin. Expression levels of blood platelet and C-reactive protein in patients with severely pneumonic and their predictive values for efficacy. Cellular and molecular biology (Noisy-le-Grand, France). 2020 May; 66(2):105-110. doi: 10.14715/cmb/2020.66.2.17. [PMID: 32415935]
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  • Y-B Xu, Y Ouyang, D Zhao. Curative effects of vancomycin and cefotaxime combined with gamma globulin respectively in neonatal septicemia and their influences on PCT, CRP and hs-CRP. European review for medical and pharmacological sciences. 2020 04; 24(8):4486-4494. doi: 10.26355/eurrev_202004_21031. [PMID: 32373986]
  • Anthony Ayodeji Adegoke, Chibuzor Ezinne Madu, Olayinka Ayobami Aiyegoro, Thor Axel Stenström, Anthony Ifeanyi Okoh. Antibiogram and beta-lactamase genes among cefotaxime resistant E. coli from wastewater treatment plant. Antimicrobial resistance and infection control. 2020 03; 9(1):46. doi: 10.1186/s13756-020-0702-4. [PMID: 32164766]
  • Dandan Li, Xiaoqing Wei, Taiguo Liu, Changzhong Liu, Wanquan Chen, Yuan Hu Xuan, Li Gao. Establishment of an Agrobacterium tumefaciens-mediated transformation system for Tilletia foetida. Journal of microbiological methods. 2020 02; 169(?):105810. doi: 10.1016/j.mimet.2019.105810. [PMID: 31857144]
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  • Albert Bernet Sánchez, Alba Bellés Bellés, Jesus Aramburu Arnuelos, Alfredo Jover Sanz, Eva Sesé Abizanda, Montserrat Vallverdú Vidal, Mercè García González. Entamoeba histolytica liver abscess case: could stool PCR avoid it?. Diagnosis (Berlin, Germany). 2020 01; 7(1):69-73. doi: 10.1515/dx-2019-0006. [PMID: 31256063]
  • Selam Tewelde, Subban Patharajan, Zenebe Teka, Desta Berhe Sbhatu. Assessing the Efficacy of Broad-Spectrum Antibiotics in Controlling Bacterial Contamination in the In Vitro Micropropagation of Ginger (Zingiber officinale Rosc). TheScientificWorldJournal. 2020; 2020(?):6431301. doi: 10.1155/2020/6431301. [PMID: 32581658]
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  • Harpa Karadottir, Maarten Coorens, Zhihai Liu, Yang Wang, Birgitta Agerberth, Christian G Giske, Peter Bergman. Klebsiella pneumoniae Expressing VIM-1 Metallo-β-Lactamase Is Resensitized to Cefotaxime via Thiol-Mediated Zinc Chelation. Infection and immunity. 2019 12; 88(1):. doi: 10.1128/iai.00756-19. [PMID: 31611270]
  • Hui Wei, Ali Movahedi, Chen Xu, Weibo Sun, Lingling Li, Dawei Li, Qiang Zhuge. Characterization, expression profiling, and functional analysis of a Populus trichocarpa defensin gene and its potential as an anti-Agrobacterium rooting medium additive. Scientific reports. 2019 10; 9(1):15359. doi: 10.1038/s41598-019-51762-0. [PMID: 31653915]
  • Adrien Bouglé, Olivier Dujardin, Victoria Lepère, Nora Ait Hamou, Charles Vidal, Guillaume Lebreton, Joe-Elie Salem, Najoua El-Helali, Grégoire Petijean, Julien Amour. PHARMECMO: Therapeutic drug monitoring and adequacy of current dosing regimens of antibiotics in patients on Extracorporeal Life Support. Anaesthesia, critical care & pain medicine. 2019 10; 38(5):493-497. doi: 10.1016/j.accpm.2019.02.015. [PMID: 30831307]
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