N-METHYLANILINE (BioDeep_00000405937)

Main id: BioDeep_00000003035

 

natural product


代谢物信息卡片


N-METHYLANILINE

化学式: C7H9N (107.0735)
中文名称: N-甲基苯胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C=1C=CC(=CC1)NC
InChI: InChI=1S/C7H9N/c1-8-7-5-3-2-4-6-7/h2-6,8H,1H3

描述信息

同义名列表

3 个代谢物同义名

N-METHYLANILINE; N-Methylaniline; N-methylaniline



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

14 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 CYP1A1, DIS3, EGFR, GFAP, HELB, HSF1, PMP2
Peripheral membrane protein 1 CYP1A1
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 4 CYP1A1, EGFR, PSEN1, RRBP1
Nucleus 8 DIS3, EGFR, HELB, HSF1, KDM5D, PMP2, PSEN1, TIPARP
cytosol 7 DIS3, GFAP, HELB, HSF1, MAT2A, MB, PMP2
dendrite 1 PSEN1
nuclear body 1 HELB
centrosome 2 HSF1, PSEN1
nucleoplasm 5 DIS3, HELB, HSF1, KDM5D, PSEN1
Cell membrane 5 CD244, EGFR, KCNH2, PROKR2, PSEN1
ruffle membrane 1 EGFR
Cell projection, axon 1 PSEN1
Cell projection, growth cone 1 PSEN1
Cytoplasmic granule 1 PSEN1
Early endosome membrane 2 EGFR, PSEN1
Multi-pass membrane protein 3 KCNH2, PROKR2, PSEN1
Golgi apparatus membrane 1 PSEN1
Synapse 2 NPS, PSEN1
cell cortex 1 PSEN1
cell junction 2 EGFR, PSEN1
cell surface 3 EGFR, KCNH2, PSEN1
ciliary rootlet 1 PSEN1
dendritic shaft 1 PSEN1
gamma-secretase complex 1 PSEN1
glutamatergic synapse 2 EGFR, PSEN1
Golgi apparatus 2 ATRN, PSEN1
Golgi membrane 2 EGFR, PSEN1
growth cone 1 PSEN1
lysosomal membrane 1 PSEN1
mitochondrial inner membrane 2 CYP1A1, PSEN1
neuromuscular junction 1 PSEN1
neuronal cell body 1 PSEN1
postsynapse 1 PSEN1
presynaptic membrane 1 PSEN1
sarcolemma 1 PSEN1
smooth endoplasmic reticulum 1 PSEN1
synaptic vesicle 1 PSEN1
endosome 1 EGFR
plasma membrane 7 ATRN, CD244, EGFR, KCNH2, ME2, PROKR2, PSEN1
Membrane 7 CD244, DIS3, EGFR, KCNH2, ME2, PSEN1, RRBP1
apical plasma membrane 1 EGFR
axon 1 PSEN1
basolateral plasma membrane 1 EGFR
extracellular exosome 3 ATRN, MB, PMP2
endoplasmic reticulum 2 PSEN1, RRBP1
extracellular space 2 ATRN, EGFR
perinuclear region of cytoplasm 3 EGFR, HSF1, KCNH2
mitochondrion 4 CYP1A1, HELB, ME2, PSEN1
protein-containing complex 2 EGFR, PSEN1
intracellular membrane-bounded organelle 2 CYP1A1, ME2
Microsome membrane 1 CYP1A1
Single-pass type I membrane protein 3 ATRN, CD244, EGFR
extracellular region 1 NPS
Single-pass membrane protein 2 ME2, RRBP1
astrocyte end-foot 1 GFAP
[Isoform 2]: Secreted 1 ATRN
Mitochondrion matrix 1 ME2
mitochondrial matrix 1 ME2
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 HSF1
nuclear membrane 2 EGFR, PSEN1
external side of plasma membrane 1 CD244
sarcoplasm 1 MB
Early endosome 1 PSEN1
Cytoplasm, perinuclear region 1 HSF1
Mitochondrion inner membrane 1 CYP1A1
heterochromatin 1 HSF1
Membrane raft 3 CD244, EGFR, PSEN1
focal adhesion 1 EGFR
intracellular vesicle 1 EGFR
PML body 1 HSF1
intermediate filament 1 GFAP
nuclear outer membrane 1 PSEN1
receptor complex 1 EGFR
Cell projection, neuron projection 1 PSEN1
neuron projection 1 PSEN1
chromatin 2 HSF1, KDM5D
cell projection 1 GFAP
Chromosome 1 HELB
Nucleus, nucleolus 1 DIS3
site of double-strand break 1 HELB
[Isoform 3]: Secreted 1 ATRN
Cytoplasm, cytoskeleton, spindle pole 1 HSF1
fibrillar center 1 KDM5D
Chromosome, centromere, kinetochore 1 HSF1
monoatomic ion channel complex 1 KCNH2
Nucleus, nucleoplasm 2 DIS3, HSF1
euchromatin 1 HSF1
cell body 1 GFAP
myelin sheath 1 PMP2
intermediate filament cytoskeleton 1 GFAP
basal plasma membrane 1 EGFR
cytoplasmic exosome (RNase complex) 1 DIS3
inward rectifier potassium channel complex 1 KCNH2
synaptic membrane 1 EGFR
voltage-gated potassium channel complex 1 KCNH2
kinetochore 2 HSF1, PSEN1
mitotic spindle pole 1 HSF1
azurophil granule membrane 1 PSEN1
Single-pass type III membrane protein 1 RRBP1
aggresome 1 PSEN1
clathrin-coated endocytic vesicle membrane 1 EGFR
ribonucleoprotein complex 1 HSF1
protein folding chaperone complex 1 HSF1
[Isoform 1]: Cell membrane 1 ATRN
Rough endoplasmic reticulum 1 PSEN1
exosome (RNase complex) 1 DIS3
cytoplasmic side of lysosomal membrane 1 GFAP
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
ribosome 1 RRBP1
Cytoplasm, sarcoplasm 1 MB
methionine adenosyltransferase complex 1 MAT2A
nuclear stress granule 1 HSF1
nuclear exosome (RNase complex) 1 DIS3


文献列表

  • Zhenzhen Zhang, Xueqian He, Xiaomin Zhang, Dehai Li, Guangwei Wu, Zhenzhen Liu, Chao Niu, Lanping Yang, Wenting Song, Zhanlin Li, Zhenhui Wang. Production of Multiple Talaroenamines from Penicillium malacosphaerulum via One-Pot/Two-Stage Precursor-Directed Biosynthesis. Journal of natural products. 2022 09; 85(9):2168-2176. doi: 10.1021/acs.jnatprod.2c00394. [PMID: 35993848]
  • Chatrawee Direksilp, Johannes M Scheiger, Nuttha Ariyasajjamongkol, Anuvat Sirivat. A highly selective and sensitive electrochemical sensor for dopamine based on a functionalized multi-walled carbon nanotube and poly(N-methylaniline) composite. Analytical methods : advancing methods and applications. 2022 01; 14(4):469-479. doi: 10.1039/d1ay01943k. [PMID: 35029250]
  • Huiwen Wang, Xiaoyong Zhao, Yu Huang, Jiancong Liao, Yaqin Liu, Yuanjiang Pan. Rapid quality control of medicine and food dual purpose plant polysaccharides by matrix assisted laser desorption/ionization mass spectrometry. The Analyst. 2020 Mar; 145(6):2168-2175. doi: 10.1039/c9an02440a. [PMID: 32104793]
  • Juejun Hu, Vladimir Tarasov, Anu Agarwal, Lionel Kimerling, Nathan Carlie, Laeticia Petit, Kathleen Richardson. Fabrication and testing of planar chalcogenide waveguide integrated microfluidic sensor. Optics express. 2007 Mar; 15(5):2307-14. doi: 10.1364/oe.15.002307. [PMID: 19532465]
  • Zakaria Rachid, Fouad Brahimi, Athanasia Katsoulas, Nicole Teoh, Bertrand J Jean-Claude. The combi-targeting concept: chemical dissection of the dual targeting properties of a series of "combi-triazenes". Journal of medicinal chemistry. 2003 Sep; 46(20):4313-21. doi: 10.1021/jm030142e. [PMID: 13678409]
  • S S Mirvish, M D Ramm, J P Sams, D M Babcook. Nitrosamine formation from amines applied to the skin of mice after and before exposure to nitrogen dioxide. Cancer research. 1988 Mar; 48(5):1095-9. doi: . [PMID: 3342392]
  • Y Shimojima, T Shirai, T Baba, H Hayashi. 1H-2-Benzopyran-1-one derivatives, microbial products with pharmacological activity. Conversion into orally active derivatives with antiinflammatory and antiulcer activities. Journal of medicinal chemistry. 1985 Jan; 28(1):3-9. doi: 10.1021/jm00379a002. [PMID: 3965711]
  • H M Pylypiw, J R Zubroff, P N Magee, G W Harrington. The metabolism of N-nitrosomethylaniline. Journal of cancer research and clinical oncology. 1984; 108(1):66-70. doi: 10.1007/bf00390975. [PMID: 6746719]
  • I C Calder, C C Funder, C R Green, K N Ham, J D Tange. Comparative nephrotoxicity of aspirin and phenacetin derivatives. British medical journal. 1971 Nov; 4(5786):518-21. doi: 10.1136/bmj.4.5786.518. [PMID: 5128205]
  • J WHITE, P MORI-CHAVEZ. Acute necrotizing renal papillitis experimentally produced in rats fed mono-N-methylaniline. Journal of the National Cancer Institute. 1952 Feb; 12(4):777-87. doi: NULL. [PMID: 14908543]