Glutaconic acid (BioDeep_00000405312)

Main id: BioDeep_00000629394

 


代谢物信息卡片


trans-Glutaconic acid

化学式: C5H6O4 (130.0266)
中文名称: 戊烯二酸, 谷氨酸, 反-戊烯二酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(=C\C(=O)O)/CC(=O)O
InChI: InChI=1S/C5H6O4/c6-4(7)2-1-3-5(8)9/h1-2H,3H2,(H,6,7)(H,8,9)

描述信息

A pentenedioic acid that is pent-2-ene substituted by carboxy groups at positions 1 and 5.

同义名列表

5 个代谢物同义名

Glutaconic acid; trans-Glutaconic acid; (E)-Glutaconate; Glutaconic acid; trans-Glutaconic acid



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ANXA5, BCL2, DBH, FH, HTT, PAM, S1PR1, SPHK1
Peripheral membrane protein 2 ANXA5, SPHK1
Endosome membrane 2 HTT, SPHK1
Endoplasmic reticulum membrane 1 BCL2
Nucleus 5 BCL2, FH, HTT, PAM, SPHK1
autophagosome 1 HTT
cytosol 7 ANXA5, BCL2, FH, HMGCL, HTT, PAM, SPHK1
dendrite 1 HTT
nucleoplasm 4 HTT, PAM, S1PR1, SPHK1
Cell membrane 5 HTT, S1PR1, SELP, SLC13A3, SPHK1
Cell projection, axon 1 PAM
Early endosome membrane 1 SPHK1
Multi-pass membrane protein 5 HTT, S1PR1, SLC13A3, SLC22A6, SLC22A9
Synapse 3 DBH, HTT, SPHK1
Golgi apparatus 1 HTT
mitochondrial inner membrane 1 ATP5ME
presynaptic membrane 1 HTT
sarcolemma 1 ANXA5
Presynapse 2 S1PR1, SPHK1
endosome 1 S1PR1
plasma membrane 7 HTT, PAM, S1PR1, SELP, SLC13A3, SLC22A6, SPHK1
Membrane 7 ANXA5, BCL2, DBH, PAM, SLC13A3, SLC22A6, SPHK1
axon 2 HTT, PAM
basolateral plasma membrane 3 SLC13A3, SLC22A6, SLC22A9
caveola 1 SLC22A6
extracellular exosome 6 ANXA5, FH, PAM, SELP, SLC13A3, SLC22A6
endoplasmic reticulum 3 BCL2, DBH, HTT
extracellular space 2 DBH, SELP
perinuclear region of cytoplasm 1 HTT
mitochondrion 5 ATP5ME, BCL2, FH, GCDH, HMGCL
protein-containing complex 4 BCL2, HMGCL, HTT, SLC22A6
intracellular membrane-bounded organelle 4 DBH, PAM, S1PR1, SPHK1
Single-pass type I membrane protein 1 SELP
Secreted 2 DBH, SELP
extracellular region 4 ANXA5, DBH, PAM, SELP
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 2 BCL2, PAM
mitochondrial outer membrane 1 BCL2
Mitochondrion matrix 2 GCDH, HMGCL
mitochondrial matrix 3 FH, GCDH, HMGCL
centriolar satellite 1 DBH
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 3 ANXA5, S1PR1, SELP
microtubule cytoskeleton 1 PAM
Early endosome 1 HTT
Membrane, clathrin-coated pit 1 SPHK1
clathrin-coated pit 1 SPHK1
Single-pass type II membrane protein 1 DBH
postsynaptic membrane 1 HTT
Membrane raft 2 HTT, S1PR1
pore complex 1 BCL2
Cell junction, focal adhesion 1 HTT
Cytoplasm, cytoskeleton 1 PAM
focal adhesion 2 ANXA5, HTT
Peroxisome 1 HMGCL
peroxisomal matrix 1 HMGCL
collagen-containing extracellular matrix 1 ANXA5
Late endosome 1 HTT
Cell projection, neuron projection 1 HTT
Zymogen granule membrane 1 ANXA5
neuron projection 1 HTT
Chromosome 1 FH
centriole 1 HTT
Basolateral cell membrane 2 SLC22A6, SLC22A9
site of double-strand break 1 FH
Endomembrane system 1 HTT
Cytoplasmic vesicle membrane 1 HTT
myelin sheath 1 BCL2
basal plasma membrane 1 SLC22A6
platelet dense granule membrane 1 SELP
secretory granule lumen 1 DBH
secretory granule membrane 2 DBH, PAM
endocytic vesicle 1 SPHK1
vesicle membrane 1 ANXA5
Basal cell membrane 1 SLC22A6
Cytoplasmic vesicle, secretory vesicle membrane 2 DBH, PAM
postsynaptic cytosol 1 HTT
platelet alpha granule membrane 1 SELP
presynaptic cytosol 1 HTT
proton-transporting ATP synthase complex 1 ATP5ME
proton-transporting ATP synthase complex, coupling factor F(o) 1 ATP5ME
Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen 1 DBH
chromaffin granule lumen 1 DBH
transport vesicle membrane 2 DBH, PAM
platelet dense granule lumen 1 SELP
inclusion body 1 HTT
[Isoform Mitochondrial]: Mitochondrion 1 FH
[Isoform Cytoplasmic]: Cytoplasm, cytosol 1 FH
endothelial microparticle 1 ANXA5
[Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen 1 DBH
Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane 1 DBH
chromaffin granule membrane 1 DBH
BAD-BCL-2 complex 1 BCL2
serotonergic synapse 1 HTT
[Huntingtin]: Cytoplasm 1 HTT
[Huntingtin, myristoylated N-terminal fragment]: Cytoplasmic vesicle, autophagosome 1 HTT


文献列表

  • Patrícia F Schuck, Estela N B Busanello, Anelise M Tonin, Carolina M Viegas, Gustavo C Ferreira. Neurotoxic effects of trans-glutaconic acid in rats. Oxidative medicine and cellular longevity. 2013; 2013(?):607610. doi: 10.1155/2013/607610. [PMID: 23606926]
  • E von Guggenberg, M Behe, T M Behr, M Saurer, T Seppi, C Decristoforo. 99mTc-labeling and in vitro and in vivo evaluation of HYNIC- and (Nalpha-His)acetic acid-modified [D-Glu1]-minigastrin. Bioconjugate chemistry. 2004 Jul; 15(4):864-71. doi: 10.1021/bc0300807. [PMID: 15264875]