Glycochenodeoxycholic acid (BioDeep_00000404224)
Main id: BioDeep_00000001652
Secondary id: BioDeep_00000229659
natural product PANOMIX_OTCML-2023 Bile acids
代谢物信息卡片
Chenodeoxycholic acid glycine conjugate
化学式: C26H43NO5 (449.31410680000005)
中文名称: 甘氨鹅脱氧胆酸
谱图信息:
最多检出来源 Homo sapiens(blood) 1.16%
Reviewed
Last reviewed on 2024-07-17.
Cite this Page
Glycochenodeoxycholic acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/glycochenodeoxycholic_acid (retrieved
2024-09-17) (BioDeep RN: BioDeep_00000404224). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: CC(CCC(=O)NCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C
InChI: InChI=1S/C26H43NO5/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16+,17-,18-,19+,20+,21-,24+,25+,26-/m1/s1
描述信息
A bile acid glycine conjugate having 3alpha,7alpha-dihydroxy-5beta-cholan-24-oyl as the bile acid component.
Chenodeoxycholic acid glycine conjugate is an acyl glycine and a bile acid-glycine conugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic environment. In hepatocytes, both primary and secondary bile acids undergo amino acid conjugation at the C-24 carboxylic acid on the side chain, and almost all bile acids in the bile duct therefore exist in a glycine conjugated form (PMID:16949895). This compound usually exists as the sodium salt and acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic. [HMDB]
Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis[1][2].
同义名列表
数据库引用编号
42 个数据库交叉引用编号
- ChEBI: CHEBI:36274
- KEGG: C05466
- PubChem: 12544
- DrugBank: DB02123
- ChEMBL: CHEMBL1552
- MeSH: Glycochenodeoxycholic Acid
- foodb: FDB022157
- CAS: 640-79-9
- MoNA: CCMSLIB00005435453
- MoNA: CCMSLIB00005435454
- MoNA: CCMSLIB00005435455
- MoNA: CCMSLIB00005435510
- MoNA: CCMSLIB00005435511
- MoNA: CCMSLIB00005435512
- MoNA: MoNA038325
- MoNA: MoNA038155
- MoNA: MoNA038003
- MoNA: MoNA037574
- MoNA: MoNA037271
- MoNA: MoNA035442
- MoNA: MoNA035440
- MoNA: MoNA035438
- MoNA: MoNA035025
- MoNA: MoNA035024
- MoNA: MoNA035022
- MoNA: MoNA034401
- MoNA: MoNA034400
- MoNA: MoNA034398
- MoNA: MoNA033259
- MoNA: MoNA033257
- MoNA: MoNA033253
- MoNA: MoNA032377
- MoNA: MoNA032374
- MoNA: MoNA032373
- MoNA: CCMSLIB00001059061
- MetaboLights: MTBLC36274
- LipidMAPS: LMST05030008
- PDB-CCD: CHO
- 3DMET: B05043
- NIKKAJI: J22.601G
- RefMet: Glycochenodeoxycholic acid
- medchemexpress: HY-N2334
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 9606 Homo sapiens: 10.1007/S11306-016-1051-4
- 9606 Homo sapiens: 10.1007/S11306-016-1051-4
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yueying Zhao, Cheng Xi, Donghan Liu, Xiaoqiao Ren, Jiayi Fan, Jakkree Tangthianchaichana, Yang Lu, Huichao Wu. Chemical components with antibacterial properties found in sanchen powder from traditional Tibetan medicine.
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Food & function.
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