Reduced glutathione (BioDeep_00000400070)

Main id: BioDeep_00000002796

 

natural product PANOMIX_OTCML-2023


代谢物信息卡片


N5-((R)-1-((Carboxymethyl)amino)-3-mercapto-1-oxopropan-2-yl)-L-glutamine

化学式: C10H17N3O6S (307.08380220000004)
中文名称: 谷胱甘肽(还原型)
谱图信息: 最多检出来源 Homo sapiens(blood) 0.18%

Reviewed

Last reviewed on 2024-07-15.

Cite this Page

Reduced glutathione. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/reduced_glutathione (retrieved 2024-09-17) (BioDeep RN: BioDeep_00000400070). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C(CC(=O)NC(CS)C(=O)NCC(=O)O)C(C(=O)O)N
InChI: InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1

描述信息

A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine.

L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

同义名列表

9 个代谢物同义名

Glutathione; Glutathione reduced; Reduced glutathione; Reduced Glutathione + H+; Glutathione (reduced from); Glucosidetathione(reduced form); GSH; γ-L-Glutamyl-L-cysteinyl-glycine; L-Glutathione reduced



数据库引用编号

71 个数据库交叉引用编号

分类词条

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Fanai Lalsangpuii, Samuel Lalthazuala Rokhum, Fanai Nghakliana, Joseph V L Ruatpuia, Lalchhandami Tochhawng, Amit Kumar Trivedi, Ralte Lalfakzuala, Zothan Siama. Mikania micrantha silver nanoparticles exhibit anticancer activities against human lung adenocarcinoma via caspase-mediated apoptotic cell death. Artificial cells, nanomedicine, and biotechnology. 2024 Dec; 52(1):186-200. doi: 10.1080/21691401.2024.2325942. [PMID: 38465883]
  • Nesma Khaled, Nehal Ibrahim, Alaa E Ali, Fadia S Youssef, Sherweit H El-Ahmady. LC-qTOF-MS/MS phytochemical profiling of Tabebuia impetiginosa (Mart. Ex DC.) Standl. leaf and assessment of its neuroprotective potential in rats. Journal of ethnopharmacology. 2024 Sep; 331(?):118292. doi: 10.1016/j.jep.2024.118292. [PMID: 38705428]
  • Feiyu Tang, Bin Wang, Jinpeng Li, Jun Xu, Jinsong Zeng, Wenhua Gao, Kefu Chen. Water-soluble silver nanoclusters with multicolor fluorescence generated by dialdehyde nanofibrillated cellulose for biological imaging. Carbohydrate polymers. 2024 Jul; 336(?):122138. doi: 10.1016/j.carbpol.2024.122138. [PMID: 38670763]
  • Yulia N Cajas, Karina Cañón-Beltrán, Rosane Mazzarella, Carolina Nuñez-Puente, Encina M González, Heriberto Rodriguez-Martinez, Dimitrios Rizos, Cristina A Martinez-Serrano. Nobiletin as a novel agent to enhance porcine in vitro embryo development and quality. Theriogenology. 2024 Jul; 223(?):36-46. doi: 10.1016/j.theriogenology.2024.04.011. [PMID: 38669840]
  • Zemin Yang, Jialu Wang, Wenjun Wang, Haobo Zhang, Yuhan Wu, Xusheng Gao, Dan Gao, Xiwen Li. Physiological, cytological and multi-omics analysis revealed the molecular response of Fritillaria cirrhosa to Cd toxicity in Qinghai-Tibet Plateau. Journal of hazardous materials. 2024 Jul; 472(?):134611. doi: 10.1016/j.jhazmat.2024.134611. [PMID: 38754230]
  • Wang Gao, Dengyun Wu, Dan Zhang, Zixin Geng, Mengting Tong, Yusui Duan, Wansheng Xia, Jianzhou Chu, Xiaoqin Yao. Comparative analysis of the effects of microplastics and nitrogen on maize and wheat: Growth, redox homeostasis, photosynthesis, and AsA-GSH cycle. The Science of the total environment. 2024 Jul; 932(?):172555. doi: 10.1016/j.scitotenv.2024.172555. [PMID: 38677420]
  • Yanxiao Li, Guishuang Zhu, Haonan Sun, Dianjun Xiang, Chunlan Zhang, Zhigang Li, Peng Liu. Genome-wide analysis of LOG family genes in castor and RcLOG5 enhances drought, salt, and cold stress tolerance in Arabidopsis thaliana. Gene. 2024 Jun; 913(?):148398. doi: 10.1016/j.gene.2024.148398. [PMID: 38518901]
  • Qi Sun, Ting Zhang, Yuchen Ren, Yuan Qiu, Xiaogang Luo, Jingfang Yang, Genyan Liu. A two-photon fluorescent probe for highly selective detection of Cys over GSH and Hcy based on the Michael addition and transcyclization mechanism and its application in bioimaging and protein straining in SDS-PAGE. Analytica chimica acta. 2024 Jun; 1309(?):342687. doi: 10.1016/j.aca.2024.342687. [PMID: 38772659]
  • Zhengying Liu, Qian Bian, Dayong Wang. Exposure to 6-PPD quinone causes ferroptosis activation associated with induction of reproductive toxicity in Caenorhabditis elegans. Journal of hazardous materials. 2024 Jun; 471(?):134356. doi: 10.1016/j.jhazmat.2024.134356. [PMID: 38643579]
  • Probir Kumar Mittra, Md Atikur Rahman, Swapan Kumar Roy, Soo-Jeong Kwon, Sung Ho Yun, Cho Kun, Meiliang Zhou, Tomoyuki Katsube-Tanaka, Tatsuhiko Shiraiwa, Sun-Hee Woo. Deciphering proteomic mechanisms explaining the role of glutathione as an aid in improving plant fitness and tolerance against cadmium-toxicity in Brassica napus L. Journal of hazardous materials. 2024 Jun; 471(?):134262. doi: 10.1016/j.jhazmat.2024.134262. [PMID: 38640678]
  • Jinshuai Lan, Li Liu, Wenjun Zhao, Zhe Li, Ruifeng Zeng, Shiyuan Fang, Lixia Chen, Yi Shen, Hai Wei, Tong Zhang, Yue Ding. Unlocking the anticancer activity of gambogic acid: a shift towards ferroptosis via a GSH/Trx dual antioxidant system. Free radical biology & medicine. 2024 Jun; 218(?):26-40. doi: 10.1016/j.freeradbiomed.2024.03.023. [PMID: 38570172]
  • Lara Vogelsang, Jürgen Eirich, Iris Finkemeier, Karl-Josef Dietz. Specificity and dynamics of H2O2 detoxification by the cytosolic redox regulatory network as revealed by in vitro reconstitution. Redox biology. 2024 Jun; 72(?):103141. doi: 10.1016/j.redox.2024.103141. [PMID: 38599017]
  • Guillermo Reséndiz-González, Agustín Olmedo-Juárez, Roberto González-Garduño, Jorge Alberto Cortes-Morales, Manasés González-Cortazar, Ana Elvia Sánchez-Mendoza, María Eugenia López-Arellano, Crisóforo Mercado-Márquez, Alejandro Lara-Bueno, Rosa Isabel Higuera-Piedrahita. Anthelmintic efficacy of an organic fraction from Guazuma ulmifolia leaves and evaluation of reactive oxidative stress on Haemonchus contortus. Experimental parasitology. 2024 Jun; 261(?):108768. doi: 10.1016/j.exppara.2024.108768. [PMID: 38679124]
  • Weijuan Zou, Feng Gao, Zheying Meng, Xiaojun Cai, Wu Chen, Yuanyi Zheng, Tao Ying, Longchen Wang, Jianrong Wu. Lactic acid responsive sequential production of hydrogen peroxide and consumption of glutathione for enhanced ferroptosis tumor therapy. Journal of colloid and interface science. 2024 Jun; 663(?):787-800. doi: 10.1016/j.jcis.2024.03.001. [PMID: 38442520]
  • Shanwei Wang, Wei Xing, Wei Li, Zuoming Xie, Yuan Xiao, Wenmin Huang. Red light mitigates Cd toxicity in Egeria densa by restricting Cd accumulation and modulating antioxidant defense system. Plant physiology and biochemistry : PPB. 2024 Jun; 211(?):108675. doi: 10.1016/j.plaphy.2024.108675. [PMID: 38705047]
  • Shunsuke Miyaji, Takehiro Ito, Taisuke Kitaiwa, Kosuke Nishizono, Shin-Ichiro Agake, Hiroki Harata, Haruna Aoyama, Minori Umahashi, Muneo Sato, Jun Inaba, Shinya Fushinobu, Tadashi Yokoyama, Akiko Maruyama-Nakashita, Masami Yokota Hirai, Naoko Ohkama-Ohtsu. N2-Acetylornithine deacetylase functions as a Cys-Gly dipeptidase in the cytosolic glutathione degradation pathway in Arabidopsis thaliana. The Plant journal : for cell and molecular biology. 2024 Jun; 118(5):1603-1618. doi: 10.1111/tpj.16700. [PMID: 38441834]
  • Feng-Juan Li, Shouzhi Fu, Hua Ye, Yi-Han Hu, Jianxin Chen, Jamie R Privratsky, Wei Yu, Feng Dong, Russel J Reiter, Maolong Dong, Jun Guo, Jun Ren. Metallothionein Alleviates Glutathione Depletion-Induced Oxidative Cardiomyopathy through CISD1-Dependent Regulation of Ferroptosis in Murine Hearts. The American journal of pathology. 2024 Jun; 194(6):912-926. doi: 10.1016/j.ajpath.2024.02.009. [PMID: 38417695]
  • Zhu Sixi, Suxia Sun, Wei Zhao, Xiuqin Yang, Huan Mao, Luying Sheng. Comprehensive physiology and proteomics analysis revealed the molecular toxicological mechanism of Se stress on indica and japonica rice. Chemosphere. 2024 Jun; 358(?):142190. doi: 10.1016/j.chemosphere.2024.142190. [PMID: 38685336]
  • Shunshun Jin, Haoxiang Xu, Chengbo Yang, Karmin O. Regulation of oxidative stress in the intestine of piglets after enterotoxigenic Escherichia coli (ETEC) infection. Biochimica et biophysica acta. Molecular cell research. 2024 Jun; 1871(5):119711. doi: 10.1016/j.bbamcr.2024.119711. [PMID: 38574824]
  • Khamsalath Soudthedlath, Toshiki Nakamura, Tsukasa Ushiwatari, Jutarou Fukazawa, Keishi Osakabe, Yuriko Osakabe, Akiko Maruyama-Nakashita. SULTR2;1 Adjusts the Bolting Timing by Transporting Sulfate from Rosette Leaves to the Primary Stem. Plant & cell physiology. 2024 May; 65(5):770-780. doi: 10.1093/pcp/pcae020. [PMID: 38424724]
  • Noppawan Phumala Morales, Witcharat Loahachanwanich, Ekkapoj Korwutthikulrangsri, Monchai Ruangchainikom, Werasak Sutipornpalangkul. Lipid Peroxidation, Reduced Glutathione, and Glutathione Peroxidase Levels in Intervertebral Discs of Patients with Lumbar Degenerative Disc Disease. Medical science monitor : international medical journal of experimental and clinical research. 2024 May; 30(?):e944335. doi: 10.12659/msm.944335. [PMID: 38783538]
  • Margarita Hernandez-Mixteco, Blandina Bernal-Morales, Olga Lidia Valenzuela, Juan Francisco Rodríguez-Landa, Jorge Francisco Cerna-Cortes, Eliud Alfredo García-Montalvo. Effect of Cucurbita ficifolia Bouché on glutathione level and glycosylated hemoglobin percentage in a Mexican rural population with type 2 diabetes. Journal of ethnopharmacology. 2024 May; 326(?):117924. doi: 10.1016/j.jep.2024.117924. [PMID: 38369067]
  • Wenwen Li, Yu Wang, Yun Zhang, Yuwen Fan, Jinsong Liu, Ke Zhu, Shu Jiang, Jinao Duan. Lizhong decoction ameliorates ulcerative colitis by inhibiting ferroptosis of enterocytes via the Nrf2/SLC7A11/GPX4 pathway. Journal of ethnopharmacology. 2024 May; 326(?):117966. doi: 10.1016/j.jep.2024.117966. [PMID: 38401661]
  • Antonius T M Van Kessel, Gonzalo Cosa. Lipid-derived electrophiles inhibit the function of membrane channels during ferroptosis. Proceedings of the National Academy of Sciences of the United States of America. 2024 May; 121(21):e2317616121. doi: 10.1073/pnas.2317616121. [PMID: 38743627]
  • Ya-Xuan Liang, Xue-Yi Sun, De-Zhong Xu, Yi-Nan Gao, Quan Tang, Zhong-Lin Lu, Yang Liu. Codelivery of CPT and siPHB1 with GSH/ROS Dual-Responsive Hybrid Nanoparticles Based on a [12]aneN3-Derived Lipid for Synergistic Lung Cancer Therapy. ACS applied bio materials. 2024 May; 7(5):3202-3214. doi: 10.1021/acsabm.4c00206. [PMID: 38651918]
  • Dadi Jiang, Youming Guo, Tianyu Wang, Liang Wang, Yuelong Yan, Ling Xia, Rakesh Bam, Zhifen Yang, Hyemin Lee, Takao Iwawaki, Boyi Gan, Albert C Koong. IRE1α determines ferroptosis sensitivity through regulation of glutathione synthesis. Nature communications. 2024 May; 15(1):4114. doi: 10.1038/s41467-024-48330-0. [PMID: 38750057]
  • Gang Tan, Guanghui Hou, Junmin Qian, Yaping Wang, Weijun Xu, Wenjuan Luo, Xiaobing Chen, Aili Suo. Hyaluronan-decorated copper-doxorubicin-anlotinib nanoconjugate for targeted synergistic chemo/chemodynamic/antiangiogenic tritherapy against hepatocellular carcinoma. Journal of colloid and interface science. 2024 May; 662(?):857-869. doi: 10.1016/j.jcis.2024.02.085. [PMID: 38382370]
  • Dan Zhang, Lulu Zhang, Chengwei Yuan, Kuizhi Zhai, Wansheng Xia, Yusui Duan, Bingnan Zhao, Jianzhou Chu, Xiaoqin Yao. Brassinolide as potential rescue agent for Pinellia ternata grown under microplastic condition: Insights into their modulatory role on photosynthesis, redox homeostasis, and AsA-GSH cycling. Journal of hazardous materials. 2024 May; 470(?):134116. doi: 10.1016/j.jhazmat.2024.134116. [PMID: 38547753]
  • Jacques Dupuy, Edwin Fouché, Céline Noirot, Pierre Martin, Charline Buisson, Françoise Guéraud, Fabrice Pierre, Cécile Héliès-Toussaint. A dual model of normal vs isogenic Nrf2-depleted murine epithelial cells to explore oxidative stress involvement. Scientific reports. 2024 05; 14(1):10905. doi: 10.1038/s41598-024-60938-2. [PMID: 38740939]
  • David Calderón Guzmán, Norma Osnaya Brizuela, Maribel Ortíz Herrera, Hugo Juárez Olguín, Armando Valenzuela Peraza, Norma Labra Ruíz, Gerardo Barragán Mejía. Intake of oligoelements with cytarabine or etoposide alters dopamine levels and oxidative damage in rat brain. Scientific reports. 2024 05; 14(1):10835. doi: 10.1038/s41598-024-61766-0. [PMID: 38736022]
  • Tianyu Lou, Hao Wu, Menghan Feng, Lirong Liu, Xiaoqin Yang, Mingxia Pan, Zuying Wei, Yinhuan Zhang, Lixia Shi, Biqiong Qu, Haolan Yang, Shiyu Cong, Kui Chen, Jie Liu, Yueting Li, Zhixin Jia, Hongbin Xiao. Integration of metabolomics and transcriptomics reveals that Da Chuanxiong Formula improves vascular cognitive impairment via ACSL4/GPX4 mediated ferroptosis. Journal of ethnopharmacology. 2024 May; 325(?):117868. doi: 10.1016/j.jep.2024.117868. [PMID: 38325668]
  • Minling Gao, Hongchang Peng, Xuesong Zhao, Zhengzhen Xiao, Weiwen Qiu, Zhengguo Song. Effect of cadmium on polystyrene transport in parsley roots planted in a split-root system and assessment of the combined toxic effects. The Science of the total environment. 2024 May; 924(?):171633. doi: 10.1016/j.scitotenv.2024.171633. [PMID: 38471591]
  • Hailian Bi, Shibin Guo, Yan Wang, Zhijie Liu, Guokai Wu, Xiaokui Huo, Li Guo, Huishu Guo, Yongjian Xiong. Pinobanksin ameliorated DSS-induced acute colitis mainly through modulation of SLC7A11/glutathione-mediated intestinal epithelial ferroptosis. Food & function. 2024 May; 15(9):4970-4982. doi: 10.1039/d3fo04500e. [PMID: 38606509]
  • Zhao Qian, Liu Lu, Wei Zihan, Bai Qianyue, Zhao Chungang, Zhang Shuheng, Pan Jiali, Yu Jiaxin, Zhang Shuang, Wei Jian. Gamma-aminobutyric acid (GABA) improves salinity stress tolerance in soybean seedlings by modulating their mineral nutrition, osmolyte contents, and ascorbate-glutathione cycle. BMC plant biology. 2024 May; 24(1):365. doi: 10.1186/s12870-024-05023-6. [PMID: 38706002]
  • Jasvinder Kaur, Nikita Tiwari, Mehar Hasan Asif, Varsha Dharmesh, Mariya Naseem, Pankaj Kumar Srivastava, Suchi Srivastava. Integrated genome-transcriptome analysis unveiled the mechanism of Debaryomyces hansenii-mediated arsenic stress amelioration in rice. Journal of hazardous materials. 2024 May; 469(?):133954. doi: 10.1016/j.jhazmat.2024.133954. [PMID: 38484657]
  • Yi Jiang, Xiaofei Chen, Xuesong Cao, Chuanxi Wang, Le Yue, Xiaona Li, Zhenyu Wang. Mechanistic insight into the intensification of arsenic toxicity to rice (Oryza sativa L.) by nanoplastic: Phytohormone and glutathione metabolism modulation. Journal of hazardous materials. 2024 May; 469(?):134086. doi: 10.1016/j.jhazmat.2024.134086. [PMID: 38521034]
  • Christine H Foyer, Karl Kunert. The ascorbate-glutathione cycle coming of age. Journal of experimental botany. 2024 May; 75(9):2682-2699. doi: 10.1093/jxb/erae023. [PMID: 38243395]
  • Mohamed A Radwan, Amira F Gad, Amira M Abd El-Aziz, Kawther S El-Gendy. Does commercial indoxacarb pose ecotoxicological consequences? Employing a multi-marker approach in the model species Theba pisana. Environmental science and pollution research international. 2024 May; 31(22):31911-31924. doi: 10.1007/s11356-024-33214-z. [PMID: 38641691]
  • Tatiana Recabarren-Villalón, Ana C Ronda, Lautaro Girones, Jorge Marcovecchio, Martín Amodeo, Andrés H Arias. Can environmental factors increase oxidative responses in fish exposed to polycyclic aromatic hydrocarbons (PAHs)?. Chemosphere. 2024 May; 355(?):141793. doi: 10.1016/j.chemosphere.2024.141793. [PMID: 38548075]
  • Laila Mowafy, Manal Abdul-Hamid, Nadia Moustafa, Saleh Al-Quraishy, Abdel-Azeem S Abdel-Baki, Mohamed Y Zaky, Abdul-Mawgoud A Asran, Heba Abdel-Tawab. Repurposing the drug, amprolium as a novel molluscicide against the land snail (Eobania vermiculata). Pesticide biochemistry and physiology. 2024 May; 201(?):105889. doi: 10.1016/j.pestbp.2024.105889. [PMID: 38685220]
  • Evgenia S Seryogina, Anna V Kamynina, Dmitry O Koroev, Olga M Volpina, Andrey Y Vinokurov, Andrey Y Abramov. RAGE induces physiological activation of NADPH oxidase in neurons and astrocytes and neuroprotection. The FEBS journal. 2024 May; 291(9):1944-1957. doi: 10.1111/febs.17086. [PMID: 38335056]
  • Man Yuan, Feng Wang, Tieqiang Sun, Xiangyu Bian, Yuxian Zhang, Changjiang Guo, Lixia Yu, Zhanxin Yao. Vitamin B6 alleviates chronic sleep deprivation-induced hippocampal ferroptosis through CBS/GSH/GPX4 pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 May; 174(?):116547. doi: 10.1016/j.biopha.2024.116547. [PMID: 38599059]
  • Rongliang Tong, Xiaode Feng, Jingqi Sun, Zhenan Ling, Jun Wang, Shun Li, Beng Yang, Junfang Deng, Guijin He, Jian Wu. Co-Delivery of siNRF2 and Sorafenib by a 'Click' Dual Functioned Hyperbranched Nanocarrier for Synergistically Inducing Ferroptosis in Hepatocellular Carcinoma. Small (Weinheim an der Bergstrasse, Germany). 2024 May; 20(21):e2307273. doi: 10.1002/smll.202307273. [PMID: 38102096]
  • Hossam El Din H Abdelhafez, Amr A Abdallah, Reda K Abdel-Razik, Nadia A Hamed, Ahmed Elshatory, Walaa Awad, Abdel Azeim A Khalaf, Aya M Mekkawy. Sex comparison of oxidative stress, mitochondrial dysfunction, and apoptosis triggers induced by single-dose Abamectin in albino rats. Pesticide biochemistry and physiology. 2024 May; 201(?):105903. doi: 10.1016/j.pestbp.2024.105903. [PMID: 38685225]
  • Chongmei Tian, Yu Qiu, Yaping Zhao, Liping Fu, Daozong Xia, Junjie Ying. Selenium protects against Pb-induced renal oxidative injury in weaning rats and human renal tubular epithelial cells through activating NRF2. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). 2024 May; 83(?):127420. doi: 10.1016/j.jtemb.2024.127420. [PMID: 38432121]
  • Yu-Hsin Chen, I-Ju Liu, Tzu-Chen Lin, Min-Chen Tsai, Shang-Hsiu Hu, Tsai-Ching Hsu, Yi-Ting Wu, Bor-Show Tzang, Wen-Hsuan Chiang. PEGylated chitosan-coated nanophotosensitizers for effective cancer treatment by photothermal-photodynamic therapy combined with glutathione depletion. International journal of biological macromolecules. 2024 May; 266(Pt 2):131359. doi: 10.1016/j.ijbiomac.2024.131359. [PMID: 38580018]
  • Roghayeh Rashidi, Ali Roohbakhsh, Leila Mohtashami, Leila Mobasheri, Hamidreza Kheradmand, Mohammad Sadegh Amiri, Ahmad Ghorbani, Seyed Hadi Mousavi. Cytotoxic and apoptotic effects of Ferula gummosa Boiss: extract on human breast adenocarcinoma cell line. Molecular biology reports. 2024 Apr; 51(1):592. doi: 10.1007/s11033-024-09364-1. [PMID: 38683376]
  • Minghua Zhang, Xianxian Yao, Jian Xu, Jiaying Song, Shuting Mai, Weichu Zhu, Yichen Zhang, Liangliang Zhu, Wuli Yang. Biodegradable zwitterionic polymer-cloaked defective metal-organic frameworks for ferroptosis-inducing cancer therapy. International journal of pharmaceutics. 2024 Apr; 655(?):124032. doi: 10.1016/j.ijpharm.2024.124032. [PMID: 38521374]
  • Meitong Guo, Xingchen Du, Xiaoyan Wang. Inhibition of ferroptosis: A new direction in the treatment of ulcerative colitis by traditional Chinese medicine. Journal of ethnopharmacology. 2024 Apr; 324(?):117787. doi: 10.1016/j.jep.2024.117787. [PMID: 38253272]
  • Yuanding Zeng, Wangjie Cao, Yong Huang, Han Zhang, Congyi Li, Jianzheng He, Yongqi Liu, Hongxia Gong, Yun Su. Huangqi Baihe Granules alleviate hypobaric hypoxia-induced acute lung injury in rats by suppressing oxidative stress and the TLR4/NF-κB/NLRP3 inflammatory pathway. Journal of ethnopharmacology. 2024 Apr; 324(?):117765. doi: 10.1016/j.jep.2024.117765. [PMID: 38228230]
  • María Elena Soto, Israel Pérez-Torres, Linaloe Manzano-Pech, Adrían Palacios-Chavarría, Rafael Ricardo Valdez-Vázquez, Verónica Guarner-Lans, Elizabeth Soria-Castro, Eulises Díaz-Díaz, Vicente Castrejón-Tellez. Redox Homeostasis Alteration Is Restored through Melatonin Treatment in COVID-19 Patients: A Preliminary Study. International journal of molecular sciences. 2024 Apr; 25(8):. doi: 10.3390/ijms25084543. [PMID: 38674128]
  • Mengyuan Zhou, Yu Cao, Shaocheng Xie, Yannan Xiang, Mengxin Li, Haitao Yang, Zibo Dong. Gypenoside XLIX alleviates acute liver injury: Emphasis on NF-κB/PPAR-α/NLRP3 pathways. International immunopharmacology. 2024 Apr; 131(?):111872. doi: 10.1016/j.intimp.2024.111872. [PMID: 38503011]
  • Sitong Lai, Bing Wang, Kunhui Sun, Fan Li, Qian Liu, Xie-An Yu, Lihe Jiang, Lisheng Wang. Self-Assembled Matrine-PROTAC Encapsulating Zinc(II) Phthalocyanine with GSH-Depletion-Enhanced ROS Generation for Cancer Therapy. Molecules (Basel, Switzerland). 2024 Apr; 29(8):. doi: 10.3390/molecules29081845. [PMID: 38675664]
  • Finja Bohle, Alina Klaus, Julian Ingelfinger, Hendrik Tegethof, Nassim Safari, Markus Schwarzländer, Frank Hochholdinger, Matthias Hahn, Andreas J Meyer, Ivan F Acosta, Stefanie J Müller-Schüssele. Contrasting cytosolic glutathione redox dynamics under abiotic and biotic stress in barley as revealed by the biosensor Grx1-roGFP2. Journal of experimental botany. 2024 Apr; 75(8):2299-2312. doi: 10.1093/jxb/erae035. [PMID: 38301663]
  • Hend A Essa, Alaa M Ali, Mona A Saied. Cymbopogon proximus and Petroselinum crispum seed ethanolic extract/Gum Arabic nanogel emulsion: Preventing ethylene glycol and ammonium chloride-induced urolithiasis in rats. Urolithiasis. 2024 Apr; 52(1):52. doi: 10.1007/s00240-024-01559-2. [PMID: 38564033]
  • Diego Ortiz da Silva, Jonathan Ratko, Ana Paula Nascimento Côrrea, Niumaique Gonçalves da Silva, Diego Mauro Carneiro Pereira, Ieda Cristina Schleger, Ananda Karla Alvez Neundorf, Maria Rosa Dmengeon Pedreiro de Souza, Tatiana Herrerias, Lucélia Donatti. Assessing physiological responses and oxidative stress effects in Rhamdia voulezi exposed to high temperatures. Fish physiology and biochemistry. 2024 Apr; 50(2):617-633. doi: 10.1007/s10695-023-01294-2. [PMID: 38175338]
  • Yu Sun, Qingfang Deng, Qiurong Zhang, Xin Zhou, Ruhai Chen, Siyu Li, Qing Wu, Huaguo Chen. Hazards of microplastics exposure to liver function in fishes: A systematic review and meta-analysis. Marine environmental research. 2024 Apr; 196(?):106423. doi: 10.1016/j.marenvres.2024.106423. [PMID: 38442589]
  • Amritha Jagannivasan, Sumithra Thangalazhy Gopakumar, Krupesha Sharma S R, Gayathri Suresh, Dhanutha Nikathil Raveendranathan, Reynold Peter, Ambarish Purackattu Gop, Gopalakrishnan Achamveetil. Profiling the antioxidant biomarkers in marine fish larvae: a comparative assessment of different storage conditions to select the optimal strategy. Fish physiology and biochemistry. 2024 Apr; 50(2):557-574. doi: 10.1007/s10695-023-01290-6. [PMID: 38193995]
  • Samet Tekin, Emin Sengul, Serkan Yildirim, Emrah Hicazi Aksu, İsmail Bolat, Burak Çınar, Azizeh Shadidizaji, Fikret Çelebi, Mohamad Warda. Molecular insights into the antioxidative and anti-inflammatory effects of P-coumaric acid against bisphenol A-induced testicular injury: In vivo and in silico studies. Reproductive toxicology (Elmsford, N.Y.). 2024 Apr; 125(?):108579. doi: 10.1016/j.reprotox.2024.108579. [PMID: 38513920]
  • Junli Shao, Chengze Lai, Qiuyi Zheng, Yu Luo, Chengji Li, Bin Zhang, Yanqin Sun, Shizhen Liu, Yingying Shi, Jinglin Li, Zuguo Zhao, Lianxian Guo. Effects of dietary arsenic exposure on liver metabolism in mice. Ecotoxicology and environmental safety. 2024 Apr; 274(?):116147. doi: 10.1016/j.ecoenv.2024.116147. [PMID: 38460405]
  • Nan Geng, Siyuan Dong, Pengpeng Xie, Yi Zhang, Rong Shi, Chen Chen, Zhao Xu, Qun Chen. Excessive fluoride induces ovarian function impairment by regulating levels of ferroptosis in fluorosis women and ovarian granulosa cells. Reproductive toxicology (Elmsford, N.Y.). 2024 Apr; 125(?):108556. doi: 10.1016/j.reprotox.2024.108556. [PMID: 38342390]
  • Muhammed Mehdi Üremiş, Yusuf Türköz, Nuray Üremiş. Investigation of apoptotic effects of Cucurbitacin D, I, and E mediated by Bax/Bcl-xL, caspase-3/9, and oxidative stress modulators in HepG2 cell line. Drug development research. 2024 Apr; 85(2):e22174. doi: 10.1002/ddr.22174. [PMID: 38494997]
  • Zhilin Ni, Jinhu Liu, Wenting Cui, Liang Cao, Shuozeng Dou. Interactive impacts of CO2-induced seawater acidification and cadmium exposure on antioxidant defenses of juvenile tongue sole Cynoglossus semilaevis. Marine pollution bulletin. 2024 Apr; 201(?):116284. doi: 10.1016/j.marpolbul.2024.116284. [PMID: 38522335]
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  • Zengyao Tang, Xin Huang, Hanying Mei, Zeqi Zheng. Silencing of METTL3 suppressed ferroptosis of myocardial cells by m6A modification of SLC7A11 in a YTHDF2 manner. Journal of bioenergetics and biomembranes. 2024 Apr; 56(2):149-157. doi: 10.1007/s10863-024-10006-1. [PMID: 38319402]
  • Mohamed H Elashal, Aida A Abd El-Wahed, Mostafa Abdelgaber Mohamed, Rania Hamad, Mabrouk Attia Abd Eldaim, Shaden A M Khalifa, Badr Aldahmash, Hesham R El-Seedi, Bishoy El-Aarag. Apilarnil ameliorates Bisphenol A-induced testicular toxicity in adult male rats via improving antioxidant potency and PCNA expression. Reproductive toxicology (Elmsford, N.Y.). 2024 Apr; 125(?):108570. doi: 10.1016/j.reprotox.2024.108570. [PMID: 38484946]
  • Yunong Ma, Xi Zhao, Peilin Tian, Kexin Xu, Jiayang Luo, Honghui Li, Mingqing Yuan, Xu Liu, Yanping Zhong, Pingzhen Wei, Jiaxing Song, Liewei Wen, Cuixia Lu. Laser-Ignited Lipid Peroxidation Nanoamplifiers for Strengthening Tumor Photodynamic Therapy Through Aggravating Ferroptotic Propagation and Sustainable High Immunogenicity. Small (Weinheim an der Bergstrasse, Germany). 2024 Apr; 20(14):e2306402. doi: 10.1002/smll.202306402. [PMID: 37992239]
  • Gang He, Yiyuan Zhang, Yanjiao Feng, Tangcong Chen, Mei Liu, Yue Zeng, Xiaojing Yin, Shaokui Qu, Lifen Huang, Youqiang Ke, Li Liang, Jun Yan, Wei Liu. SBFI26 induces triple-negative breast cancer cells ferroptosis via lipid peroxidation. Journal of cellular and molecular medicine. 2024 Apr; 28(7):e18212. doi: 10.1111/jcmm.18212. [PMID: 38516826]
  • Ágnes Jakab, Kinga Csillag, Károly Antal, Imre Boczonádi, Renátó Kovács, István Pócsi, Tamás Emri. Total transcriptome response for tyrosol exposure in Aspergillus nidulans. Fungal biology. 2024 04; 128(2):1664-1674. doi: 10.1016/j.funbio.2024.01.003. [PMID: 38575239]
  • Chunxiang Guo, Wei Zhao, Wei Wang, Zheng Yao, Wenhui Chen, Xiaoyi Feng. Study on the Antitumor Mechanism of Tanshinone IIA In Vivo and In Vitro through the Regulation of PERK-ATF4-HSPA5 Pathway-Mediated Ferroptosis. Molecules (Basel, Switzerland). 2024 Mar; 29(7):. doi: 10.3390/molecules29071557. [PMID: 38611836]
  • Lynda Sabrina Ounaceur, Mahfoud Messarah, Abdelaziz Lankar, Djihane Touaibia, Hanene Ghadab, Zohir Garri, Sonia Boudjil, Khadidja Belkacem Djeffel, Latifa Atoui, Anis Ounaceur, Nesrine Djaber, Amel Boumendjel. In vivo determination of the anti-inflammatory and antioxidant effects of the aqueous extract of Syzygium aromaticum (clove) in an asthmatic rat model. Cellular and molecular biology (Noisy-le-Grand, France). 2024 Mar; 70(3):29-39. doi: 10.14715/cmb/2024.70.3.5. [PMID: 38650159]
  • Wei Wu, Wenhao Bu, Yongxing Tan, Yongwang Wang. Effect of sulfasalazine on ferroptosis during intestinal injury in rats after liver transplantation. Scientific reports. 2024 03; 14(1):7349. doi: 10.1038/s41598-024-58057-z. [PMID: 38538748]
  • Ming-Chang Tsai, Chi-Chih Wang, I-Ning Tsai, Meng-Hsun Yu, Mon-Yuan Yang, Yi-Ju Lee, Kuei-Chuan Chan, Chau-Jong Wang. Improving the Effects of Mulberry Leaves and Neochlorogenic Acid on Glucotoxicity-Induced Hepatic Steatosis in High Fat Diet Treated db/db Mice. Journal of agricultural and food chemistry. 2024 Mar; 72(12):6339-6346. doi: 10.1021/acs.jafc.3c09033. [PMID: 38488910]
  • Begümhan Ömeroğlu Gülada, Muhammet Emin Cam, Meral Yüksel, Dilek Akakın, Turgut Taşkın, Gizem Emre, Göksel Şener, Berna Karakoyun. Gilaburu (Viburnum opulus L.) fruit extract has potential therapeutic and prophylactic role in a rat model of acetic acid-induced oxidant colonic damage. Journal of ethnopharmacology. 2024 Mar; 322(?):117624. doi: 10.1016/j.jep.2023.117624. [PMID: 38128893]
  • Xiao Wang, Feiyan Qi, Ziqi Sun, Hongfei Liu, Yue Wu, Xiaohui Wu, Jing Xu, Hua Liu, Li Qin, Zhenyu Wang, Suling Sang, Wenzhao Dong, Bingyan Huang, Zheng Zheng, Xinyou Zhang. Transcriptome sequencing and expression analysis in peanut reveal the potential mechanism response to Ralstonia solanacearum infection. BMC plant biology. 2024 Mar; 24(1):207. doi: 10.1186/s12870-024-04877-0. [PMID: 38515036]
  • Xiaosheng Lin, Hongwu Chen, Tingting Deng, Binghui Cai, Yubin Xia, Lei Xie, Huaiming Wang, Cong Huang. Improved Immune Response for Colorectal Cancer Therapy Triggered by Multifunctional Nanocomposites with Self-Amplifying Antitumor Ferroptosis. ACS applied materials & interfaces. 2024 Mar; 16(11):13481-13495. doi: 10.1021/acsami.3c16813. [PMID: 38456402]
  • A Kumar, J K Prasad, S Verma, A Gattani, G D Singh, V K Singh. Evaluation of uterine antioxidants in bitches suffering from cystic endometrial hyperplasia-pyometra complex. Polish journal of veterinary sciences. 2024 Mar; 27(1):43-52. doi: 10.24425/pjvs.2024.149332. [PMID: 38511595]
  • Xiaoqin Wang, Mengting He, Yinmin Zhao, Jie He, Jiansen Huang, Lei Zhang, Zhigang Xu, Yuejun Kang, Peng Xue. Bimetallic PtPd Atomic Clusters as Apoptosis/Ferroptosis Inducers for Antineoplastic Therapy through Heterogeneous Catalytic Processes. ACS nano. 2024 Mar; 18(11):8083-8098. doi: 10.1021/acsnano.3c11610. [PMID: 38456744]
  • Jinzhen Wei, Gang Wang, Min Lai, Yipin Zhang, Fengru Li, Yongwang Wang, Yongxing Tan. Faecal Microbiota Transplantation Alleviates Ferroptosis after Ischaemic Stroke. Neuroscience. 2024 Mar; 541(?):91-100. doi: 10.1016/j.neuroscience.2024.01.021. [PMID: 38296019]
  • Angela Mungala Lengo, Ibrahim Mohamed, Jean-Claude Lavoie. Glutathione Supplementation Prevents Neonatal Parenteral Nutrition-Induced Short- and Long-Term Epigenetic and Transcriptional Disruptions of Hepatic H2O2 Metabolism in Guinea Pigs. Nutrients. 2024 Mar; 16(6):. doi: 10.3390/nu16060849. [PMID: 38542762]
  • Juntao Xu, Guoqiang Guan, Zhifei Ye, Cheng Zhang, Yibo Guo, Yuan Ma, Chang Lu, Lingling Lei, Xiao-Bing Zhang, Guosheng Song. Enhancing lipid peroxidation via radical chain transfer reaction for MRI guided and effective cancer therapy in mice. Science bulletin. 2024 Mar; 69(5):636-647. doi: 10.1016/j.scib.2023.12.036. [PMID: 38158292]
  • Fabien Segui, Boutaina Daher, Célia Gotorbe, Jacques Pouyssegur, Vincent Picco, Milica Vucetic. Revealing the Ferroptotic Phenotype of Medulloblastoma. Journal of visualized experiments : JoVE. 2024 Mar; ?(205):. doi: 10.3791/66645. [PMID: 38557602]
  • Fozia Ghouri, Samreen Sarwar, Lixia Sun, Muhammad Riaz, Fasih Ullah Haider, Humera Ashraf, Mingyu Lai, Muhammad Imran, Jingwen Liu, Shafaqat Ali, Xiangdong Liu, Muhammad Qasim Shahid. Silicon and iron nanoparticles protect rice against lead (Pb) stress by improving oxidative tolerance and minimizing Pb uptake. Scientific reports. 2024 03; 14(1):5986. doi: 10.1038/s41598-024-55810-2. [PMID: 38472251]
  • Fereshteh Badini, Abolfazl Bayrami, Mohammad Ali Mirshekar, Samira Shahraki, Hamed Fanaei. Levothyroxine attenuates behavioral impairment and improves oxidative stress and histological alteration 3-nitropropionic acid induced experimental Huntington's disease in rats. Behavioural brain research. 2024 Mar; 461(?):114864. doi: 10.1016/j.bbr.2024.114864. [PMID: 38220060]
  • Mervt M Almostafa, Maged E Mohamed, Nancy S Younis. Ameliorative effects of vanillin against pentylenetetrazole-induced epilepsy and associated memory loss in mice: The role of Nrf2/HO-1/NQO1 and HMGB1/RAGE/TLR4/NFκB pathways. International immunopharmacology. 2024 Mar; 129(?):111657. doi: 10.1016/j.intimp.2024.111657. [PMID: 38335655]
  • Siqi Chen, Jie Fan, Ping Xie, Jihae Ahn, Michelle Fernandez, Leah K Billingham, Jason Miska, Jennifer D Wu, Derek A Wainwright, Deyu Fang, Jeffrey A Sosman, Yong Wan, Yi Zhang, Navdeep S Chandel, Bin Zhang. CD8+ T cells sustain antitumor response by mediating crosstalk between adenosine A2A receptor and glutathione/GPX4. The Journal of clinical investigation. 2024 Mar; 134(8):. doi: 10.1172/jci170071. [PMID: 38441967]
  • Ray Singh Rathore, Manjari Mishra, Ashwani Pareek, Sneh Lata Singla-Pareek. A glutathione-independent DJ-1/Pfp1 domain containing glyoxalase III, OsDJ-1C, functions in abiotic stress adaptation in rice. Planta. 2024 Mar; 259(4):81. doi: 10.1007/s00425-023-04315-9. [PMID: 38438662]
  • Yue Xin, Xueqing Li, Kaixin Ping, Yannan Xiang, Mengxin Li, Xing Li, Haitao Yang, Jingquan Dong. Pesticide avermectin-induced hepatotoxicity and growth inhibition in carp: Ameliorative capacity and potential mechanisms of quercetin as a dietary additive. Aquatic toxicology (Amsterdam, Netherlands). 2024 Mar; 268(?):106859. doi: 10.1016/j.aquatox.2024.106859. [PMID: 38342007]
  • Sunjeet Kumar, Shihai Wang, Mengzhao Wang, Shah Zeb, Mohammad Nauman Khan, Yanli Chen, Guopeng Zhu, Zhixin Zhu. Enhancement of sweetpotato tolerance to chromium stress through melatonin and glutathione: Insights into photosynthetic efficiency, oxidative defense, and growth parameters. Plant physiology and biochemistry : PPB. 2024 Mar; 208(?):108509. doi: 10.1016/j.plaphy.2024.108509. [PMID: 38461751]
  • Diem-Kieu Nguyen, Tri-Phuong Nguyen, Yi-Rong Li, Masaru Ohme-Takagi, Zin-Huang Liu, Thach-Thao Ly, Van-Anh Nguyen, Ngoc-Nam Trinh, Hao-Jen Huang. Comparative study of two indoor microbial volatile pollutants, 2-Methyl-1-butanol and 3-Methyl-1-butanol, on growth and antioxidant system of rice (Oryza sativa) seedlings. Ecotoxicology and environmental safety. 2024 Mar; 272(?):116055. doi: 10.1016/j.ecoenv.2024.116055. [PMID: 38340597]
  • Ruijiao Lin, Zijie Jia, Hongbing Chen, Hongli Xiong, Cunhao Bian, Xin He, Bi Wei, Junfeng Fu, Minzhu Zhao, Jianbo Li. Ferrostatin‑1 alleviates liver injury via decreasing ferroptosis following ricin toxin poisoning in rat. Toxicology. 2024 Mar; 503(?):153767. doi: 10.1016/j.tox.2024.153767. [PMID: 38437911]
  • Ariane Coelho Ferraz, Marília Bueno da Silva Menegatto, Rafaela Lameira Souza Lima, Oluwashola Samuel Ola-Olub, Daniela Caldeira Costa, José Carlos de Magalhães, Izabela Maurício Rezende, Angelle Desiree LaBeaud, Thomas P Monath, Pedro Augusto Alves, Andréa Teixeira de Carvalho, Olindo Assis Martins-Filho, Betânia P Drumond, Cintia Lopes de Brito Magalhães. Yellow fever virus infection in human hepatocyte cells triggers an imbalance in redox homeostasis with increased reactive oxygen species production, oxidative stress, and decreased antioxidant enzymes. Free radical biology & medicine. 2024 03; 213(?):266-273. doi: 10.1016/j.freeradbiomed.2024.01.042. [PMID: 38278309]
  • Haiyan Zhu, Yenan Duan, Yijing Yang, Enqing Chen, Hanxin Huang, Xi Wang, Jie Zhou. Sodium aescinate induces renal toxicity by promoting Nrf2/GPX4-mediated ferroptosis. Chemico-biological interactions. 2024 Mar; 391(?):110892. doi: 10.1016/j.cbi.2024.110892. [PMID: 38364601]
  • Yalei Cao, Zirun Jin, Yu Xi, Jianxing Cheng, Zishui Fang, Qiancheng Zhao, Jiaming Weng, Jun Zhu, Yanlin Tang, Zhe Zhang, Hui Jiang. Roles of ferroptosis in type 1 diabetes induced spermatogenic dysfunction. Free radical biology & medicine. 2024 Mar; 214(?):193-205. doi: 10.1016/j.freeradbiomed.2024.02.006. [PMID: 38369075]
  • Fevzi Elbasan, Busra Arikan, Ceyda Ozfidan-Konakci, Aysenur Tofan, Evren Yildiztugay. Hesperidin and chlorogenic acid mitigate arsenic-induced oxidative stress via redox regulation, photosystems-related gene expression, and antioxidant efficiency in the chloroplasts of Zea mays. Plant physiology and biochemistry : PPB. 2024 Mar; 208(?):108445. doi: 10.1016/j.plaphy.2024.108445. [PMID: 38402801]
  • Yuanyuan Liu, Erya Xu, Yijun Fan, Linlong Xu, Jie Ma, Xuebing Li, Hui Wang, Siyu He, Ting Li, Yujiao Qin, Jingtao Xiao, Aoxue Luo. Transcriptomics combined with physiological analysis provided new insights into the Zn enrichment capacity and tolerance mechanism of Dendrobium denneanum Kerr. Plant science : an international journal of experimental plant biology. 2024 Mar; 340(?):111988. doi: 10.1016/j.plantsci.2024.111988. [PMID: 38232820]
  • Hao-Lan Yang, Jia-Min Yu, Fu Cao, Wu-Ye Li, Bin Li, Xiao Lei, Shi-Guang Li, Su Liu, Mao-Ye Li. Unclassified glutathione-S-transferase AiGSTu1 confers chlorantraniliprole tolerance in Agrotis ipsilon. Pest management science. 2024 Mar; 80(3):1107-1117. doi: 10.1002/ps.7841. [PMID: 37862262]
  • Ana Vuković Popović, Ivna Štolfa Čamagajevac, Rosemary Vuković, Magdalena Matić, Mirna Velki, Dharmendra K Gupta, Vlatko Galić, Zdenko Lončarić. Biochemical and molecular responses of the ascorbate-glutathione cycle in wheat seedlings exposed to different forms of selenium. Plant physiology and biochemistry : PPB. 2024 Mar; 208(?):108460. doi: 10.1016/j.plaphy.2024.108460. [PMID: 38447422]
  • Tian-Jiao Zhou, Meng-Meng Zhang, Dan-Meng Liu, Li-Ling Huang, Hai-Qing Yu, Yi Wang, Lei Xing, Hu-Lin Jiang. Glutathione depletion and dihydroorotate dehydrogenase inhibition actuated ferroptosis-augment to surmount triple-negative breast cancer. Biomaterials. 2024 Mar; 305(?):122447. doi: 10.1016/j.biomaterials.2023.122447. [PMID: 38154441]