pyridoxamine (BioDeep_00000399943)

Main id: BioDeep_00000001418

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019 Volatile Flavor Compounds


代谢物信息卡片


Pyridoxylamine

化学式: C8H12N2O2 (168.0898732)
中文名称: 吡多胺, 吡哆胺 二盐酸盐, 吡哆胺
谱图信息: 最多检出来源 Homo sapiens(blood) 0.77%

分子结构信息

SMILES: CC1=C(O)C(CN)=C(CO)C=N1
InChI: InChI=1S/C8H12N2O2/c1-5-8(12)7(2-9)6(4-11)3-10-5/h3,11-12H,2,4,9H2,1H3

描述信息

A monohydroxypyridine that is pyridine substituted by a hydroxy group at position 3, an aminomethyl group at position 4, a hydroxymethyl group at position 5 and a methyl group at position 2. The 4-aminomethyl form of vitamin B6, it is used (in the form of the hydrochloride salt) for treatment of diabetic nephropathy.
D018977 - Micronutrients > D014815 - Vitamins
Pyridoxylamine is an advanced glycation end production (AGEs) and lipoxidation end products (ALEs) inhibitor, to protect against diabetes-induced retinal vascular lesions.

同义名列表

4 个代谢物同义名

Pyridoxylamine; pyridoxamine; Pyridoxamine; Pyridoxamine



数据库引用编号

47 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(4)

BioCyc(1)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

31 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Aliah R Alshanwani, Hanan Hagar, Sameerah Shaheen, Ahlam M Alhusaini, Maha M Arafah, Laila M Faddah, Fatima Mb Alharbi, Arun K Sharma, Amel Fayed, Amira M Badr. A promising antifibrotic drug, pyridoxamine attenuates thioacetamide-induced liver fibrosis by combating oxidative stress, advanced glycation end products, and balancing matrix metalloproteinases. European journal of pharmacology. 2022 May; 923(?):174910. doi: 10.1016/j.ejphar.2022.174910. [PMID: 35339478]
  • Pratim Sengupta, Sumanta Biswas, Tapas Roy. Comparative Study to Evaluate the Effect of Low-Protein Diet Supplementation with Taurine and N-Acetylcysteine, N-Acetylcysteine and Pyridoxamine Dihydrochloride in Preventing the Progression of Chronic Renal Failure in Patients with Non-Diabetic Kidney Disease. The Journal of the Association of Physicians of India. 2022 May; 70(5):11-12. doi: . [PMID: 35598122]
  • Zhi-Bin Li, Li-Ying Shi, Yu-Shuai Han, Jing Chen, Shan-Qiang Zhang, Jia-Xi Chen, Jun Liu, Hui-Hui Tu, Qi-Qi Lu, Yi Yu, Ting-Ting Jiang, Ji-Cheng Li. Pyridoxal phosphate, pyridoxamine phosphate, and folic acid based on ceRNA regulatory network as potential biomarkers for the diagnosis of pulmonary tuberculosis. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 2022 04; 99(?):105240. doi: 10.1016/j.meegid.2022.105240. [PMID: 35150890]
  • Minfei Jiang, Aobuliaximu Yakupu, Haonan Guan, Jiaoyun Dong, Yingkai Liu, Fei Song, Jiajun Tang, Ming Tian, Yiwen Niu, Shuliang Lu. Pyridoxamine ameliorates methylglyoxal-induced macrophage dysfunction to facilitate tissue repair in diabetic wounds. International wound journal. 2022 Jan; 19(1):52-63. doi: 10.1111/iwj.13597. [PMID: 33792156]
  • Mathias D G Van den Eynde, Jean L J M Scheijen, Coen D A Stehouwer, Toshio Miyata, Casper G Schalkwijk. Quantification of the B6 vitamers in human plasma and urine in a study with pyridoxamine as an oral supplement; pyridoxamine as an alternative for pyridoxine. Clinical nutrition (Edinburgh, Scotland). 2021 07; 40(7):4624-4632. doi: 10.1016/j.clnu.2021.05.028. [PMID: 34229268]
  • Ghada Rashad Ibrahim, Iltaf Shah, Salah Gariballa, Javed Yasin, James Barker, Syed Salman Ashraf. Significantly Elevated Levels of Plasma Nicotinamide, Pyridoxal, and Pyridoxamine Phosphate Levels in Obese Emirati Population: A Cross-Sectional Study. Molecules (Basel, Switzerland). 2020 Aug; 25(17):. doi: 10.3390/molecules25173932. [PMID: 32872122]
  • Evelyn Nunes Goulart da Silva Pereira, Raquel Rangel Silvares, Edgar Eduardo Ilaquita Flores, Karine Lino Rodrigues, Anissa Daliry. Pyridoxamine improves metabolic and microcirculatory complications associated with nonalcoholic fatty liver disease. Microcirculation (New York, N.Y. : 1994). 2020 04; 27(3):e12603. doi: 10.1111/micc.12603. [PMID: 31876010]
  • Jasper B J Kamphuis, Bruno Guiard, Mathilde Leveque, Maiwenn Olier, Isabelle Jouanin, Sophie Yvon, Valerie Tondereau, Pauline Rivière, Françoise Guéraud, Sylvie Chevolleau, Maria-Helena Noguer-Meireles, Jean-François Martin, Laurent Debrauwer, Helene Eutamène, Vassilia Theodorou. Lactose and Fructo-oligosaccharides Increase Visceral Sensitivity in Mice via Glycation Processes, Increasing Mast Cell Density in Colonic Mucosa. Gastroenterology. 2020 02; 158(3):652-663.e6. doi: 10.1053/j.gastro.2019.10.037. [PMID: 31711923]
  • Seyeon Oh, Hyosang Ahn, Hyunjin Park, Jae-Ik Lee, Kook Yang Park, Daehee Hwang, Sojung Lee, Kuk Hui Son, Kyunghee Byun. The attenuating effects of pyridoxamine on adipocyte hypertrophy and inflammation differ by adipocyte location. The Journal of nutritional biochemistry. 2019 10; 72(?):108173. doi: 10.1016/j.jnutbio.2019.04.001. [PMID: 31499381]
  • Ying Wang, Ying Li, Zhiping Yang, Ziqiang Wang, Jiang Chang, Tao Zhang, Yanqing Chi, Ning Han, Kunxiao Zhao. Pyridoxamine Treatment of HK-2 Human Proximal Tubular Epithelial Cells Reduces Oxidative Stress and the Inhibition of Autophagy Induced by High Glucose Levels. Medical science monitor : international medical journal of experimental and clinical research. 2019 Feb; 25(?):1480-1488. doi: 10.12659/msm.914799. [PMID: 30799433]
  • Gyuree Kim, Sejeong Jang, Eun Kyung Yoon, Shin Ae Lee, Souvik Dhar, Jinkwon Kim, Myeong Min Lee, Jun Lim. Involvement of Pyridoxine/Pyridoxamine 5'-Phosphate Oxidase (PDX3) in Ethylene-Induced Auxin Biosynthesis in the Arabidopsis Root. Molecules and cells. 2018 Dec; 41(12):1033-1044. doi: 10.14348/molcells.2018.0363. [PMID: 30453730]
  • K M Abdullah, Faizan Abul Qais, Iqbal Ahmad, Hamza Hasan, Imrana Naseem. Study of pyridoxamine against glycation and reactive oxygen species production in human serum albumin as model protein: An in vitro & ex vivo approach. International journal of biological macromolecules. 2018 Dec; 120(Pt B):1734-1743. doi: 10.1016/j.ijbiomac.2018.09.176. [PMID: 30268752]
  • Matthew Hanson, Peter Zahradka, Carla G Taylor, Michel Aliani. Identification of urinary metabolites with potential blood pressure-lowering effects in lentil-fed spontaneously hypertensive rats. European journal of nutrition. 2018 Feb; 57(1):297-308. doi: 10.1007/s00394-016-1319-5. [PMID: 27770189]
  • Masanari Itokawa, Mitsuhiro Miyashita, Makoto Arai, Takashi Dan, Katsuyoshi Takahashi, Taro Tokunaga, Kayo Ishimoto, Kazuya Toriumi, Tomoe Ichikawa, Yasue Horiuchi, Akiko Kobori, Satoshi Usami, Takeo Yoshikawa, Naoji Amano, Shinsuke Washizuka, Yuji Okazaki, Toshio Miyata. Pyridoxamine: A novel treatment for schizophrenia with enhanced carbonyl stress. Psychiatry and clinical neurosciences. 2018 Jan; 72(1):35-44. doi: 10.1111/pcn.12613. [PMID: 29064136]
  • Seon Hwa Lee, Atsushi Matsunaga, Tomoyuki Oe. Inhibition effect of pyridoxamine on lipid hydroperoxide-derived modifications to human serum albumin. PloS one. 2018; 13(4):e0196050. doi: 10.1371/journal.pone.0196050. [PMID: 29672562]
  • Dorien Deluyker, Vesselina Ferferieva, Ronald B Driesen, Maxim Verboven, Ivo Lambrichts, Virginie Bito. Pyridoxamine improves survival and limits cardiac dysfunction after MI. Scientific reports. 2017 11; 7(1):16010. doi: 10.1038/s41598-017-16255-y. [PMID: 29167580]
  • D W Sullivan, R C Peterson, C V Mujer, S C Gad. A 7-day intravenous toxicity study and neurotoxicity assessment of pyridorin in Sprague-Dawley rats. Human & experimental toxicology. 2017 Jul; 36(7):718-726. doi: 10.1177/0960327116661023. [PMID: 27507076]
  • Kohei Dainin, Ryoko Ide, Ayumi Maeda, Kyozo Suyama, Mitsugu Akagawa. Pyridoxamine scavenges protein carbonyls and inhibits protein aggregation in oxidative stress-induced human HepG2 hepatocytes. Biochemical and biophysical research communications. 2017 05; 486(3):845-851. doi: 10.1016/j.bbrc.2017.03.147. [PMID: 28359757]
  • F Chiazza, A S Cento, D Collotta, D Nigro, G Rosa, F Baratta, V Bitonto, J C Cutrin, M Aragno, R Mastrocola, M Collino. Protective Effects of Pyridoxamine Supplementation in the Early Stages of Diet-Induced Kidney Dysfunction. BioMed research international. 2017; 2017(?):2682861. doi: 10.1155/2017/2682861. [PMID: 29214163]
  • Yoshitaka Mori, Takatoshi Kakuta, Takayo Miyakogawa, Susumu Takekoshi, Hiroko Yuzawa, Hiroyuki Kobayashi, Atsushi Kawakami, Toshio Miyata, Masafumi Fukagawa. Effect of Scavenging Circulating Reactive Carbonyls by Oral Pyridoxamine in Uremic Rats on Peritoneal Dialysis. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy. 2016 Dec; 20(6):645-654. doi: 10.1111/1744-9987.12446. [PMID: 27620210]
  • Jingnan Chen, Danqian Cai, Yu Zhang. Rapid determination of lipid peroxidation using a novel pyridoxamine-participating ferrous oxidation-sulfosalicylic acid spectrophotometric method. Food chemistry. 2016 Nov; 211(?):637-44. doi: 10.1016/j.foodchem.2016.05.106. [PMID: 27283678]
  • Matthew D Breyer, Katalin Susztak. Developing Treatments for Chronic Kidney Disease in the 21st Century. Seminars in nephrology. 2016 11; 36(6):436-447. doi: 10.1016/j.semnephrol.2016.08.001. [PMID: 27987541]
  • Déborah Mathis, Lucia Abela, Monique Albersen, Céline Bürer, Lisa Crowther, Karin Beese, Hans Hartmann, Levinus A Bok, Eduard Struys, Sorina M Papuc, Anita Rauch, Martin Hersberger, Nanda M Verhoeven-Duif, Barbara Plecko. The value of plasma vitamin B6 profiles in early onset epileptic encephalopathies. Journal of inherited metabolic disease. 2016 09; 39(5):733-741. doi: 10.1007/s10545-016-9955-8. [PMID: 27342130]
  • Daniel Wong, Xiaoqiang Hu, Ningping Tao, Xichang Wang, Mingfu Wang. Effect and mechanism of pyridoxamine on the lipid peroxidation and stability of polyunsaturated fatty acids in beef patties. Journal of the science of food and agriculture. 2016 Aug; 96(10):3418-23. doi: 10.1002/jsfa.7522. [PMID: 26538517]
  • Nataliya I Skrypnyk, Paul Voziyan, Haichun Yang, Christian R de Caestecker, Marie-Claude Theberge, Mathieu Drouin, Billy Hudson, Raymond C Harris, Mark P de Caestecker. Pyridoxamine reduces postinjury fibrosis and improves functional recovery after acute kidney injury. American journal of physiology. Renal physiology. 2016 08; 311(2):F268-77. doi: 10.1152/ajprenal.00056.2016. [PMID: 27194713]
  • Julio E Pena-Polanco, Linda F Fried. Established and Emerging Strategies in the Treatment of Chronic Kidney Disease. Seminars in nephrology. 2016 07; 36(4):331-42. doi: 10.1016/j.semnephrol.2016.05.009. [PMID: 27475663]
  • Maite Colinas, Marion Eisenhut, Takayuki Tohge, Marta Pesquera, Alisdair R Fernie, Andreas P M Weber, Teresa B Fitzpatrick. Balancing of B6 Vitamers Is Essential for Plant Development and Metabolism in Arabidopsis. The Plant cell. 2016 Feb; 28(2):439-53. doi: 10.1105/tpc.15.01033. [PMID: 26858304]
  • Simone Pereira-Simon, Gustavo A Rubio, Xiaomei Xia, Weijing Cai, Rhea Choi, Gary E Striker, Sharon J Elliot. Inhibition of Advanced Glycation End Products (AGEs) Accumulation by Pyridoxamine Modulates Glomerular and Mesangial Cell Estrogen Receptor α Expression in Aged Female Mice. PloS one. 2016; 11(7):e0159666. doi: 10.1371/journal.pone.0159666. [PMID: 27428057]
  • Tarek Kamal Abouzed, Seiichi Munesue, Ai Harashima, Yusuke Masuo, Yukio Kato, Khaled Khailo, Hiroshi Yamamoto, Yasuhiko Yamamoto. Preventive Effect of Salicylate and Pyridoxamine on Diabetic Nephropathy. Journal of diabetes research. 2016; 2016(?):1786789. doi: 10.1155/2016/1786789. [PMID: 28042580]
  • Hartman Madu, Josh Avance, Sergei Chetyrkin, Carl Darris, Kristie Lindsey Rose, Otto A Sanchez, Billy Hudson, Paul Voziyan. Pyridoxamine protects proteins from damage by hypohalous acids in vitro and in vivo. Free radical biology & medicine. 2015 Dec; 89(?):83-90. doi: 10.1016/j.freeradbiomed.2015.07.001. [PMID: 26159508]
  • Venkataraman Amarnath, Kalyani Amarnath. Scavenging 4-Oxo-2-nonenal. Chemical research in toxicology. 2015 Oct; 28(10):1888-90. doi: 10.1021/acs.chemrestox.5b00301. [PMID: 26355561]
  • Elisa Oppici, Sonia Fargue, Emma S Reid, Philippa B Mills, Peter T Clayton, Christopher J Danpure, Barbara Cellini. Pyridoxamine and pyridoxal are more effective than pyridoxine in rescuing folding-defective variants of human alanine:glyoxylate aminotransferase causing primary hyperoxaluria type I. Human molecular genetics. 2015 Oct; 24(19):5500-11. doi: 10.1093/hmg/ddv276. [PMID: 26199318]
  • Keita Kato, Nobukazu Shitan, Tsubasa Shoji, Takashi Hashimoto. Tobacco NUP1 transports both tobacco alkaloids and vitamin B6. Phytochemistry. 2015 May; 113(?):33-40. doi: 10.1016/j.phytochem.2014.05.011. [PMID: 24947336]
  • Amit D Raval, Divyesh Thakker, Arohi N Rangoonwala, Deval Gor, Rama Walia. Vitamin B and its derivatives for diabetic kidney disease. The Cochrane database of systematic reviews. 2015 Jan; 1(?):CD009403. doi: 10.1002/14651858.cd009403.pub2. [PMID: 25579852]
  • Monique Albersen, Marjolein Bosma, Judith J M Jans, Floris C Hofstede, Peter M van Hasselt, Monique G M de Sain-van der Velden, Gepke Visser, Nanda M Verhoeven-Duif. Vitamin B6 in plasma and cerebrospinal fluid of children. PloS one. 2015; 10(3):e0120972. doi: 10.1371/journal.pone.0120972. [PMID: 25760040]
  • Sooyoun Seo, Salwa Karboune. Investigation of the use of Maillard reaction inhibitors for the production of patatin-carbohydrate conjugates. Journal of agricultural and food chemistry. 2014 Dec; 62(50):12235-43. doi: 10.1021/jf502497r. [PMID: 25400165]
  • Zhenyu Dong, Daiju Iwata, Nobuyoshi Kitaichi, Masayoshi Takeuchi, Masashi Sato, Noriko Endo, Kazuya Iwabuchi, Ryo Ando, Junichi Fukuhara, Satoshi Kinoshita, Anton Lennikov, Mizuki Kitamura, Kazuomi Mizuuchi, Atsuhiro Kanda, Kousuke Noda, Kenichi Namba, Sho-Ichi Yamagishi, Shigeaki Ohno, Susumu Ishida. Amelioration of experimental autoimmune uveoretinitis by inhibition of glyceraldehyde-derived advanced glycation end-product formation. Journal of leukocyte biology. 2014 Dec; 96(6):1077-85. doi: 10.1189/jlb.3a0513-288rrr. [PMID: 25201803]
  • Makoto Arai, Mitsuhiro Miyashita, Akiko Kobori, Kazuya Toriumi, Yasue Horiuchi, Masanari Itokawa. Carbonyl stress and schizophrenia. Psychiatry and clinical neurosciences. 2014 Sep; 68(9):655-65. doi: 10.1111/pcn.12216. [PMID: 24995521]
  • Monique Albersen, Marjolein Bosma, Jurjen J Luykx, Judith J M Jans, Steven C Bakker, Eric Strengman, Paul J Borgdorff, Peter J M Keijzers, Eric P A van Dongen, Peter Bruins, Monique G M de Sain-van der Velden, Gepke Visser, Nine V V A M Knoers, Roel A Ophoff, Nanda M Verhoeven-Duif. Vitamin B-6 vitamers in human plasma and cerebrospinal fluid. The American journal of clinical nutrition. 2014 Aug; 100(2):587-92. doi: 10.3945/ajcn.113.082008. [PMID: 24808484]
  • Sergio Stefoni, Giuseppe Cianciolo, Olga Baraldi, Mario Iorio, Maria Laura Angelini. Emerging drugs for chronic kidney disease. Expert opinion on emerging drugs. 2014 Jun; 19(2):183-99. doi: 10.1517/14728214.2014.900044. [PMID: 24836744]
  • Tyson L Ware, John Earl, Gajja S Salomons, Eduard A Struys, Heidi L Peters, Katherine B Howell, James J Pitt, Jeremy L Freeman. Typical and atypical phenotypes of PNPO deficiency with elevated CSF and plasma pyridoxamine on treatment. Developmental medicine and child neurology. 2014 May; 56(5):498-502. doi: 10.1111/dmcn.12346. [PMID: 24266778]
  • Radica Z Alicic, Katherine R Tuttle. Novel therapies for diabetic kidney disease. Advances in chronic kidney disease. 2014 Mar; 21(2):121-33. doi: 10.1053/j.ackd.2014.01.007. [PMID: 24602462]
  • ShuoHao Huang, JianYun Zhang, Mei Wu, Qiong Wu, LongQuan Huang. Enzymatic transamination of pyridoxamine in tobacco plants. Plant science : an international journal of experimental plant biology. 2013 Nov; 212(?):55-9. doi: 10.1016/j.plantsci.2013.08.001. [PMID: 24094054]
  • Casey D Charvet, Aicha Saadane, Meiyao Wang, Robert G Salomon, Henri Brunengraber, Illarion V Turko, Irina A Pikuleva. Pretreatment with pyridoxamine mitigates isolevuglandin-associated retinal effects in mice exposed to bright light. The Journal of biological chemistry. 2013 Oct; 288(41):29267-80. doi: 10.1074/jbc.m113.498832. [PMID: 23970548]
  • Shabnam Garg, Ashit Syngle, Kanchan Vohra. Efficacy and tolerability of advanced glycation end-products inhibitor in osteoarthritis: a randomized, double-blind, placebo-controlled study. The Clinical journal of pain. 2013 Aug; 29(8):717-24. doi: 10.1097/ajp.0b013e318272ebec. [PMID: 23354008]
  • Mohamed M Elseweidy, Sahar E Elswefy, Nahla N Younis, Mohamed S Zaghloul. Pyridoxamine, an inhibitor of protein glycation, in relation to microalbuminuria and proinflammatory cytokines in experimental diabetic nephropathy. Experimental biology and medicine (Maywood, N.J.). 2013 Aug; 238(8):881-8. doi: 10.1177/1535370213494644. [PMID: 23970406]
  • ShuoHao Huang, JianYun Zhang, LingHong Wang, LongQuan Huang. Effect of abiotic stress on the abundance of different vitamin B6 vitamers in tobacco plants. Plant physiology and biochemistry : PPB. 2013 May; 66(?):63-7. doi: 10.1016/j.plaphy.2013.02.010. [PMID: 23500708]
  • Caronda J Moore, Chun Hong Shao, Ryoji Nagai, Shelby Kutty, Jaipaul Singh, Keshore R Bidasee. Malondialdehyde and 4-hydroxynonenal adducts are not formed on cardiac ryanodine receptor (RyR2) and sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA2) in diabetes. Molecular and cellular biochemistry. 2013 Apr; 376(1-2):121-35. doi: 10.1007/s11010-013-1558-1. [PMID: 23354458]
  • Magdalena Jankowska, Marcin Marszałł, Alicja Dębska-Ślizień, Juan J Carrero, Bengt Lindholm, Wojciech Czarnowski, Bolesław Rutkowski, Piotr Trzonkowski. Vitamin B6 and the immunity in kidney transplant recipients. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation. 2013 Jan; 23(1):57-64. doi: 10.1053/j.jrn.2012.01.023. [PMID: 22445054]
  • B Fernández Fernández, U Elewa, M D Sánchez-Niño, J E Rojas-Rivera, C Martin-Cleary, J Egido, A Ortiz. 2012 update on diabetic kidney disease: the expanding spectrum, novel pathogenic insights and recent clinical trials. Minerva medica. 2012 Aug; 103(4):219-34. doi: . [PMID: 22805616]
  • ShuoHao Huang, JianYun Zhang, YaPing Ma, Shu Wei, LongQuan Huang. Characterization of an acid phosphatase responsible for hydrolysis of pyridoxal 5'-phosphate in tobacco plants. Plant physiology and biochemistry : PPB. 2012 Aug; 57(?):114-9. doi: 10.1016/j.plaphy.2012.05.017. [PMID: 22698754]
  • Brian Shepler, Christy Nash, Cory Smith, Abbey Dimarco, Josie Petty, Stephanie Szewciw. Update on potential drugs for the treatment of diabetic kidney disease. Clinical therapeutics. 2012 Jun; 34(6):1237-46. doi: 10.1016/j.clinthera.2012.04.026. [PMID: 22578309]
  • Anna Dietrich-Muszalska, Joanna Malinowska, Beata Olas, Rafal Głowacki, Edward Bald, Barbara Wachowicz, Jolanta Rabe-Jabłońska. The oxidative stress may be induced by the elevated homocysteine in schizophrenic patients. Neurochemical research. 2012 May; 37(5):1057-62. doi: 10.1007/s11064-012-0707-3. [PMID: 22270909]
  • Teruo Miyazawa, Kiyotaka Nakagawa, Satoko Shimasaki, Ryoji Nagai. Lipid glycation and protein glycation in diabetes and atherosclerosis. Amino acids. 2012 Apr; 42(4):1163-70. doi: 10.1007/s00726-010-0772-3. [PMID: 20957396]
  • Katrien H J Gaens, Petra M G Niessen, Sander S Rensen, Wim A Buurman, Jan Willem M Greve, Ann Driessen, Marcel G M Wolfs, Marten H Hofker, Johanne G Bloemen, Cornelis H Dejong, Coen D A Stehouwer, Casper G Schalkwijk. Endogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis. Journal of hepatology. 2012 Mar; 56(3):647-55. doi: 10.1016/j.jhep.2011.07.028. [PMID: 21907687]
  • Pengli Zhu, Hong Lin, Chengai Sun, Fan Lin, Huizhen Yu, Xiuping Zhuo, Chanjuan Zhou, Zhisheng Deng. Synergistic effects of telmisartan and pyridoxamine on early renal damage in spontaneously hypertensive rats. Molecular medicine reports. 2012 03; 5(3):655-62. doi: 10.3892/mmr.2011.717. [PMID: 22200727]
  • Yasuhiko Tomino. Mechanisms and interventions in peritoneal fibrosis. Clinical and experimental nephrology. 2012 Feb; 16(1):109-14. doi: 10.1007/s10157-011-0533-y. [PMID: 21935614]
  • Ashit Syngle, Kanchan Vohra, Nidhi Garg, Ladbans Kaur, Prem Chand. Advanced glycation end-products inhibition improves endothelial dysfunction in rheumatoid arthritis. International journal of rheumatic diseases. 2012 Feb; 15(1):45-55. doi: 10.1111/j.1756-185x.2011.01679.x. [PMID: 22324946]
  • Huong Thi Viet Do, Youhei Ide, Andrew Njagi Mugo, Toshiharu Yagi. All-enzymatic HPLC method for determination of individual and total contents of vitamin B(6) in foods. Food & nutrition research. 2012; 56(?):. doi: 10.3402/fnr.v56i0.5409. [PMID: 22481897]
  • Makoto Arai, Mitsuhiro Miyashita, Tomoe Ichikawa, Masanari Itokawa. [Carbonyl stress-related schizophrenia--perspective on future therapy and hypotheses regarding pathophysiology of schizophrenia]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. 2012; 114(3):199-208. doi: . [PMID: 22568054]
  • Paula M Chilton, Chelsea A Embry, Thomas C Mitchell. Effects of Differences in Lipid A Structure on TLR4 Pro-Inflammatory Signaling and Inflammasome Activation. Frontiers in immunology. 2012; 3(?):154. doi: 10.3389/fimmu.2012.00154. [PMID: 22707952]
  • Edmund J Lewis, Tom Greene, Samuel Spitalewiz, Samuel Blumenthal, Tomas Berl, Lawrence G Hunsicker, Marc A Pohl, Richard D Rohde, Itamar Raz, Yair Yerushalmy, Yoram Yagil, Tommy Herskovits, Robert C Atkins, Anne T Reutens, David K Packham, Julia B Lewis. Pyridorin in type 2 diabetic nephropathy. Journal of the American Society of Nephrology : JASN. 2012 Jan; 23(1):131-6. doi: 10.1681/asn.2011030272. [PMID: 22034637]
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